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    11 research outputs found

    Licorice Root Resulting in Admission to the Intensive Care Unit

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    INTRODUCTION Patients commonly use herbal and food supplements and may often assume that a product is safe because it is “natural”; however, many of these products are just as dangerous as any prescription drug. This case report describes the admission of a patient to the intensive care unit after consumption of a food supplement containing licorice root (Glycyrrhiza sp.). The purpose of this report is to illustrate that commonly overlooked items in medication histories, such as food supplements, may lead to life-threatening complications. Detailed history-taking and investigation of herbal products identified in a medication history is essential to good pharmaceutical care
    The Canadian Journal of Hospital Pharmacy (CJHP) / Le Journal canadien de la pharmacie hospitalière (JCPH)

    Mentorship in a Canadian residency program: faculty and resident needs and experiences

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    Crossref

    Cricoid Pressure Provides Incomplete Esophageal Occlusion Associated with Lateral Deviation: A Magnetic Resonance Imaging Study

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    Background: Cricoid pressure is a routine component of rapid sequence induction and is designed to reduce the risk of reflux and its associated morbidity. Recent studies have raised questions regarding the efficacy of cricoid pressure in terms of changes in the pharyngeal and esophageal anatomy. Objective: This current descriptive study was designed to observe the anatomical effect of cricoid pressure on the occlusion of esophageal lumen in conscious volunteers using magnetic resonance imaging (MRI). Methods: We quantitatively assessed esophageal patency before and during application of cricoid pressure in 20 awake volunteers utilizing MRI. Results: Target cricoid pressure was achieved in 16 of 20 individuals, corresponding to a mean percentage reduction in cricovertebral distance of 43% (range 25-80%). Cricoid pressure was applied incorrectly in 4 (20%) individuals as evidenced by no change in the cricovertebral distance. Incomplete esophageal occlusion was seen in 10 of 16, or 62.5% (95% confidence interval 35-85%) of individuals when appropriate cricoid pressure was applied. Incomplete esophageal occlusion was always associated with a lateral deviation of the esophagus. None of the 6 subjects with complete occlusion had esophageal deviation during the appropriate application of cricoid pressure. Conclusion: Effective application of cricoid pressure by an experienced operator frequently resulted in lateral deviation of the esophagus and incomplete occlusion of esophageal lumen. Reliance on cricoid pressure for esophageal occlusion requires further evaluation utilizing functional studies.</p
    Crossref
    Archive ouverte UNIGE

    Intraoperative ketorolac dose of 15 mg versus the standard 30 mg on early postoperative pain after spine surgery: A randomized, blinded, non-inferiority trial

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    Crossref

    Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

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    Nestle Health Sciences
    Crossref
    IRIS UniSR (’Università Vita-Salute San Raffaele)
    UNIL IRIS | Institutional Research Information System
    Ghent University Academic Bibliography
    Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna
    ZORA
    Archivio istituzionale della ricerca - Università di Ferrara
    Queen Mary Research Online
    White Rose Research Online
    Utrecht University Repository
    George Washington University: Health Sciences Research Commons (HSRC)

    Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery.

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    Background: The incidence and impact of postoperative complications are poorly described. Failure-to-rescue, the rate of death following complications, is an important quality measure for perioperative care but has not been investigated across multiple health care systems. Methods: We analysed data collected during the International Surgical Outcomes Study, an international 7-day cohort study of adults undergoing elective inpatient surgery. Hospitals were ranked by quintiles according to surgical procedural volume (Q1 lowest to Q5 highest). For each quintile we assessed in-hospital complications rates, mortality, and failure-to-rescue. We repeated this analysis ranking hospitals by risk-adjusted complication rates (Q1 lowest to Q5 highest). Results: A total of 44 814 patients from 474 hospitals in 27 low-, middle-, and high-income countries were available for analysis. Of these, 7508 (17%) developed one or more postoperative complication, with 207 deaths in hospital (0.5%), giving an overall failure-to-rescue rate of 2.8%. When hospitals were ranked in quintiles by procedural volume, we identified a three-fold variation in mortality (Q1: 0.6% vs Q5: 0.2%) and a two-fold variation in failure-to-rescue (Q1: 3.6% vs Q5: 1.7%). Ranking hospitals in quintiles by risk-adjusted complication rate further confirmed the presence of important variations in failure-to-rescue, indicating differences between hospitals in the risk of death among patients after they develop complications. Conclusions: Comparison of failure-to-rescue rates across health care systems suggests the presence of preventable postoperative deaths. Using such metrics, developing nations could benefit from a data-driven approach to quality improvement, which has proved effective in high-income countries
    University of Groningen
    UNIL IRIS | Institutional Research Information System
    The University of Manchester - Institutional Repository
    Queen Mary Research Online
    George Washington University: Health Sciences Research Commons (HSRC)
    Crossref
    Online Research @ Cardiff
    Ghent University Academic Bibliography
    Institutional Repository Universiteit Antwerpen
    St George's Online Research Archive

    In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study

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    Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London
    Crossref
    Online Research @ Cardiff
    University of Groningen
    UNIL IRIS | Institutional Research Information System
    Ghent University Academic Bibliography
    Institutional Repository Universiteit Antwerpen
    VBN (Videnbasen) Aalborg Universitets forskningsportal
    The University of Manchester - Institutional Repository
    Queen Mary Research Online
    St George's Online Research Archive

    Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

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    This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London
    University of Birmingham Research Portal
    UNIL IRIS | Institutional Research Information System
    Archivio istituzionale della ricerca - Università dell'Insubria
    FreiDok plus
    Open Repository and Bibliography - Liège
    The University of Manchester - Institutional Repository
    Queen Mary Research Online
    Repositório da Unidade Local de Saúde São José
    George Washington University: Health Sciences Research Commons (HSRC)
    HKU Scholars Hub
    UQ eSpace (University of Queensland)
    Crossref
    Archivio istituzionale della Ricerca - Università degli Studi di Parma
    Ghent University Academic Bibliography
    UCL Discovery
    Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna
    Utrecht University Repository
    Archivio della ricerca- Università di Roma La Sapienza
    Explore Bristol Research

    Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries The International Surgical Outcomes Study group

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    Funded by Nestle Health Sciences through an unrestricted research grant, by a National Institute for Health Research Professorship held by R.P., and sponsored by Queen Mary University of London
    Aberdeen University Research
    University of Groningen
    Archivio istituzionale della ricerca - Università dell'Insubria
    Open Repository and Bibliography - Liège
    George Washington University: Health Sciences Research Commons (HSRC)
    Archivio istituzionale della Ricerca - Università degli Studi di Parma
    Ghent University Academic Bibliography
    Oxford University Research Archive
    Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna
    University of Melbourne Institutional Repository
    Monash University Research Portal
    Southampton (e-Prints Soton)
    UNIL IRIS | Institutional Research Information System
    PEARL (Univ. of Plymouth)
    Spiral - Imperial College Digital Repository
    The University of Manchester - Institutional Repository
    Queen Mary Research Online
    Repositório da Unidade Local de Saúde São José
    UQ eSpace (University of Queensland)
    Maastricht University Research Portal
    UCL Discovery
    St George's Online Research Archive
    Swepub

    In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study

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    In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational stud
    DRO Deakin Research Online
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