1,720,952 research outputs found
Refractory arterial hypertension: clinical manifestations and controversies
Full text linkKarpenko Yuriy I., Garmazi Saber. Refractory arterial hypertension: clinical manifestations and controversies. Journal of Education, Health and Sport. 2015;5(11):238-244. ISSN 2391-8306. DOIhttp://dx.doi.org/10.5281/zenodo.33900
http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%2811%29%3A238-244
https://pbn.nauka.gov.pl/works/669685
Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011–2014http://journal.rsw.edu.pl/index.php/JHS/issue/archive
Deklaracja.
Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.
Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.
The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).
© The Author (s) 2015;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 25.09.2015. Revised 25.10.2015. Accepted: 10.11.2015.
Refractory arterial hypertension: clinical manifestations and controversies
Karpenko Yuriy I., Garmazi Saber
Odessa National Medical University, Odessa, Ukraine
Abstract
The study was aimed to assess the clinical manifestations in patients with refractory hypertension. There was demonstrated that refractory arterial hypertension is characterized with hyperactivation of sympathetic nervous system. Patients with RAH used 4,6 ± 0,2 medications to control the pressure. The most common combinations are the combination of blockers, ACE inhibitors and diuretics, ACE inhibitors and diuretics, and, ACC, more rarely, patients received a combination of ARB and a diuretic ACC. Every third patient in therapy included 4 or more antihypertensive drugs, that is, there was a polypharmacy. However the combination of used medications and their dosage regimen does not achieve significant clinical effect.
Key words: arterial hypertension, medication resistance, diagnostics, monitoring
A Finite Element Analysis Investigation of Fatigue and Corrosion of Floating Offshore Wind Turbine Mooring Lines
No full textWith the rising demand for renewable energy, floating offshore wind turbines have gained importance, particularly in regions where deep waters prevent the use of traditional monopile structures. These floating turbines rely on mooring lines for stability against environmental conditions, particularly when facing strong winds and high waves. Ensuring a satisfactory lifetime and health of mooring lines is critical. Moreover, degradation can compromise the turbine’s functionality or even lead to catastrophic failures. While direct monitoring is ideal, it is often hampered by high costs and extensive maintenance. This Master’s thesis introduces a novel method to assess mooring line degradation. The proposed approach simulates the impact of environmental conditions on the mooring lines, considering various forces and weather scenarios. The research presents modeling of fatigue and corrosion effects along the mooring line. A unique corrosion model calculates variations based on seawater’s oxygen and temperature profiles. Concurrently, mooring line stresses are deduced from real-world environmental conditions. Integrating these, a finite element model is constructed to analyze different load scenarios and the onset of corrosion on line degradation. The model considers the joint impact of corrosion and fatigue on mooring lines, including the influence of hydro static pressure and out-of-plane bending. Validation of this methodology draws upon existing research and experimental results on mooring lines.Offshore and Dredging Engineerin
Optimization of treatment of patients with ischemic heart disease after suffering intervention in the coronary arteries
Full text linkKarpenko Y. I., Blikhar O. V. Optimization of treatment of patients with ischemic heart disease after suffering intervention in the coronary arteries. Journal of Education, Health and Sport. 2016;6(8):560-566. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.60962
http://ojs.ukw.edu.pl/index.php/johs/article/view/3774
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).
755 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Author (s) 2016;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 01.08.2016. Revised 08.08.2016. Accepted: 26.08.2016.
Optimization of treatment of patients with ischemic heart disease after suffering intervention in the coronary arteries
Y. I. Karpenko, O. V. Blikhar
Odesa national medical university, Odesa, Ukraine
Abstract
Each year increase number of patients with ischemic heart disease (IHD), according to this rising costs of treating this group of patients and increase amount of complications of IHD. Also is actual question of management of patients with IHD after surgery interventions, particularly after stenting or coronary artery bypass grafting (CABG). Risk factors are strongly increase in the patients with diabetes mellitus (DM) type 2. For them is more common damaging the coronary artery on big distance, violation of microcirculation and silent form of IHD. All this often lead to late diagnosis of IHD. Given the above, developing new methods of treatments for this cohort of patients. One of them - a method of cardiac shock wave therapy (CSWT). The mechanism of action of CSWT is based on a direct effect of shock waves at a specific segment of the heart, and remote influence on neoangiogenesis and improving the microvascularization. We compared the efficacy of treatment in patients with IHD and DM type 2 after CABG or stenting conducted on background of standard therapy compared with use in the treatment method CSWT. The effectiveness of treatment at this stage of work was evaluated by the number of angina attacks and contractile capacity of left ventricular according data of Echocardioscopy. The maximum efficiency of the method observed at 6 months of treatment with using CSWT. Long-term results in a reduction in angina and improving myocardial contractile capacity recorded in the group of patients treated with CSWT.
Keywords: cardiac shock wave therapy, ischemic heart disease, diabetes mellitus type 2
Titanium alloy corrosion fatigue crack growth rates prediction : peridynamics based numerical approach
Full text linkThis study presents a numerical approach for modelling the Corrosion Fatigue Crack Growth (CFCG) in conventional casting and additively manufactured Ti6Al4V alloys. The proposed numerical model, based on Peridynamics (PD), combines the PD Fatigue Crack Growth (FCG) model and PD diffusion model in order to couple the mechanical and diffusion fields existing in the material due to the impact of environmental fatigue. The mechanical field is responsible for the characterisation of the changes to the structure due to the fatigue loading conditions. The diffusion field is based on the modelling of the adsorbed-hydrogen Stress Corrosion Cracking (SCC), in particular, the Hydrogen Embrittlement (HE) model is considered. The proposed approach has been validated using experimental data available in the literature showing the capability of the tool to predict the CFCG rates
Verification of multi-axial damage in Glass Fibre-Reinforced Polymer laminates by progressive failure analysis for Civil Engineering applications
No full textThe use of Glass Fibre-Reinforced Polymer as a building material in structures or structural components is on the rise. Standards such as CUR96, DNV and JRC provide a basis of design with the material. However, there is a lack of confidence in the design phase with structures made of Glass Fibre-Reinforced Polymer, resulting in the use of large safety factors causing the components to be bloated in size. At the time of writing this report, the technical committee, CEN/TC 250 (responsible for developing structural Eurocodes), establishes a technical design specification for Fibre-Reinforced Polymer (FRP) structures. This technical specification describes a simplified and linear criterion to determine the capacity of a GFPR Laminate, in addition to being open for the use of Progressive Failure Analysis (PFA). However, the simplified and linear criterion is overly conservative, whereas there is a lack of faith in the use of the PFA considering the failure theories and degradation models that are currently in use. This report discusses the PFA, a non-linear, 5-step, advanced 2D analysis model, that can predict the static strength of in-plane stress dominated Glass Fibre-Reinforced Polymer laminate, with an arbitrary lay-up composition, based on existing knowledge and experiments, including the damage development under multi-axial stress states and stress redistribution. The research is limited to in-plane behavior, under tensile and compressive stresses. The static material response is characterized on a unidirectional ply level based on principal directions and based on experimental results obtained from the OptiDat program. The response predicted by the PFA for both tension and compression was in reasonable agreement with the experimental results. However, depending on the failure theory and degradation model used, there is potential for optimistic predictions of the laminate stress capacity. For future work, it is recommended to continue the research on a larger variety of laminate lay-ups and include more failure theories and degradation models.Civil Engineerin
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Bio-Based FRP Floors: A Comprehensive Feasibility Analysis: Structural, environmental, and economic performance in modular buildings compared to conventional floors
No full textThis research investigates the feasibility and potential of utilizing BFRP floors in modular buildings as a low environmental impact and cost-effective alternative to conventional floors. A modular building is introduced as a case study, the Natural Pavilion in Almere, to bring focus to the research and set a baseline for the requirements of the BFRP floor. A second case study, the bio-composite bridge in Ritsumasyl, is introduced to utilize its comprehensive dataset of material properties representing the state-of-the-art BFRP. Using the two case studies, two design solutions, a one-way and two-way floor, are developed.Comparing the designed BFRP floor to conventional floors such as cross-laminated timber, concrete hollow core slab, and concrete flat slab, several conclusions can be drawn:(1) The construction height of BFRP floors is similar to that of conventional floors. The weight of the floor is similar to a CLT floor, while a concrete floor is 6-8 times heavier. Design optimization is possible, and the amount of BFRP material utilized can be reduced by up to 21% for the one-way floor and 19% for the two-way floor. Additionally, the floor design proposed in this thesis is intended for buildings with a design life of 15 years and no specific fire resistance requirements. For structures with a design life of 50 years, it is imperative to increase the floor height to meet deflection criteria. Further research on fire resistance and additional measures is necessary to extend applicability beyond single-compartment buildings and terrace housing.(2) The environmental impact of a BFRP floor, assessed in terms of Global Warming Potential through a Life Cycle Analysis encompassing stages A1-A5, is found to be twice that of a concrete floor. Through optimization of the floor design and reduction of BFRP material usage, it is possible to achieve a reduction in CO2 emissions of approximately 10%. Nevertheless, in the current state-of-the-art, BFRP floors exhibit a higher environmental impact than conventional flooring systems. The use of resin and the production process are the primary contributors to CO2 emissions. The contribution from the production process requires nuance, as results heavily depend on the data source. Factors such as manufacturing techniques and production scale significantly affect this impact. By reducing the impact of the resin and production techniques while also exploring end-of-life possibilities for 100% bio-based BFRP, the environmental impact of BFRP floors holds potential for the future.(3) The floor cost is nearly twice as high as a comparable CLT floor. This can be attributed to introducing new design solutions with a sustainability focus, often resulting in increased costs due to lower demand, higher material and design expenses, and limited production scale. Even though current costs are much higher for BFRP floors than for conventional floors, there is potential for BFRP floors to become more cost-effective and competitive in the future, especially when the environmental impact is reduced. It is difficult to estimate how the price of BFRP floors would change over time, and therefore, it has not been taken into account in the results.Civil Engineering | Structural Engineering | Steel and Timber Constructio
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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