554 research outputs found
En narratologisk jämförelse mellan Karin Fossums Jonas Eckel och Kari Hotakainens Löpgravsvägen ur ett genusperspektiv
En narratologisk jämförelse mellan Karin Fossums Jonas Eckel och Kari Hotakainens Löpgravsvägen. Romanerna studeras även ur ett genusperspektiv
Family history in relation to myocardial infarction, and analyses of gene-environment interactions involving factors of haemostasis
Family history of coronary heart disease (CHD) has frequently been shown to increase the risk of MI. However, the mechanisms are not well understood. Probably, both genetic- and environmental effects contribute. It is possible that family history in combination with other cardiovascular risk factors is of particular importance in the aetiology of myocardial infarction (MI). Haemostatic factors seem to contribute in the causation of MI, although this is not established. Plasma fibrinogen and plasminogen activator inhibitor-1 (PAI-1) are two potentially important risk factors, with their genetic variants possibly influencing effects. The potential involvements of these factors in interactions with other cardiovascular risk factors are poorly understood.The aims of the present thesis were to assess the influence of family history of CHD on risk of first non-fatal MI in men and women, respectively, and to explore its potential role as a biologically interacting factor. The thesis also aimed to study the importance of fibrinogen and the G-455 A polymorphism, and PAI-1 and the 4G/5G polymorphism, in relation to risk of MI. Here a particular aim was also to explore potential synergistic effects for exposure combinations involving these factors regarding risk of MI. A final aim was to explore which cardiovascular risk factors may be most important for the long-term prognosis after a non-fatal MI.Data are derived from the Stockholm Heart Epidemiology Program (SHEEP), a populationbased case-control study of MI performed between 1992 and 1994 at the ten emergency hospitals within the county of Stockholm. The present analyses were restricted to 1643 men and women who had suffered a first-time non-fatal MI, and 2339 controls. Data on exposures were available from questionnaires, anthropometric measurements, blood samples, and medical records.A family history of CHD (defined as >=1 first-degree relative affected before the age of 65) was observed to be associated with risk of MI in both men and women. Synergistic effects were observed in women exposed to family history of CHD in combination with current smoking and with a high LDL/HDL quotient, respectively. In men, family history of CHD and diabetes mellitus seemed to act in synergy.High level of plasma fibrinogen was associated with increased risk of MI in both men and women, although the OR decreased after adjusting for other cardiovascular risk factors. Presence of the A-455 allele was associated with increased fibrinogen level but not with increased risk of MI. No clear synergistic effects were observed. High plasma PAI-1 activity was associated with increased risk of MI, and in men it also interacted with smoking in increasing the risk synergistically. In women, presence of the 4G allele was associated although weakly with increased risk of MI.Diabetes mellitus, job strain and abdominal adiposure had an impact on prognosis after MI in men. In women, prognostic importance was particularly noted for diabetes mellitus and for low level of Apolipoprotein AI. In both men and women the size of the initial infarction also had a prognostic value. In male survivors of MI, family history of CHD increased the risk of death from CHD during follow-up.In conclusion, this thesis suggests the occurrence of several biological interactions between risk factors for MI. The involvement of family history in such interactions indicates that gene-environment interaction may be in operation. After MI, several primary and secondary exposures have an influence on the prognosis.List of scientific papersI. Leander K, Hallqvist J, Reuterwall C, Ahlbom A, de Faire U (2001). Family history of coronary heart disease, a strong risk factor for myocardial infarction interacting with other cardiovascular risk factors: results from the Stockholm Heart Epidemiology Program (SHEEP). Epidemiology. 12(2): 215-21. https://pubmed.ncbi.nlm.nih.gov/11246583II. Leander K, Wiman B, Hallqvist J, Falk G, De Faire U (2002). The G-455A polymorphism of the fibrinogen Bbeta-gene relates to plasma fibrinogen in male cases, but does not interact with environmental factors in causing myocardial infarction in either men or women. J Intern Med. 252(4): 332-41. https://pubmed.ncbi.nlm.nih.gov/12366606III. Leander K, Wiman B, Hallqvist J, Sten-Linder M, de Faire U; Stockholm Heart Epidemiology Program (2003). PAI-1 level and the PAI-1 4G/5G polymorphism in relation to risk of non-fatal myocardial infarction: results from the Stockholm Heart Epidemiology Program (SHEEP). Thromb Haemost. 89(6): 1064-71. https://pubmed.ncbi.nlm.nih.gov/12783120IV. Leander K, Andersson T, Hallqvist J, Wiman B, Ahlbom A, de Faire U (2005). Cardiovascular risk factors - importance for risk of recurrent myocardial infarction. [Manuscript]</p
From gesenius to bauer-leander hebrew grammar and the challenge of comparative linguistics
This article analyses the influence of comparative grammars of semitic language on the study of hebrew in the 19 century. By comparing the works of Gesenius (1817) e Bauer & Leander (1918), the author points out some aspects of this influence in the 19 century, as well as the changes of perspective o occurred under the influence of 20 century Linguistics.Este artigo analisa a influência da gramática comparativa de línguas semíticas sobre o estudo do hebráico no século XIX. Pela comparação entre as obras de Genesius (1817) e Bauer & Leander (1918), o autor pontua alguns aspectos dessa influência no século XIX, e as mudanças de perspectiva ocorridas sob a influência da linguística do século XIX.Este artigo analisa a influência da gramática comparativa de línguas semíticas sobre o estudo do hebráico no século XIX. Pela comparação entre as obras de Genesius (1817) e Bauer & Leander (1918), o autor pontua alguns aspectos dessa influência no século XIX, e as mudanças de perspectiva ocorridas sob a influência da linguística do século XIX
I Wanna Hold Your Hand: Touch, Intimacy and Equality in Christopher Marlowe's "Hero and Leander" and George Chapman's "Continuation"
abstract: This thesis examines Christopher Marlowe's poem Hero and Leander and George Chapman's Continuation thereof through a theoretical lens that includes theories of intimacy, sexuality and touch taken from Lee Edelman, Daniel Gil, James Bromley, Katherine Rowe and others. Hands are seen as the privileged organ of touch as well as synecdoche for human agency. Because it is all too often an unexamined sense, the theory of touch is dealt with in detail. The analysis of hands and touch leads to a discussion of how Marlowe's writing creates a picture of sexual intimacy that goes against traditional institutions and resists the traditional role of the couple in society. Marlowe's poem favors an equal, companionate intimacy that does not engage in traditional structures, while Chapman's Continuation to Marlowe's work serves to reaffirm the transgressive nature of Marlowe's poem by reasserting traditional social institutions surrounding the couple. Viewing the two pieces of literature together further supports the conclusion that Marlowe's work is transgressive because of how conservative Chapman's reaction to Hero and Leander is.Dissertation/ThesisM.A. English 201
The curious and neglected soft-bodied meiofauna: Rouphozoa (Gastrotricha and Platyhelminthes)
Gastrotricha and Platyhelminthes form a clade called Rouphozoa. Representatives of both taxa are main components of meiofaunal communities, but their role in the trophic ecology of marine and freshwater communities is not sufficiently studied. Traditional collection methods for meiofauna are optimized for Ecdysozoa, and include the use of fixatives or flotation techniques that are unsuitable for the preservation and identification of soft-bodied meiofauna. As a result, rouphozoans are usually underestimated in conventional biodiversity surveys and ecological studies. Here, we give an updated outline of their diversity and taxonomy, with some phylogenetic considerations. We describe successfully tested techniques for their recovery and study, and emphasize current knowledge on the ecology, distribution, and dispersal of freshwater gastrotrichs and microturbellarians. We also discuss the opportunities and pitfalls of (meta)barcoding studies as a means of overcoming the taxonomic impediment. Finally, we discuss the importance of rouphozoans in aquatic ecosystems and provide future research directions to fill in crucial gaps in the biology of these organisms needed for understanding their basic role in the ecology of benthos and their place in the trophic networks linking micro-, meio-, and macrofauna of freshwater ecosystems.Julian P.S. Smith III was supported bygrant P20GM103499 (SC INBRE) from the National Institute of
General Medical Sciences, National Institutes of Health; Niels
Van Steenkiste and Brian Leander were supported by grants
from the National Science and Engineering Research Council of
Canada (2019-03986) and the Hakai Institute; Maria Balsamo
and Loretta Guidi were supported by Scientific Research grants
from the Italian Ministry of University (MIUR, 2019). The
authors are grateful to Dr. Rick Hochberg for the free and open
sharing of his ideas concerning feeding guilds in gastrotrichs,
and to Dr. Seth Tyler for pointing us to historical literature on
microturbellaria as parasites and hosts.Balsamo, M (corresponding author), Univ Urbino, Dept Biomol Sci, Urbino, Italy.
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A comparative study of the certification requirements for teachers in fifteen southern states, 1940
Placebo effects on nausea and motion sickness are resistant to experimentally-induced stress
Abstract Nausea often occurs in stressful situations, such as chemotherapy or surgery. Clinically relevant placebo effects in nausea have been demonstrated, but it remains unclear whether stress has an impact on these effects. The aim of this experimental study was to investigate the interplay between acute stress and placebo effects in nausea. 80 healthy female volunteers susceptible to motion sickness were randomly assigned to either the Maastricht Acute Stress Test or a non-stress control condition, and to either placebo treatment or no treatment. Nausea was induced by a virtual vection drum and behavioral, psychophysiological as well as humoral parameters were repeatedly assessed. Manipulation checks confirmed increased cortisol levels and negative emotions in the stressed groups. In the non-stressed groups, the placebo intervention improved nausea, symptoms of motion sickness, and gastric myoelectrical activity (normo-to-tachy (NTT) ratio). In the stressed groups, the beneficial effects of the placebo intervention on nausea and motion sickness remained unchanged, whereas no improvement of the gastric NTT ratio was observed. Results suggest that placebo effects on symptoms of nausea and motion sickness are resistant to experimentally-induced stress. Stress most likely interfered with the validity of the gastric NTT ratio to measure nausea and thus the gastric placebo effect
The concealed presence of the other: the imprint of European literature on the production of the first Greek novel Leander
“Some people could accuse us of having copied from Foscolo’s Jacopo Ortis or from Goethe’s Werther, but, if you read these books, they witness in our favour” writes Panayotis Soutsos in the introduction of Leander, defending his novel. Nevertheless, we find passages where the author closely imitates those texts, endorsing the idea of a creative translation. This is however a provocation; he throws caution to the wind, challenging the reader to reveal his deceit and thereby match his own knowledge. Though Soutsos’s writing points to some specific models, he conceals his greatest influence, French literature. The more extended passages, adapted and embedded in his text, come from Lamartine’s poetry and Chateaubriand’s novels. Is this a voluntary or a subconscious failure to quote his source? To what extent can attentive reading affect the creative procedure? These questions lead us to the problem: how do Modern Greeks position themselves in respect to Europe? The Greek Enlightenment claims Ancient Greek culture back from Europe, integrating it into the Greek tradition. As Koraes points out, now is the time for Europeans to pay their debt, by transposing the culture they received to the Modern Greeks. In a way, the text reflects these ideas by appropriating discourse. Europe is the Other, cherished and detested. It is therefore present in absentia, haunting creation, emerging throughout the Greek text
Zimmerman - Leander M. Zimmerman
A.B.; A.M., 1887; Phi Beta Kappa; Philomathaean. Entered Preparatory, 1878. Grad. Gettysburg Seminary, 1887; D.D., Susquehanna U., 1901. Born Aug. 29, 1860, or August 22, 1861, Manchester, Md. Parents, Henry and Leah. Brother of J.Z., class of 1873. Lutheran clergyman: Baltimore, Md., 1887-1925; pastor-emeritus, Christ Church, Baltimore, Md., 1925- . Member, Home Miss. Bd., 1899-1908; pres. of Deaconess Bd.; past pres. of Md. Synod; director, Gettysburg Seminary, 1909- ; past pres., Baltimore Min. Assoc. Author: Paths That Cross; Yvonne; Sparks; Cordelia; Dot; Echoes from Battlefield; For Love's Sake; Reminiscences; The Gospel Minister; and many booklets on social and religious subjects. Address: Burlington Hotel, Washington D.C
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