1,370 research outputs found
19.1 A 300MHz-BW, 27-to-38dBm In-Band OIP3 sub-7GHz Receiver for 5G Local Area Base Station Applications
No full textRecently, the so-called sub-6GHz band of the 5G new radio (NR) has been extended to 7.125GHz to address the relentless customer demand for higher data-rate communication. This demands a new design approach for the local area base-station (LA-BS) receivers (RXs) to cover a wide operating frequency range of 0.41 to 7.125GHz. Moreover, for NR bands above 3GHz, the maximum RF bandwidth (BW) is as high as 400MHz, in which a -35dBm modulated in-band (IB) blocker can be present. These impose stringent BW and IB linearity requirements for the baseband amplifiers in the LA-BS receivers. In addition to IB interferences, a -15dBm continuous-wave (CW) out-of-band (OOB) close-in blocker can also be present at 60MHz offset frequency from the passband edges, thus demanding a highly selective RX. Finally, the blocker 1dB compression point (B1textdB) becomes a key parameter for local area co-location applications in which the power of the far-out OOB blocker can be as large as -4dBm.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic
A 4 GHz Continuous-Time ΔΣ ADC With 70dB DR and -74dBFS THD in 125MHz BW
No full textA 4 GHz third-order continuous-time ΔΣ ADC is presented with a loop filter topology that absorbs the pole caused by the input capacitance of its 4-bit quantizer and also compensates for the excess delay caused by the quantizer's latency. The ADC was implemented in 45 nm-LP CMOS and achieves 70 dB DR and -74 dBFS THD in a 125 MHz BW, while dissipating 260 mW from 1.1/1.8 V supply. The ADC occupies 0.9 mm 2 including the modulator, clock circuitry and decimation filter.Accepted Author ManuscriptElectronic Instrumentatio
A 280μW dynamic-zoom ADC with 120dB DR and 118dB SNDR in 1kHz BW
No full textMicro-power ADCs with high linearity and dynamic range (DR) are required in several applications, such as smart sensors, biomedical imaging, and portable instrumentation. Since the signals of interest are then often small (tens of μν) and slow (<1kHz BW), such ADCs should also exhibit low offset and flicker noise. Noise-shaping SAR [1] and incremental ADCs [2] have been proposed for such applications, but their DR is limited to about 100dB. Although the ΔΣ modulator (ΔΣM) proposed in [3] achieves 136dB DR, it is at the expense of high power consumption (12.7mW). The incremental zoom ADC proposed in [4] combines a coarse SAR ADC and a fine ΔΣ ADC to efficiently achieve 119.8dB DR, but is limited to DC signals. The dynamic zoom ADC in [5] solves this problem, but requires external filtering to cope with out-of-band interference. This paper describes an interferer-robust dynamic zoom ADC that consumes 280μW while achieving 120.3dB DR and 118.1dB SNDR in 1kHz BW, resulting in a Schreier FoM of 185.8dB. It also achieves a maximum offset of 30μν and a 1/f corner of 7Hz. These advances are achieved by the combination of dynamic error-correction techniques, an asynchronous SAR ADC and a fully differential inverter-based ΔΣ ADC.Session 14.5 Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic Instrumentation(OLD)Applied Quantum ArchitecturesMicroelectronic
Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary exacerbation onset
No full textAcute periods of pulmonary exacerbation are the single most important cause of morbidity in cystic fibrosis patients, and may be associated with a loss of lung function. Intervening prior to the onset of a substantially increased inflammatory response may limit the associated damage to the airways. While a number of biomarker assays based on inflammatory markers have been developed, providing useful and important measures of disease during these periods, such factors are typically only elevated once the process of exacerbation has been initiated. Identifying biomarkers that can predict the onset of pulmonary exacerbation at an early stage would provide an opportunity to intervene before the establishment of a substantial immune response, with major implications for the advancement of cystic fibrosis care. The precise triggers of pulmonary exacerbation remain to be determined; however, the majority of models relate to the activity of microbes present in the patient's lower airways of cystic fibrosis. Advances in diagnostic microbiology now allow for the examination of these complex systems at a level likely to identify factors on which biomarker assays can be based. In this article, we discuss key considerations in the design and testing of assays that could predict pulmonary exacerbations
Apsidal motion elements of three eccentric eclipsing binaries: V397 Cep, V493 Car and BW Aqr
No full textThe apsidal motion analysis of the eccentric eclipsing binaries: V397 Cep, V493 Car and BW Aqr have been presented. The method described by Lacy (1992) [Lacy, C.H S.. 1992. AJ 104, 2213] has been used for the apsidal motion analysis. The apsidal motion periods have been found to be 174.2 +/- 1.4, 277.3 +/- 21.3 and 7195 +/- 174 years for V397 Cep, V493 Car and BW Aqr, respectively. (C) 2009 Elsevier B.V. All rights reserved.Research Foundation of the Canakkale Onsekiz Mart UniversityThe author acknowledges the partial support by Research Foundation of the Canakkale Onsekiz Mart University
Migration of influenza virus-specific polypeptides from cytoplasm to nucleus of infected cells.
No full textAbstract
Previous studies have shown that various influenzavirus polypeptides are associated with the infected cell nucleus. To clarify the pattern of distribution of influenzavirus-specific polypeptides between nucleus and cytoplasm in infected cells and to gain further information concerning functions of influenzavirus replication occurring in the host cell nucleus, we have used high-resolution pulse-labeling experiments and detailed ultrastructural examination of purified preparations of nuclei. In addition to NP and NS1, both P1 and P2 associate preferentially with the nucleus, while P3 and NS2 remain in the cytoplasm. The viral M protein is seen in nuclear fractions only when these fractions are significantly contaminated by plasma membrane. The preferential association of P1 and P2 with nuclei suggests that these proteins, in conjunction with NP and NS1, are involved in specific functions which may include viral transcription, while P3 and NS2 are involved in a distinct role in the cytoplasm.
Author to whom reprint requests should be sent.1
Present address: The Rockefeller University, 1230 York Avenue, New York, N. Y. 10021.
2
Permanent address: Istituto di Microbiologia, Universita Degli Studi di Parma, Italy.
Copyright © 1981 Published by Elsevier Inc.
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"g conti migration nuclear cytoplasmic influenza virus "
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A 3.2mW SAR-assisted CTΔΣ ADC with 77.5dB SNDR and 40MHz BW in 28nm CMOS
No full text\u3cp\u3eThis paper presents a SAR-assisted Continuous-time Delta-Sigma (CT Δ Σ ) ADC, which combines the energy efficiency of SAR ADCs with the relaxed driving requirements of CT Δ Σ ADCs, as well as similar anti-alias filtering. When clocked at 2.4GHz, the ADC achieves 77.5dB SNDR in 40MHz BW. It consumes 3.2mW, resulting in a state-of-the-art Walden FoM of 6.5fJ/cs and a Schreier FOM of 178.5dB.\u3c/p\u3
A 25A Hybrid Magnetic Current Sensor with 64mA Resolution, 1.8MHz Bandwidth, and a Gain Drift Compensation Scheme
No full textMagnetic current sensors are used in switched-mode power supplies and motor drivers, where both galvanic isolation and wide bandwidth (BW) are desired. In CMOS, Hall-effect sensors are widely used, but their resistance results in a fundamental trade-off between BW and resolution. Coils have a differentiating characteristic and so can achieve much wider BW and resolution, but cannot sense DC.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
Concerns about data integrity across 263 papers by one author
No full textOBJECTIVE: Comprehensive investigation of published work by authors suspected of academic misconduct can reveal further concerns. We aimed to test for data integrity concerns in papers published by an author with eight retracted articles. STUDY DESIGN: We investigated the integrity of all papers reporting on prospective clinical studies by this author. We assessed the feasibility of study methods, baseline characteristics, and outcomes. We plotted the author's clinical research activity over time. We conducted pairwise comparisons of text, tables, and figures to identify duplicate publications, and checked for consistency between conference abstracts, interim analyses, trial registrations, and final papers. Where indicated, we recalculated p-values from the reported summary statistics. RESULTS: We identified 263 papers claiming to have enrolled 74,667 participants between January 2009 and July 2022, 190 (72 %) of which reported on studies that recruited from the Assiut Women's Health Hospital in Assiut, Egypt. The number of active studies per month was greatest between 2016 and 2019, with 88 ongoing studies in May 2017. We found evidence of data integrity concerns in 130 (49 %) papers, 43 (33 %) of which contained concerns sufficient to suggest that they could not be based on data reliably collected from human participants. CONCLUSION: Our investigation finds evidence of widespread integrity concerns in the collected work of one author. We recommend that the involved journals collaborate in a formal investigation
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