244 research outputs found
Comparison of foot pain and foot care among rheumatoid arthritis patients taking and not taking anti-TNF? therapy: an epidemiological study
No full textEpidemiological studies report foot pain affects more than 90% of people with rheumatoid arthritis (RA). Most data about foot involvement in RA were collected prior to the availability of novel treatments such as biologics. The objective of this study is to compare the prevalence of foot symptoms, frequency of foot examination, and access to foot care services among RA patients currently treated with anti-TNF? to those not receiving biologics. This study is a cross-sectional epidemiological study: a 28-item self-administered questionnaire was posted to 1,040 people with RA throughout the UK. Overall, 585 (55%) useable replies were received, and 120 (20.5%) respondents were currently taking anti-TNF? medication. Prevalence of current foot pain was 99% among the biologics group compared with 76% not treated with biologics. Stiffness, swelling, and numbness in the feet were all significantly more common in the anti-TNF? group (P < 0.05). Most respondents (90%) taking biologics discussed their foot pain with their rheumatologist, but only 70% were receiving podiatry (compared to 78% not taking anti-TNF?). Subjects reported that their feet were examined significantly less frequently (P < 0.001) than their hands. Foot complaints are common in this group, and allied health professions could enhance rheumatological care by undertaking foot assessment
Identifying patient-reported outcomes in rheumatoid arthritis: the impact of foot symptoms on self-perceived quality of life
No full textBACKGROUND: The importance of patient-reported outcome measures in healthcare is increasingly recognized but these need to be patient generated. Given that foot symptoms are very common in rheumatoid arthritis (RA), we chose a patient-centred model with which to investigate the patients' perspective on how their foot symptoms affected them as individuals and impacted on their self-perceived quality of life, rather than using the traditional approaches of clinical examination (e.g. prevalence of deformities) or radiological assessments.METHODS: A 33-item self-administered postal questionnaire was sent to all people with RA attending outpatient clinics in three hospitals over the course of one month (n=390). The questionnaire used both quantitative and qualitative approaches to enquire about the nature and extent of foot complaints and how respondents believed this affected their quality of life.RESULTS: In total, 190 usable replies were received (49%). Nearly all respondents (n=177; 93.2%) reported that their quality of life was adversely affected by their foot complaint(s), with over half describing their quality of life as being badly or very badly affected. When asked to rate how severely foot complaints affected their quality of life using a 10 cm visual analogue scale, the mean score was 5.36 (range 0-10 ± SD 3), indicating that foot complaints have a moderate-to-severe effect on quality of life. Those aspects of daily living most significantly affected were: the ability to walk and the ability to wear a variety of shoes.CONCLUSION: This study demonstrated that people with RA focus on different aspects of the impact of their disease to doctors. Rather than foot deformity or ulceration, disease activity score or health assessment questionnaire score, patients were easily able to pinpoint the key negativities of living with RA in their feet and indicated choice of footwear and ability to walk as crucial. This study and similar ones are key to identifying appropriate patient-reported outcome measures.<br/
Social and political dynamics of flood risk, recovery and response. A report of the findings of the Winter Floods Project
No full textThis report should be cited as: Butler, C., Walker-Springett, K., Adger, W. N., Evans, L. & O’Neill, S. 2016.
Social and political dynamics of flood risk, recovery and response, The University of Exeter, Exeter.No abstractWe acknowledge funding from the UK Economic and Social Research Council [Grant: ES/M006867/1]. We
further acknowledge funding from the National Institute for Health Research Health Protection Research Unit
(NIHR HPRU) in Environmental Change and Health at the London School of Hygiene and Tropical Medicine
in partnership with Public Health England (PHE), and in collaboration with the University of Exeter, University
College London, and the Met Office
Breakfast on a Dragon’s Tail: and Other Book Bites by M. Springett
No full textSpringett, Martin. Breakfast on a Dragon’s Tail: and Other Book Bites. Markham, ON: Fitzhenry and Whiteside, 2011. Print. This unusual volume by award-winning illustrator/author Martin Springett takes the “choose your own ending” idea to a whole new level by not providing an ending at all. In fact the whole book is made up of thirteen beginnings of stories, each accompanied by a full-page illustration, which might have served as a book cover. The book is designed to promote creative activities. Springett tells children that each story “should have a beginning, a middle and an end” and that he has provided the beginning. He encourages children to finish the stories in any way they like, through creative endeavors ranging from poetry to a “chalk drawing on the sidewalk”. Children are also encouraged to post their stories to publisher Fitzhenry and Whiteside’s website, where “teachers and parents will also find useful information and classroom activities”. Springett’s art-work depicts the fantastic in each story. The first image, accompanying Breakfast on a Dragon’s Tail, is bordered by patterns that recall a medieval illuminated manuscript. In the same vein, the letter “O” which begins the story is embellished with a dragon curled around it. The others are more cartoon-like. Springett’s writing is very good . His story beginnings are engaging. In the Twelve Dancing Crocodiles the reader finds out that a magician and twelve dancing princesses have disappeared. Are they the twelve dancing crocodiles? They are if you want them to be. In The Nattering Tree, people sit under a tree and listen as the tree talks to itself. There are also lots of good one-line jokes in the story beginnings. In the Dithering Ducks of Deptford, one of the ducks says, “Never listen to a gnome! They are born naughty!” Another story, which has nothing to do with computers, is called Chip and Pin. In Dracula and Son, Springett irreverently refers to the characters as “Papa Drac” and “Drac Junior”. It would have been entertaining to read Springett’s versions of the endings. In fact, some children may be put off by the fact that they have to think up their own endings and entertain themselves. Because of that, this book will probably work best in a structured environment, where children have a reason to stay on track and complete the stories. Overall this book is an interesting concept, that is probably best suited to the classroom environment, so it is recommended with that reservation.Recommendation: 3 stars out of 4 Reviewer: Sandy Campbell Sandy is a Health Sciences Librarian at the University of Alberta, who has written hundreds of book reviews across many disciplines. Sandy thinks that sharing books with children is one of the greatest gifts anyone can give
Birth prevalence and survival of exomphalos in England and Wales: 2005 to 2011
No full textBackgroundExomphalos occurs in 2.2 per 10,000 births with 76% of these babies surviving to discharge. The aim of this study was to determine the birth prevalence and survival of babies with this anomaly in England and Wales.MethodsSix BINOCAR regional congenital anomaly registers in England and Wales (covering 36% of births) between 2005 and 2011 provided cases for this study. Cases included live births, stillbirths (24+ weeks' gestation), late miscarriages (20–23 weeks' gestation), and terminations of pregnancy with fetal anomaly.ResultsThe overall birth prevalence was 3.8 (95% confidence interval [CI]: 3.6–4.0) per 10,000 births; 1.4 (1.2–1.6) for isolated cases, 1.2 (1.1–1.4) for cases with multiple anomalies, and 1.2 (1.1–1.4) for cases with chromosomal anomalies. The live birth prevalence was 0.8 (0.7–0.9), 0.5 (0.4–0.6), and 0.1 (0.0–0.1) per 10,000 live births, respectively. Edwards syndrome, congenital heart defects, and nervous system anomalies were the most common anomalies associated with exomphalos. A prenatal diagnosis was made in 83% of isolated, 95% of multiple, and 99% of chromosomal cases. Fifty-five percent of isolated and multiple cases were live born, whereas 85% of cases with chromosomal anomalies resulted in a termination of pregnancy with fetal anomaly. The 1-year survival of live born babies with an isolated exomphalos was 92% compared with 81% in cases with multiple anomalies and 27% in cases with chromosomal anomalies (p?<?0.001).ConclusionWe report a higher birth prevalence than has previously been reported. The proportion of infants surviving with exomphalos remained unchanged over the time period<br/
Experimental hypercholesterolemia induces apoptosis in the aortic valve
No full textAortic valve disease is presently the number one indication for valve replacement in the United States, yet its molecular mechanisms remain unknown. As apoptosis (programmed cell death) occurs in degenerative disease states, it was postulated that experimental hypercholesterolemia is associated with apoptosis in rabbit aortic valves
Ovalturning
No full textOvalturning is an ancient woodturning art, recently revived by new ovalturning lathes designed and tested by the author.
These lathe, their accessories and their usage and application are described in detail. The fundaments are kinematical mechanism analysis and the ellipse geometry.
A gallery of oval turned items for usage shows partially the variety of ovalturning application.
At the end is given a list of relevant literature, videos and addresses in the internet and of ovalturning practioners and schools.
Second editio
Team
No full textThe Waratah football team 1931-32, runners up in the finals. Back row L-R J Mair(Muir?); R Edwards; R Lowe; D Weller; W Hoskings; P Graham; J Henderson; L Irwin; W Eacott; W Harmer; D Caldwell; W Leaver; I Bell; K Springett Front row L-R L Lampe; J Watts; P Binet; G Auso; N JarvieYoung, Mayse.Date:193
Accessibility of interactive television for users with low vision: learning from the web.
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