1,040 research outputs found

    BiTE the Multiple Myeloma: Racing to Alter Patient Cells to Kill Cancer

    No full text
    BiTE the Multiple Myeloma: Racing to Alter Patient Cells to Kill Cancer, Drs. Niraj Neupane, Internal Medicine, Sanjana Kashinath, Hematology Oncology, Saad Jamshed, Division Head, Hematology Oncology at Rochester General Hospital Objectives: Newer therapies in managing multiple myeloma and their toxicities with case based learnin

    The Cooking Solutions for Rural Livelihood: A Study of Sundarbazar Municipality

    No full text
    Electric cooking systems have been promoted in Sundarbazar Municipality of Lamjung district as an alternative to liquefied petroleum gas (LPG) for cooking purposes. This study aims to assess the effectiveness of electric cooktops on rural livelihood. The study was conducted using a sample survey with a simple random sampling technique. The data was gathered through household surveys, focused group discussions, and field observations. The major source of data was a sample survey. The study found that local people experienced induction cooktops as a time-saving, fast processing, and economically viable option for cooking purposes. The study also found that electric cooking solutions may be a good alternative to LPG in both urban and rural areas, as Nepal will produce excess electricity in the near future. The study suggests that innovation for electric cooking has the possibility of enhancing better livelihood in rural contexts. This study concludes that electric cooking solutions have positive impacts on rural livelihoods. The promotion of electric cooking among households can reduce the consumption of imported LPG. The study suggests that local governments should play an active and major role in advocating for electric cooking, providing training, and different forms of incentives such as distributing prizes. The study also suggests that capacity-building programs for users.How to cite this article: Neupane, B. K., (2023). The Cooking Solutions for Rural Livelihood: A Study of Sundarbazar Municipality. GS Spark: Journal of Applied Academic Discourse. 1(1), 17-26. https://doi.org/10.5281/zenodo.837175

    Policy and Strategy for Increasing Income and Food Security through Improved Crop Management of Chickpea in Rice Fallows in Asia:Summary of a NARC-ICRISAT-NRI Workshop 17-18 November 2004, Kathmandu, Nepal

    No full text
    This book consists of the following papers: Welcome address (Maske, S.L.); welcome address from ICRISAT: legumes and cereals in development and the need for effective policy change to help alleviate poverty in South Asia (Keatinge, J.D.H.); welcome address from NRI (Stevenson, P.C.); keynote address from NARC: approaches in improving pulses production in Nepal (Pathik, D.S.); keynote address from DOA: Improving production of pulses through extension programs: constraints and opportunities (Shrestha, S.S.); integrated crop management of chickpea in Nepal: past, present and future (Pande,S.; Neupane, R.K.; Stevenson, P.C.; Grazywacz,D.; Bourai,V.A.; Rao, J.N.; Kishore, G.K.); opening remarks (Kaini, B.R.); opening remarks (Chaudhary, U.); remarks by the Chief Guest (Dahal, H.N.); chairperson's remarks (Upadhyaya, H.K.); vote of thanks (Pande, S.); session 1: introductory papers: prospects of chickpea in rice-based cropping systems in Bangladesh (Uddin, M.J.; Ali, M.O.; Rahman, M.M.); Lessons learnt from participatory dissemination and uptake pathways of IPM of chickpea and lentils in Bangladesh ( Bakr, M.A.; Afzal, M.A.; Aktar, M.S.); lessons learned from farmers' participatory BGM management in India (Tripathi, H.S.); promotion of rainfed rabi cropping in rice fallows of eastern India, Bangladesh, and Nepal: an overview (Rao, J.V.D.K.; Harris, K.D.; Joshi, K.D.; Khanal, N.; Johansen, C.; Musa, A.M.); session II: scaling-up and Uptake Pathways: lessons learned from scaling up participatory variety selection: LI-BIRD experiences (Devkota, K.P.; Gyawali, S.; Tripathi, M.P.; Joshi, K.D.; Witcombe, J.R.); scaling-up of participatory variety selection in wheat in South Asia: The CIMMYT-NARS experience (Ortiz-Ferrara, G.; Joshi, A.K.; Mudwari, A.; Bhatta, M.R.; Souffian, S.; Witcombe, J.R.); the scaling-up process and outputs of participatory crop improvement in Nepal: adoption and impact (Joshi, K.D.; Devkota, K.P.; Gyawali, S.; Tripathi, M.P.; Witcombe, J.R.); experiences of scaling-up: Nepal Agricultural Research Council (Ghimire, Y.N.; Pokharel,T.P.; Khadka, R.; and Gauchan, D.); the role of APPSP: Lessons learned (Mainali, P.); session III: Commodity Seed Production and Farmers' perceptions: seed quality control mechanisms in Nepal (Lal, K.K.); chickpea cultivation: Farmers'perceptions (Aryal, B.K.); chickpea cultivation: farmers'perceptions (Shrestha, K.K.); chickpea cultivation: Farmers'perceptions (Adhikary, S.); chickpea cultivation: Farmers'perceptions (Khatri, B.); session IV: DFID-funded and Related Projects: on-farm IPM of chickpea in Nepal: dissemination, adoption and promotion, 1997-2005 (Neupane, R.K.; Joshi, M.; Pande, S.; Yadav, N.K.); the adoption of ICM technologies by poor farmers in Nepal (Stevenson, P.C.; Pande, S.; Neupane, R.K.; Chaudhary, R.N.; Bourai, V.A.; Rao, J.N.; Grzywacz, D.); alternative pest control approaches: NPV for pod borer control and its uptake in Nepal (Grzywacz, D.; Pande, S.; Khanal, N.P.; Maharjan, R.); Farmers' empowerment, soil enrichment and wealth generation through chickpea-IPM in Nepal (Bourai, V.A.; Pande, S.; Neupane, R.K.; Stevenson, P.C.); rabi cropping and promoting winter legumes in rice fallows in Nepal (Khanal, N.; Joshi, K.D.; Harris, D.); bridging the gap: Role, responsibilities and approaches to scaling-up IPM of chickpea in Nepal (Khanal, N.P. and Khanal, N.); developing positive outcomes from livelihood studies (Pound, B.); Upscaling zero tillage in rice fallow lands of the Indo-Gangetic Plains: Some experiences (Gupta, R.K.; Pande, S.); role and responsibility of the media in promoting cost-effective farmer-friendly agricultural technologies (Basnet, B.M.); agriculture and mass media in Nepal: Link or missing link? (Lamsal, Y.); country-wide extension of integrated crop management of chickpea in Nepal: lessons learned and future approaches (Stevenson, P.C.; Pande, S.; Pound, B.)

    Unusual magnetic and transport properties in HoMn6Sn6 kagome magnet

    No full text
    With intricate lattice structures, kagome materials are an excellent platform to study various fascinating topological quantum states. In particular, kagome materials, revealing large responses to external stimuli such as pressure or magnetic field, are subject to special investigation. Here we study the kagome-net HoMn6Sn6 magnet that undergoes paramagnetic to ferrimagnetic transition (below 376 K) and reveals spin-reorientation transition below 200 K. In this compound, we observe the topological Hall effect and substantial contribution of anomalous Hall effect above 100 K. We unveil the pressure effects on magnetic ordering at a low magnetic field from the pressure tunable magnetization measurement. By utilizing high-resolution angle-resolved photoemission spectroscopy, Dirac-like dispersion at the high-symmetry point K is revealed in the vicinity of the Fermi level, which is well supported by the first-principles calculations. Our investigation will pave the way to understanding the magnetotransport and electronic properties of various rare-earth-based kagome magnets

    Anisotropically large anomalous and topological Hall effect in a kagome magnet

    No full text
    Recently, kagome materials have become an engrossing platform to study the interplay among symmetry, magnetism, topology, and electron correlation. The latest works on RMn6Sn6 (R = rare-earth metal) compounds have illustrated that this family could be intriguing to investigate various physical phenomena due to large spin-orbit coupling and strong magnetic ordering. However, combined transport and spectroscopic studies in RMn6Sn6 materials are still limited. Here, we report magnetic, magnetotransport, and angle-resolved photoemission spectroscopy measurements of a kagome magnet ErMn6Sn6 that undergoes antiferromagnetic (TN = 345 K) to ferrimagnetic (TC = 68 K) phase transitions in the presence of a field. We observe large anomalous and topological Hall effects serving as transport signatures of the nontrivial Berry curvature. The isothermal magnetization exhibits strong anisotropic nature and the topological Hall effect of the compound depends on the critical field of metamagnetic transition. Our spectroscopic results complemented by theoretical calculations show the multiorbital kagome fermiology. This Letter provides new insight into the tunability and interplay of topology and magnetism in a kagome magnet.</p

    Invariant measures of piecewise concave dynamical systems via maximum entropy optimization method

    No full text
    Piecewise Concave Dynamical System (PCDS) has its wide application in various science fields. Many real-world problems can be modeled into mathematical models via PCDS. First, we let T: [0,1] → [0,1] be a piecewise concave transformation/maps (PCDS) and study the existence of absolutely continuous invariant measures. Then, we present a maximum entropy optimization method for approximating densities of Piecewise Concave Maps. A numerical example will be presented to compare the approximate densities of Piecewise Concave Maps using the maximum entropy method and the actual densities of the Piecewise Concave Maps

    Solvent-Assisted Lipid Bilayer Formation on Au Surfaces: Effect of Lipid Concentration on Solid-Supported Membrane Formation

    No full text
    Solvent-assisted lipid bilayer (SALB) formation is emerged as a versatile approach in forming supported lipid membranes (SLBs) on metal surfaces, interesting platforms for transducing a biological signal to an electrical readout where vesicle rupture is not straightforward. Herein, the effect of the lipid concentration in the organic solvent, a key parameter controlling SALB, is addressed in the low and high concentration limits of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine lipid on a Au surface. Quartz crystal microbalance with dissipation (QCM-D) responses are correlated with atomic force microscopy (AFM) topographic and nanomechanical measurements. Upon SALB completion at both concentrations, QCM-D and AFM topographical characterization suggest the formation of thin, although incomplete, lipid layers at the Au–liquid interface, with frequency and dissipation plateau values departing from well-established homogeneous SLB responses. Nanomechanical analysis reveals the presence of mostly monolayers at low concentration due to lack of lipid material, while at high concentration excess of lipid material leads to the coexistence of diverse structures. Their formation stems from the SALB formation mechanism, based on lyotropic transformations upon solvent exchange, which differs from customarily vesicle rupture. Such mechanism leads to peculiar two-step features in approach force curves on SLBs pointing toward a decoupling in bilayer leaflets when supported.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Excited state electronic structure, excitation energy transfer, and charge separation dynamics in various natural and artificial photosynthetic systems containing zinc and magnesium chlorins

    No full text
    Doctor of PhilosophyDepartment of ChemistryRyszard J. JankowiakThis dissertation reports the low temperature frequency domain spectroscopic study of three different natural pigment protein complexes and one artificial antenna system. The main focus of this work is to better understand electronic structure, excitation energy transfer (EET), and electron transfer (ET) dynamics in these systems that could have impact on achieving higher efficiency in future artificial solar cells. In the first part of this dissertation, electronic structure and EET pathways in isolated intact CP43 prime protein complex, which is isolated from Cyanobacterium synechocystis PCC 6803 grown under iron stressed conditions, are investigated using low-temperature absorption, fluorescence, fluorescence excitation, and hole-burning (HB) spectroscopies. This work suggests that, in analogy to the CP43 complex of PSII core, CP43 prime possesses two quasi-degenerate low energy states, A prime and B prime. The various low-temperature optical spectra are fitted considering an uncorrelated EET model. This work suggests that for optimal energy transfer from CP43 prime to PSI, the A prime and B prime state chlorophylls belonging to each CP43 prime should face towards the PSI core. The second part of dissertation reports the photochemical HB study on novel Zinc bacterial reaction center (Zn-RC) from Rhodobacter sphaeroides and its β-mutant (Zn-β-RC). This study shows that ET in the two samples is similar; however, the quantum efficiency of charge separation in the mutant decreases by 60 %. This finding suggests that the coordination state of the HA site zinc bacteriochlorophyll does not tune the active branch ET. Simultaneous fits of various optical spectra using experimentally determined inhomogeneity provides more reliable electron phonon coupling parameters for the P870 state of both RC samples. In the last part of this dissertation, EET in a novel artificial antenna system (ethynyl linked chlorophyll trefoil, ChlT1) is investigated. EET time in ChlT1 is ~2 ps. ChlT1 in MTHF/ethanol glass forms four different types of aggregates, A1-A4. The EET time in A1 and A2 type aggregates slows down only by a factor of 5 and 7, respectively. This study suggests that ChlT1 and its aggregates can be used as efficient antenna systems in designing organic solar cells
    corecore