1,291 research outputs found
Effects of Activin A on the phenotypic properties of human periodontal ligament cells
No full textAbstract not availableHideki Sugii, Hidefumi Maeda, Atsushi Tomokiyo, Naohide Yamamoto, Naohisa Wada, Katsuaki Koori, Daigaku Hasegawa, Sayuri Hamano, Asuka Yuda, Satoshi Monnouchi, Akifumi Akamin
COUNTERPOINT CELLULITIS AND BACTERIA IN PERIPHERAL LYMPHEDEMA
No full textCounterpoint to the article: Peculiar Clinical Features of Cellulitis in Peripheral Lymphedema, by K. Suehiro, N. Morikage, K. Ueda, M. Samura, Y. Takeuchi, T. Nagase, T. Mizoguchi, K. Hamano
Line-depth Ratios in H-band Spectra to Determine Effective Temperatures of G- and K-type Giants and Supergiants
No full textThe stellar effective temperature is the fundamental parameter of stellar atmospheres. It characterizes the spectra and plays an essential role in chemical abundance analysis. Previous optical studies have shown that line-depth ratios (LDRs) are good indicators of the effective temperature. Essentially, the ratios of absorption lines with different excitation potentials can be used as temperature scales. The most important advantage of LDRs is their robustness against interstellar reddening and extinction. Furthermore, the scales are constructed and calibrated empirically by observables. Although this method is well-established for optical spectra, we require infrared high-resolution spectroscopy to access the most obscured stars in the Galactic disk and thereby understand the Milky Way’s structure and evolution in the innermost region. This study newly derives the temperature scales from the LDRs in infrared spectra. We explored LDRs in the high-resolution H-band spectra (1.4-1.8 μm) of well-known stars in the solar neighborhood obtained with Subaru/infrared camera and spectrograph. We found nine pairs of absorption lines whose LDRs allow us to determine the temperatures of G- and K-type giants/supergiants to an accuracy of ̃60 K. Checking the dependency of our scales on stellar parameters, we found that our developed temperature scales may slightly bias the estimates for low-metal stars, [Fe/H] < -0.3 dex
Vitamin K-dependent carboxylation of osteocalcin affects the efficacy of teriparatide (PTH1-34) for skeletal repair
No full textTeriparatide (PTH1-34) promotes skeletal repair and increases bone mass. Vitamin K is involved in bone mineralization as a coenzyme of gamma-carboxylase for Gla proteins, and therefore vitamin K insufficiency caused by malnutrition or therapeutic intake of the vitamin K antagonist warfarin could affect the efficacy of PTH1-34 therapy for bone repair. In the present study, we investigated whether vitamin K influences the efficacy of PTH1-34 therapy for bone repair in a rat osteotomy model. Female 12-week-old Sprague-Dawley rats were subjected to a closed midshaft osteotomy of the femur and randomized into four groups (n = 10 per group): vehicle, PTH1-34 (daily 30 mu g/kg/day subcutaneous injection) + solvent (orally, three times a week), PTh1-34 + warfarin (0.4 mg/kg/day orally, three times a week), and PTH1-34 + vitamin K-2 (menatetrenone, 30 mg/kg/day orally, three times a week). Serum gamma-carboxylated and uncarboxylated osteocalcin (Gla-OC and Glu-OC) levels and radiographic healing were monitored every 2 weeks. Skeletal repair was assessed by micro-computed tomography, mechanical testing, and histology at 8 weeks after surgery. PTH1-34 amplified the osteotomy-induced increase in Gla-OC and improved the mechanical properties as well as the volumetric bone mineral tissue density of the fracture callus. Concurrent use of warfarin decreased the response to PTH1-34 therapy in terms of mechanical recovery, probably by impairing mineralization due to the lack of Gla-OC. Although the effects of combination therapy with PTH1-34 and vitamin K-2 on bone repair did not significantly exceed those of PTH1-34 monotherapy in rats fed sufficient dietary vitamin K, postoperative Gla-OC levels were correlated with the mechanical properties of the osteotomized femur in PTH1-34-treated rats regardless of the use of warfarin or vitamin K-2. These findings suggest the importance of vitamin K dependent gamma-carboxylation of DC for realizing the full effects of PTH1-34 on skeletal repair. (C) 2014 Elsevier Inc. All rights reserved
GISEIGO DALAM KOMIK DETEKTIF CONAN VOLUME 5 KARYA AOYAMA GOUSHOU
No full textSkripsi ini merupakan kajian fonologi yang membahas giseigo pada komik Detektif Conan volume 5 karya Aoyama Goushou. Penelitian ini bertujuan mengetahui makna tentang giseigo?serta mengetahui keterkaitan giseigo dengan konsep fonologinya yang terdapat pada sumber?data. Teori yang digunakan adalah teori hubungan konsonan, vokal dan makna menurut Shoko Hamano. Setelah melakukan analisis, maka penulis menarik beberapa kesimpulan mengenai?giseigo yang terdapat dalam sumber data 21 buah giseigo yang dianalisis berdasarkan bunyi konsonan, vokal dan makna kata secara keseluruhan pembentuk Giseigo, Hamano membagi giseigo menjadi dua pola dasar yaitu KV (K= konsonan, V= vokal) dan KVKV. Tidak terdapat penyimpangan teori dalam analisis. Semua teori dapat diterapkan pada 21 data giseigo
Relationship between performance test and body composition/physical strength characteristic in sprint canoe and kayak paddlers
No full textSaki Hamano,1 Eisuke Ochi,2 Yosuke Tsuchiya,3 Erina Muramatsu,4 Kazuhiro Suzukawa,5 Shoji Igawa1 1Department of Sports Nutrition, Nippon Sport Science University, Yokohama, Kanagawa, 2Graduate School of Education, Okayama University, Okayama, 3Laboratory of Health and Sports Sciences, Meiji Gakuin University, Yokohama, Kanagawa, 4Department of Natural Sciences, Nippon Sport Science University, Setagaya, Tokyo, .5Laboratory of Preventive Medicine and Public Health, Nippon Sport Science University, Setagaya, Tokyo, Japan Objective: Canoe sprint is divided into canoe and kayak. The difference between the two competitions is in physical performance. The aim of the present study was to compare and investigate the relationship between physical characteristics and fitness between the two canoe sprint competitors. Methods: Subjects were 11 canoe paddlers (C) and 12 kayak paddlers (K). They underwent anthropometric characteristics, body composition and fitness tests, and 120 s all-out tests using a canoe and kayak ergometer. The unpaired t-test was used to test for significant differences between disciplines, while Pearson's correlation coefficient was used to examine the association between each measurement item and the performance test. Results: The age, height, body mass, body mass index, and total body fat were, C: 20.6±0.9 yr, 172.8±5.2 cm, 70.8±7.8 kg, 23.7±1.9, 14.4%±3.5%; and K: 19.7±1.2 yr, 172.8±5.3 cm, 69.5±7.8 kg, 23.2±2.1, 12.1%±3.6%, respectively. No significant differences were seen in any of the items for physical characteristics or fitness between C and K. A correlation analysis of performance tests and each measurement item revealed a positive correlation with low-speed isokinetic knee extension and flexion strength for C only (extension: r=0.761; flexion: r=0.784; P<0.01). In addition, performance tests were positively correlated with the circumference of arm (upper arm: r=0.876; forearm: r=0.820; P<0.01) and lower limb (thigh: r=0.781; calf: r=0.753; P<0.01) in C and with height (r=0.549, P<0.05), arm span (r=0.639, P<0.05), and leg length (r=0.621, P<0.01) in K. Conclusion: We suggest that the factors correlating with the performance test differ depending on the competitions. Keywords: canoe sprint, kayak, body composition, isokinetic strength, morpholog
Stochastic Transcription Elongation via Rule Based Modelling
No full textAbstractTranscription elongation is the mechanism by which RNA polymerase (RNAP) moves along template unzipped DNA and synthesizes a complementary single-stranded RNA. During the elongation, RNAP forms a stable transcription elongation complex (TEC) with the template DNA and the nascent RNA. The mechanism involves back-tracked and forward-tracked modes of TEC and the polymerisation and depolymerisation of RNA. To capture the stochasticity of the elongation, we describe the mechanism in terms of rule-based modelling through the TEC's local window frame of adjacent active sites. In this way, we can uniformly derive the variations of known kinetic pathways for various interaction combinations of TEC's active sites. From the compact interactions at local sites, we find abstracted rules for the elongation. As the semantic counterpart, we derive quasi-steady state approximations to the chemical master equations. The stochastic models are thermodynamically interpreted as the free energy distributions of agents with variant configurations
The 3He/4He ratio in a clay from the K-T boundary,Hokkaido, Japan
No full textP(論文)We measured the He content and the ^3He/^4He ratio of a K-T boundary clay from Hokkaido. If some meteoritic debris which escaped total melting or evaporation at the K-T event remains in the clay, it may be possible to observe some ^3He in it. However, we could determine only the upper limits of the ^3He/^4He ratois ( for a bulk sample) because of the small amount of ^3He. Three alternatives are considered to explain the result.departmental bulletin pape
Polarization reversal process in K<sub>2</sub>ZnCl<sub>4</sub>studied by the nematic liquid crystal technique
No full text(Table 5) Age control points of ODP Leg 127 sites
No full textSediment depth is given in mbsf. Paleomagnetic data are from Hamano et al. (1992), and biostratigraphic data are from Shipboard Scientific Party (1990) with the exception of the LO of Neodenticula kamtschatica (2.5 Ma control point) in Site 795 which is from Koizumi (1992)
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