6,745 research outputs found
Addressing Irregular Migration through Principled Programmatic Approaches: Examining the West Africa Route
No full textGanesh K. Seshan VIRTUAL RESEARCH SEMINAR Irregular Migration and Food Security: A View from West Africa Co-organized by IFPRI and World Food Programme (WFP) JUL 20, 2023 - 9:30 TO 11:00AM ED
Anuran assemblage and its trophic relations in rice-paddy fields of South India
No full textSeshadri, K. S., Allwin, Jesudasan, Seena, N. K., Ganesh, T. (2021): Anuran assemblage and its trophic relations in rice-paddy fields of South India. Journal of Natural History 54 (41-42): 2745-2762, DOI: 10.1080/00222933.2020.1867772, URL: http://dx.doi.org/10.1080/00222933.2020.186777
Proteins at charged interfaces
No full textThesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1993.Includes bibliographical references (p. 288-293).by Ganesh Venkataraman.Ph.D
K-Ras Binds Calmodulin-Related Centrin1 with Potential Implications for K-Ras Driven Cancer Cell Stemness
No full textpeer reviewedRecent data suggest that K-Ras4B (hereafter K-Ras) can drive cancer cell stemness via calmodulin (CaM)-dependent, non-canonical Wnt-signalling. Here we examined whether another Ca2+-binding protein, the CaM-related centrin1, binds to K-Ras and could mediate some K-Ras functions that were previously ascribed to CaM. While CaM and centrin1 appear to distinguish between peptides that were derived from their classical targets, they both bind to K-Ras in cells. Cellular BRET- and immunoprecipitation data suggest that CaM engages more with K-Ras than centrin1 and that the interaction with the C-terminal membrane anchor of K-Ras is sufficient for this. Surprisingly, binding of neither K-Ras nor its membrane anchor alone to CaM or centrin1 is sensitive to inhibition of prenylation. In support of an involvement of the G-domain of K-Ras in cellular complexes with these Ca2+-binding proteins, we find that oncogenic K-RasG12V displays increased engagement with both CaM and centrin1. This is abrogated by addition of the D38A effector-site mutation, suggesting that K-RasG12V is held together with CaM or centrin1 in complexes with effectors. When treated with CaM inhibitors, the BRET-interaction of K-RasG12V with centrin1 was also disrupted in the low micromolar range, comparable to that with CaM. While CaM predominates in regulating functional membrane anchorage of K-Ras, it has a very similar co-distribution with centrin1 on mitotic organelles. Given these results, a significant overlap of the CaM- and centrin1-dependent functions of K-Ras is suggested
Privately Answering Counting Queries with Generalized Gaussian Mechanisms
No full textWe give the first closed-form privacy guarantees for the Generalized Gaussian mechanism (the mechanism that adds noise x to a vector with probability proportional to exp(-(||x||_p/σ)^p) for some σ, p), in the setting of answering k counting (i.e. sensitivity-1) queries about a database with (ε, δ)-differential privacy (in particular, with low _∞-error). Just using Generalized Gaussian noise, we obtain a mechanism such that if the true answers to the queries are the vector d, the mechanism outputs answers d̃ with the _∞-error guarantee:
[||d̃ - d||_∞] = O(√{k log log k log(1/δ)}/ε).
This matches the error bound of [Steinke and Ullman, 2017], but using a much simpler mechanism. By composing this mechanism with the sparse vector mechanism (generalizing a technique of [Steinke and Ullman, 2017]), we obtain a mechanism improving the √{k log log k} dependence on k to √{k log log log k}, Our main technical contribution is showing that certain powers of Generalized Gaussians, which follow a Generalized Gamma distribution, are sub-gamma.
In subsequent work, the optimal _∞-error bound of O(√{k log (1/δ)}/ε) has been achieved by [Yuval Dagan and Gil Kur, 2020] and [Badih Ghazi et al., 2020] independently. However, the Generalized Gaussian mechanism has some qualitative advantages over the mechanisms used in these papers which may make it of interest to both practitioners and theoreticians, both in the setting of answering counting queries and more generally
Figure 3 in Anuran assemblage and its trophic relations in rice-paddy fields of South India
No full textFigure 3. Comparison of diet composition at both Order (Top, A) and taxonomically distinct units (Bottom, B). A non-metric multidimensional analysis using the Morisita index for abundance data is used to represent the similarity of diets. Red dots and line represent M. ornata and black X and line represent M. caperata.Published as part of Seshadri, K. S., Allwin, Jesudasan, Seena, N. K. & Ganesh, T., 2021, Anuran assemblage and its trophic relations in rice-paddy fields of South India, pp. 2745-2762 in Journal of Natural History 54 (41-42) on page 2754, DOI: 10.1080/00222933.2020.1867772, http://zenodo.org/record/540517
Mapping of literature on Bose – Einstein condensation
No full textThis paper attempts to highlight quantitatively the growth and development of research work in this field on Bose-Einstein Condensation (BEC) in terms of publication output as per Science Citation Index (1982-2005). During 1982–2005 a total of 5258 papers were published by the scientists in this field. The average number of publications published per year were 219. The highest number of papers 814 were published in 2004. There were 77 countries involved in the research in this field. USA is the top producing country with 1632 publications (31%) followed by Germany with 620 publications (11.79%). Authorship and collaboration trend was towards multiauthored papers. Intensive collaboration was found during 1996-2005. One paper “Astrophysical Journal 543 (1), (2000), L39-L42” had 56 collaborators. There were 1635 international collaborative papers. Bilateral collaboration accounted for 24 percent of total collaborative papers. National Institute of Standards & Technology (USA) topped the list with 179 publications followed by University of Colorado (USA) with 160 publications. The most prolific authors were: W. Ketterle (USA) with 93 publications, K. Burnett (England) and M. Lewenstein (England) with 68 publications each and S. Stringari with 57 publications. The most preferred journals by the scientists were : Physical Review- A with 1504 papers, Physical Review Letters with 824 papers, Journal of Physics-B with 205 papers, Physical Review- B with 178 papers, Physics Letters-A with157 papers, Physical Review –E with 122 papers and Journal of Low Temperature Physics with 102 papers. The high frequency keywords were : Bose-Einstein Condensation (2012), Gases (1928), Atoms (860), and Dynamics (493)
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