990 research outputs found
C.difficile infection rate in patients with IBD is falling in line with that of the general population
No full textPoster presentatio
Tuberculosis chemotherapy in the 21 st century: Back to the basics
No full textThe key to successful elimination of tuberculosis (TB) is treatment of cases with optimum chemotherapy. Poor chemotherapy over time has led to drug-resistant disease. Drug resistance of Mycobacterium tuberculosis develops by the selective growth of resistant mutants. The incidence of drug-resistant cases depends on the number of bacilli and the drug-resistant mutants in the lesion. The latter is low for individual drugs and even lower for two and three drugs. Therefore, use of combination chemotherapy with three or more drugs results in cure. However, irregular treatment, inadequate drugs, inadequate drug doses or addition of a single drug to a failing regimen allows selective growth of resistant mutants and acquired drug-resistant TB. Contacts of these resistant cases develop primary drug resistant TB. Thus, drug resistance in tuberculosis is a "man-made problem". Anti-TB chemotherapy must be given optimally by (i) ensuring adequate absorption of drugs, (ii) timely diagnosis and management of drug toxicities and (iii) treatment adherence. New classes of anti-TB drugs are needed; but are unlikely to become available soon. It is vital that the 21 st century physicians understand the basic principles of TB chemotherapy to ensure efficient use of available drugs to postpone or even reverse epidemics drug-resistant TB
India’s Long Road: The Search for Prosperity by Vijay Joshi
No full textVijay Joshi‟s India’s Long Road: The Search for Prosperity is an important addition to the list of books on the Indian economy–Jean Dréze and Amartya Sen‟s An Uncertain Glory: India and its Contradictions and Jagdish Bhagwati and Arvind Panagariya‟s Why Growth Matters: How Economic Growth in India Reduced Poverty and the Lessons for Other Developing Countries–written for the interested general reader as well as the specialist. In addition, those readers familiar with the literature assessing and evaluating India‟s economic reforms will remember Joshi as the co-author of India: Macroeconomics and Political Economy, 1964-1991(1994) and India's Economic Reforms, 1991-2001(1996) along with the late I. M. D. Little
Tuning Transitions in Rotating Rayleigh-Bénard Turbulence
No full textRayleigh-Bénard convection is a canonical system for the investigation of buoyancy-driven natural convection phenomena which abound in nature and technology. Under the influence of rotation and depending on the system parameters, the flow exhibits different regimes with disparate heat transfer characteristics even in the turbulent state. The present study attempts to tune the transitions between these regimes and thus control the heat transfer in practical applications. In particular, we explore the effect of addition of neutrally-buoyant thermally-conducting particles to the fluid. Following an experimental approach, we study the flow structure and heat transfer as functions of particle concentration and system parameters
Herbal drugs and fingerprints : evidence based herbal drugs / Devi Datt Joshi.
No full textIncludes bibliographical references and index.xvi, 252 pages :Evidence based herbal drugs are on hi-acceptance day by day due to health friendly nature compared to synthetic drugs. The active ingredients in herbal drugs are different chemical classes, e.g. alkaloids, coumarins, flavonoids, glycosides, phenols, steroids, terpenes etc., are identified at molecular level using current analytical practices, which are unique characteristic, as finger, so known as fingerprints. The fingerprints are used for assessment of quality consistency and stability by visible observation and comparison of the standardized fingerprint pattern, have scientific potential to decipher the claims made on these drugs for authenticity and reliability of chemical constituents, with total traceability, which starts from the proper identification, season and area of collection, storage, their processing, stability during processing, and rationalizing the combinational in case of polyherbal drugs. These quality oriented documents have ample scientific logics so well accepted globally by regulatory authorities and industries, to determine intentional/ unintentional contamination, adulteration, pollutants, stability, quality, etc. parameters. Based on geo-climatic factors, a same plant species has different pharmacological properties due to different ingredients; such regional and morphological variations are identified by fingerprints, at the time of collection of the medicinal herb. The chromatographic (TLC, HPTLC, HPLC, GC,) and spectral (UV-Vis., FTIR, MNR, MS, LC-MS, GC-MS etc.) techniques have world-wide strong scientific approval as validated methods to generate the fingerprints of different chemical classes of active ingredients of herbal drugs. Presently there is a need for a book having all the fingerprinting techniques for herbal drugs at a place with theory, case studies and art to discover patentable forms. The present book is a mile stone in the subject, to be utilized by Scientists, Medical Doctors, Technicians, Industrialists, Researchers, and Students both in PG and UG level
Random walk over a hypersphere
No full textIn a recent paper the author had shown that a special case of S. M. Joshi
transform (so named after the author's reverent father) of distributions
(Sba f)(x)=〈f(y), lFl(a0;b0;ixy) lFl(a;b;−2ixy)〉
is a characteristic function of a spherical distribution. Using the methods developed in that paper; the problem of distribution of the distance CD, where C and D are points niformly distributed in a hypersphere, has been discussed in the present paper. The form of characteristic function has also been obtained by the method of projected distribution.
A generalization of Hammersley's result has also been developed. The main purpose of the paper is to show that although the use of characteristic functions, using the method of Bochner, is available in problems of random walk yet distributional S. M. Joshi transform can be used as a natural tool has been proved for the first time in the paper
Oregon Health Authority - Highway 36 public health assessment
No full textprepared by the Environmental Health Assessment Program, Oregon Health Authority, Public Health Division ; authors: Sujata Joshi, MSPH, Epidemiologist, David Farrer, Ph.D., Toxicologist, Jae P. Douglas, MSW, Ph.D., Principal Investigator, Administrator, Center for Prevention and Health Promotion, Karen Bishop, MPH, Public Health Educator, Matthew Dubrow, D.O, Preventive Medicine Resident.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (pages 59-62).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Strained SOI FINFET SRAM design
No full textImpact of strained silicon effects in double-gated FinFET structures on static random access memory (SRAM) cell functionality is presented. Three FinFET silicon-on-insulator (SOI) SRAM cell embodiments representing unstrained, strained, and NFET-only-strained devices are compared against a planar PDSOI SRAM cell design. The metrics encompass both static and dynamic behavior of the cell and are analyzed through 2-D process hardware-calibrated device models (Lg = 25 nm). The key findings of this letter are: 1) PFET devices with tensile strain are found to degrade the FinFET cell Read Noise Margin and cell ability to write a strong 1; 2) by restricting the tensile strain to the NFET devices FinFET SRAM cell Read stability and access times improve by 10percent-20percent relative to their unstrained FinFET and NFET-only strained PDSOI counterparts. © 1980-2012 IEEE.[Anonymous], 2006, TAUR TSUPREM 4 VERS; BASKER VS, 2010, P S VLSI TECHN, P19; Buturla E., 1989, P NASECODE 6, P291; Joshi R, 2006, PROC EUR S-STATE DEV, P315; Joshi R., 2005, U. S. Patent, Patent No. [6 921 982, 6921982]; Maitra K, 2011, IEEE ELECTR DEVICE L, V32, P713, DOI 10.1109-LED.2011.2126556; Matsukawa T, 2009, 2009 SYMPOSIUM ON VLSI TECHNOLOGY, DIGEST OF TECHNICAL PAPERS, P118, DOI 10.1109-IWSDA.2009.5346407; SEEVINCK E, 1987, IEEE J SOLID-ST CIRC, V22, P748, DOI 10.1109-JSSC.1987.1052809; Shin K.-S., 2006, THESIS U CALIFORNIA; Thean A.V.-Y., 2005, IEDM, P509, DOI 10.1109-IEDM.2005.160939312
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