1,720,955 research outputs found
Efecto de la trombocitopenia en la morbimortalidad de los pacientes con infección por COVID 19: estudio de cohortes retrospectivo en un hospital público
Los pacientes afectados por el SARS CoV-2 suman más de 615 millones en el mundo (1), por ello es necesario contar con marcadores que identifiquen a los pacientes con mayor riesgo de complicaciones. Este estudio evalúa el efecto de la trombocitopenia en la morbimortalidad de los pacientes con SARS CoV-2. Se realizó un estudio de cohortes retrospectivo de los adultos hospitalizados con infección por SARS CoV-2 con trombocitopenia y con plaquetas normales. Se utilizó el test de Chi cuadrado o el Test de Fisher y el Test de Student para las variables cualitativas y cuantitativas, respectivamente. La edad y la diabetes mellitus se asociaron a mayor mortalidad en el análisis bivariado (p<0.05). El análisis multivariado concluyó que los Odds Ratio (OR) de los eventos muerte y requerimiento de ventilador mecánico se incrementan en los pacientes con trombocitopenia con un OR=3 y OR=2, respectivamente. Los pacientes con recuentos plaquetarios superiores a 300,000/mm3 tuvieron menor mortalidad con respecto a aquellos con recuentos normales pero inferiores a 300,000/mm3, OR 0.55 p<0.05. En conclusión, existe mayor requerimiento de ventilador mecánico y mortalidad en los pacientes con SARS CoV-2 y trombocitopenia. Un recuento plaquetario superior a 300,000/mm3 muestra un efecto protector para el evento mortalidad.More than 615 million people around the world have been infected with SARS CoV-2 (1), hence it is paramount to have biomarkers that identify patients with a greater chance of developing complications. Therefore, this study evaluates the effect of thrombocytopenia on the morbidity and mortality of patients with SARS CoV-2. It was conducted a retrospective cohort study of hospitalized adults with SARS CoV-2 infection with thrombocytopenia and normal platelets. The Chi-square test or the Fisher's test were used for the qualitive variables, whereas the Student's test was used for the quantitative ones. Age and diabetes mellitus were associated with higher mortality in the bivariate analysis (p<0.05). The multivariate analysis concluded that the Odds Ratio (OR) of the events of death and mechanical ventilator requirement increased in patients with thrombocytopenia with OR=3 and OR=2, respectively. Patients with a platelet count higher than 300,000/mm3 had lower mortality in comparison with those with regular counts but less than 300,000/mm3, OR 0.55 p<0.05. In light of the above, there is a higher requirement for a mechanical ventilator and mortality in patients with SARS CoV-2 and thrombocytopenia. Furthermore, a platelet count higher than 300,000/mm3 shows a protective effect on the mortality event
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Eficacia y seguridad de la esplenectomía en pacientes con púrpura trombocitopénica inmunológica crónica
Objetivo. Evaluar la eficacia y la seguridad de la esplenectomía en el corto y largo plazos en pacientes con púrpura trombocitopénica inmunológica crónica (PTIC) y determinar los predictores de respuesta a esta intervención. Material y métodos. Se realizó un estudio descriptivo y retrospectivo de 89 pacientes con PTIC (49 esplenectomizados y 40 no esplenectomizados) en el Hospital Nacional Arzobispo Loayza de Lima. Resultados. La respuesta inicial al tratamiento con corticoides fue completa en el 35% de los pacientes no esplenectomizados y en ninguno de los esplenectomizados, y hubo respuesta parcial en el 60,0% y 71,55%, respectivamente. El tiempo promedio entre el diagnóstico y la esplenectomía fue 24,01 ± 31,52 meses. Las complicaciones presentadas durante la cirugía (12%) y el postoperatorio (23%) se resolvieron totalmente en todos los casos. Ningún paciente falleció como consecuencia de la esplenectomía. La respuesta inicial a la esplenectomía fue completa en el 73,47% y parcial en el 18,37%. Al primer, segundo y tercer años de seguimiento, lasrespuestas completas y parciales fueron 72,91% y 18,75%, 69,44% y 19,44% y 67,74% y 16,13%, respectivamente. El promedio de plaquetas antes y después de la esplenectomía (p < 0,0000) y la cuenta de plaquetas al final del seguimiento en los esplenectomizados y los no esplenectomizados (p = 0,013) tuvieron diferencia significativa. Solo el promedio deplaquetas preoperatorio fue predictor de buena respuesta a la esplenectomía (p < 0,014). Conclusiones. La esplenectomía es un tratamiento eficaz y seguro para los pacientes adultos con PTIC
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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