7,173 research outputs found
lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulva development
No full textLate events in the cell-cell signalling pathway that controls the specification of vulva cell fates in C. elegans are characterized. The lin-31 gene acts downstream of the ras homolog let-60 and encodes a member of the HNF-3/fork head family of DNA-binding transcription factors. lin-31 regulates how vulval precursor cells choose their fate and in lin-31 mutants, these cells do not properly choose which fate to express and therefore adopt any of the 3 possible vulval cell fates in a deregulated manner..RE: 68 ref.; SC: CA; PE; 0TSource type: Electronic(1) http://upei-resolver.asin-risa.ca?sid=SP:CABI&id=pmid:&id=&issn=0890-9369&isbn=&volume=7&issue=6&spage=933&pages=933-947&date=1993&title=Genes%20and%20Development&atitle=lin-31%2c%20a%20Caenorhabditis%20elegans%20HNF-3%2ffork%20head%20transcription%20factor%20homolog%2c%20specifies%20three%20alternative%20cell%20fates%20in%20vulva%20development.&aulast=Miller&pid=%3Cauthor%3EMiller%2c%20L%20M%3bGallegos%2c%20M%20E%3bMorisseau%2c%20B%20A%3bKim%2c%20S%20K%3C%2Fauthor%3E%3CAN%3E19932337278%3C%2FAN%3E%3CDT%3EJournal%20article%3C%2FDT%3
Supplemental Material—Identifying research priorities with children, youth, and families: A scoping review
No full textSupplemental Material for Identifying research priorities with children, youth, and families: A scoping review by Shokoufeh Modanloo, Quinn Correll, Rhonda Correll, Nathalie Major, Michelle Quinlan, Jessica Reszel, Jodi Wilding, Zhi Lin Zhou, Linda S Franck, and Denise Harrison in Journal of Child Health Care</p
Vascular endothelial growth factor restores delayed tumor progression in tumors depleted of macrophages
No full textGenetic depletion of macrophages in Polyoma Middle T oncoprotein (PyMT)-induced mammary tumors in mice delayed the angiogenic switch and the progression to malignancy. To determine whether vascular endothelial growth factor A (VEGF-A) produced by tumor-associated macrophages regulated the onset of the angiogenic switch, a genetic approach was used to restore expression of VEGF-A into tumors at the benign stages. This stimulated formation of a high-density vessel network and in macrophage-depleted mice, was followed by accelerated tumor progression. The expression of VEGF-A led to a massive infiltration into the tumor of leukocytes that were mostly macrophages. This study suggests that macrophage-produced VEGF regulates malignant progression through stimulating tumor angiogenesis, leukocytic infiltration and tumor cell invasion
[[alternative]]Application of critical concepts, anaerobic power and energy expenditure in predicting rowing performance
No full text[[abstract]]Application of critical concepts, anaerobic power and energy expenditure in predicting rowing performance
June,2005 Hsin-Fu Lin
Advisor: Jung-Charng Lin,
Abstract
Critical velocity (CV) and critical power (CP) have been proposed to be effective indirect anaerobic threshold methods in monitoring training and predicting performance of rowing respectively. The purpose of this study was to compare these two indexes in predicting indoor rowing performance by combining different physiological variables, including maximal oxygen uptake ( VO2max ), anaerobic threshold (AT4) and modified Wingate test, which are important physiological variables in endurance performance. In addition, whether or not the physiological variables (VO2, VCO2, VE, HR, [La-]) under these two critical intensities were stable was also examined. Fifteen elite female rowers (age 20.73± 1.44 years, height 1.64 ±0.35m, weight 56.64±4.38kg) were recruited in this study. VO2max (2.47 ±0.47L) and AT4(157.81 ±22.08W) were measured during a discontinuous graded exercise test, starting at 100W, on a Concept II ergometer increased by 25 W for each 3-min stage. Four test times of duration 90s, 240s, 600s, and 1200s were used to determine CP (139.49 ±20.37W), whereas CV( 4.00 ±0.14m/s) was estimated by 400m, 600m, 800m, 1000m maximal exertion trials in different days as well by using Linear distance-time model. Peak power (353.48 ±27.71W), maximum power (350.12 ±26.72W), minimum power (336.85 ±21.58W), mean power (314.44 ±27.87W), fatigue index (max power - min power/ mean power) were obtained using a modified Wingate test protocol (30s sprint) on the ergometer. Physiological variation of intensity at CV and CP, including VO2, VCO2, VE, HR, [La-], were measured every 5 minutes in 20-min constant rowing tests. The results of study showed that VO2max, AT4, CP, CV, peak power, mean power were significantly correlated with 2000 indoor rowing performance (r=?0.84, ?0.85, ?0.81, ?0.97, ?0.66, ?0.67, P<0.01). By submitting mean power, fatigue index, VO2max, AT4 with each index to a stepwise regression analysis, it produced two individual critical concept models as following to predict 2000 indoor rowing performance: CV model: T2000= ?131.83 CV(m/s)?1.00 fatugue index(%) +1023.91 (R2=0.96, SEE=4.10, p<.05); CP model: T2000=?22.59 VO2max(L/min)?.38AT4(W)+608.58 (R2 =0.82, SEE=8.05, p<.05). When rowing at CV on indoor ergometer (14±4 min), VO2, VE, HR, [La-] didn’t reach steady state and VCO2 was not different at different time points. Under CP, VO2, VCO2 didn’t change with time, however, there were significant difference of VE, HR, [La-] at different time points. Our findings in this study indicated that CV has more predictive power, representing as anaerobic threshold, than AT4 to predict rowing performance. Besides CV, fatigue index from modified Wingate test is also an important determinant for 2000-m performance of female rowers. Therefore, comparing with CP, CV could be used when applying critical concept in training and evaluate indoor performance in rowing. In addition, both two-parameter-derived CV and CP in rowing do not represent sustainable steady state intensities.
Key words: critical velocity, critical power, anaerobic power, energy expenditure, rowing, performance.
Data analyses of honokiol-induced autophagy of human glioma cells in vitro and in vivo
No full textAbstractThis article contains raw and processed data related to a research, “Honokiol induces autophagic cell death in malignant glioma through reactive oxygen species-mediated regulation of the p53/PI3K/Akt/mTOR signaling pathway” (C.J. Lin, T.L. Chen, Y.Y. Tseng, G.J. Wu, M.H. Hsieh, Y.W. Lin, R.M. Chen, 2016) [1]. Data were obtained by immunoblotting analyses of light chain 3 (LC3)-II, beclin-1, Akt, and mTOR in human glioma U87 MG cells and mouse glioma tissues treated with honokiol, an active constituent extracted from the bark of Magnolia officinalis, “Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration” (P.S. Yeh, W. Wang, Y.A. Chang, C.J. Lin, J.J. Wang, R.M. Chen, 2016) [2]. The processed data show the effects of honokiol on induction of autophagy in human glioma U87 MG cells by analyzing levels of LC3-II, p62, and bectin-1, “Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells” (K.H. Chang, M.D Yan, C.J. Yao, P.C. Lin, G.M. Lai, 2013) [3]. In addition, chloroquine, a lysosomal inhibitor, was administered to the cells to further confirm honokiol-induced cell autophagy. Sequentially, mice with gliomas were created and treated with honokiol. Amounts of phosphorylated and non-phosphorylated Akt and mTOR in glioma tissues were analyzed to determine the possible mechanisms of honokiol-induced autophagy
Phoebus 9: Myriad Points of View
No full texttableOfContents: Preface p.9
Collecting Chinese Art p.13
Catalog p.15
The Daoist Symbolism of Immortality in Shen Zhou's Watching the Mid-Autumn Moon at Bamboo Villa by Chun-yi Lee p. 49
Wu Shi'en's Liang Hong and Meng Guang: A Misreading by XiaopIng Lin p.79
From the Profound to the Mundane: Depictions of Lohans in Late Ming China by Janet Baker p. 101
Glimpses of the Duanwu Festival by Fang Xun (1736-1799): Commemorative Painting or Private Souvenir? by Anne Kerlan-Stephens p. 117
Pleasure and Pain by Marion S. Lee p. 143
From Narrative to Transformed Narrative: Visualizations of the Heavenly Maiden and the Maiden Magu by Chen Liu p. 167
Glossary of Chinese Names and Terms p. 18
Neotypification and taxonomic status of Opephyllum martensii Schmitz in Schmitz et Hauptfleisch (Delesseriaceae, Rhodophyta) from Zamboanga, Southern Philippines
No full textThe monotypic delesseriaceous genus Opephyllum was created by Schmitz in Schmitz and Hauptfleisch for O. martensii, represented by a single collection from Zamboanga on the southwestern tip of Mindanao in the southern Philippines. As the type specimen or collection is no longer in existence, we are neotypifying the taxon based on recent topotype collections made in the spring of 1998. After comparison of this material with species of Martensia from the Indo-Pacific region and Caribbean Sea based on morphological evidence and sequence analysis of chloroplast-encoded rbcL and the nuclear-encoded large subunit ribosomal DNA gene (LSU rDNA), we conclude that Opephyllum is not generically distinct from Martensia despite its lack of the reticulate fenestrations that characterize fronds of every other species of the latter. We therefore propose the new combination Martensia martensii (Schmitz in Schmitz et Hauptfleisch) Lin, Fredericq et Liao for this rare member of the tribe Martensieae, subfamily Nitophylloideae.TR: CS0213352Source type: Electronic(1
Collision of Confucianism, Taoism and Christian Ideas： a Comparative Study of Culture Communication Sense of Pearl S. Buck and Lin Yutang
No full textPearl S. Buck and Lin Yutang differ in their culture communication sense. Through the comparative study of their subject choice and creation of hero or heroine’s fate, the author points out that Lin Yutang emphasizes on the spread of Chinese culture to westerners, while Pearl S. Buck expresses more western thoughts and Christian ideas. Key words: Pearl S. Buck, Lin Yutang,culture communication sense,Confucianism,Taoism,Christian ideas Résumé Pearl Buck et Lin Yutang diffèrent dans la conscience de la diffusion culturelle exprimé dans leurs oeuvres. Cet article signale , par la comparaison des sujets et de la destinée des personnages dans les oeuvres de ces deux écrivains, que Lin Yutang met l’accent sur la diffusion du confucianisme et du taoïme vers les Occidentaux tandis que Pearl Buck propage davantage les notions occidentals et les idées chrétiennes. Mots clés: Pearl Buck, Lin Yutang, la conscience de la diffusion culturelle, le confucianisme et le taoïsme, les idées chrétiennes 摘 要 賽珍珠和林語堂在作品中表現的文化傳播意識不盡相同，本文通過兩位作家在選題與人物命運安排上的差異，指出林語堂重在向西方人傳播中國的儒道思想，而賽珍珠則更多地宣揚了西方觀念和基督教思想。關鍵詞：賽珍珠；林語堂；文化傳播意識；儒道思想；基督教思
2017-3-1 Table S1.pdf
No full textAuthor(s): Fei Lin Article Title: A formulation of neem cake seeded with Bacillus sp. provides control over tomato
Fusarium crown and root rotArticle doi: http://dx.doi.org/10.1080/09583157.2017.1296106Supplemental Table S1</div
The design of a radio altimeter using frequency modulation method
No full textThesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering, 1937 [second author], and Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Aeronautical Engineering, 1937 [first author].MICROFICHE COPY AVAILABLE IN ENGINEERING.Includes bibliographical references (leaves 108-110).by Shih-Nge Lin, Ieu-Liang Wu.M.S
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