13 research outputs found

    Significant increase in cyanide degradation by Bacillus sp. M01 PTCC 1908 with response surface methodology optimization

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    Abstract Cyanide is used in many industries despite its toxicity. Cyanide biodegradation is affordable and eco-friendly. Sampling from cyanide-contaminated areas from the Muteh gold mine and isolation of 24 bacteria were performed successfully. The selected bacteria—‘Bacillus sp. M01’—showed maximum tolerance (15 mM) to cyanide and deposited in Persian Type Culture Collection by PTCC No.: 1908. In the primary experiments, effective factors were identified through the Plackett–Burman design. In order to attain the maximum degradation by Bacillus sp. M01 PTCC 1908, culture conditions were optimized by using response surface methodology. By optimizing the effective factor values and considering the interaction between them, the culture conditions were optimized. The degradation percentage was calculated using one-way ANOVA vs t test, and was found to have increased 2.35 times compared to pre-optimization. In all of the experiments, R2 was as high as 91%. The results of this study are strongly significant for cyanide biodegradation. This method enables the bacteria to degrade 86% of 10 mM cyanide in 48 h. This process has been patented in Iranian Intellectual Property Centre under Licence No: 90533

    A Critique on the Book Philosophical Writing: An Introduction

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    This article reviews the book Philosophical Writing: An Introduction by A. P. Martinich, translated by Fatemeh Minaei and Layla Minaei. The purpose of this book is to teach the writing of a philosophical article and not to mention other types of philosophical writing. The book methodically looks at all the necessary details of the philosophical article and gives the reader how to write a precise, understandable and authoritative article. Martinich in this book helps the reader not merely be the reporter of other people's opinions, but first of all, he learns the students how to express his/her thoughts and opinions, to write it, to compare other opinions in relation to it and how to defend his/her opinion. In this paper, after the introduction, a brief overview of the author and translator is presented, and as this book is valuable, so it isintroduced in detail. Then, it's privileges and defects and outcome

    18F-FDG PET/MRI and 18F-FDG PET/CT for the Management of Gynecological Malignancies: A Comprehensive Review of the Literature

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    Objective: Positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro- D-glucose integrated with computed tomography (18F-FDG PET/CT) or magnetic resonance imaging (18F-FDG PET/MRI) has emerged as a promising tool for managing various types of cancer. This review study was conducted to investigate the role of 18F- FDG PET/CT and FDG PET/MRI in the management of gynecological malignancies. Search strategy: We searched for relevant articles in the three databases PubMed/MEDLINE, Scopus, and Web of Science. Selection criteria: All studies reporting data on the FDG PET/CT and FDG PET MRI in the management of gynecological cancer, performed anywhere in the world and published exclusively in the English language, were included in the present study. Data collection and analysis: We used the EndNote software (EndNote X8.1, Thomson Reuters) to list the studies and screen them on the basis of the inclusion criteria. Data, including first author, publication year, sample size, clinical application, imaging type, and main result, were extracted and tabulated in Excel. The sensitivity, specificity, and diagnostic accuracy of the modalities were extracted and summarized. Main results: After screening 988 records, 166 studies published between 2004 and 2022 were included, covering various methodologies. Studies were divided into the following five categories: the role of FDG PET/CT and FDG-PET/MRI in the management of: (a) endometrial cancer (n = 30); (b) ovarian cancer (n = 60); (c) cervical cancer (n = 50); (d) vulvar and vagina cancers (n = 12); and (e) gynecological cancers (n = 14). Conclusions: FDG PET/CT and FDG PET/MRI have demonstrated potential as non-invasive imaging tools for enhancing the management of gynecological malignancies. Nevertheless, certain associated challenges warrant attention

    Cataloging Archival Records of the National Library and Archives of Iran Based on the International Standard Archival Description (ISAD). 3. 2012; 21 (4) :114-134

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    Purpose: Records catalogues at the National Archives of Iran and the level of their conformity with the International Standard Archival Description (ISAD). The present research is aimed at identifying descriptive elements of the archival. Methodology: Standards, and interviews are employed for gathering research data. e results are presented in tables and -gures through descriptive statistical methods (frequency and percentage). The research community included researchers and experts in arrangement and description of records, manuals, and cataloging worksheets of the archival records existing in National Library and Archives of Iran. This research was based on analytical survey. A checklist, the rules of archival Findings: The research findings also show that information elements including “Author Name” (16.62%) and “Descriptors” (91.26%) are consistent with documentation tools. 8.8% of these information elements are not documented at all. In the eyes of the experts of arrangement and description of documents, cataloging of archival documents based on ISAD has improved the methods of organizing documents. Conclusion: Applying this standardized method of archival description has led to better retrieval of the related documents. This research displays the conformity of descriptive elements in the studied worksheets

    The impact of low and no-caloric sweeteners on glucose absorption, incretin secretion and glucose tolerance

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    The consumption of non-nutritive, low or no-calorie sweeteners (LCS) is increasing globally. Previously thought to be physiologically inert, there is a growing body of evidence that LCS not only provide a sweet taste but may also elicit metabolic effects in the gastrointestinal tract. This review provides a brief overview of the chemical and receptor-binding properties and effects on chemosensation of different LCS but focuses on the extent to which LCS stimulates glucose transport, incretin and insulin secretion, and effects on glucose tolerance. Aspartame and sucralose both bind to a similar region of the sweet receptor. For sucralose, the data are contradictory regarding effects on glucose tolerance in humans and may depend on the food or beverage matrix and the duration of administration, as suggested by longer-term rodent studies. For aspartame, there are fewer data. On the other hand, acesulfame-potassium (Ace-K) and saccharin have similar binding characteristics to each other but, while Ace-K may increase incretin secretion and glucose responses in humans, there are no data on saccharin except in rats, which show impaired glucose tolerance after chronic administration. Additional research, particularly of the effects of chronic consumption, is needed to provide concrete evidence for beneficial or detrimental effects of LCS on blood glucose regulation in humans.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author

    مروری بر زندگی و آثار مشاهیر طب سنتی ایران و اسلام در منطقه خراسان

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    The history of every nation is part of the nation's identity as a precious heritage that must be protected. Iran has also given several thousand years of civilization heritage of science and scientists in different sciences is a huge treasure. In particular in the history of Iranian scientists in the field of medicine and pharmacy were known. In the past, Khorasan was an important area of Iran. And many physicians have left in this area. It can be said from the land of Khorasan, ITM has grown and spread to surrounding lands. In this review study, by examining the medical history books and literature to introduce the life and works of famous sages of traditional medicine that have emerged from Khorasan region will be discussed. The fourth and fifth centuries AH, centuries of Islam and Iranian culture and civilization are proud. In the 4th AH century, Bukhari al-Akhaweyni, wrote the first comprehensive book called Hydayat al-motealemyn in ITM and Abu Mansour Heravi, wrote the first book of Pharmacy named al-Abniyeh An-Haghyegh al-Advie. The most ancient poetic work in ITM that called Daneshname was written by Hakim Meysari. In the 5th AH century Avicenna, the greatest scholar in ITM and author of the Canon of Medicine and Neyshabouri, known as the second Hippocrates, lived in Khorasan respectively. In later centuries, following the Mongol attack of Iran, were seen a period of decline. In the Safavieh period (10th AHcentury), Hakim Yousefi Heravi wrote several medical books of poetry and Aghili Khorasani renowned physician of the 12th AHcentury, is the author of the Makhzan al-Adviye and Kholasat al-Hikmat.     Please cite this article as: Khorram Pakhouh H, Feyzabadi Z, Khodabakhsh M, Saket KH. An Overview of the Life and Works of Famous Iranian Traditional Medicine and Islam in Khorasan. Med Hist J 2016; 8(28): 37-46. Iranian Traditional Medicine (ITM); History of Medicine; Khorasan; Avicennaپیشینه تاریخی هر ملتی جزئی از هویت آن ملت می‌باشد که باید از آن به عنوان میراث گران‌بهایی محافظت نمود. ملت ایران نیز با توجه به تمدن چندهزار ساله خود میراث‌دار گنج عظیمی از دانش و دانشمندان در علوم مختلف می‌باشند. به ویژه در طول تاریخ نام دانشمندان ایرانی در حوزه طب و داروسازی خوش درخشیده است. خراسان در گذشته، منطقه وسیع و پراهمیت از ایران بوده است و حکیمان و اطبای زیادی از این منطقه پا به عرصه علم طب گذاشته‌اند. می‌توان گفت طب سنتی ایران از سرزمین خراسان بزرگ شده، رشد کرده و به سرزمین‌های اطراف گسترش یافته است. در این مطالعه، با بررسی کتب تاریخ پزشکی ایران و متون طب سنتی ایران و بررسی مقالات تاریخ پزشکی چاپ‌شده، به معرفی زندگی و آثار پزشکان مشهوری که از منطقه خراسان برخاسته‌اند می‌پردازیم. قرن‌های چهارم و پنجم قمری، سده‌های پرافتخار در فرهنگ و تمدن اسلام و ایران می‌باشند، در قرن چهارم قمری اخوینی بخارایی، اولین کتاب جامع طب سنتی ایران به زبان فارسی ـ هدایه المتعلمین ـ و ابومنصور هروی، اولین کتاب داروسازی سنتی به زبان فارسی ـ الابنیه عن الحقایق الادویه ـ را نگاشتند. حکیم میسری کهن‌ترین اثر منظوم در طب به نام دانشنامه را به زبان فارسی نگاشته است. شیخ‌الرییس بوعلی سینا، بزرگ‌ترین دانشمند جهان اسلام و ایران ـ صاحب کتاب وزین قانون ـ و ابی صادق نیشابوری ملقب به بقراط ثانی، از پزشکان نامی خراسان می‌باشند. در قرون بعدی به دنبال حمله مغول به ایران دوره‌ای از افول در علم به وجود آمد و ردپایی از دانشمندان بزرگ و آثار آن‌ها در خراسان به چشم نمی‌خورد. در دوره صفویه (قرن 10 ق.)، حکیم یوسفی هروی چندین منظومه در پزشکی می‌نگارد. از دانشمندان قرن 12 از محمدحسین عقیلی خراسانی، پزشک نامدار و صاحب کتاب‌های خلاصه الحکمه و مخزن الادویه می‌توان نام برد

    Low-Fat Cheese Ameliorates Glucose Intolerance and Normalizes Insulin Secretion in a Rat Model of Type 2 Diabetes by Promoting β-cell Recovery

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    We aimed to determine if cheese could reduce glucose intolerance in aged rats with overt type 2 diabetes (T2D). Male Sprague-Dawley rats treated with high-fat diet and streptozotocin (STZ) exhibited hyperglycemia to elicit T2D. One week after STZ injection, low-fat (LOW) or regular-fat (REG) cheese was provided for 5 weeks and compared with T2D and low-fat diet reference (REF) groups. Food intake and weight gain were similar in all groups. Oral glucose tolerance tests revealed glucose intolerance in T2D rats that was partially ameliorated by LOW but not REG. Insulin secretion during the OGTT was impaired in T2D and REG at 10 min (pThe presentation of the authors' names and (or) special characters in the title of the pdf file of the accepted manuscript may differ slightly from what is displayed on the item page. The information in the pdf file of the accepted manuscript reflects the original submission by the author

    The effect of health belief-based education on physical activates of nulliparous women: A randomized control trial

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    Background: Regular physical activity during pregnancy is known to have positive effects on the health of the mother and fetus. However, reports indicate that more than half of pregnant women in Iran do not have adequate physical activity. This study was conducted in order to change the behavior of pregnant women in regard to physical activity and also to develop suitable educa-tional/interventional measures. Objectives: This study was conducted to investigate the effects of health belief-based education on the physical activity of nulli-parous women. Methods: This triple blinded randomized control trial was conducted among 64 nulliparous women attending the health centers of Ilam, Iran, in 2018. Participants were selected randomly by the cluster sampling method and were allocated to the two groups of control and intervention. Participants in the intervention groups received education and theoretical training based on the health belief model for at least 45 minutes, and then individual practical training was provided. Samples in the control group received routine pregnancy training. Data were collected in two pre-test and post-test stages by a valid questionnaire and were analyzed by SPSS, version 19, using statistical tests, including Chi-square, paired t-test, and independent t-test. Results: The results showed that the levels of perceived sensitivity (-4.750 ± 2.119), (t = 12.215, P ≤ 0.001), perceived severity of threat (-5.312 ± 1.874), (t =-16.036, P < 0.001), perceived benefits (-2.750 ± 1.502), (P < 0.001, t =-10.352), and self-efficacy (-3.656 ± 1.405), (P < 0.001, t =-14.708) in the intervention group significantly increased after the training compared to pre-training. Also, the level of perceived barriers (4.093 ± 1.444), (P < 0.001, t = 16.027) after the training was significantly less than pre-training level. In the intervention group, the total physical activity with the intensity of moderate/severe (2049/000 ± 963.342), (P < 0.001, t =-12.032) was significantly higher than pre-training. Conclusions: The results of this study indicated that training based on the health belief model can increase the physical activity of pregnant women with moderate/severe intensity and bring it to the optimal level of 150 minutes per week by increasing the health beliefs of pregnant women. Therefore, it is suggested that training based on this model should be appropriately incorporated into the routine education of pregnant women. © 2020, Author(s)

    Determining Health Literacy Level and Its Related Factors Among Pregnant Women Referred to Medical and Health Centers of Tehran in 2019: A Cross-sectional Study

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    Background: The ability to acquire, process, and understand health information to make informed decisions about health is de-fined as health literacy. A low level of health literacy disrupts women’s ability to understand and use health information in order to take appropriate and timely measures during pregnancy. Objectives: Due to the importance of health literacy during pregnancy and its direct impact on fetal health, this study was conducted to determine the level of health literacy and its related items among the pregnant women referred to medical and health centers in Tehran. Methods: This descriptive-analytical study was conducted on 270 pregnant women referred to the medical and health centers of Tehran in 2019. The participants in this study were selected by the mixed sampling method (cluster and random methods to select health centers and the convenience method to select participants). Data collection tools included a questionnaire for demographic and midwifery characteristics and a specialized questionnaire for maternal health literacy in pregnancy (MHELIP). Data analysis was performed by SPSS-19 software. Results: The mean age of the participants was 28.16 ± 5.70 years, and the mean gestational age was 24.50 ± 9.25 weeks. The mean score of health literacy among pregnant women was 63.14 ± 9.63, and 48.9 of them had limited (inadequate and insufficient) health literacy. The results showed positive correlations between the total score of health literacy and the demographic variables of age (P = 0.025), education (P = 0.003), and income (0.008), but no significant relationship was found between the mean total score of health literacy and employment status (P = 0.614) or parity (P = 0.614). Conclusions: It was found that limited health literacy had a high prevalence among pregnant women. Given the importance of pregnancy, it seems necessary for healthcare policymakers to design programs to promote women’s health literacy during preg-nancy. © 2021, Author(s)
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