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Transformations of respiratory epitelium in fibrous stage of acute respiratory distress-syndrome = Трансформация респираторного эпителия в фазу фиброза острого респираторного дистресс-синдрома
No full textNovikov Nikolay, Tumansky Valery, Fedotov Vasiliy. transformations of respiratory epitelium in fibrous stage of acute respiratory distress-syndrome = Трансформация респираторного эпителия в фазу фиброза острого респираторного дистресс-синдрома. Journal of Health Sciences. 2014;4(14):117-120. ISSN 1429-9623 / 2300-665X.
http://ojs.ukw.edu.pl/index.php/johs/article/view/2014%3B4%2814%29%3A117-120
http://journal.rsw.edu.pl/index.php/JHS/article/view/2014%3B4%2814%29%3A117-120
https://pbn.nauka.gov.pl/works/512256
DOI: 10.5281/zenodo.13322
http://dx.doi.org/10.5281/zenodo.13322
The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1107. (17.12.2013).
© The Author (s) 2014;
This article is published with open access at Licensee Open Journal Systems of Radom University in Radom, Poland
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This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
Conflict of interest: None declared. Received: 15.11.2014. Revised 05.12.2014. Accepted: 10.12.2014.
transformations of respirAtory epitelium in fibrous stage of acute respiraTory distress-syndrome
Трансформация респираторного эпителия в фазу фиброза острого респираторного дистресс-синдрома
Nikolay Yu Novikov
Crimean State Medical University, Simferopol, Russian Federation
Valery Alexeevich Tumansky
Zaporozhye State Medical University, Ukraine
Vasiliy Vladimirovich Fedotov
Crimean State Medical University, Simferopol, Russian Federation
Corr. Author
Новиков Николай Юльевич
докт. мед. наук, доцент ГУ «КГМУ имени С.И.Георгиевского», РФ, г. Симферополь
Е-mail: [email protected]
Трансформация респираторного эпителия в фазу фиброза острого респираторного дистресс-синдрома
АННОТАЦИЯ
Цель. Определение признаков эпителиально-мезенхимальной трансформации (ЭМТ) для установления ее роли в развитии фиброза легких у пациентов с острым респираторным дистресс-синдромом. Метод. Иммуногистохимическое окрашивание гистологических срезов. Результат. В большинстве альвеолоцитов обнаруживается экспрессия маркеров эпителиального иммунофенотипа. Признаки мезенхимальной дифференцировки определяются в единичных альвеолоцитах. Вывод. ЭМТ не играет существенной роли в формировании фиброза респираторного отдела при ОРДС.
Ключевые слова: респираторный эпителий; легкие; дистресс-синдром.
transformations of respirAtory epitelium in fibrous stage of acute respiraTory distress-syndrome
ABSTRACT
The epithelial-mesenchimal transition of respiratory epithelium in Acute Respiratory Distress Syndrome (ARDS) was goal of investigation. Postmortem immunohistochemical stain of respiratory part histological sections was methods. Result: epithelial immunofenotype of epithelial cells was determinate in more cases. Conclusion. The epitelial-mesenchimal transition does not play main role to lungs fibrosis in ARDS.
Keywords: respiratory epitelium; lungs; distress-syndrome.Novikov Nikolay, Tumansky Valery, Fedotov Vasiliy. Transformations of respiratory epitelium in fibrous stage of acute respiratory distress-syndrome = Трансформация респираторного эпителия в фазу фиброза острого респираторного дистресс-синдрома. Journal of Health Sciences. 2014;4(14):117-120. ISSN 1429-9623 / 2300-665X.
http://ojs.ukw.edu.pl/index.php/johs/article/view/2014%3B4%2814%29%3A117-120
http://journal.rsw.edu.pl/index.php/JHS/article/view/2014%3B4%2814%29%3A117-120
https://pbn.nauka.gov.pl/works/512256
DOI: 10.5281/zenodo.13322
http://dx.doi.org/10.5281/zenodo.1332
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Website: www.noveltyjournals.com
Published Date: 20-July-2023
DOI: https://doi.org/10.5281/zenodo.8167782
Paper Download Link (Source)
https://www.noveltyjournals.com/upload/paper/THE%20IMPACT%20OF%20SOCIOECONOMIC-20072023-3.pdfInternational Journal of Novel Research in Education and Learning, ISSN 2394-9686, Novelty Journals, Website: www.noveltyjournals.co
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