1,428 research outputs found
Spinocerebellar Ataxia Type 35 Caused by a New TGM6 Variant: Video Documentation of a German Family
No full textUvodnik [v angleščini]
Full text linkThe winter issue of Volume 11 presents a selection of seven different research articles on Japanese, Tetun Dili, Sylheti Bangla, Pahari, and Saraiki language. The rise of the Covid-19 pandemic, of which continuation unfortunately still allows many to collect data for research, has prompted us to publish several other interesting studies. This compilation brings to the readers the following topics.
This issue opens with Saki AMANO’s paper “Polysemy of ‘Common Language’ and the Modern Japanese Nation: The Universalization of a ‘Standard Language’ to correct ‘Dialects’?”. The author examines the term futsūgo (common language) over two periods and explains the shift from the populace’s everyday commonplace language to a unified national language.
In the next paper “From Native-speaker Likeness to Self-representation in Language: Views from the Acquisition of Japanese Transitive and Intransitive Verbs”, ITO Hideaki considers the degree to which a language user’s own will is recognized in language education. The author demonstrates that the usage-centric acquisition process can create opportunities for language users to make expressive choices focused on what they wish to say.
The third article is Nastja PAHOR’s paper “Corpus analysis of the collocations of the transitive verbs owaru and oeru”, in which the author approaches the transitivity of Japanese verbs from the corpus perspective. Semantical analysis of collocations in combination with the morphological analysis of co-occurring verbs reveals some interesting findings.
After the first three papers that focus on Japanese, the fourth one brings some new insights into Tetun Dili. Andrei A. AVRAM in his paper “Contact-induced variation in Tetun Dili phonology” analyzes Portuguese influence on Tetun Dili phonology, and demonstrates that the intricacies of inter-speaker variation cannot be merely reduced to variation between more Portuguese-like phonology and a more Tetun-Dili-like one.
Arpita GOSWAMI’s paper “Marked Geminates as Evidence of Sonorants in Sylheti Bangla: An Optimality Account” analyzes the universal concept that sonorants are marked geminates in the gemination process of Sylheti Bangla, and proposes a hierarchy of the constraints for analyzing the gemination processes in SHB. Besides, the author illustrates some additional constraints found to be necessary.
The following article “Stop Voicing and F0 Perturbation in Pahari” presents the findings of Nazia RASHID, Abdul Qadir KHAN, Ayesha SOHAIL, and Bilal Ahmed ABBASI. The authors investigate the perturbation effect of the voicing of initial stops on the fundamental frequency of the following vowels in Pahari.
Last but not least, “Word Stress system of the Saraiki language” is an article by Firdos ATTA, who presents an Optimality-Theoretic analysis of Saraiki word stress. The author concludes that Saraiki has a trochaic stress system and falls in the category of quantity-sensitive languages. This paper also indicates further research work on word stress at the sentence level.
Editors and Editorial board wish the regular and new readers of the ALA journal a pleasant read full of inspiration, and a rise of new research ideas inspired by these papers
Predgovor (v angleščini)
Full text linkIn these strange days of a limited physical and social contact due to the worldwide pandemic we are especially grateful for the existence of the parallel virtual world, which goes beyond human shortcomings. Our work continued without any obstructions and we are pleased to announce the summer ALA issue of the year 2020. In it we offer six research articles that extend over a broad linguistic area and include languages of the far East Asia, namely Mandarin Chinese, Japanese, Korean, and Vietnamese.
The issue opens with the WU Jiayi’s article “Contextual Conditions and Constraints in Chinese Dangling Topics: Syntax-Discourse Interface Analysis”, in which the author revisits dangling topics in Mandarin Chinese from the semantic and syntactic view, and evolves their findings to the hypothesis concerning language typology.
The second article on Chinese is Tina ČOK’s “Lexical Aspect Classification for Unrelated Languages: A Case Study on Slovenian and Chinese Lexical Aspect”, in which the author analyzes Chinese and Slovenian verb aspect to show that deeper cognitive differences effect our perception of reality, and upon her findings proposes an upgraded general classification of verb types.
The following article entitled “The New Chinese Corpus of Literary Texts Litchi” by Mateja PETROVČIČ, Radovan GARABÍK, and Ľuboš GAJDOŠ presents a newly launched corpus of Chinese literary texts Litchi, and exemplifies the variety of its benefits.
Furthermore, Petra JAKLIN “The Many Meanings of the Japanese Causative:Widening the Pragmatic Take on the -(sa)seru Causative Sentence” is an article in which the author revisits the range of possible interpretations and meanings carried by Japanese causative sentences, and supports her conclusions with comparisons to English and Croatian structures.
HWANG Yoong Hee’s article “Normative Forms and Synthetic Structure of Japanese in the Incubation Period of L2: Subject to Sentence-final Forms in Longitudinal Discourse Data of Korean Returnee Sisters’ Japanese” focuses on L2 Japanese sentence-final forms and their change mechanism in case of Korean returnees.
Last but not least, “Examining the Part-of-speech Features in Assessing the Readability of Vietnamese Texts” is an article by An-Vinh LUONG, Diep NGUYEN, and Dien DINH that discusses the present state of research on text readability in Vietnamese and proposes an improved model on estimating readability of texts and consequently their classification.
Editors and Editorial board wish the regular and new readers of the ALA journal a pleasant read full of inspiration.
EditorsIn these strange days of a limited physical and social contact due to the worldwide pandemic we are especially grateful for the existence of the parallel virtual world, which goes beyond human shortcomings. Our work continued without any obstructions and we are pleased to announce the summer ALA issue of the year 2020. In it we offer six research articles that extend over a broad linguistic area and include languages of the far East Asia, namely Mandarin Chinese, Japanese, Korean, and Vietnamese.
The issue opens with the WU Jiayi’s article “Contextual Conditions and Constraints in Chinese Dangling Topics: Syntax-Discourse Interface Analysis”, in which the author revisits dangling topics in Mandarin Chinese from the semantic and syntactic view, and evolves their findings to the hypothesis concerning language typology.
The second article on Chinese is Tina ČOK’s “Lexical Aspect Classification for Unrelated Languages: A Case Study on Slovenian and Chinese Lexical Aspect”, in which the author analyzes Chinese and Slovenian verb aspect to show that deeper cognitive differences effect our perception of reality, and upon her findings proposes an upgraded general classification of verb types.
The following article entitled “The New Chinese Corpus of Literary Texts Litchi” by Mateja PETROVČIČ, Radovan GARABÍK, and Ľuboš GAJDOŠ presents a newly launched corpus of Chinese literary texts Litchi, and exemplifies the variety of its benefits.
Furthermore, Petra JAKLIN “The Many Meanings of the Japanese Causative:Widening the Pragmatic Take on the -(sa)seru Causative Sentence” is an article in which the author revisits the range of possible interpretations and meanings carried by Japanese causative sentences, and supports her conclusions with comparisons to English and Croatian structures.
HWANG Yoong Hee’s article “Normative Forms and Synthetic Structure of Japanese in the Incubation Period of L2: Subject to Sentence-final Forms in Longitudinal Discourse Data of Korean Returnee Sisters’ Japanese” focuses on L2 Japanese sentence-final forms and their change mechanism in case of Korean returnees.
Last but not least, “Examining the Part-of-speech Features in Assessing the Readability of Vietnamese Texts” is an article by An-Vinh LUONG, Diep NGUYEN, and Dien DINH that discusses the present state of research on text readability in Vietnamese and proposes an improved model on estimating readability of texts and consequently their classification.
Editors and Editorial board wish the regular and new readers of the ALA journal a pleasant read full of inspiration.
Editor
The effect of inadvertent systemic hypothermia after mechanical thrombectomy in patients with large-vessel occlusion stroke
Full text linkBackground and aimsPostinterventional hypothermia is a frequent complication in patients with large-vessel occlusion strokes (LVOS) after mechanical thrombectomy (MT). This inadvertent hypothermia might potentially have neuroprotective but also adverse effects on patients’ outcomes. The aim of the study was to determine the rate of hypothermia in patients with LVOS receiving MT and its influence on functional outcome.MethodsWe performed a monocentric, retrospective study using a prospectively derived databank, including all LVOS patients receiving MT between 2015 and 2021. Predictive values of postinterventional body temperature and body temperature categories (hyperthermia (≥38°C), normothermia (35°C–37.9°C), and hypothermia (<35°C)) on functional outcome were analyzed using multivariable Bayesian logistic regression models. Favorable outcome was defined as modified Rankin Scale (mRS) ≤3.ResultsOf the 480 included LVOS patients with MT (46.0% men; mean ± SD age 73 ± 12.9 years), 5 (1.0%) were hyperthermic, 382 (79.6%) normothermic, and 93 (19.4%) hypothermic. Postinterventional hypothermia was significantly associated with unfavorable functional outcome (mRS > 3) after 90 days (OR 2.06, 95% CI 1.01–4.18, p = 0.045). For short-term functional outcome, patients with hypothermia had a higher discharge NIHSS (OR 1.38, 95% CI 1.06 to 1.79, p = 0.015) and a higher change of NIHSS from admission to discharge (OR 1.35, 95% CI 1.03 to 1.76, p = 0.029).ConclusionApproximately a fifth of LVOS patients in this cohort were hypothermic after MT. Hypothermia was an independent predictor of unfavorable functional outcomes. Our findings warrant a prospective trial investigating active warming during MT
Spezifischer Einfluss multipotenter Stromazellen auf die Zytostatikasensitivität kolorektaler Karzinomzellen
Full text linkMultipotente Stromazellen (MSC) nehmen am Aufbau des Tumorstromas teil und gelten als therapieresistent. In der vorliegenden Arbeit wurde in vitro gezeigt, dass MSC eine spezifische Zytostatikaresistenz von kolorektalen Karzinomzellen (CRC) gegenüber 5-Fluorouracil (5-FU) vermitteln, im Vergleich zu weiteren Stromazellen. Dies erfolgt teils über lösliche Faktoren der Stromazellen und Suppression des 5-FU-bedingten Zellzyklusarrests für die CRC-Zelllinie HCT8. MSC fördern darüber hinaus das Wachstum von CRC-Zellen im 2D-Modell und 3D-Sphäroidmodell und vermitteln morphologische Veränderungen von CRC-Zellen, welche bei der epithelial-mesenchymalen Transition vorkommen. Die Identifikation der beteiligten Mechanismen und die therapeutische Inhibition dieser birgt daher die Möglichkeit Tumorzellen gegenüber Therapeutika zu sensitivieren und somit den Erfolg von Tumortherapien zu steigern.Multipotent stromal cells (MSC) participate in forming the tumor stroma and are regarded as therapy-resistant. In this present work it has been shown in vitro, that MSC promote specific drug resistance of colorectal carcinoma (CRC) cells against 5-fluorouracil (5-FU),compared to other stromal cells. This is partially due to soluble factors of the stromal cells and suppression of the 5-FU-induced cell cycle arrest of the CRC cell line HCT8. Furthermore MSC support the growth of CRCcells in the 2D model and 3D spheroid model, and mediate morphological changes of CRC cells that occur in the epithelial-mesenchymal transition. The identification of the involved mechanisms and their therapeutic inhibition therefore bears the potential to sensitize tumor cells to therapeutics and thus to increase the success of tumor therapies.vorgelegt von Ala Jamou
Academic Library Streaming Video Revisited
No full textPresentation made at ALA Annual Conference, Sunday, June 26, 201
Predgovor
Full text linkAny scientific discipline undoubtedly encounters different challenges in their development over time. However, with the rise of modern technologies, such challenges expanded to new dimensions.
In linguistics, corpus studies have already proven their advantages, and many researchers and other users enjoy the richness of different corpora, spreading enthusiasm and courage to treat linguistics interdisciplinarily. At the same time, minority languages and poorly studied languages are also gaining researchers\u27 attention. Modern technologies further motivated different translation tools, which globalize the world with an enormous speed and seems to dicrease the relevance of language study and foreign language learning. However, the needs for interest in languages remain high. Though perhaps in a different form.
This issue comprises the above ideas in five articles.
Mayuri L. DILIP and Rayesh KUMAR coauthored the article “Clitic or Agreement Restriction in Santali: A Typological Analysis”, in which they investigated the syntactic configuration of pronominal number marking in Santali, the third most-spoken Austroasiatic language, from syntactic, morphological and prosodic perspective.
The following article “Contextual factors and language: an analysis of order placements” was written by Andrej BEKEŠ. It tackles Japanese in a specific social context, namely written ordering requirements on a crowdsourcing website, and reports negative correlation between the level of added value of such requirements and the quality of linguistic expression, comparing it to the Grice’s maxims of conversation.
ITO Hideaki\u27s article “Orthoepic Competence Descriptors in Japanese Language Education: CEFR Levels B1 to C2” overviews the Common European Framework of Reference for Languages (CEFR) and the JF Standard for Japanese-Language Education to discuss the benefits of their merging. In particular, the author re-examines CEFR descriptors for levels B1 to C2 in a non-alphabetically transcribed Japanese, which have not yet been attempted, and combine them with the results for levels A1 and A2 to present descriptors for levels A1 to C2 in overall.
KIM Yu Young in his article “Development and Operation Results of Japanese Accent Perception Test Based On e-learning System” introduced the [AJ-phonetic Test] system, an online tool for practicing perception of Japanese word accent, presented its benefits through a longitudinal study on Korean learners of Japanese.
Finally, Miha PAVLOVIČ wrote an article entitled “Grammar Errors by Slovenian Learners of Japanese: Corpus Analysis of Writings on Beginner and Intermediate Levels”. In it he first presents how to construct such a corpus, and then presents his analysis of grammar errors that a collection of 182 written texts written by Japanese learners contained.
Editors and Editorial Board wish the regular and new readers of the ALA journal a pleasant read full of inspiration.
ALA editorial board(besedilo v angleščini)
Any scientific discipline undoubtedly encounters different challenges in their development over time. However, with the rise of modern technologies, such challenges expanded to new dimensions.
In linguistics, corpus studies have already proven their advantages, and many researchers and other users enjoy the richness of different corpora, spreading enthusiasm and courage to treat linguistics interdisciplinarily. At the same time, minority languages and poorly studied languages are also gaining researchers\u27 attention. Modern technologies further motivated different translation tools, which globalize the world with an enormous speed and seems to dicrease the relevance of language study and foreign language learning. However, the needs for interest in languages remain high. Though perhaps in a different form.
This issue comprises the above ideas in five articles.
Mayuri L. DILIP and Rayesh KUMAR coauthored the article “Clitic or Agreement Restriction in Santali: A Typological Analysis”, in which they investigated the syntactic configuration of pronominal number marking in Santali, the third most-spoken Austroasiatic language, from syntactic, morphological and prosodic perspective.
The following article “Contextual factors and language: an analysis of order placements” was written by Andrej BEKEŠ. It tackles Japanese in a specific social context, namely written ordering requirements on a crowdsourcing website, and reports negative correlation between the level of added value of such requirements and the quality of linguistic expression, comparing it to the Grice’s maxims of conversation.
ITO Hideaki\u27s article “Orthoepic Competence Descriptors in Japanese Language Education: CEFR Levels B1 to C2” overviews the Common European Framework of Reference for Languages (CEFR) and the JF Standard for Japanese-Language Education to discuss the benefits of their merging. In particular, the author re-examines CEFR descriptors for levels B1 to C2 in a non-alphabetically transcribed Japanese, which have not yet been attempted, and combine them with the results for levels A1 and A2 to present descriptors for levels A1 to C2 in overall.
KIM Yu Young in his article “Development and Operation Results of Japanese Accent Perception Test Based On e-learning System” introduced the [AJ-phonetic Test] system, an online tool for practicing perception of Japanese word accent, presented its benefits through a longitudinal study on Korean learners of Japanese.
Finally, Miha PAVLOVIČ wrote an article entitled “Grammar Errors by Slovenian Learners of Japanese: Corpus Analysis of Writings on Beginner and Intermediate Levels”. In it he first presents how to construct such a corpus, and then presents his analysis of grammar errors that a collection of 182 written texts written by Japanese learners contained.
Editors and Editorial Board wish the regular and new readers of the ALA journal a pleasant read full of inspiration.
ALA editorial boar
The malignant stroke indicator is an early indicator of malignant ischemic stroke requiring decompressive hemicraniectomy
Full text linkDecompressive craniectomy (DHC) can prevent mortality in patients with malignant ischemic stroke. However, no clear criteria have been established to early identify patients, who will develop malignant stroke requiring DHC. In this retrospective observational study, a large patient cohort with ischemic stroke treated between 2010 and 2021, was analyzed. Clinical and radiological parameters were analyzed. Univariate and multivariate regression analyses were performed to identify the parameters to be included in the score. A cohort of 534 patients was included. A malignant stroke indicator (MSI) score was created including age < 70 years with 7 points, midline shift with up to 6 points, unsuccessful recanalization (TICI < 2b) with 6 points, basal cistern effacement with 4 points, and CBV ASPECTS < 6 with 3 points assigned. A MSI score with a cutoff value of 9 showed a high discrimination power concerning the need for DHC (AUC 0.90, p < 0.0001). Patients with MSI-score ≥ 9 had a 22-fold higher probability of needing DHC (odds ratio 22.90, p < 0.0001). The MSI score is a promising tool to predict the need for DHC in patients at risk for developing a malignant stroke and needs to be validated in external cohorts
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