124,813 research outputs found
Biochemical protein interactions of Gliotactin at the tricellular junction
No full textThe septate junction is an occluding junction in invertebrates, similar in function to tight
junctions, playing a role in epithelial barriers, and in apical/basal polarity. Septate junction
interactions are still being characterized as new component proteins are discovered. One septate
junction protein, Gliotactin, was discovered in Drosophila to correlate with the mislocalization
of characteristic septate junction proteins in a Gliotactin null animal. However, Gliotactin is the
only component found exclusively at the level of septate junctions at tricellular junctions in
epithelia. The tricellular junctions are the structure at the convergence of three cells and a
potential organizing factor of the septate junction. This led to the question, what is Gliotactin's
role in the organization of the tricellular and septate junctions? To study this, we looked at
Gliotactin interactors, and attempted to elucidate a model of tricellular and septate junction
protein interactions. Previous attempts at finding Gliotactin interactors were made using in vitro
systems or by using transgenic animals using an over-expressed epitope-tagged Gliotactin, that
showed that Gliotactin interacts with known septate junction proteins in a calcium dependent
manner. This thesis aims to further explore Gliotactin interactions with the hypothesis that
native Gliotactin in Drosophila interacts in a calcium dependant manner with septate junction
proteins, Discs Large, and Neurexin IV. Using co-immunoprecipitation and GST pulldowns, on
native Gliotactin protein in Drosophila, I have shown that Gliotactin does not interact with
Neurexin IV but does interact with Discs Large in a calcium-dependent manner. This is
significant in that, to date, there has been no known interactor of Discs Large or of native
Gliotactin at the tricellular junction. I also present data on unidentified potential Gliotactin
interactors seen in a GST pulldown assay. The data presented in this thesis has contributed to a
new working model of the tricellular junction and the role of Gliotactin.Science, Faculty ofZoology, Department ofGraduat
La nueva emigración española. Lo que sabemos y lo que no
No full textLa crisis económica que azota el país desde hace ya seis años no podía dejar de
tener su reflejo demográfico. La población residente en España se ha reducido
en 2013 en más de 50.000 personas. Es la primera vez que esto ocurre desde
que se disponen estadísticas comparables (Cifras de Población, INE 2013). La
inversión del ciclo migratorio tiene mucho que ver en ello. Tras el boom inmigratorio
iniciado en el año 2000 y que supuso un crecimiento medio de 720.000
habitantes en el período 2002-2008, las entradas de extranjeros se fueron ralentizando
desde 2009, a la vez que los flujos de salida se intensificaban. Dichas
salidas han sido protagonizadas por ciudadanos extranjeros, pero el número de
los españoles que se marchan del país no ha dejado de crecer desde 2008 y, en
especial, desde 2011 (Gráfico 1).
De hecho, un 48% de los españoles decían estar dispuestos a trasladarse
a vivir a otro país en el Barómetro del CIS de febrero de 2012, frente a un 30%
de los suecos o el 35% de los alemanes en encuestas similares. Y un 17% confesaba
haber pensado realmente en esa posibilidad en los últimos doce meses.
Las historias de españoles que deciden emprender el camino de la emigración
inundan reportajes periodísticos y programas televisivos desde hace meses. Y
la preocupación por la posible ‘fuga de cerebros’ y sus consecuencias a medio
y largo plazo sobre la economía y el desarrollo de nuestro país son innegables.
En este documento trataremos de poner algo de orden en las cifras, combinando
y contrastando la información que ofrecen nuestras fuentes con las procedentes
de algunos de los destinos principales de la nueva emigración española.
Situaremos la dinámica migratoria española en el contexto de los movimientos
migratorios intra-UE durante la crisis para apreciar mejor su importancia cuantitativa
y cualitativa. Además examinaremos cómo se está modificando el perfil
del emigrante español desde que empezó la crisis y si se trata de una migración
permanente o de corto plazo, en función de las cifras de retorno disponibles.Peer reviewe
QUANTUM-THEORY OF PLASMONS IN LATERAL MULTIWIRE SUPERLATTICES - INTRASUBBAND PLASMONS AND THEIR COUPLING TO INTERSUBBAND PLASMONS
No full textWe analyze intrasubband plasmons in lateral multiwire superlattices and study their coupling to intersubband plasmons. We find that the local approximation is equivalent to neglecting the umklapp contributions to the plasmon energy. While this approximation fails completely for intersubband plasmons, it is reasonable for intrasubband plasmons in the long-wavelength limit. In common with intersubband plasmons, an approximate sum rule exists for intrasubband plasmons, but unlike the case for intersubband plasmons, here it is more precise because it tends to be independent of the details of the confining potential. It is predicted that in a system with n populated subbands, we should observe experimentally only one intrasubband plasmon mode. For zero wave vector along the superlattice direction, intrasubband plasmons only couple to even-parity intersubband plasmons. The coupling of intrasubband plasmons to the dominant intersubband plasmons and other odd-parity intersubband plasmons is very weak in general. Experiments are proposed to verify the importance of Coulomb coupling between wires.Physics, Condensed MatterSCI(E)33ARTICLE97127-71354
Gender and the politics of the gaze in Bronte's Wuthering Heights
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Letras/Inglês e Literatura Correspondente, Florianópolis, 2009.O objetivo deste estudo é apresentar uma análise de como a imagem de Catherine é moldada pelo olhar masculino, como ela enfrenta os três tipos de olhar - o olhar dos personagens, o olhar do leitor, e o olhar do autor - e finalmente, se o olhar masculino é interrompido. O parâmetro teórico desta análise, o conceito do olhar masculino, é teorizado por Laura Mulvey no artigo "Prazer Visual e Cinema Narrativo" (1975) o qual critica a relação entre o olhar masculino e a imagem feminina do prazer visual moldado pela sociedade patriarcal. Através da crítica de Mulvey do prazer visual generizado em filmes, que pertence ao contexto do cinema clássico de Hollywood, articulo sua teoria em relação ao romance Wuthering Heights de Emily Brontë para examinar a dinâmica do olhar masculino em relação à personagem feminina Catherine. Este estudo teve também por objetivo analisar o quanto o paradigma teórico de Mulvey produzido para cinema poderia ser aplicado especificamente em um texto literário escrito no século XIX.The objective of this thesis is to present an analysis of whether Catherine's image has been shaped by the male gaze, how she contends with the three looks of the male gaze - the look of the characters, the look of the reader, and the look of the author - and finally, how the male gaze is broken. The theoretical parameter of this analysis, the concept of the male gaze, is theorized by Laura Mulvey in the article "Visual Pleasure and Narrative Cinema" (1975) which critiques the relation between the male gaze and the female image within the patriarchal molding of visual pleasure. Borrowing Mulvey's critique of the gendering of visual pleasure in films, which pertains to the context of classical Hollywood cinema, I have articulated her theory in relation to Emily Brontë's Wuthering Heights, to examine the dynamics of the male gaze regarding the female character, Catherine. This study also aimed at examing the extent to which Mulvey's theoretical paradigm produced for cinema could be articulated specifically in relation to a literary text written in the nineteenth century
Calciumcarbonaatfabriek
No full textDocument(en) uit de collectie Chemische ProcestechnologieDelftChemTechApplied Science
Hou Renzhi, 1911-2013 Obituary
No full texthttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330909100014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701GeographyHistory Of Social [email protected]
Carta sobre un cajoncito que contiene prendas indígenas, 1776 enero 20
No full textCarta a Junípero Serra en la que se reconoce que aún no se ha recibido un cajoncito con prendas de indígenas recién descubiertos. El autor asegura a Serra que le avisará cuando lo reciba y expresa su gratitud por la fina memoria. —— Letter to Junípero Serra acknowledging that they have not yet received a small box containing garments of newly encountered Indigenous people. The author assures Serra that they will notify them upon receipt and expresses gratitude for the thoughtful remembrance. 1 f. (2 p.
Exploring the Evolution of Passenger Characteristics Based on Smart Card Data: A Case Study of Shenzhen, China
No full textPassenger travel characteristics (PTCs) are characteristics that are sought from the information contained in trips, such as travel frequency, travel mode, departure location, and etc. Understanding PTCs can help develop passenger-oriented planning and service policies, so analysis of PTCs is a topic of constant interest to researchers and transportation service providers. However, PTCs vary with the change of many factors, such as network, price policy, service. The process or trend of PTCs change, which is called the evolution of PTCs, are useful for assessing the impact of external factors changes on passengers.Transport, Infrastructure and Logistic
Propiedades psicométricas del inventario de violencia en las relaciones de pareja en los adolescentes (CADRI) del distrito de Salaverry-Trujillo
No full textLa presente investigación tiene como propósito presentar los resultados alcanzados
en el análisis de las Propiedades Psicométricas del Inventario de violencia en las
relaciones de pareja en los adolescentes (CADRI) del distrito de Salaverry-Trujillo,
cuya población estuvo conformada por 249 estudiantes de 15-19 años de edad de
6 Instituciones Educativas del Distrito de Salaverry, que mantenían o hayan
mantenido hasta hace 1 año atrás una relación de pareja. Se determinó la validez
de contenido bajo el criterio de 7 expertos, mostrando índices de .81 a 1.0. Mediante
correlación ítem total e ítem factor corregido se evidenció índices de homogeneidad
corregidos mediante el coeficiente de correlación de Pearson para el ítem y el total
con resultados de .18 y .59 en violencia cometida y de .21 y .69 para de violencia
sufrida. Para la confiabilidad se utilizó el método de consistencia interna mediante
el método alfa de Cronbach, observándose los totales de violencia cometida (.84;
IC: .81 -.87) y sufrida (.88; IC: .86 -.90) y una confiabilidad entre .52 y .79 en los
factores de violencia cometida y entre .53 y .82 en los factores de violencia sufrida.
Finalmente, se desarrollaron normas para la variable Violencia Cometida,
generales en los factores Violencia Relacional y Amenazas; para Violencia Sexual,
Verbal Emocional, Física y variable total, denotan diferencias por género. En
violencia Sufrida, baremos específicos sólo para el factor violencia física
Application of KinectTM and wireless technology for patient data recording and viewing system in the course of surgery
No full textIn modern operating room (OR) conditions, a patient\u27s computed tomography (CT) or magnetic resonance imaging (MRI) scans are some of the most important resources during surgical procedures. In practice, the surgeon is impelled to scrub out and back in every time he needs to scroll through scan images in mid-operation. To prevent leaving the operating table, many surgeons rely on assistants or nurses and give instructions to manipulate the computer for them, which can be cumbersome and frustrating. As a motivation for this study, the use of touchless (non-contact) gesture-based interface in medical practice is incorporated to have aseptic interactions with the computer systems and with the patient\u27s data. The system presented in this paper is composed of three main parts: the Trek Ai-Ball Camera, the Microsoft Kinect™, and the computer software. The incorporation of these components and the developed software allows the user to perform 13 hand gestures, which have been tested to be 100 percent accurate. Based on the results of the tests performed on the system performance, the conclusions made regarding the time efficiency of the viewing system, the quality and the safety of the recording system has gained positive feedback from consulting doctors. © 2017 Author(s)
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