340 research outputs found
Biology, fisheries and culture of tropical groupers and snappers
Get PDFGroupers and snappers are important fishery resources of the tropics and subtropics, where their high values have caused most of their stocks to be heavily exploited, some even to the point of collapse. Trends towards heavy demand and decreasing natural supply, which are accelerating in several parts of the world, prompted various mariculture ventures. Focused research on biology and the population dynamics of groupers and snappers, and on their reproduction and growth under controlled condition will remain essential for dealing with the questions on how to better manage their fisheries. This volume of papers presents important scientific findings and views on these two important groups of fish.Percoid fisheries, Fishery biology, Fishery management, Conferences
Evaluation of enhanced coalescing strategies for the recovery of stabilized oil droplets in the production of advanced biofuels
No full textConfidential thesis. Abstract only.Mechanical Engineering | Sustainable Process & Energy Technolog
Gait Variability and Kinematic Alterations in People with Diabetes Mellitus and Peripheral Neuropathy
No full textBackground: People with diabetes and peripheral neuropathy have been reported to show alterations in lower limb joint function compared to healthy non-diabetic people. Specifically the maximum angular movement available at certain joints can be reduced during static, non-weight bearing tasks. Limited joint range of motion has the potential to compromise balance and stability thereby increasing the risk of falling. It is unclear whether a reduction in the extent of movement available at the joints is reflected by a reduction in the amount of angular movement actually utilised during a functional task such as stair negotiation. The aim of this study was to determine if people with diabetes show reduced dynamic range of motion at the ankle, knee and hip joints during stair ascent and descent in comparison to controls. Falls risk during stair negotiation was calculated by measuring the degree of variability in dynamic joint range of motion. Methods: Data were generated from three groups: subjects with diabetes and peripheral neuropathy (DPN), diabetes without peripheral neuropathy (DM), and healthy controls (Ctl). The study was conducted in a gait laboratory using motion capture and related 3D software for analysis. Joint range of motion for the ankle, knee, and hip were captured during level walking, stair ascent, and descent. A seven step, bespoke staircase was fabricated for this purpose. Analysis of Variance (ANOVA) and Newman-Keuls tests were used to analyse the data. Results: Significantly reduced ankle range of motion, in the sagittal plane, was observed in the DPN group during stair ascent when compared to the controls. For stair descent, the DPN group demonstrated a significant increase in knee and hip ROM in the frontal plane, and also hip ROM in the transverse plane. No significant differences between the groups were identified for joint variability. Conclusions: People with DPN demonstrate alterations in dynamic range of motion at the lower limb joints during stair ascent and descent. The degree of angular movement utilised for both stair tasks was decreased at the ankle joint and this has the potential to undermine balance and stability. In contrast, angular movement at the knee and hip joints was increased in the frontal and transverse planes. This may compensate for impaired balance and stability by increasing the base of support to maintain balance and assist in foot clearance and placement. The specific combination of increased angular movement at the knee and hip may represent a compensatory stair gait strategy in response to reduced angular movement at the ankle joint
MIGRATORY AND RESIDENT WILD BIRDS AND THEIR ROLE IN THE TRANSMISSION OF Rickettsia spp. IN TICKS (ACARI: IXODIDAE) IN THE DEPARTMENT OF CALDAS
No full textMapas, ilustracionesspa: Las aves silvestres han sido relacionadas con el transporte y dispersión de garrapatas duras entre y
dentro de los continentes. Así mismo, al parecer juegan un papel clave en la epidemiología de los
patógenos asociados con las garrapatas. Principalmente se ha documentado el papel de las aves en
la diseminación de garrapatas duras de origen Neotropical, en algunos casos portadoras de bacterias
patógenas en América (e.g., Borrelia, Ehrlichia y Rickettsia). En Colombia se ha registrado la
presencia de rickettsias en garrapatas, mamíferos silvestres, domésticos, y en humanos, pero se
desconoce el rol de las aves como hospederos de garrapatas portadoras de bacterias de este género.
El departamento de Caldas parece ser un escenario propicio para investigar las relaciones entre
aves, garrapatas y rickettsias, debido a los registros de casos de Rickettsia en humanos en 2005. En
la presente investigación, se realizó la búsqueda de garrapatas duras en aves silvestres en 19
municipios del departamento de Caldas. Las garrapatas colectadas de las aves se examinaron e
identificaron con claves taxonómicas con base en su morfología y análisis moleculares con los
genes 16S, COI e ITS2. Posteriormente, para la detección de Rickettsia en las garrapatas se
utilizaron los genes gltA, ompA y ompB. Se examinaron 2314 aves, de las cuales 78 individuos
(3,4%) resultaron infestados por garrapatas. Diez especies de garrapatas se colectaron en aves
(Amblyomma longirostre, Amblyomma varium, Amblyomma dissimile, Amblyomma ovale,
Amblyomma nodosum, Amblyomma calcaratum, Ixodes sp. I, Ixodes sp. II, Ixodes sp III y
Haemaphysalis leporispalustris). Se detectó la presencia de Rickettsia amblyommatis, Rickettsia
sp. cepa Koreansis, Candidatus Rickettsia tarasevichiae/Rickettsia canadensis, Candidatus
Rickettsia colombianensi/Rickettsia monacensis y Rickettsia sp. en cinco de las especies de
garrapatas mencionadas. Se reportan nuevas asociaciones entre aves y garrapatas, principalmente
entre aves migratorias boreales y garrapatas de origen Neotropical. Finalmente, se discute la
importancia de las aves como hospederos de garrapatas infectadas por rickettsias.eng: Wild birds are associated with hard tick transport and dispersal between and within continents. Furthermore, birds play a key role in the epidemiology of tick-borne pathogens. There is documented information on the role of birds in the dispersal of Neotropical hard ticks, which, in some cases, transmit pathogenic bacteria in America (e.g., Borrelia, Ehrlichia, and Rickettsia). In Colombia, there are records of rickettsiae in ticks, wild and domestic mammals, and humans; however, the role of birds as hosts of ticks that carry rickettsiae is unknown. The department of Caldas is an ideal setting to study the relationships among birds, ticks, and rickettsiae, due to case reports of Rickettsia en humans in 2005. This research studied hard ticks from wild birds in 19 municipalities in the department of Caldas. The collected ticks were examined and morphologically identified using taxonomic keys. Molecular analyses of 16S, COI, and ITS2 gene sequences were also performed for tick identification. The detection of tick-borne Rickettsia was done using genes gltA, ompA, and ompB. A total of 2314 birds were examined, including 78 individuals (3.4%) that were infested with ticks. Ten tick species were collected and identified (e.g. Amblyomma longirostre, Amblyomma varium, Amblyomma dissimile, Amblyomma ovale, Amblyomma nodosum, Amblyomma calcaratum, Ixodes sp. I, Ixodes sp. II, Ixodes sp III, and Haemaphysalis leporispalustris). The presence of Rickettsia amblyommatis, Rickettsia sp. strain Koreansis, Candidatus Rickettsia tarasevichiae/Rickettsia canadensis, Candidatus Rickettsia colombianensi/Rickettsia monacensis, and Rickettsia sp. was detected in five tick species. New associations between birds and ticks are reported, mainly between migratory boreal and Neotropical ticks. Finally, the importance of birds as hosts of rickettsia-infected ticks is discussed.1. INTRODUCTORY CHAPTER/ 11 2. MATERIALS AND METHODS/ 14 2.1. Study area / 14 2.2. Bird capture, collection and morphological identificaction of ticks/ 14 2.3. Molecular identification of ticks and Ricketsia spp. Detection /15 3. RESULTS/ 17 3.1. CHAPTER I Associations between wild birds and hard ticks (Acari: Ixodidae) in Colombia/ 18 3.2. CHAPTER II Rickettsia spp. in ticks (Acari: Ixodidae) from wild birds in Caldas, Colombia/ 4. FINAL CONSIDERATIONS / 5. REFERENCESMaestríaMagister en Ciencias Biológica
RAS polymorphisms in cancerous and benign breast tissue
No full textRecent information has revealed new roles in the angiogenic processes linked to the rennin-angiotensin system. To date few studies have been done on the association between RAS genes and cancer and the majority focus mainly on angiotensin I-converting enzyme (ACE). For breast cancer there are three reports that include the angiotensin II receptor, subtype 1 (AGTR1), only one for angiotensinogen (AGT) and none for renin gene (REN). In the present study we investigate whether REN (BglI), AGT (M235T), ACE (A245T, Indel), and AGTR1 (A1166C) are associated with breast cancer. Polymorphisms were analysed by PCR and RFPLs or sequence specific assay in three groups: breast cancer, benign breast disease (BBD) and general population. REN polymorphism shows that homozygous for A allele have an increased risk for BBD. Differences in M235T genotype frequencies were significant with less heterozygous in breast cancer. With different risk values ACE indel was associated with BBD and breast cancer. Association of AGTR1 was observed only in the breast cancer group, where C allele carriers present a reduced risk. Results of this work supports previous observations on the possible involvement of this system in breast cancer but it also suggests a role in benign disease. © The Author(s) 2010
Author correction: common variants in alzheimer’s disease and risk stratification by polygenic risk scores (nature communications, (2021), 12, 1, (3417), 10.1038/s41467-021-22491-8)
No full textde Rojas I., Moreno-Grau S., Tesi N., Grenier-Boley B., Andrade V., Jansen I.E., Pedersen N.L., Stringa N., Zettergren A., Hernández I., Montrreal L., Antúnez C., Antonell A., Tankard R.M., Bis J.C., Sims R., Bellenguez C., Quintela I., González-Perez A., Calero M., Franco-Macías E., Macías J., Blesa R., Cervera-Carles L., Menéndez-González M., Frank-García A., Royo J.L., Moreno F., Huerto Vilas R., Baquero M., Diez-Fairen M., Lage C., García-Madrona S., García-González P., Alarcón-Martín E., Valero S., Sotolongo-Grau O., Ullgren A., Naj A.C., Lemstra A.W., Benaque A., Pérez-Cordón A., Benussi A., Rábano A., Padovani A., Squassina A., de Mendonça A., Arias Pastor A., Kok A.A.L., Meggy A., Pastor A.B., Espinosa A., Corma-Gómez A., Martín Montes A., Sanabria Á., DeStefano A.L., Schneider A., Haapasalo A., Kinhult Ståhlbom A., Tybjærg-Hansen A., Hartmann A.M., Spottke A., Corbatón-Anchuelo A., Rongve A., Borroni B., Arosio B., Nacmias B., Nordestgaard B.G., Kunkle B.W., Charbonnier C., Abdelnour C., Masullo C., Martínez Rodríguez C., Muñoz-Fernandez C., Dufouil C., Graff C., Ferreira C.B., Chillotti C., Reynolds C.A., Fenoglio C., Van Broeckhoven C., Clark C., Pisanu C., Satizabal C.L., Holmes C., Buiza-Rueda D., Aarsland D., Rujescu D., Alcolea D., Galimberti D., Wallon D., Seripa D., Grünblatt E., Dardiotis E., Düzel E., Scarpini E., Conti E., Rubino E., Gelpi E., Rodriguez-Rodriguez E., Duron E., Boerwinkle E., Ferri E., Tagliavini F., Küçükali F., Pasquier F., Sanchez-Garcia F., Mangialasche F., Jessen F., Nicolas G., Selbæk G., Ortega G., Chêne G., Hadjigeorgiou G., Rossi G., Spalletta G., Giaccone G., Grande G., Binetti G., Papenberg G., Hampel H., Bailly H., Zetterberg H., Soininen H., Karlsson I.K., Alvarez I., Appollonio I., Giegling I., Skoog I., Saltvedt I., Rainero I., Rosas Allende I., Hort J., Diehl-Schmid J., Van Dongen J., Vidal J.-S., Lehtisalo J., Wiltfang J., Thomassen J.Q., Kornhuber J., Haines J.L., Vogelgsang J., Pineda J.A., Fortea J., Popp J., Deckert J., Buerger K., Morgan K., Fließbach K., Sleegers K., Molina-Porcel L., Kilander L., Weinhold L., Farrer L.A., Wang L.-S., Kleineidam L., Farotti L., Parnetti L., Tremolizzo L., Hausner L., Benussi L., Froelich L., Ikram M.A., Deniz-Naranjo M.C., Tsolaki M., Rosende-Roca M., Löwenmark M., Hulsman M., Spallazzi M., Pericak-Vance M.A., Esiri M., Bernal Sánchez-Arjona M., Dalmasso M.C., Martínez-Larrad M.T., Arcaro M., Nöthen M.M., Fernández-Fuertes M., Dichgans M., Ingelsson M., Herrmann M.J., Scherer M., Vyhnalek M., Kosmidis M.H., Yannakoulia M., Schmid M., Ewers M., Heneka M.T., Wagner M., Scamosci M., Kivipelto M., Hiltunen M., Zulaica M., Alegret M., Fornage M., Roberto N., van Schoor N.M., Seidu N.M., Banaj N., Armstrong N.J., Scarmeas N., Scherbaum N., Goldhardt O., Hanon O., Peters O., Skrobot O.A., Quenez O., Lerch O., Bossù P., Caffarra P., Dionigi Rossi P., Sakka P., Mecocci P., Hoffmann P., Holmans P.A., Fischer P., Riederer P., Yang Q., Marshall R., Kalaria R.N., Mayeux R., Vandenberghe R., Cecchetti R., Ghidoni R., Frikke-Schmidt R., Sorbi S., Hägg S., Engelborghs S., Helisalmi S., Botne Sando S., Kern S., Archetti S., Boschi S., Fostinelli S., Gil S., Mendoza S., Mead S., Ciccone S., Djurovic S., Heilmann-Heimbach S., Riedel-Heller S., Kuulasmaa T., del Ser T., Lebouvier T., Polak T., Ngandu T., Grimmer T., Bessi V., Escott-Price V., Giedraitis V., Deramecourt V., Maier W., Jian X., Pijnenburg Y.A.L., Smith A.D., Saenz A., Bizzarro A., Lauria A., Vacca A., Solomon A., Anastasiou A., Richardson A., Boland A., Koivisto A., Daniele A., Greco A., Marianthi A., McGuinness B., Fin B., Ferrari C., Custodero C., Ferrarese C., Ingino C., Mangone C., Reyes Toso C., Martínez C., Cuesta C., Muchnik C., Joachim C., Ortiz C., Besse C., Johansson C., Zoia C.P., Laske C., Anastasiou C., Palacio D.L., Politis D.G., Janowitz D., Craig D., Mann D.M., Neary D., Jürgen D., Daian D., Belezhanska D., Kohler E., Castaño E.M., Koutsouraki E., Chipi E., De Roeck E., Costantini E., Vardy E.R.L.C., Piras F., Roveta F., Piras F., Prestia F.A., Assogna F., Salani F., Sala G., Lacidogna G., Novack G., Wilcock G., Thonberg H., Kölsch H., Weber H., Boecker H., Etchepareborda I., Piaceri I., Tuomilehto J., Lindström J., Laczo J., Johnston J., Deleuze J.-F., Harris J., Schott J.M., Priller J., Bacha J.I., Snowden J., Lisso J., Mihova K.Y., Traykov L., Morelli L., Brusco L.I., Rainer M., Takalo M., Bjerke M., Del Zompo M., Serpente M., Sanchez Abalos M., Rios M., Peltonen M., Herrman M.J., Kohler M., Rojo M., Jones M., Orsini M., Medel N., Olivar N., Fox N.C., Salvadori N., Hooper N.M., Galeano P., Solis P., Bastiani P., Passmore P., Heun R., Antikainen R., Olaso R., Perneczky R., Germani S., López-García S., Love S., Mehrabian S., Bagnoli S., Kochen S., Andreoni S., Teipel S., Todd S., Pickering-Brown S., Natunen T., Tegos T., Laatikainen T., Strandberg T., Polvikoski T.M., Matoska V., Ciullo V., Cores V., Solfrizzi V., Lisetti V., Sevillano Z., Aguilera N., Alarcon E., Alegret M., Boada M., Buendia M., Cañabate P., Carracedo A., de Rojas I., Diego S., Espinosa A., Gailhajenet A., García-González P., Gil S., Guitart M., González-Pérez A., Hernández I., Ibarria M., Lafuente A., Macias J., Maroñas O., Martín E., Martínez M.T., Marquié M., Mauleón A., Moreno-Grau S., Moreno M., Orellana A., Ortega G., Pancho A., Pelejá E., Pineda J.A., Preckler S., Quintela I., Real L.M., Rosende-Roca M., Ruiz A., Sáez M.E., Sanabria A., Serrano-Rios M., Tárraga L., Valero S., Vargas L., Adarmes-Gómez A.D., Alonso M.D., Álvarez I., Álvarez V., Amer-Ferrer G., Antequera M., Antúnez C., Baquero M., Bernal M., Blesa R., Bullido M.J., Burguera J.A., Calero M., Carrillo F., Carrión-Claro M., Casajeros M.J., Clarimón J., Cruz-Gamero J.M., de Pancorbo M.M., de Rojas I., del Ser T., Diez-Fairen M., Escuela R., Garrote-Espina L., Fortea J., García-Alberca J.M., Garcia-Ribas G., Gómez-Garre P., Hevilla S., Jesús S., Labrador Espinosa M.A., 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Á., Amouyel P., Schellenberg G.D., Williams J., Seshadri S., van Duijn C.M., Mather K.A., Sánchez-Valle R., Serrano-Ríos M., Orellana A., Tárraga L., Blennow K., Huisman M., Andreassen O.A., Posthuma D., Clarimón J., Boada M., van der Flier W.M., Ramirez A., Lambert J.-C., van der Lee S.J., Ruiz A
A submarine volcanic eruption leads to a novel microbial habitat
Get PDFSubmarine volcanic eruptions are major catastrophic events that allow investigation of the colonization mechanisms of newly formed seabed. We explored the seafloor after the eruption of the Tagoro submarine volcano off El Hierro Island, Canary Archipelago. Near the summit of the volcanic cone, at about 130 m depth, we found massive mats of long, white filaments that we named Venus’s hair. Microscopic and molecular analyses revealed that these filaments are made of bacterial trichomes enveloped within a sheath and colonized by epibiotic bacteria. Metagenomic analyses of the filaments identified a new genus and species of the order Thiotrichales, Thiolava veneris. Venus’s hair shows an unprecedented array of metabolic pathways, spanning from the exploitation of organic and inorganic carbon released by volcanic degassing to the uptake of sulfur and nitrogen compounds. This unique metabolic plasticity provides key competitive advantages for the colonization of the new habitat created by the submarine eruption. A specialized and highly diverse food web thrives on the complex three-dimensional habitat formed by these microorganisms, providing evidence that Venus’s hair can drive the restart of biological systems after submarine volcanic eruption
Reactivity of 3-sulfanyl-1-hexanol and catechol-containing phenolics in vitro
No full textLaurie, VF (reprint author), Univ Talca, Sch Agr Sci, 2 Norte 685, Talca, Chile.Volatile species with thiol functions are important contributors to the flavour of a wide variety of wine types. However, in spite of their importance, their fate during winemaking has not been fully elucidated. In this work, the iron-catalysed reaction between 3-sulfanyl-1-hexanol, catechol-containing phenolics, and sulfurous acid, under in vitro aerobic conditions was evaluated by means of electrospray ionisation mass spectrometry (ESI-MS). The results indicate that a direct addition reaction between the thiol and some of the phenolics tested, and between sulfite and some of the phenolics may occur, thus contributing evidence of a possible route of thiol losses in wines. (C) 2011 Elsevier Ltd. All rights reserved
Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores (Nature Communications, (2021), 12, 1, (3417), 10.1038/s41467-021-22491-8)
No full textThe original version of this Article omitted from the author list the 212th author Patrizia Mecocci, who is from the Institute of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy. Consequently, the “Sample Contribution” section of Author Contributions was updated to add “P.M” between “P.D.” and “R.C.”. Additionally, the original version of this Article contained the incorrect affiliation for author Patrick Gavin Kehoe, which incorrectly read “German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany”. The correct version replaces this affiliation with “Bristol Medical School (THS), University of Bristol, Southmead Hospital, Bristol, UK”. This has been corrected in both the PDF and HTML versions of the Article. © The Author(s) 2023
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
Get PDFWe conducted a multi-stage, genome-wide association study of bladder cancer with a primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of European descent from five studies followed by a replication strategy, which included 8,382 cases and 48,275 controls from 16 studies. In a combined analysis, we identified three new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1: rs1014971, (P = 8 × 10⁻¹²) maps to a non-genic region of chromosome 22q13.1, rs8102137 (P = 2 × 10⁻¹¹) on 19q12 maps to CCNE1 and rs11892031 (P = 1 × 10⁻⁷) maps to the UGT1A cluster on 2q37.1. We confirmed four previously identified genome-wide associations on chromosomes 3q28, 4p16.3, 8q24.21 and 8q24.3, validated previous candidate associations for the GSTM1 deletion (P = 4 × 10⁻¹¹) and a tag SNP for NAT2 acetylation status (P = 4 × 10⁻¹¹), and found interactions with smoking in both regions. Our findings on common variants associated with bladder cancer risk should provide new insights into the mechanisms of carcinogenesis
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