63 research outputs found
The Smith–Lemli–Opitz syndrome: a novel metabolic way of understanding developmental biology, embryogenesis, and dysmorphology
No full textRecommended from our members
Coordinating CZARA and 319; author notes on webinar
No full textAuthor's notes for each slide from presentation from a May 2013 webinar for the Coastal States Organization that explains how EPA’s FY2014 Clean Water Act Section 319 Nonpoint Source Program and Grants Guidelines for States and Territories affects states with coastal nonpoint pollution control programs under Coastal Zone Act Reauthorization Amendments (CZARA) and what EPA’s expectations are for coordinating these complementary state programs
Wayo Waye
No full textReggae and jazz influenced dance music rooted in Sengalese mbalax frenetic and syncopated rhythm
Trading in legal claims: law, policy and future directions in Australia, UK and US
No full textThis book analyses law and policy issues regarding the creation of markets for trading in legal claims. The author reviews the current positions in Australia, UK and US regarding claim alienability and provides a comparative analysis of the divergent paths that have developed in each, all of which portend towards claim commodification. The author also examines the regulatory options to ensure that claim holders in a legal claim market would be protected from exploitation and that the market operates fairly and efficiently. The book reviews costs and abuse of process issues that could arise and conflicts of interest that may exist between claimholders, lawyers and entrepreneurs. The author argues that legal claim markets are justified on both policy and efficiency grounds as a means of improving access to justice
Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction
No full textNon-isotopic in situ hybridization of chromosome-specific alphoid DNA probes has become a potent tool in the study of numerical aberrations of specific human chromosomes at all stages of the cell cycle. In this paper, we describe approaches for the rapid generation of such probes using the polymerase chain reaction (PCR), and demonstrate their chromosome specificity by fluorescence in situ hybridization to normal human metaphase spreads and interphase nuclei. Oligonucleotide primers for conserved regions of the alpha satellite monomer were used to generate chromosome-specific DNA probes from somatic hybrid cells containing various human chromosomes, and from DNA libraries from sorted human chromosomes. Oligonucleotide primers for chromosome-specific regions of the alpha satellite monomer were used to generate specific DNA probes for the pericentromeric heterochromatin of human chromosomes 1, 6, 7, 17 and X directly from human genomic DNA
Judicial fact finding: trial by judge alone in serious criminal cases
No full textThe ability to choose between trial by jury and trial by judge alone in some jurisdictions presupposes a rational basis for exercising the choice. In this article, the author examines judicial factfinding modalities from comparative and systemic perspectives. The conclusion drawn is that both judicial fact-finders and lay fact-finders process their decision-making similarly. In both instances, fact-finding involves the assimilation of disparate and sometimes complex information. In each case, the drawing of inferences is, of necessity, dependent upon heuristic reasoning. Furthermore, the application of principles of law to proven facts is inexact. However, there are a number of inbuilt safeguards in judicial fact-finding that promote rationality and inhibit cognitive illusion.Vicki Way
Authorship in the Interstices of History, Biography, Reality and Memory: Histoire(s) du cinéma and Cabra Marcado para Morrer
No full textEste artigo contrasta Histoire(s) du cinéma de Jean-Luc Godard e Cabra Marcado Para Morrer de Eduardo Coutinho, estão engajadas com a questão da autoria no cinema. Enquanto a imagem de Godard enfatiza a capacidade que tem um filme de transmitir a visão de mundo pessoal de um artista, a presença de Coutinho na tela funciona menos como um meio de subjetivar a obra do que como um catalizador instigando cetas reações nos "atores" filmados
Specific loss of chromosomes 1, 2, 6, 10, 13, 17, and 21 in chromophobe renal cell carcinomas revealed by comparative genomic hybridization
No full textWe analyzed 19 chromophobe renal cell carcinomas by means of comparative genomic hybridization. Two tumors revealed no numerical abnormalities. In the remaining 17 cases we found loss of entire chromosomes with underrepresentation of chromosome 1 occurring in all 17 cases; loss of chromosomes 2, 10, and 13 in 16 cases; loss of chromosomes 6 and 21 in 15 tumors; and loss of chromosome 17 in 13 cases. The loss of the Y chromosome was observed in 6 of 13 tumors from male patients, whereas 1 X chromosome was lost in 3 of 4 tumors obtained from females. Comparative genomic hybridization results were verified by interphase cytogenetics. We conclude that a specific combination of multiple chromosomal losses characterizes chromophobe renal cell carcinomas and may help to differentiate them unequivocally from other types of kidney cancer
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