293 research outputs found
Testing of tungsten coatings in JET for the ITER-like wall
No full textA CFC tile 5 from the JET outer divertor, and CFC tiles from neutral beam shine-through and re-ionisation regions were coated with tungsten and exposed during the 2005-7 JET campaigns in preparation for the ITER-like wall project. Approximately 1.6 microns of coating were eroded from the tile 5 during high-delta discharges when the outer strike-point is on the tile. The coatings on the other tiles were unaffected by NB-heating and divertor discharges, however a tile mounted near the centre of the Inner Wall Guard Limiter lost all its coating from the surface within 10 mm of the tile leading edge; this probably occurred during the ramp-up phase of JET discharges. (C) 2009 J.P. Coad. Published by Elsevier B.V. All rights reserved
Material migration and fuel retention studies during the JET carbon divertor campaigns
No full textThe first divertor was installed in the JET machine between 1992 and 1994 and was operated with carbon tiles and then beryllium tiles in 1994–5. Post-mortem studies after these first experiments demonstrated that most of the impurities deposited in the divertor originate in the main chamber, and that asymmetric deposition patterns generally favouring the inner divertor region result from drift in the scrape-off layer. A new monolithic divertor structure was installed in 1996 which produced heavy deposition at shadowed areas in the inner divertor corner, which is where the majority of the tritium was trapped by co-deposition during the deuterium-tritium experiment in 1997. Different divertor geometries have been tested since such as the Gas-Box and High-Delta divertors; a principle objective has been to predict plasma behaviour, transport and tritium retention in ITER. Transport modelling experiments were carried out at the end of four campaigns by puffing 13C-labelled methane, and a range of diagnostics such as quartz-microbalance and rotating collectors have been installed to add time resolution to the post-mortem analyses. The study of material migration after D-D and D-T campaigns clearly revealed important consequences of fuel retention in the presence of carbon walls. They gave a strong impulse to make a fundamental change of wall materials. In 2010 the carbon divertor and wall tiles were removed and replaced with tiles with Be or W surfaces for the ITER-Like Wall Project
Using art-based techniques in engaging children and young people in health care consultations and/or research
No full textThis paper outlines how art-based techniques and activities can applied for use in consultation work and/or research projects with children and young people. First, the concept of what constitutes an art-based activity and how it might be used in consultation and/or research is explored. Following this, three art-based activities of using photographs, drawings/posters or collages and mapping techniques are considered in terms of application to field work. Literature and work undertaken by the author is drawn upon. Critical discussion of using art-based techniques includes pragmatic discussion relating to entering the field, time, resources, collecting the data, settings and feedback
Cross-artform creative practice as still-life recovery: Chinese-Western materialisms of time, writing and death
No full textAs argued by Norman Bryson, the still-life genre is sorely neglected by theorists and critics, largely because its concern with ‘low-plane reality’ (everyday items and acts) has obscured its genuine relevance to material thinking. By reappraising rather than abandoning the genre’s traditional themes of death and time—using a cross-cultural, Chinese-Western approach—it is possible to re-energise materialisms of time, writing and death within still life. Such a move depends above all on a re-evaluation of still life as ‘Vanitas’—the term which to date has unified, and more to the point limited, traditional still-life understandings of death and time. This article tracks a more explosive and creative materialism of still life simultaneously through the specifically Chinese approach to death (which includes the ‘Yin Yang’ 阴阳 as a sort of author of time) and via Gilles Deleuze’s cinematic philosophy of the time-image; what connects these is the very Deleuzean notion of time that subtends Chinese engagements with death. In this way, the still-life genre may be recovered from its current critical and theoretical malaise. Reconnecting with practice is a crucial aspect of this recovery, and so in its early stages this article analyses an example of still-life, creative non-fiction (authored by Cher Coad), and it concludes by establishing the value of this potentially ‘new chapter of the “still life” genre’ (in Matilde Marcolli’s terms) for the cross-artform analysis of the short story ‘Nhill’ (authored by Patrick West). Analysis, though, is only half the picture: a fully recovered still-life genre would see theory and practice endlessly circulating through each other, spurring on practice and impelling theory. Coad’s and West’s literary examples are introduced in the hope that they might trigger fresh theoretical and practice-based, still-life discoveries in prose and also in poetry
Exploring the processes of firm growth: evidence from a vector auto-regression
No full textThis article offers many new insights into the processes of firm growth by applying a vector autoregression model to longitudinal panel data on French manufacturing firms. We observe the coevolution of key variables such as growth of employment, sales, gross operating surplus, and labor productivity growth. Preliminary results suggest that employment growth is succeeded by the growth of sales, which in turn is followed by growth of profits. Generally speaking, however, growth of profits is not followed by much employment growth or sales growth. Quantile regressions highlight some asymmetries between negative-growth and fast-growth firms. Copyright 2010 The Author 2010. Published by Oxford University Press on behalf of Associazione ICC. All rights reserved., Oxford University Press.
Building Resilience Through Listening to Children and Young People About Their Health Preferences Using Arts-Based Methods
No full textThis chapter describes how arts-based approaches can be used in effectively eliciting the views children and young people in a range of settings to elicit information about their health preferences. Firstly, it will include what is meant by arts-based approaches and how they might be used in practice. Following this, a number of arts-based activities are considered in terms of applicability for children and young people across three broad groups. Literature and field work undertaken by the author is drawn upon to inform critical discussion of not only using arts-based approaches with children and young people in real world settings but how they can be used to positively impact on children’s resilience and well-being
Integration analysis of long non-coding RNA (lncRNA) role in tumorigenesis of colon adenocarcinoma
No full textBackground: Colon adenocarcinoma (COAD) is one of the most common gastrointestinal cancers globally. Molecular aberrations of tumor suppressors and/or oncogenes are the main contributors to tumorigenesis. However, the exact underlying mechanisms of COAD pathogenesis are clearly not known yet. In this regard, there is an urgent need to indicate promising potential diagnostic and prognostic biomarkers in COAD patients. Methods: In the current study, level 3 RNA-Seq and miR-Seq data and corresponding clinical data of colon adenocarcinoma (COAD) were retrieved from the TCGA database. The "limma"package in R software was utilized to indicate the differentially expressed genes. For in silico functional analysis, GO and KEGG signaling pathways were conducted. PPI network was constructed based on the STRING online database by Cytoscape 3.7.2. A ceRNA network was also constructed by "GDCRNATools"package in R software. Kaplan-Meier survival analysis (log-rank test) and ROC curve analysis were used to indicate the diagnostic and prognostic values of the biomarkers. Results: The differential expression data demonstrated that 2995 mRNAs, 205 lncRNAs, and 345 miRNAs were differentially expressed in COAD. The GO and KEGG pathway analysis indicated that the differentially expressed mRNAs were primarily enriched in canonical processes in cancer. The PPI network showed that the CDKN2A, CCND1, MYC, E2F, CDK4, BRCA2, CDC25B, and CDKN1A proteins were the critical hubs. In addition, the Kaplan-Meier analysis revealed that 215 mRNAs, 14 lncRNAs, and 39 miRNAs were associated with overall survival time in the patients. Also, the ceRNA network data demonstrated that three lncRNAs including MIR17HG, H19, SNHG1, KCNQ1OT1, MALAT1, GAS5, SNHG20, OR2A1-AS1, and MAGI2-AS3 genes were involved in the development of COAD. Conclusions: Our data suggested several promising lncRNAs in the diagnosis and prognosis of patients with COAD. © 2020 The Author(s)
New Jersey in the American Revolution: a bibliography of historical fiction, from 1784
No full textby Oral S. Coad2nd ed. edited by Donald A. Sinclai
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Reflections on practical approaches to involving children and young people in the data analysis process
No full textThis article reflects on key methodological issues emerging from children and young people's involvement in data analysis processes. We outline a pragmatic framework illustrating different approaches to engaging children, using two case studies of children's experiences of participating in data analysis. The article highlights methods of engagement and important issues such as the balance of power between adults and children, training, support, ethical considerations, time and resources. We argue that involving children in data analysis processes can have several benefits, including enabling a greater understanding of children's perspectives and helping to prioritise children's agendas in policy and practice. (C) 2007 The Author(s). Journal compilation (C) 2007 National Children's Bureau
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