4,284 research outputs found
Letter, 1856 August 13, J. A. Lynch, Cincinnati, Ohio to Robert Tyler, Philadelphia, Pennsylvania
No full textWould like Tyler to investigate why Lynch never received a reply to his letter to the Secretary of the Navy concerning the voyage of the "new[?] frigate" to Ireland; Lynch feels that not only will it be a boon to Irisih Americans and American businessmen, it will Autograph Letter Signedo give hope to despairing Ireland. Autograph Letter Signe
Sonnet on an Air-Balloon
No full textPage from "The Universal Magazine" including a "Sonnet on an Air-Balloon" by Mrs. Piozzi [Hester Lynch].For more information about this item, visit https://archivesspace.mit.edu/repositories/2/digital_objects/70
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts
No full textLynch syndrome (LS) is characterised by the development of colorectal cancer, endometrial cancer and various other cancers, and is caused by a mutation in one of the mismatch repair genes: MLH1, MSH2, MSH6 or PMS2. In 2007, a group of European experts (the Mallorca group) published guidelines for the clinical management of LS. Since then substantial new information has become available necessitating an update of the guidelines. In 2011 and 2012 workshops were organised in Palma de Mallorca. A total of 35 specialists from 13 countries participated in the meetings. The first step was to formulate important clinical questions. Then a systematic literature search was performed using the Pubmed database and manual searches of relevant articles. During the workshops the outcome of the literature search was discussed in detail. The guidelines described in this paper may be helpful for the appropriate management of families with LS. Prospective controlled studies should be undertaken to improve further the care of these families
Thomas Lynch and Charles Bracelen Flood Interview (part 1)
No full textAn interview with Thomas Lynch and Charles Bracelen Flood in Richmond, Kentucky discussing their experiences during the Vietnam War on April 29, 1997. General Lynch was an officer in the 3rd Battalion of the 8th Army Infantry Division and Flood was a correspondent with the Associated Press and freelance author
Thomas Lynch and Charles Bracelen Flood Interview (part 2)
No full textAn interview with Thomas Lynch and Charles Bracelen Flood in Richmond, Kentucky discussing their experiences during the Vietnam War on April 29, 1997. General Lynch was an officer in the 3rd Battalion of the 8th Army Infantry Division and Flood was a correspondent with the Associated Press and freelance author
Licklider Correspondence
No full textCorrespondence between Kevin Lynch and J.C.R. Licklider regarding the proposed topic of study. The study discussed became the Perceptual Form of the City, a research project investigating the individual’s perception of the urban landscape
Frontmatter (Titlepage, Table of Contents, Author List, PC List, Reviewer List)
No full textFront matter including table of contents, author list, PC list, and reviewer list
The origins of bioethics: remembering when medicine went wrong/ John A. Lynch.
No full textIncludes bibliographical references and index."In this book, author John Lynch shows how three controversial experiments--the Tuskegee Syphilis Study, the Willowbrook Hepatitis Study, and the Cincinnati Total Body Irradiation Study--have been remembered and forgotten, and why their memorialization or their erasure matters today"--Bioethical memory and minimal remembrance -- Experiment or treatment? : histories of medical care, research, and regulation -- Lawsuits and legacies : competing memorializations of the Tuskegee Syphilis Study -- Minimal remembrance and the obligation to remember : official and vernacular memories of the Willowbrook State School -- Attempting to forget : the University of Cincinnati radiation studies.1 online resource
A Clinical Audit of a Lynch Syndrome referral protocol
No full textApproximately 14% of patients with colorectal cancer have tumours that exhibit a deficiency in mismatch repair (MMR) genes, of which 3% have Lynch syndrome where the mutations have germline origin. Lynch syndrome is associated with significant lifetime cancer risks, so early diagnosis is required to optimise outcomes (Vasen et al 2015). Previously family history assessment was used to identify individuals with Lynch syndrome, but a significant proportion were not identified due to familial heterogeneity.; therefore routine MMR immunohistochemistry testing of resected tumours (from patients with primary colorectal cancer aged 18 to 70 years old) has been practiced at a local NHS Trust since 2012. The primary aim of this testing was to inform treatment decision making, since the use of adjuvant chemotherapy is not beneficial in treating MMR deficient tumours. As a result of this testing, individuals with Lynch syndrome have been identified. Previous data suggests that only a small propo
The Blues of David Lynch
No full textInternational audienceThis article is an attempt to elaborate a typology of the color blue in the color films of David Lynch up to and including Mulholland Drive (2001). The color blue is considered alternately as light, matter or verbal language. The author studies the use, function, value and meaning of blue lighting, divided into static and flashing light, and of the blue objects in Blue Velvet (1986) and Mulholland Drive. The author shows how Lynch appropriates connotations Western culture, under the influence of Christian and romantic imagery, traditionally associates with the color blue in his cinematographic compositions. The author argues that this typology has bearing not only on the films' narratives and narrative structures, but also on the way the films represent the individual spectator's response to aesthetic effect as a form of nostalgia or blues
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