499 research outputs found
ILO/UNESCO (2016). The ILO/UNESCO Recommendation concerning the Status of Teachers (1966) and the UNESCO Recommendation concerning the Status of Higher Education (1997). Geneva: International Labour Office, Sectoral Policies Department. 78 pp.
No full textSanz Trigueros, F. J., & Guillén Díaz, C. (2017). ILO/UNESCO (2016). The ILO/UNESCO Recommendation concerning the Status of Teachers (1966) and the UNESCO Recommendation concerning the Status of Higher Education (1997). Geneva: International Labour Office, Sectoral Policies Department. 78 pp. Bordón. Revista De Pedagogía, 69(3), 204–206. Recuperado a partir de https://recyt.fecyt.es/index.php/BORDON/article/view/5519
Winkler model for predicting the dynamic response of caisson foundations
No full textThe paper presents a Winkler-based numerical model for the analysis of the dynamic response of caisson foundations. The model allows the evaluation of the impedance functions and of the foundation input motion (FIM), which can be used in the framework of the substructure approach to compute inertial soil-foundation superstructure interaction analyses. In addition, kinematic stress resultants due to seismic shear waves propagating into the soil can be estimated. The caisson is modelled as a Timoshenko beam and the soil-caisson interaction forces are derived from the analyses of the plane-strain vibration problem of an annular rigid ring embedded into the soil. The problem solution is obtained in the frequency domain exploiting the finite element approach and generic soil stratigraphies can be considered in the applications. The model, which is characterised by a very low computational effort, is validated by performing a parametric investigation, comparing results with those obtained from more rigorous BEM-FEM models of the soil-caissons systems. Finally, some applications to real caisson foundations of offshore wind turbines (OWTs) are shown to demonstrate the model accuracy in capturing the seismic response of the foundations obtained from more rigorous models
thrombocytopenia and thrombocytosis at time of hospitalization predict mortality in patients with community-acquired pneumonia
No full textBackground: Platelets are inflammatory cells with an important role in antimicrobial host defenses. We speculate that an abnormal platelet count may be a marker of severity in patients with community-acquired pneumonia (CAP). The objectives of this study were to evaluate if abnormal platelet count in hospitalized patients with CAP was associated with 30-day mortality and to compare platelet count and leukocyte count as predictors of 30-day mortality. Methods: We performed a retrospective cohort study of 500 consecutive patients hospitalized with CAP at the Veterans Hospital of Louisville, Kentucky, between June 2001 and March 2006 to investigate the association of platelet count and leukocyte count with 30-day mortality. Predictor variables were platelet count and leukocyte count. Abnormal platelet count was 400,000/L (thrombocytosis). The outcome variable was 30-day mortality. To control for potential confounding, a propensity score that incorporated 33 variables was used. Results: Platelet count was strongly associated ( P = .0009) with 30-day mortality, whereas no association was observed for leukocyte count ( P = .5114). High platelet counts resulted in a significantly increased risk of mortality. Conclusions: Thrombocytopenia and thrombocytosis are associated with mortality in patients hospitalized with CAP. When evaluating an initial CBC test in patients with CAP, an abnormal platelet count is a better predictor of outcome than an abnormal leukocyte count
The presence of pneumococcal bacteremia does not influence clinical outcomes in patients with community-acquired pneumonia : results from the Community-Acquired Pneumonia Organization (CAPO) International Cohort study
No full textBackground: It remains unknown whether pneumococcal bacteremia increases the risk of poor outcomes in hospitalized patients with community-acquired pneumonia (CAP). The objective of this study was to investigate whether the presence of pneumococcal bacteremia influences the clinical outcomes of hospitalized patients with CAP. Methods: We performed secondary analyses of the Community-Acquired Pneumonia Organization database of hospitalized patients with CAP and pneumococcal bacteremia, and patients with CAP and negative blood culture findings. To identify the effect of pneumococcal bacteremia on patient outcomes, we modeled all-cause mortality and CAP-related mortality using logistic regression analysis, and time to clinical stability and length of hospital stay using Cox proportional hazards models. Results: We studied 125 subjects with pneumococcal bacteremic CAP and 1,847 subjects with nonbacteremic CAP. The multivariable regression analysis revealed a lack of association of pneumococcal bacteremic CAP and time to clinical stability (hazard ratio, 0.87; 95% confidence interval [CI], 0.7 to 1.1; p = 0.25), length of hospital stay (hazard ratio, 1.14; 95% CI, 0.91 to 1.43; p = 0.25), all-cause mortality (odds ratio [OR], 0.68; 95% CI, 0.36 to 1.3; p = 0.25), and CAP-related mortality (OR, 0.86; 95% CI, 0.35 to 2.06; p = 0.73). Conclusions: Pneumococcal bacteremia does not increase the risk of poor outcomes in patients with CAP. Factors related to severity of disease are confounders of the association between pneumococcal bacteremia and poor outcomes. This study indicates that the presence of pneumococcal bacteremia by itself should not be a contraindication for deescalation of therapy in clinically stable hospitalized patients with CAP
Acute myocardial infarction in hospitalized patients with community-acquired pneumonia
No full textBackground. An epidemiological link between respiratory infection and acute myocardial infarction (AMI) has been suggested, and recent data indicate that there is an association between AMI and pneumococcal community-acquired pneumonia (CAP) in hospitalized patients. The objective of this study was to investigate the association of AMI with the severity of pneumonia at hospitalization and clinical failure during hospitalization among patients with CAP. Methods. An observational, retrospective study involving consecutive patients hospitalized with CAP was performed at the Veterans Hospital of Louisville, Kentucky. Patients admitted to the intensive care unit were defined as having severe CAP. Clinical failure was defined as the development of respiratory failure or shock. AMI was diagnosed on the basis of abnormal troponin levels and electrocardiogram findings. Propensity-adjusted models that controlled for clinical and nonclinical factors were used to investigate the association between AMI and pneumonia severity index and between AMI and clinical failure. Results. Data for a total of 500 patients were studied. At hospital admission, AMI was present in 13 (15%) of 86 patients with severe CAP. During hospitalization, AMI was present in 13 (20%) of 65 patients who experienced clinical failure. Following risk adjustment, significant associations were discovered between AMI and the pneumonia severity index score (modeled with a restricted cubic spline) (P = .05) and between AMI and clinical failure (P = .04). Conclusions. A combined diagnosis of CAP and AMI is common among hospitalized patients with severe CAP. In cases in which the clinical course of a hospitalized patient with CAP is complicated by clinical failure, AMI should be considered as a possible etiology
Parallel And Distributed Computational Multivariate Time Series Modeling In The State Space
No full textIn this paper a parallel and distributed computational procedure using a subspace method developed by Masanao Aoki for state space modeling of multivariate time series is proposed and implemented. The parallel solution of the Riccati equation due to the large computational effort it requires receives a special attention. For model evaluation, short time predictions, where a central role is played by a Kalman filtering approach are tested and some results are presented.214661471Akaike, H., Stochastic theory of minimal realization (1974) IEEE Transactions on Automatic Control, AC-19 (6), pp. 667-674. , DecemberAoki, M., (1990) State Space Modeling of Time Series, Second Ed., , Springer-VerlagBertsekas, D., Tsitsiklis, (1989) Parallel and Distributed Computations, , Prentice HallBlackford, L.S., Choi, J., Cleary, A., D'Azevedo, E., Demmel, J., Dhillon, I., Dongarra, J., Whaley, R.C., (1997) ScaLAPACK Users' Guide, , SIAM Publications, PhiladelphiaBottura, C.P., Barreto, G., Bordon, M.J., Costa Filho, J.T., State space modeling and high performance computing of multivariate time series (1997) Eigth SIAM Conference on Parallel Processing for Scientific ComputingBottura, C.P., Barreto, G., Bordon, M.J., Costa Filho, J.T., Séries Temporais No Espaço de Estado: Modelamento e Computação de Alto Desempenho (1997) XIV - Congresso Brasileiro de Engenharia Mecânica, Bauru, BrasilBottura, C.P., Tamariz, A.D.R., Barreto, G., Neto, F., Viana Da, J., Sequential and parallel algebraic riccati equations solutions via ESST on the schur method (1999) 38th IEEE Conference on Decision and ControlCaines, P.E., (1988) Linear Stochastic Systems, , Wiley(1991) Algorithms and Parallel VLSI Architectures, , Deprettere, E.F. and Van der Veen, Alle-Jan (ed.)Elsevier Science PubFaurre, P.L., (1973) Realisations Markoviennes de Processus Stationaires, (13). , IRIA - Rapport de RechercheMarchGolub, G.H., Van Loan, C.F., (1989) Matrix Computations, , The Johns Hopkins University PressGolub, G.H., Ortega, J.M., (1993) Scientific Computing: An Introduction with Parallel Computing, , Academic PressHamilton, J.D., (1994) Time Series Analysis, , Princeton U.PJainandunsing, K., Deprettrere, E.F., A new class of parallel algorithms for solving systems of linear equations (1989) SIAM J. Sci. Stat. Comput., 10 (5), pp. 880-912Kailath, T., (1980) Linear Systems, , Prentice-Hall, IncMoonen, M., (1990) Jacobi-Type Updating Algorithms for Signal Processing, Systems Identifications and Control, , Doctoral Dissertation, Department of Electrical Engineering, Katholieke Universiteit Leuven, BelgiumProakis, J.G., Rader, C.M., Fuyun, L., Nikias, C.L., (1992) Advanced Digital Signal Processing, , Macmillan Publishing CompanySnir, M., Otto, S., Huss-Lederman, S., Walker, D., Dongarra, J., (1996) MPI: The Complete Reference, , The MIT Press, Cambridge, MassachusettsStevens, W.R., (1990) UNIX Network Programming, , Prentice Hall Software SeriesTamariz, A.D.R., (1999) Uma Nova Proposta Para Solução Computacional da Equação Algébrica de Riccati em Formas Sequencial e Paralela, , Tese de Mestrado, UNICAMPVan Der Veen, A.-J., Deprettere, E.F., Swindlehurst, L.A., Subspace-based signal analysis using singular value decomposition (1993) Proceedings of the IEEE, 81 (9), pp. 1275-1308. , SeptemberVaughan, D.R., A nonrecursive algebraic solution for the discrete riccati equation (1970) IEEE Transactions on Automatic Control, AC-15 (5), pp. 597-599. , OctoberWiener, N., (1949) Extrapolation, Interpolation, and Smoothing of Stationary Time Series, with Engineering Applications, , New York, WileyWillems, J.C., From time series to linear system - Part I: Finite dimensional linear time invariant systems (1986) Automatica, 22 (5), pp. 561-580. , SeptemberWillems, J.C., From time series to linear system - Part II. Exact modeling (1986) Automatica, 22 (6), pp. 675-694. , NovemberWillems, J.C., From time series to linear system - Part III. Approximate modeling (1987) Automatica, 23 (1), pp. 87-115. , Januar
Football and nation-building in Gulf monarchies: Saudi Arabia, UAE and Qatar
No full textFootball is one of the remarkable mass phenomena of the globalisation era—a game followed by millions worldwide. No country remains alien to the enormous collective impact of football, where pure entertainment is mixed with political and power elements. In this sense, the populations of the Gulf monarchies have a long-standing connection with this sport, which leads them to combine their passion for national competitions and teams with the following of international tournaments, clubs, and stars.
Football expansion as a social phenomenon in the Gulf monarchies coincides with the construction and consolidation of nation-states throughout the 20th and early 21st centuries.
The most direct result is that this sport becomes an intrinsic part of the local identity and maintains a particular relationship with the established power.
The chapter analyses the socio-political dimension of football in Saudi Arabia, the United Arab Emirates (UAE) and Qatar. The research is structured in four sections. First, a brief historical overview of the development of football in the countries analysed. Second, the main objectives for which football can be used as a political tool. Third, how the case studies exhibit a close link between football and the construction of nation-states. Finally, the central dilemmas surrounding the future evolution of this sport within the Gulf monarchies.Depto. de Relaciones Internacionales e Historia GlobalFac. de Ciencias Políticas y SociologíaTRUEpu
Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia
No full textSummaryInflammation is a double-edged sword in the outcome of pneumonia. On the one hand, an effective and timely inflammatory response is required to eliminate the invading respiratory pathogen. On the other, a toxic and prolonged inflammatory response may result in lung injury and poor outcomes, even in those receiving advanced medical care. This review focuses on recent understanding of the dynamics of the cytokine response, neutrophil activity, and responsiveness to cytokines and neutrophil lifespan as major elements of lung inflammation resulting in favorable or poor outcomes in lung infection primarily due to pneumococcus and influenza virus. Although some progress has been made in our understanding of the molecular mechanisms of the pneumonia inflammation axis composed of cytokines modulating neutrophil activation and neutrophil apoptosis, important questions remain to be answered. The degree of neutrophil activation, generation of reactive oxygen species, and the release of granule antimicrobial peptides play a key role in microbial pathogen clearance; however, prolonged neutrophil activation may contribute to lung injury and poor outcomes in pneumonia. Molecular markers of the mechanisms regulating neutrophil survival and apoptosis may help in the identification of novel therapeutic targets to modulate inflammation by inducing timely neutrophil apoptosis. A major task is to identify the mechanisms of dysregulation in inflammation leading to toxic responses, thereby targeting a biomarker and enabling timely therapies to modulate inflammation
- …
