100,560 research outputs found

    Influence of experimental metabolic syndrome on bioimpedance spectroscopy indicators of rat body

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    Ivanenko T., Hrekova T., Abramova T., Shiryaeva A., Vasilenko G. Influence of experimental metabolic syndrome on bioimpedance spectroscopy indicators of rat body. Journal of Education, Health and Sport. 2021;11(08):470-479. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.08.053 https://apcz.umk.pl/JEHS/article/view/JEHS.2021.11.08.053 https://zenodo.org/record/5559742 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2021; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.08.2021. Revised: 16.08.2021. Accepted: 31.08.2021. UDC: 616-008.9-092:616-092-055.1/.2]-073:577.352.2]-092.9 INFLUENCE OF EXPERIMENTAL METABOLIC SYNDROME ON BIOIMPEDANCE SPECTROSCOPY INDICATORS OF RAT BODY T. Ivanenko, T. Hrekova, T. Abramova, A. Shiryaeva, G. Vasilenko Zaporizhzhia State Medical University, Zaporozhzhia, Ukraine [email protected] Abstract The objective of this experiment was to establish sex-related differences in the parameters of bioimpedance spectroscopy of the Wistar rat’s bodies in the experimental metabolic syndrome (endocrine-salt model). Sexual dependencies of bioimpedance measurements in intact animals have been determined for the first time: males have higher amount of total fluid, but lower one of total fat. The intra/extracellular fluid balance in males is characterized with ratio 2:1, while in females is the other one - 1:1. For the first time the formation of the metabolic syndrome has already been determined on the seventh day in females which lead to decreasing in the percentage of total fat and to changing of the intra / extracellular fluid balance to ‘male’ type - 2:1. The last one should be considered as a sign of intracellular hyperhydration. In males the examined parameters have been being within the control values throughout 21 days of experiment. Key words: bioimpedance spectroscopy; sex-related differences; metabolic disorders; corticosteroids; rats

    Cryptographic Transformations in a Decentralized Blockchain Environment

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    Distributed decentralized systems built using Blockchain technology are becoming increasingly popular and widespread. This is due to their reliability and security. But their transparency and openness, the lack of centralized administrative levers that can interfere and impose their decision, are the most important and attractive. Blockchain is able to provide completely anonymous, decentralized and free (uncontrolled) storage of any digital assets: from electronic money, such as cryptocurrencies, to secure property inventories and election registers. Therefore, further intensive implementation of this technology in various applications should be expected, as Blockchain implements a reliable and secure way to store distributed data in the decentralized environment. This is achieved through the use of various cryptographic transformations. This section analyzes the promising methods and mechanisms of cryptographic transformation that can be used in a decentralized Blockchain environment to provide various security services, including confidentiality, integrity, accessibility, indisputability, both users and elements/nodes of a decentralized system, etc. The section considers and investigates algorithms and protocols of homomorphic encryption, ring signatures, protocols with zero disclosure, principles of construction of anonymous secure networks, etc

    Letter, [Author unclear] to Paulina T. Merritt

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    Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.

    The research of modern stream ciphers

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    Synchronous stream ciphers produce long keystreams to be XORed with plaintext. The output keystreams should be indistinguishable from truly random sequences and should not leak any information about the secret key and the internal state of the cipher. In this study, we analyze of modern stream ciphers according to various criteria using methodology eSTREAM

    Modeling the socio-ecological-economic efficiency of resourse-saving development management of agri-food enterprises

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    Olena Lopushynska, Ievgen Buriak, Ihor Sabii, Liudmyla Pankova, Olena Ribeiro Ramos, Tetiana Ivanenko (2022). Modeling the socio-ecological-economic efficiency of resource-saving development management of agri-food enterprises. Journal of Hygienic Engineering and Design, Vol. 39, pp. 242-251

    An EcoRI-RsrI chimeric restriction endonuclease retains parental sequence specificity

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    To test their structural and functional similarity, hybrids were constructed between EcoRI and RsrI, two restriction endonucleases recognizing the same DNA sequence and sharing 50% amino acid sequence identity. One of the chimeric proteins (EERE), in which the EcoRI segment His147-Ala206 was replaced with the corresponding RsrI segment, showed EcoRI/RsrI-specific endonuclease activity. EERE purified from inclusion bodies was found to have ∼ 100-fold weaker activity but higher specific DNA binding affinity, than EcoRI. Increased binding is consistent with results of molecular dynamics simulations, which indicate that the number of hydrogen bonds formed with the recognition sequence increased in the chimera as compared to EcoRI. The success of obtaining an EcoRI-RsrI hybrid endonuclease, which differs from EcoRI by 22 RsrI-specific amino acid substitutions and still preserves canonical cleavage specificity, is a sign of structural and functional similarity shared by the parental enzymes. This conclusion is also supported by computational studies, which indicate that construction of the EERE chimera did not induce substantial changes in the structure of EcoRI. Surprisingly, the chimeric endonuclease was more toxic to cells not protected by EcoRI methyltransferase, than the parental EcoRI mutant. Molecular modelling revealed structural alterations, which are likely to impede coupling between substrate recognition and cleavage and suggest a possible explanation for the toxic phenotype. © 2007 Elsevier B.V. All rights reserved

    Drawing ellipses in water: evidence for dynamic constraints in the relation between velocity and path curvature

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    Several types of continuous human movements comply with the so-called Two-Thirds Power Law (2/3-PL) stating that velocity (V) is a power function of the radius of curvature (R) of the endpoint trajectory. The origin of the 2/3-PL has been the object of much debate. An experiment investigated further this issue by comparing two-dimensional drawing movements performed in air and water. In both conditions, participants traced continuously quasi-elliptic trajectories (period T = 1.5 s). Other experimental factors were the movement plane (horizontal/vertical), and whether the movement was performed free-hand, or by following the edge of a template. In all cases a power function provided a good approximation to the V-R relation. The main result was that the exponent of the power function in water was significantly smaller than in air. This appears incompatible with the idea that the power relationship depends only on kinematic constraints and suggests a significant contribution of dynamic factors. We argue that a satisfactory explanation of the observed behavior must take into account the interplay between the properties of the central motor commands and the visco-elastic nature of the mechanical plant that implements the commands

    Modeling the socio-ecological-economic efficiency of resourse-saving development management of agri-food enterprises

    No full text
    Olena Lopushynska, Ievgen Buriak, Ihor Sabii, Liudmyla Pankova, Olena Ribeiro Ramos, Tetiana Ivanenko (2022). Modeling the socio-ecological-economic efficiency of resource-saving development management of agri-food enterprises. Journal of Hygienic Engineering and Design, Vol. 39, pp. 242-251

    Handwritten biographical information on Paulina T. McClung Merritt

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    A handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
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