103 research outputs found
Java For Dummies
No full textBarry Burd, PhD, is a Computer Science professor at Drew University where he has been named to Drew's "List of Teachers Ranked as Excellent by Students" five times. Barry is the author of numerous For Dummies books and writes frequently for several online publications, including JavaBoutique.co
Burd publishes report on prenatal alcohol exposure
No full textGRAND FORKS, N.D.—Currently, about 50 percent of infants in the United States and in North Dakota have some alcohol exposure in early pregnancy. Most of these infants’ mothers then quit drinking. However, about 6 to 10 percent of pregnant women drink throughout their pregnancy.
“Many people thinking about this issue would recognize the link between maternal drug use and developmental problems, which is a major public health issue in the United States and across the world,” said Larry Burd, PhD, a professor in the Department of Pediatrics at the University of North Dakota School of Medicine and Health Sciences, and director of the Fetal Alcohol Syndrome Center at the UND SMHS. The center provides prevention, diagnostic, and treatment services for people of all ages who have concerns related to prenatal alcohol exposure.
“However, the much larger problem of prenatal alcohol exposure is a far more serious and much larger public health issue across the world and in North Dakota that is often overlooked,” Burd said. “This level of prenatal exposure is linked to increasing rates of complications during pregnancy and in the newborn.”
The 2015 North Dakota Legislative Assembly created the North Dakota Task Force on Substance Exposed Newborns to study the growing problem and to produce a report for the 65th Legislative Assembly, convening in 2017. Burd was the author of the report submitted to the task force, A Report to the North Dakota Task Force on Substance Exposed Newborns.
“In some cases these children will have a fetal alcohol spectrum disorder,” Burd said. “These disorders typically are lifelong disorders and extremely costly. The tragedy here is that these are preventable conditions
Java for dummies
No full textThe top-selling beginning Java book is now fully updated! As an unstoppably platform-independent, object-oriented programming language, Java is used for developing web and mobile applications. In this up-to-date bestselling book, veteran author Barry Burd shows you how to create basic Java objects and clearly explains when you should simply reuse existing code. Explores how the new version of Java offers more robust functionality and new features such as closures to keep Java competitive with more syntax-friendly languages like Python and Ruby Covers object-oriented programming basics with J
Die Legitimität der §§ 284, 285 StGB
No full textSeit der Einführung der §§ 284, 285 in das deutsche StGB ist die Frage, ob der Gesetzgeber die in den§§ 284, 285 StGB beschriebenen Verhaltensweisen strafrechtlich verfolgen darf, stark umstritten. Besonders stark hinterfragt wird, welches Rechtsgut durch §§ 284, 285 StGB geschützt werden soll. Die Frage erscheint insbesondere im Hinblick auf die verwaltungsakzessorische Ausgestaltung dieser Strafnormen und die Tatsache, dass der Staat stark von den Einnahmen aus dem Glücksspielmarkt profitiert, interessant. Die Arbeit stellt zunächst die zu dem von §§ 284, 285 StGB geschützten Rechtsgut üblicherweise vertretenen Ansichten dar und arbeitet sodann Kriterien heraus, die für die Beurteilung der Legitimität einer Strafnorm von Bedeutung sind, wobei unter anderem auf die jeweilige Deliktsstruktur Wert gelegt wird. Die daraus gewonnenen Erkenntnisse werden anschließend der Beurteilung der Legitimität der §§ 284, 285 StGB zugrunde gelegt, die zum Ergebnis kommt, dass diese Strafnormen nicht im vollen Umfang aufrechterhalten werden sollten.»Legitimacy of §§ 284, 285 StGB«: Since the introduction of §§ 284, 285 into the German Criminal Code, the question whether the legislator is allowed to prosecute the conduct described in §§ 284, 285 StGB has been highly controversial. After outlining the basic requirements for the legitimacy of a criminal norm, the author devotes herself to examining the legitimacy of §§ 284, 285 StGB and comes to the conclusion that the aforementioned criminal norms should not be upheld in their entirety
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Heidi
No full textEarly edition of Heidi by Johanna Spyri and edited by Adeline B. Zachert and illustrated by Clara M. Burd. The cover is covered in black fabric with a color illustration in the center. The illustration is of Heidi with her grandfather outside, feeding three goats from their hands. The illustration is surrounded by symmetrical floral motifs and the title and illustrator's name in gold. On the spine is the title, and author's and publisher's names. The floral motifs also continue on the spine. Also on the spine is a strip with red and yellow stripes with "GCW" in cursive on it to mark the owner, Gustine Courson Weaver. The cover page has more floral motifs in blue and red. At the tip is a box with the title and in the center is another box with the names of the author, editor, illustrator, and publishing company in the same blue as the motifs. On the opposite page is a full color illustration of Heidi and other boy holding walking sticks, standing in a grassy clearing of a forest with some goats. In the background are tall evergreen trees and tree stumps. The illustration is captioned with "The Children Started Joyfully for the Mountain." On page 29 is a graphite drawing of Heidi sitting on a stool, drinking from a bowl. It's captioned with "Heidi Lifted the Bowl with Both Hands". Page 99 has an illustration of Heidi and a girl named Clara cuddling with cats. Clara is sitting in a chair with her back supported by several pillows and her lap laden with blankets. In one arm is a kitten. Standing next to her is Heidi with the other kitten. Opposite of Clara is a table with books and a pitcher. Next to the table is a window with the shutters and curtains opened to let in light. The illustration is captioned with "Clara with the Kittens On Her Lap". On page 137 is another pencil drawing of Heidi in a long white nightgown. Its captioned "There In Her White Nightgown Stood Heidi". Page 155 is a full color illustration of Heidi standing outside in a clearing. In one hand she is holding a basket while her other hand is hidden by her head. On either side of the path she is standing on are rocks, grass, and flowers. Further down the path are two goats grazing next to a pile of large rocks. Next to the rocks opposite of the goats is a wooden fence and some tall evergreen trees. At the end of the path is Heidi's grandfather smoking in front of his cabin. In the background are mountains jutting against the sky. The illustration is captioned "There was Grandfather Sitting as in the Old Days
Xianggang shao shang zhu yuan huan zhe de liu xing bing xue yan jiu
No full textPh.D.Introduction. Epidemiology is the science of studying health risks in populations. Many previous studies on burn injury have focussed on individual patients. The objective of this study is to determine the distribution of burn injury in eighteen defined geographical districts with the aim of identifying possible population-based determinants of risk.Methodology. Patient data comes from the first ten years in which electronic patient records were available, 2002 – 2011. A key linking field identifies the patient’s district of residence. These districts are described in Census reports. Using descriptive statistics, the eighteen districts and the risk of burn injury are characterised and compared. Using analytical statistics, the relationship between changes in burn incidence rates and changes in key characteristics of each district are examined.Results. Heterogenicity is demonstrated in district characterization and in burn incidence and occurs both within each year of study and throughout the study period. Analysis of potential determinants of burn injury is complex due to the multiple variables and the relatively few data points in the ten-year study period. The district with the highest incidence of burns, including the most vulnerable group, 0-2-year-olds, ranked lowest in monthly household income, % of people of working age in the labour force and average household size and highest in the % of elderly in the population. This association remained constant, however the risk (incidence of burn injury) is falling whilst the proportion of that district population with higher education is increasing. Conversely, the district with the lowest incidence of burn injury had the highest average monthly income and the highest proportion of the population with higher education throughout the study period.Conclusions. It is evident that risks do change and that improving levels of education and economic status within populations are associated with reduced risk of burn injury. The mechanism of this association is unclear, and it is proposed that an active process of surveillance, with more attention to qualitative data, should be considered particularly regarding reducing serious domestic injuries.前言：流行病學是研究人群健康風險的科學。過往許多關於燒傷的研究集中於個別患者，而本論文旨在通過研究燒傷患者在香港十八個行政區的分佈，以確定可能基於人口分佈的風險因素。方法：患者數據來自2002至2011十年期間的電子病歷，以患者的居住地區作爲關鍵詞分類，而居住地區以人口普查報告為依據。 本論文使用描述性統計學方法，對十八個行政區及其燒傷風險進行了表徵描述和比較。 使用分析性統計學方法，分析了燒傷發生率變化和各區關鍵特徵變化之間的關係。結果：每年以及在整個研究期間，各行政區的表徵和燒傷發生率均有差異。 由於在十年研究期內存在多個變量且數據點相對較少，分析潛在影響燒傷發生的決定因素非常複雜。 燒傷發生率最高的地區，包括0-2歲最脆弱的群體， 其家庭月收入、勞動人口百分比、平均居住面積是最低的，而老年人口百分比最高。即使隨著該區受高等教育的人口比例增加，燒傷發生風險會下降，但這種關聯性維持不變。相反，燒傷發生率最低的地區，其家庭平均月收入以及受高等教育的人口比例最高。結論：顯然，燒傷發生的風險確實會改變。隨著人口中受教育程度和經濟收入的提高，燒傷發生的風險降低。 但這種關聯性的機制尚不清楚，因此建議進行積極的監察、更多關注質量性數據，以減少嚴重的家居受傷。Burd, David Andrew Ross.Thesis Ph.D. Chinese University of Hong Kong 2020.Includes bibliographical references (leaves 277-289).Abstracts also in Chinese.Title from PDF title page (viewed on November 18, 2021).Burd, David Andrew Ross
Reply to Rosenblum et al. and Carriquiry and Ommen: Understanding probative value, triers-of-fact, and usefulness of validity study results
No full textWe thank Rosenblum et al. (1) and Carriquiry and Ommen (2) for their interest in our article (3) regarding the validity of cartridge-case comparisons. They make three assertions: that we misrepresent the technique's probative value, that setting trier-of-fact pretest odds = 1 is improper, and that our results may not speak to the validity of the forensic technique. We appreciate the opportunity to clarify these misunderstandings, which we address in turn.
Rosenblum et al.'s belief that we misrepresent the technique’s probative value stems from their viewing trier-of-fact posttest beliefs as the measure of probative value (or, in their words, “strength of forensic evidence”). In fact, the likelihood ratio is the true measure of probative value. Guyll et al. correctly highlight the likelihood ratio as the empirical probative value measure that determines how much change is justified in trier-of-fact beliefs from any particular pretest value to a consequent posttest value. Likewise, the actual transcript (4) of the relevant testimony cited by Rosenblum et al. reveals an accurate portrayal of the technique’s probative value as quantified by the likelihood ratio by showing how much change it would justify in the trier-of-fact beliefs from an initial pretest value to a consequent posttest value. Nowhere do Guyll et al. or the testimony improperly represent posttest beliefs as the measure of probative value.This reply is published as M. Guyll, S. Madon, Y. Yang, K.A. Burd, G. Wells, Reply to Rosenblum et al. and Carriquiry and Ommen: Understanding probative value, triers-of-fact, and usefulness of validity study results, Proc. Natl. Acad. Sci. U.S.A.
121 (45) e2316886121. https://doi.org/10.1073/pnas.2316886121 (2024). Copyright © 2024 the Author(s). Published by PNAS. This article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND)
Author attitudes to professional medical writing support
No full textTo understand academic/clinician authors’ perceptions regarding the value of professional medical writers. An online survey of academic/clinician authors was conducted to understand the value of professional medical writer support in the development of publications (abstracts, posters and manuscripts). Responses were collected anonymously. The survey used a negative-to-positive, 6 point scale to evaluate respondents’ opinions and experiences of working with professional medical writers, and multiple choice to indicate in which areas professional medical writers added value. Responses from 76/260 authors were received (Europe, n = 57; 75.0%; North America, n = 16; 21.1%; Asia-Pacific region, n = 3; 3.9%). The majority of respondents were either clinicians (n = 45; 59.2%) or academic researchers (n = 25; 32.9%). A total of 82.9% (63/76) of respondents felt that it was acceptable to receive professional medical writer assistance with their publications, and 84.0% (63/75) valued the assistance provided. The services most valued (>50 responses) were editing and journal styling, conformity with reporting guidelines (e.g. CONSORT) and manuscript submissions. Fewer respondents (25–49 responses) valued management of timelines and co-author reviews, scientific/technical writing assistance and expert guidance on authorship requirements/good publication practice. The least valued service was the scientific expertise of the professional medical writer (3 responses). Respondents to this survey were generally accepting of medical writing assistance and valued many aspects of the role, in particular editorial support. The survey was small, however, and potentially biased towards authors with experience of working with medical communication agencies. Although many medical writers come from a scientific background and have relevant expertise, this was not perceived as a value. It would be beneficial to educate authors and journal editors regarding medical writers’ scientific expertise and role.</p
Perivascular cell contribution to skeletal muscle repair following physiological injury
No full textPURPOSE: We have previously demonstrated that muscle-derived mesenchymal stem cells (MSCs; Sca-1+CD45-) accelerate Pax7+ satellite cell expansion and fiber repair during the initial stages of eccentric exercise training in mice. MSCs are a heterogeneous population of perivascular stromal cells, including but not limited to, pericytes, fibroadipogenic progenitor cells, and smooth muscle cells. Therefore, the purpose of this study was to examine the specific contribution of muscle-derived pericytes (CD146+CD45-CD31- or CD146+Lin-) to skeletal muscle repair following physiological injury. METHODS: Adult male wild type mice received bilateral intramuscular injection of pericytes 24 hr after a single bout of resistance exercise initiated by electrical stimulation of the sciatic nerve (n=5-6/group). Mice were sacrificed 4 days post-stimulation and the tibialis anterior muscles were analyzed for markers of damage (IgG+ myofibers, collagen), inflammation (CD11+ cells), and repair (fiber CSA, CLN+ fibers, myonuclei content). To determine the impact of the pericyte secretome on myoblast expansion and myotube development, CD146+Lin- pericytes were isolated from adult male wild type mouse skeletal muscle via enzymatic digestion and FACS. Following 12 days of recovery in culture, isolated pericytes were subjected to strain (10%, 1 Hz) for 1 hr using a Flexercell Strain unit. Conditioned media (CM) was collected from strained (CM-S) or unstrained (CM-NS) pericytes 24 hr later and applied to C2C12 myoblasts for up to 72 hr. RESULTS: Pericyte transplantation following electrical stimulation inhibited inflammation based on CD11b+ quantity and recovered the capillary-to-fiber ratio (P<0.05). The application of CM-S simultaneously reduced C2C12 quantity and increased myotube formation compared to CM-NS (P<0.05). CONCLUSION: The results from this study suggest that CD146+Lin- pericytes contribute to skeletal muscle repair after physiological injury.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2022-05-01The student, Gabriela Garcia, accepted the attached license on 2020-05-01 at 10:24.The student, Gabriela Garcia, submitted this Thesis for approval on 2020-05-01 at 10:31.This Thesis was approved for publication on 2020-05-05 at 15:06.DSpace SAF Submission Ingestion Package generated from Vireo submission #15141 on 2020-08-25 at 17:42:26Made available in DSpace on 2020-08-27T00:50:15Z (GMT). No. of bitstreams: 2
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