408 research outputs found
Postoperative maintenance therapy for inflammatory bowel disease
. Curr Opin Gastroenterol. 2006 Jul;22(4):377-81.
Postoperative maintenance therapy for inflammatory bowel disease.
Cottone M, Orlando A, Modesto I.
Department of General Medicine, Pneumology and Nutrition Clinic, Palermo
University, Palermo, Italy.
PURPOSE OF REVIEW: This review will highlight the knowledge gained from studies
published in the year 2005 on maintenance treatment after surgery for
inflammatory bowel diseases.
RECENT FINDINGS: In Crohn's disease the role of smoking in increasing the risk of
relapse and recurrence after surgery is confirmed. Ornidazole seems effective in
reducing endoscopic recurrence and clinical relapse after surgery. Probiotics do
not appear to be effective in preventing endoscopic recurrence and clinical
relapse: a controlled placebo trial showed that Lactobacillus johnsonii is not
effective in preventing endoscopic recurrence. A retrospective study suggested
that enteral nutrition after surgery may reduce the clinical relapse.
Pathophysiological studies underlined the value of probiotics in pouchitis.
SUMMARY: In Crohn's disease postoperative maintenance treatment is disappointing.
Giving up smoking is still the only effective measure. Mesalamine remains the
drug that has been widely studied with large trials and meta-analysis.
Encouraging results come from small trials on antibiotics. Azathioprine and
6-mercaptopurine must be evaluated in better designed controlled trials. There is
no evidence in favour of probiotics as an effective therapy to prevent
recurrence. Enteral nutrition after surgery is a candidate new therapy, but
further controlled trials are needed. Pathophysiological studies confirm the
beneficial role of probiotics in pouchitis
O sujeito e o campo: reflexões sobre o direito e a crise da subjetividade moderna
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Jurídicas. Programa de Pós-Graduação em Direito.Esta dissertação propõe-se a traçar um caminho que proporcione visualizar e discutir os dilemas propostos à subjetividade e ao direito dentro do cenário político da modernidade
Politics: (re)composition of the object
Política: (re)composição do objeto. O autor pretende demonstrar que a "força" é um dado superestimado da política, por petição de princípio dos modelos teóricos que instrumentalizam a Sociologia, a Teoria Política, e a normação da espécie Direito (Normação latina e anglo-saxã), e em razão de tais disciplinas compartilharem do cadinho mitologico ácade, reproduzido por helenos e hebreus, e induzido na diluição religiosa dos respectivos fundamentos cognitivos. Sobre o objeto política (mando e força justificáveis), o autor superporá o método complexo físico-semiótico (1) da Semioselogia, includente da fenomenologia Física (Heisenberg, Bohr, Lao Tzy), da Signologia (Peirce), do Instrumento Operacional da Pragmática (Modesto), e (2) da Hominilogia (Modesto), para descrever comparativamente os padrões de civilidade na família hominidaæ (bonobos, humanos, chimpanzés), e quais deles dominam na ação política por mando (Normações) e por força dos humanos no mercado mundial, respectivamente, política bonobo e política chimpanzé.Politics: (re)composition of the object. The author intends to demonstrate that the "force" is a superestimated datum of the politics, for postulation of the beginning of the theoretical models that instrumentalize the Sociology, the Political Theory, and the normaction of the species Law (latin and anglo-saxon Normaction), and in reason of such disciplines in partaking as cognitive foundation the mythological acadian crucible, reproduced by greeks and hebrews, and induced in the religious dilution of the respective cognitive foundations. On the politics object (justifiable exact and force), the author will superpose the semiotics-physics complex method (1) of the Semioselogy, including of the Physics phenomenology (Heisenberg, Bohr, Lao Tzy), of the Signology (Peirce), of the Progmatic Operational Instrument (Modesto), and (2) of the Hominilogy (Modesto), to comparatively describe the civility patterns in the hominidae family (bonobos, humans, chimpanzees), and which dominate in the political action by exact (Normactions) and by force of the humans in the world market, respectively, bonobo politics and chimpanzee politics
sj-docx-1-tag-10.1177_17562848221136331 – Supplemental material for Modified Mayo score versus Mayo score for evaluation of treatment efficacy in patients with ulcerative colitis: data from the tofacitinib OCTAVE program
Supplemental material, sj-docx-1-tag-10.1177_17562848221136331 for Modified Mayo score versus Mayo score for evaluation of treatment efficacy in patients with ulcerative colitis: data from the tofacitinib OCTAVE program by William J. Sandborn, Bruce E. Sands, Séverine Vermeire, Yvette Leung, Xiang Guo, Irene Modesto, Chinyu Su, Wenjin Wang and Julian Panés in Therapeutic Advances in Gastroenterology</p
sj-docx-2-tag-10.1177_17562848211054710 – Supplemental material for Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies
Supplemental material, sj-docx-2-tag-10.1177_17562848211054710 for Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies by Charlie W. Lees, J. Jasper Deuring, Michael Chiorean, Marco Daperno, Gianluca Bonfanti, Rebecca Germino, Pritha Bhadra Brown, Irene Modesto and Roger A. Edwards in Therapeutic Advances in Gastroenterology</p
sj-docx-1-tag-10.1177_17562848211054710 – Supplemental material for Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies
Supplemental material, sj-docx-1-tag-10.1177_17562848211054710 for Prediction of early clinical response in patients receiving tofacitinib in the OCTAVE Induction 1 and 2 studies by Charlie W. Lees, J. Jasper Deuring, Michael Chiorean, Marco Daperno, Gianluca Bonfanti, Rebecca Germino, Pritha Bhadra Brown, Irene Modesto and Roger A. Edwards in Therapeutic Advances in Gastroenterology</p
Leucocytapheresis in patients with moderate severe steroid dependant Ulcerative Colitis:clinical response without endoscopic response
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