1,387 research outputs found
Reverse control of biological networks to restore phenotype landscapes
No full textBiological systems consist of genetic elements and their regulatory interactions, forming networks that maintain life. However, accumulated alterations such as DNA damage can distort biological behavior, leading to undesirable responses to stimulus. This raises the question of whether we can restore their nominal stimulus-response relationships. Current control approaches tend to enforce a single desired response rather than restore the proper capacity for variable responses to different stimulus. Here, we present an algebraic reverse control (ARC) framework for reversion of altered biological networks. ARC leverages matrix operations to quantify the phenotype landscape of the altered network and identifies reverse control targets for recovering the phenotype landscape of a nominal network. ARC is scalable to large Boolean networks and identifies effective control targets to restore biological behavior.
Sonochemical synthesis of Pt-deposited SiO2 nanocomposite and its catalytic application for polymer electrolyte membrane fuel cell under low-humidity conditions
No full textThe direct deposition of platinum (Pt) nanoparticles on the surface of SiO2 without surface modification was attempted by irradiating ultrasound. This method enabled the formation of Pt nanoparticles with a narrow-sized distribution. The nanocomposites were blended with conducting carbon and applied as an anode catalyst for polymer electrolyte membrane fuel cell. With various anode relative humidity, the membrane fabricated with the catalyst exhibited tolerance toward water-deficient condition showing sustainable performance, while the membrane with commercial catalyst degraded sharply. This was attributed to the SiO2's water-uptake ability, which retained the hydration level in the membrane under low humidity. (C) 2012 Elsevier B.V. All rights reserved
Hyun Jaemyeong’s Opera Chunhyang-Jeon: Ancient Traditions and Western Perspectives
No full textabstract: ABSTRACT
Korea’s first opera Chunhyang Jeon was composed by Jaemyeong Hyun in 1948. Until that time, most Korean vocal music was sung by a few native traditional artists. Inspired by their work, composer Hyun combined elements from the ancient Pansori (epic poetic forms presented by a solo singer with drum) and Western music techniques to create his opera. Hyun also used the more vernacular Hangeul (Korean alphabet) for his libretto rather than the Chinese usually heard in Korean theatrical presentations. It might be noted that in that same year (1948), the first Western opera: Verdi’s La Traviata was performed in Seoul.
This study concerns the bringing together of Korean traditional idioms (in Pansori) and Western musical ideas (harmony, orchestration, etc.) to create what is now known as Chunhyang-jeon Opera. In this regard, the author will present a brief split-analysis of the older style and the more modern musical attributes of the combined style of traditional Korean music and European style opera. It is hoped that this study might provide the basis for a future opera course and guide for both disciplines.
This study will also show that the Pansori and its subsequent operatic treatment has historical, social and artistic elements. Some similarities and differences of both forms were noted here with regard to cultural sensitivities.
While Chunhyang-ga (older form) and Chunhyang-jeon (Hyun’s modern adaptation) have some musical similarities, the latter was not composed based on the former. Chunhyang-ga consists mainly of compound meter (6/8, 9/8, 12/8, 24/8), which is at the heart of Korean traditional music, while Chunhyang-jeon uses simple meter (2/4, 3/4, 4/4).
Identical words are not often used in the two works, but their libretti are of much significance. Chunhyang-ga had been traditionally handed down with Chinese characters, whereas Chunhyang-jeon constituted its libretto with more modern Korean words which were easily understood by the audience.
Pansori have been sung with traditional singing techniques, which demonstrate the flow of the melodic line found in the images of the words (as interpreted and improvised by the solo performer), while in opera, vocal music is primarily from a set of melodic and harmonic techniques.Dissertation/ThesisDoctoral Dissertation Music 201
[Review of] Peter Hyun. MAN SEI! The Making of a Korean American
No full textThis book offers a history of Korea from the tum of the century through the end of World War II. But it is more than that: It is an autobiographical account of Peter Hyun, who with his family, witnessed and participated in the making of modern Korean history. Hyun, born in 1907, was one of eight children who lived and went to school under Japanese rule. In 1919 he witnessed a massive demonstration in which thousands of Koreans shouted MAN SEI! -- Long Live Korea -- and watched as Japanese police and military killed countless demonstrators, hence the title of this book. The author\u27s father, the Rev. Soon Hyun, spent his career serving the Methodist church and leading the movement for Korean independence
High-Speed and Low-Temperature Atmospheric Photo-Annealing of Large-Area Solution-Processed IGZO Thin-Film Transistors by Using Programmable Pulsed Operation of Xenon Flash Lamp
No full textAn efficient photo-annealing approach for high-performance solution-processed metal-oxide thin film transistors (TFTs) was demonstrated by using programmable pulse operation of xenon flash lamp. The flash lamp annealing (FLA) process could offer not only low-temperature (≈100° C) processing but also ultra-fast annealing speed of the order of seconds under air ambient conditions. Solution-processed amorphous indium-gallium-zinc-oxide (α-IGZO) TFTs implemented by the FLA process typically exhibited much improved electrical performance such as saturation mobility of >10.8 cm2V−11s−1, ION/IOPP of >108, and subthreshold slope of as steep as 0.24 V/dec. X-ray photoelectron spectroscopy analysis of a-IGZO films indicates that the FLA can provide sufficient activation energy for rapid formation of solid a-IGZO bonds within 30 s. The high-quality metal-oxide films achieved by an atmospheric and low temperature FLA method may represent a significant advance for scalable fabrication of flexible and printed metal-oxide electronics. © 2019, The Korean Physical Society.1
Yun, Gi-Hyun
No full text학위논문(석사)--아주대학교 일반대학원 :전자공학과,2008. 8영상 이미지를 이용한 대부분의 광고 매체가 실시간 데이터 전송을 통한 이미지의 전달 및 멀티기능을 내포하면서 TV기능을 내장한 솔루션이 요구된다.
따라서 본 논문에서는 네트워크를 통한 영상의 전송 및 다양한 형태의 이미지 및 파일들을 전송하고 이미지의 다양한 포맷에 따른 구현과정 및 저전력의 효율적인 시스템을 기반으로 하는 디지털 정보 표시장치(DID) 솔루션의 설계 기법 즉, 인터럽트 서비스 루틴을 기반으로 각종 인터페이스를 인식하고 영상 데이터를 받아서 mpeg4 모듈에서 영상과 오디오에 대한 스트림을 받아서 비디오 스트림을 만들어 디스플레이 장치에 두 개의 메모리 채널을 만들어 영상의 확대 및 축소등의 다양한 기능을 논하였다.
본 논문에서는 이더넷을 이용한 솔루션은 스케일러 보드의 외장형 타입으로서 기존 멀티미디어의 다양한 기능을 내포하면서도 미들웨어기반의 이더넷을 통한 실시간 데이터 전송이 가능하고, 외장형으로 붙여지는 스케일러의 성능에 따라 다양한 포맷의 영상 데이터를 표시하므로 해상도에 따른 제약 없이 영상 및 다양한 매개체의 이미지 및 파일들을 처리할 수 있다.
이러한 시스템을 통하여 사용자에게 다양하고도 실시간적인 멀티미디어 기능을 제공하여 변화하는 사용자의 다양한 욕구를 만족시키고자 고해상도의 화질을 기본으로 하는 멀티미디어 기능을 구현하여, 기존 시스템과는 화질면에서 320*240에서 720*480의 동영상을 재생하고 디스플레이 장치의 해상도에 제약없이 화면 가득 영상을 재생하는 등 기능면에서 차별화를 추구하였다.＜제목차례＞ = Ⅰ
＜그림차례＞ = Ⅲ
＜표차례＞ = Ⅴ
제1장 서론 = 1
제2장 디지털 정보 표시장치(DID)솔루션 = 4
제1절 전자앨범 시스템 기술적 구성 이론 = 4
제2절 OS기반의 시스템 구성 이론 = 6
제3장 디지털 정보 표시장치 설계 = 7
제1절 접속 장치 설계 = 7
제2절 정지 영상 모듈 설계 = 13
제3절 동영상 모듈 설계 = 18
제4절 미들웨어 설계 = 20
제4장 어플리케이션 구현 = 25
제1절 프리 뷰어 모드 및 스냅샷 모드 = 26
제2절 비디오 처리 모드 = 32
제3절 미디어 재생 모드 = 36
제5장 측정 실험 = 38
제1절 이미지 디스플레이 모듈 = 38
제2절 디스플레이 윈도우 규정 및 적용 = 41
제6장 결론 = 45
제7장 참고문헌 = 48
제8장 ABSTRACT = 50MasterIn this dissertation, the author improves the problems of existing Digital Information Display(DID) solution and Real-Time Embedded system executes via FTP Protocol within TCP/IP and implementes a low-cost embedded system.
Existing Digital Information Display(DID) solution has trouble problems with low-quality image, low-speed system, no-real-time system. To settle these problems, the author decides to use Middleware(TCP/IP) soulutions within MP522 chip.
The MP522 Chip is a highly integrated and flexible multimedia processor targeting low power multimedia applications. It is designed to provide high-quality digital still image capture, video recorder, media player and graphic display control. so It incorporates a 32-bit RISC main processor, a high-quality image signal processing engine, MPEG-4/H.263 video codec, LCD/LCM display controller with graphic overlay functions, AMR/MP3/AAC and WAV/MIDI audio codec, SD/MMC/MS memory card, and USB 2.0 High-speed device controllers. and It is applied TCP/IP Mode with Ethernet. Ethernet can implement real-time embedded system and varaible contents be easily upgraded.
The Sensor Interface Unit(SIU) supports imager resolutions up to 5M-pixels, with horizontal dimension up to 2560 pixels. and It supports CCD and CMOS sensors Up to 10-bit resolution for Bayer RGB or 4:2:2 YCbCr/YUV. CCIR601 input.
The Image Processing Unit(IPU) is dynamic dead pixel correction. it is implemented with software application. it supports Configurable image sharpening and filtering processing for special effect. The special effect is required new technique with customer's requires. It includes Image's Rotate, Image's Flip function. The Image Processing Unit(IPU) needs to control Image's processing and display states. and It needs to display several moving picture's format.
The Image Display Unit(IDU) supports variety of LCD/LCM interfaces, including 18-bit parallel and 8-bit serial digital RGB, i80 or m68 MPU, and CCIR-656/CCIR-601/CCIR-709 interface. It needs to control Programmable color space conversion and Graphic overlay with alpha blending, background color & transparent color key. The Graphic overlay is required to implement the special effect within Image and moving picture. It applies the special function such as to support color dithering with 4x4 window size and to control RGB video interface with programmable video timing.
The MPEG4 Codec(MP4) supports H.263 and MPEG-4 Simple Profile up to Level 5. It applies Proprietary motion estimation algorithm in +31/-32 half-pixel resolution. It is composed Full hardware design, which consumes almost no CPU power during encoding/decoding. but The diverse Image's format and the diverse moving picture's format is implemented software application with MPEG4 Codec(MP4).
In this dissertation, the author wants to tell that all implement's states and software appliction is scrutinized by author and the Digital Information Display(DID) solution is implemented directly by author with efforts and times. and The author think and believe that the Digital Information Display(DID) solution developes very fastly
Moving Human SCNT Research Forward Ethically
No full textA recent study of human somatic cells reprogrammed to a pluripotent state via somatic cell nuclear transfer (SCNT) will undoubtedly renew interest in human egg procurement. Thus it is imperative that human SCNT research move forward under stringent ethical standards in locales permitting directed egg donation for stem cell research
Allowing Innovative Stem Cell-Based Therapies outside of Clinical Trials: Ethical and Policy Challenges
No full textArmed with expanded federal funding for human embryonic stem cell research and new methods for deriving pluripotent stem cells, stem cell researchers in the U.S. are poised to proceed with unprecedented speed toward the development of new clinical therapies. Staring into the new dawn of regenerative medicine, many observers may assume that the only responsible route to the clinic, both scientifically and ethically, is through FDA-approved clinical trials processes. Conventional wisdom dictates that, like pharmaceutical drugs and the use of biological therapeutics, stem cell-based therapies will have to pass through a series of controlled studies — initially to assess safety and toxicity, then efficacy and comparative efficacy — before they can be justifiably administered to patients outside a clinical trials context.</jats:p
The bioethics of stem cell research and therapy
No full textDiscussion of the bioethics of human stem cell research has transitioned from controversies over the source of human embryonic stem cells to concerns about the ethical use of stem cells in basic and clinical research. Key areas in this evolving ethical discourse include the derivation and use of other human embryonic stem cell-like stem cells that have the capacity to differentiate into all types of human tissue and the use of all types of stem cells in clinical research. Each of these issues is discussed as I summarize the past, present, and future bioethical issues in stem cell research.http://dx.doi.org/10.1172/JCI4043
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