50 research outputs found

    Procedures and Properties for a Direct Nano-Micro Integration of Metal and Semiconductor Nanowires on Si Chips

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    1-dimensional metal and semiconductor nanostructures exhibit interesting physical properties, but their integration into modern electronic devices is often a very challenging task. Finding the appropriate supports for nanostructures and nanoscale contacts are highly desired aspects in this regard. In present work we demonstrate the fabrication of 1D nano- and mesostructures between microstructured contacts formed directly on a silicon chip either by a thin film fracture (TFF) approach or by a modified vapor-liquid-solid (MVLS) approach. In principle, both approaches offer the possibilities to integrate these nano-meso structures in wafer-level fabrications. Electrical properties of these nano-micro structures integrated on Si chips and their preliminary applications in the direction of sensors and field effect transistors are also presented

    Tin oxide nanowires suppress herpes simplex virus-1 entry and cell-to-cell membrane fusion.

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    The advent of nanotechnology has ushered in the use of modified nanoparticles as potential antiviral agents against diseases such as herpes simplex virus 1 and 2 (HSV-1) (HSV-2), human immunodeficiency virus (HIV), monkeypox virus, and hepatitis B virus. Here we describe the application of tin oxide (SnO(2)) nanowires as an effective treatment against HSV-1 infection. SnO(2) nanowires work as a carrier of negatively charged structures that compete with HSV-1 attachment to cell bound heparan sulfate (HS), therefore inhibiting entry and subsequent cell-to-cell spread. This promising new approach can be developed into a novel form of broad-spectrum antiviral therapy especially since HS has been shown to serve as a cellular co-receptor for a number of other viruses as well, including the respiratory syncytial virus, adeno-associated virus type 2, and human papilloma virus

    Nanonetworks: Rapid Fabrication Technique for Interpenetrated ZnO Nanotetrapod Networks for Fast UV Sensors (Adv. Mater. 10/2014)

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    Access full text - https://doi.org/10.1002/adma.201470061Flame transport synthesis (FTS) offers a unique fabrication technique for different nano-microtetrapods and their interconnected networks. Using the FTS method, interconnected ZnO nanotetrapod networks are fabricated directly bridging two patterned electrodes in a chip. It offers rapid and cost-effective synthesis with a direct integration of nano-microtetrapod networks in a chip, ready for device applications. Fast UV-detection response from these interconnected ZnO nanotetrapod networks is demonstrated by R. Adelung, Y. K. Mishra and co-workers on page 1541

    SnO<sub>2</sub> cytotoxicity determination.

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    <p>To determine the effect of SnO<sub>2</sub> nanowires on cell viability a cytotoxicity assay was performed. HCE were treated for 24 hours in the presence of SnO<sub>2</sub>. Cell viability was evaluated by a chromogenic kit (CellTiter Aqueous96; Promega, Madison, WI, USA) and colorimetric detections were performed using a mircroplate ELISA reader (Spectra Max 190). Results are expressed as 100% wild type (WT) viability where they represent the percent corrected absorbance after subtracting the background absorbance relative to untreated cells (0 µg/ml).</p

    Effect of Al Sn &#x2014; Doping on properties of zinc oxide nanostructured films grown by magnetron sputtering

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    Access full text - https://doi.org/10.1109/SMICND.2013.6688111Metal doping in nanostructured zinc oxide is important for device applications. To obtain improved performances for practical applications, Aluminum (Al) and Tin (Sn)-doping in zinc oxide nanostructured layers were investigated. Samples were grown by magnetron sputtering and studied by X-ray diffraction (XRD), micro-Raman, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) techniques. It was observed that nanoparticles are interconnected and form porous network of individual nanoparticles. It is found clear evidence of changes of different properties after doping with aluminum or tin in zinc oxide nanostructured films grown by magnetron sputtering

    Rapid Fabrication Technique for Interpenetrated ZnO Nanotetrapod Networks for Fast UV Sensors

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    Access full text - https://doi.org/10.1002/adma.201304363Two flame-based synthesis methods are presented for fabricating ZnO-nanostructure-based UV photodetectors: burner flame transport synthesis (B-FTS) and crucible flame transport synthesis (C-FTS). B-FTS allows rapid growth of ZnO nanotetrapods and in situ bridging of them into electrical contacts. The photo detector made from interconnected ZnO nanotetrapod networks exhibits fast response/recovery times and a high current ratio under UV illumination

    Rapid switching and ultra-responsive nanosensors based on individual shell–core Ga2O3/GaN:Ox@SnO2 nanobelt with nanocrystalline shell in mixed phases

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    Access full text - https://doi.org/10.1016/j.snb.2015.06.112The detailed TEM structural studies on the as-grown and annealed structures confirmed that the nanocable is made from mixed phases by an excellent agreement with the standard data for rutile SnO2, amorphous GaN:Ox and monoclinic β-Ga2O3. Herein, we resolve two essential problems regarding the nano-construction of an efficient nanosensor. First, the simplest process fabrication of the highly protected shell–core nanocables with improved electrical properties is achieved by cost-effective synthesis in a controlled manner. Second, construction of a non-planar 3D nanoscale double-heterojunctions with a large surface area is realized via an efficient technique. It allows surface protection of nanosensors during its fabrication and operation in different ambient conditions. The developed nanomaterial sparks interest for further studies on different hybrid semiconducting oxides as promising candidates for fabricating multifunctional nano- and micro-sensors and photodetectors

    SnO<sub>2</sub> inhibits HSV-1 entry into HCE cells.

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    <p>HCE cells were mock treated or treated with SnO<sub>2</sub> and exposed to HSV-1 at an MOI of 10 for 6 hours. A) After 6 hours of infection cells were washed, permeabilized and incubated with ONPG substrate for quantification of β-galactosidase activity from the viral genome. A dosage dependent decrease in entry was noted in cells as minimal entry occurred. B) X-gal staining of HCE cells. HCE cells grown in a 6-well plated were pretreated with SnO<sub>2</sub> before being challenged with HSV-1 for 6 hours. Cells were washed with PBS, fixed, permeabilized and incubated with X-gal, yielding blue cells. Infected cells were imaged at 10× objective using Zeiss Axiovert microscope. C) The average number of infected cells in SnO<sub>2</sub> treated cells is significantly lower than mock treated cells.</p
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