72 research outputs found
Estudo da utilização de meropenem e vancomicina nas enfermarias do Hospital Universitário da Universidade Federal de Santa Catarina.
No full textTrabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina. Departamento de Clínica Médica
Successful fibreoptic intubation via a laryngeal mask airway after failed extubation in an infant
No full textCompressive strength and sulfate resistance of limestone and/or silica fume mortars
No full textIn this study, compressive strength and sulfate resistance of mortars containing silica fume and/or limestone in different replacement levels were examined. For this purpose, limestone was used as 5%, 20%, 35% and silica fume was used as 5%, 10%, 15% by weight of cement. Sixteen different blended cements were prepared containing limestone and/or silica fume in different ratios. Mortar mixtures were prepared using these 16 cements. Flow values and 2, 7, 28, 90, 180 day-compressive strengths of the mortar mixtures were determined. In addition, sulfate resistances of mortars were separately determined in sodium and magnesium sulfate solutions. Consequently, it was seen that negative effect of silica fume on workability of mortars and limestone on compressive strength of mortars can be compensated by using limestone and silica fume together. Simultaneous use of limestone and silica fume was showed to increase sulfate resistance of mortars. (C) 2011 Elsevier Ltd. All rights reserved
Evaluation of Enzyme Immunoassay (EIA), Immunoblot and HIV RNA Polymerase Chain Reaction Test Results in the Diagnosis of Human Immunodeficiency Virus (HIV) Infection
No full textAcquired Immunodeficiency syndrome (AIDS) is an important global public health issue. Increasing HIV/AIDS cases reported each year has become a serious health problem for our country. The fourth generation enzyme immunoassay (EIA) test is the first step in the laboratory diagnosis of human immunodeficiency virus (HIV) infection. When the EIA test is repeatedly reactive, antibody-based tests such as immuno blot (IB), line immunoassay (LIA), HIV 1-2 antibody differentiation immunoassay, and HIV RNA tests for the early period of infection are used as confirmatory tests. The aim of this study was to evaluate the results of three different methods for the diagnosis of HIV infection. HIV 1-2 IB and quantitative HIV-1 RNA PCR tests were performed in 199 patient samples. These samples were detected as the reactive or gray zone with HIV 1-2 Ab+Ag EIA test between 2010 and 2015 at Akdeniz University Hospital, Microbiology Laboratory. HIV 1-2 Ab+Ag determination in serum samples was performed with the EIA method (Elecsys HIV combi PT test, Roche Diagnostics, Germany). A commercial kit (INNO-LIA HIV I-II Score, Innogenetics, Belgium) was used for HIV 1-2 IB method. The presence of HIV-1 RNA was investigated by automated nucleic acid extraction and real-time PCR method (Ampliprep/COBAS Tagman HIV-1 Test, Roche Diagnostics, Germany) in plasma samples. For statistical analysis, SPSS, Mann Whitney U test was used, ROC analysis was performed and p< 0.05 value was considered statistically significant. HIV 1-2 Ab+Ag EIA COI (cut-off index) median value was higher with positive HIV 1-2 IB and HIV-1 RNA results than negative HIV 1-2 IB and HIV-1 RNA results. These values were 394 (range: 11.5-2272) and 1.79 (range: 1.01-83.3) respectively and this difference was statistically significant (p< 0.001). HIV-1 RNA test results were positive in one patient with gray zone and two patients with negative HIV 1-2 IB result (viral loads were > 10.000.000, > 10.000.000 and 5.040.000 copies/ml, respectively). For the kit that we used for HIV 1-2 Ab+Ag EIA COI ratio of >16.45 had a sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 97.6%, 98.1%, 97.6% and 98.1%, respectively for the detection of HIV infection (r= 0.994, p< 0.001). HIV 1-2 Ab+Ag EIA S/CO ratio of < 9.26 had a sensitivity, specificity, PPV and NPV of 100%, 92.5%, 91.1% and 100% (p< 0.001). HIV infection is diagnosed if HIV 1-2 Ab+Ag EIA test result is repeatedly reactive and HIV 1-2 IB test and HIV-1 RNA tests are positive. In our study, HIV 1-2 Ab+Ag EIA COI median value was 394 (range: 11.5-2272) in this group of patients (p< 0.001). HIV-1 RNA PCR test was positive in three patients with > 10.000.000, 5.040.000 and > 10.000.000 copies/ml whose EIA tests were repeatedly reactive. HIV IB test was detected as the gray zone in one of them and as negative in the remaining two (HIV EIA S/CO values were 265, 9.5 and 131.8, respectively). These patients were diagnosed as acute HIV infection with clinical and laboratory findings. In conclusion, HIV RNA should also be performed and included in the diagnostic algorithm for acute HIV infection
Integrated Production and Transportation Scheduling Problem With Multiple Plants, Multiple Vehicles and Perishable Products
No full textThe integrated production and transportation scheduling problem is one of the interesting topics in the literature. This paper addresses Integrated Production and Transportation Scheduling Problems with Multiple Plants, Multiple Vehicles, and Perishable Products (PTSP-MP-MV). To the best of our knowledge, this problem has not been studied in the literature. In this problem, each plant has a different capacity and a different production rate. There is a single machine and a limited number of homogeneous vehicles in each plant. Each vehicle can be used more than once because of the vehicle capacity and planning horizon restrictions. Only one type of product is produced, and this product has a limited lifespan. The objective of the problem is to minimize the total cost including production, distribution, and vehicle costs. We propose a mixed integer programming (MIP) formulation for the problem and strengthen it with several valid inequalities to improve lower bounds. The performance of the formulation is calculated using a newly generated set of test instances. Computational results show that small-sized instances with 5 and 10 customers can be solved optimally in less than 90 s. Satisfactory results are obtained for the test instances up to 20 customers whose optimality gap values are calculated as 0.54% nearly 1 h. It is also shown that the valid inequalities are improved lower bounds about 3%. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.Acknowledgements. This study is derived from the author Gozde CAN ATASA-GUN’s PhD thesis entitled “The Coordinated Production and Transportation Scheduling Problem with Multiple Plants and Multiple Vehicles” (Supervisor: Prof. Dr. Ismail KARAOGLAN) which is supported by Konya Technical University Coordinatorship of Scientific Research Projects with the project number of 18101021 and has not been published elsewhere.Konya Teknik Üniversitesi, KTÜN: 1810102
Usage of steel slag in concrete as fine and/or coarse aggregate
No full textIn this study, the use of steel slag as fine and/or coarse aggregate in concrete is investigated. For this purpose, 12 different concrete mixtures with different water/cement ratios of 0.40, 0.55 and 0.70 which include steel slag aggregate as fine and/or coarse aggregate are prepared. Compressive strength, split tensile strength, flexural strength, freeze-thaw resistance and water penetration depth of concrete mixtures containing steel slag aggregate are examined in comparison with concrete mixtures prepared by using crushed limestone aggregate. Eventually, concrete mixtures containing coarse steel slag show better performance than concrete mixtures containing limestone aggregate. Concrete mixtures containing fine steel slag show worse performance in comparison with concrete mixtures containing limestone aggregate
The effect of cylindrical specimen size on the compressive strength of concrete
No full textIn this study, the influence of size and capping type of cylindrical specimens on compressive strength of concrete is investigated. For this purpose, eight series of concrete mixtures were designed to have water/cement ratios of 37%, 42%, 47%, 48%, 55%, 62%, 71% and 77% (by volume). Three hundred and eighty-four cylindrical specimens having dimensions of 150/300 and 120/200 mm were casted. At the end of 28-day standard curing period, the uniaxial compressive strength of capped and uncapped specimens was determined. Cement, gypsum and sulphur are used as capping materials. The results of the experimental study reveal that the suitable average conversion factor (the ratio of compressive strength of 100/200 mm cylinder to 150/300 mm cylinder f(c100)/f(c150)) can be taken as 103%. Linear and nonlinear regression analyses were employed between f(c100) and f(c150). Linear and nonlinear regression analyses exhibited better performance. (c) 2006 Elsevier Ltd. All rights reserved
Usage of steel slag in concrete as fine and/or coarse aggregate
No full textIn this study, the use of steel slag as fine and/or coarse aggregate in concrete is investigated. For this purpose, 12 different concrete mixtures with different water/cement ratios of 0.40, 0.55 and 0.70 which include steel slag aggregate as fine and/or coarse aggregate are prepared. Compressive strength, split tensile strength, flexural strength, freeze-thaw resistance and water penetration depth of concrete mixtures containing steel slag aggregate are examined in comparison with concrete mixtures prepared by using crushed limestone aggregate. Eventually, concrete mixtures containing coarse steel slag show better performance than concrete mixtures containing limestone aggregate. Concrete mixtures containing fine steel slag show worse performance in comparison with concrete mixtures containing limestone aggregate.Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [107M607]This study was funded by the Scientific and Technological Research Council of Turkey (Project number: 107M607)
Investigation of sulfate resistance and alkali silica reaction in polymer-incorporating mortars
No full textBu çalışmada, polimer ilaveli harçların sülfat etkisine ve alkali silika reaksiyonuna karşı direnci incelenmiştir. Bu amaçla, bağlayıcı olarak normal portland çimentosu ve stiren-akrilik polimer emülsiyonu kullanılmıştır. Polimer ağırlıkça %0, 5, 10 ve 15 oranlarında çimento yerine ikame edilerek harç karışımları hazırlanmıştır. Hazırlanan harç örneklerinin 28 günlük basınç ve eğilme dayanımları, kılcal yolla su emme, porozite, birim ağırlık gibi özellikleri belirlenmiştir. Ayrıca harç karışımlarının ASTM C1012 standardına göre sülfat direnci, ASTM C1260 standardına göre alkali silis reaksiyonuna karşı direnci saptanmıştır. Polimer ilaveli harçlarda elde edilen sonuçlar kontrol harcı ile kıyaslamalı olarak değerlendirilmiştir.In this study, sulfate resistance and alkali silica reaction in mortars incorporating polymer were investigated. In this aim, normal portland cement and styrene-acrylic polymer emulsion were used. Mortar mixtures were prepared by replacing cement, with 0, 5, 10 and 15% polymer, by weight. 28-days compressive and flexural strength, water absorption and water sorptivity, porosity and unit weight of prepared mortar specimens were determined. Besides, sulfate resistance and alkali silica reaction resistance of prepared mortar mixtures were determined according to ASTM C1012 and ASTM C1260, respectively. Results obtained in polymeric mortar mixtures were comparatively evaluated with control mortar mixture
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