169,719 research outputs found
Rat liver ornithine decarboxylase and SGP-2 mRNAs respond with opposite changes to surgical stress
No full textSGP-2, APOPTOSIS, AND AGING
No full textThe activation of a Calcium, Magnesium-dependent endogenous endonuclease that cuts DNA into discrete multiples of a nucleosomal unit seems to play a pivotal role during apoptosis. One of the early events following the activation of the cell death program is the increase in intracellular calcium. This is very similar to what happens during the early steps of cellular proliferation. Induction of c-fos and c-myc oncogenes seems to be another feature shared by these two opposite phenomena. To test this hypothesis we focused our attention on the expression of sulfated glycoprotein 2 mRNA in several systems undergoing cell death, cell proliferation, or aging process
Levels of SGP-2, ornithine decarboxylase (ODC) and glyceraldehyde phosphate dehydrogenase (GAPDH) mRNAs in several tissues of the aging rat
No full textOpposite pattern of Sulfated Glycoprotein 2 (SGP-2) and Ornithine Decarboxylase mRNAs accumulation in PHA-stimulated human lymphocytes
No full textLevels of ornithine decarboxylase and SGP-2 mRNAs in serum stimulated human fibroblasts at different stages of growth
No full textStudies on the relationship between cell proliferation and cell death: apposite patterns of SGP-2 and ornithine decarboxylase mRNA accumulation in PHA-stimulated human limphocytes
No full textLevels of sulphated glycoprotein-2, glyceraldehyde-3-phosphate dehydrogenase and ornithine decarboxylase mRNAs in several organs of the aging rat
No full textTHE GENE FOR SP-40,40, HUMAN HOMOLOG OF RAT SULFATED GLYCOPROTEIN-2, RAT CLUSTERING, AND RAT TESTOSTERONE-REPRESSED PROSTATE MESSAGE-2, MAPS TO CHROMOSOME-8
No full textThe mapping data and the Southern analysis presented in the paper strongly suggest tha in the human genome there is a single locus coding for the protein which has been called, in different species, SP-40,40, SGP-2, clusterin, and TRPM-2
STUDIES ON THE RELATIONSHIP BETWEEN CELL-PROLIFERATION AND CELL-DEATH - OPPOSITE PATTERNS OF SGP-2 AND ORNITHINE DECARBOXYLASE MESSENGER-RNA ACCUMULATION IN PHA-STIMULATED HUMAN-LYMPHOCYTES
No full textTo assess the relationship between cell proliferation and cell death, the mRNA accumulation of ornithine decarboxylase (ODC)and sulfated glycoprotein 2 (SGP-2) were measured in human peripheral blood lymphocytes (HPBL), 2-6 hours after stimulation with phytohemoagglutinin (PHA). A consistent amount of SGP-2 mRNA in quiescent HPBL, an early and progressive decrease of SGP-2 mRNA and a parallel increase of ODC mRNA accumulation, were observed, in PHA-stimulated HPBL, suggesting that concomitant repression of SGP-2 and induction of ODC genes contribute for the cell entering the cell cycle
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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