46 research outputs found
Characterization of dissolved organic matter using high-performance liquid chromatography (HPLC)-size exclusion chromatography (SEC) with a multiple wavelength absorbance detector
No full textHigh-performance liquid chromatography-size exclusion chromatography (HPLC-SEC) coupled with a multiple wavelength absorbance detector (200-445 nm) was used in this study to investigate the apparent molecular weight (AMW) distributions of dissolved organic matter (DOM). Standard DOM, namely humic acid, fulvic acid and hydrophilic acid, from the Suwannee River were tested to ascertain the performance and sensitivity of the method. In addition to four compounds groups: humic substances (Peak 1, AMW 16 kD), fulvic acids (Peak 2, AMW 11 kD), low AMW acids (Peak 3, AMW 5 kD), and low AMW neutral and amphiphilic molecules, proteins and their amino acid building blocks (Peak 4, AMW 3 kD), an new group that appears to include low AMW, 6-10 kD, humic substances was found based on investigating the spectra at various elution times. The spectroscopic parameter S->365 (slope at wavelengths >365 nm) was determined to be a good predictor of the AMW of the DOM. The detector wavelength played an important role in evaluating the AMW distribution. For some fractions, such as the humic and low AMW non-aromatic substances, the error in measurement was +/- 30% as determined by two-dimensional chromatograms detected at an artificially selected wavelength. HPLC-SEC with multiple wavelength absorbance detection was found to be a useful technique for DOM characterization. It characterized the AMW distributions of DOM more accurately and provided additional, potentially important information concerning the properties of DOM with varying AMWs. (C) 2012 Elsevier Ltd. All rights reserved
Characterising hyperbolic hyperplanes of a non-singular quadric in PG (4, q)
No full textLet H be a non-empty set of hyperplanes in PG(4,q), q even, such that every point of PG(4,q) lies in either 0, 1/2q³ or 1/2(q³+q²²) hyperplanes of H, and every plane of PG(4,q) lies in 0 or at least 1/2q hyperplanes of H. Then H is the set of all hyperplanes which meet a given non-singular quadric Q(4, q) in a hyperbolic quadric.S.G. Barwick, Alice M.W. Hui, Wen-Ai Jackson, Jeroen Schillewaer
Jak uczyć stosunków międzynarodowych? Praktyka podróży studyjnej w ramach kierunku Stosunki Międzynarodowe na Akademii Marynarki Wojennej w latach 2016−2019
No full textThe article concerns study trips organised by the Faculty of International Relations of the Polish Naval Academy (Akademia Marynarki Wojennej – AMW) between 2016 and 2019. The text consists of four parts. The first part outlines the theoretical approach to study trips as a teaching technique particularly useful in the study of international relations. A model of a study trip organised by AMW is presented. In the second part, the case studies of six study trips implemented by AMW are discussed and analysed. In the third part, the authors criticise study trips as a teaching tool used under the conditions of the Polish higher education system. In the final part, the author suggests institutionalising study trips. In the authors’ opinion, they can become a new distinguishing feature of education in the Polish higher education system, responding to the challenges of the globalising world
Jak uczyć stosunków międzynarodowych? Praktyka podróży studyjnej w ramach kierunku Stosunki Międzynarodowe na Akademii Marynarki Wojennej w latach 2016−2019
No full textThe article concerns study trips organised by the Faculty of International Relations of the Polish Naval Academy (Akademia Marynarki Wojennej – AMW) between 2016 and 2019. The text consists of four parts. The first part outlines the theoretical approach to study trips as a teaching technique particularly useful in the study of international relations. A model of a study trip organised by AMW is presented. In the second part, the case studies of six study trips implemented by AMW are discussed and analysed. In the third part, the authors criticise study trips as a teaching tool used under the conditions of the Polish higher education system. In the final part, the author suggests institutionalising study trips. In the authors’ opinion, they can become a new distinguishing feature of education in the Polish higher education system, responding to the challenges of the globalising world
Targeting WDR5: A WINning Anti-Cancer Strategy?
No full textWDR5 is a component of multiple epigenetic regulatory complexes, including the mixed lineage leukemia (MLL)/SET complexes that deposit histone H3 lysine 4 methylation. Inhibitors of an arginine-binding cavity in WDR5, known as the WDR5-interaction (WIN) site, have been proposed to selectively kill MLL-rearranged malignancies via an epigenetic mechanism. We discovered potent WIN site inhibitors and found that they kill MLL cancer cells not through changes in histone methylation. but by displacing WDR5 from chromatin at protein synthesis genes, choking the translational capacity of these cells, and inducing death via a nucleolar stress response. The mechanism of action of WIN site inhibitors reveals new aspects of WDR5 function and forecasts broad therapeutic utility as anti-cancer agents.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors disclose receipt of the following financial support for the research, authorship, and/or publication of this article: National Cancer Institute, National Institutes of Health (HHSN261200800001E to SFW; CA200709 to WPT; CA119925 to ERA and AMW); Robert J. Kleberg, Jr., and Helen C. Kleberg Foundation (to SWF and WPT), Alex's Lemonade Stand Foundation (WPT), Edward P. Evans Foundation (WPT); Rally Foundation for Childhood Cancer Research Fellowship (AMW), Open Hands Overflowing Hearts co-funded research fellowship (AMW), the American Association for Cancer Research Basic Cancer Research Fellowship (AMW)
Acute effects of sprint interval training and blood flow restriction on neuromuscular and muscle function
No full textDHGR, AMW, ECH, MSS and JRS conceived the study concept and design. DHGR, AMW, PMR and CEP carried out data acquisition. DHGR performed data analysis and was the primary author. AMW, PMR, CEP, JEL, MSS, JRS, FB, and ECH aided in manuscript development and editing. All authors approved the final version of this manuscriptBFR) applied during sprint interval training (SIT) on performance and neuromuscular function.
Methods: Fifteen men completed a randomized bout of SIT with CBFR, IBFR, and without BFR (No-BFR), consisting of 2, 30-s maximal sprints on a cycle ergometer with a resistance of 7.5% of body mass. Concentric peak torque (CPT), maximal voluntary isometric contraction (MVIC) torque, and muscle thickness (MT) were measured before and after SIT, including surface electromyography (sEMG) recorded during the strength assessments. Peak and mean revolutions per minute (RPM) were measured during SIT and power output was examined relative to physical working capacity at the fatigue threshold (PWCFT).
Results: CPT and MVIC torque decreased from pre-SIT (220.3±47.6 Nm and 355.1±72.5 Nm, respectively) to post-SIT (147.9±27.7 Nm and 252.2±45.5 Nm, respectively, all P<0.05), while MT increased (1.77±0.31 cm to 1.96±0.30 cm). sEMG mean power frequency decreased during CPT (-12.8±10.5%) and MVIC (-8.7±10.2%) muscle actions. %PWCFT was greater during No-BFR (414.2±121.9%) than CBFR (375.9±121.9%).
Conclusion: SIT with or without BFR induced comparable alterations in neuromuscular fatigue and sprint performance across all conditions, without affecting neuromuscular function
Okrętowe stale specjalne i osłony konstrukcyjno-balistyczne opracowane w AMW
No full textIn order to increase security of the country in the field of new materials and technologies and research methods were developed, patented and implemented: austenitic steel X02CrNiMoMnN21-16-5-4 with electrodes for welding of steel and high-strength bainitic steel 10GHMBA-E620T. The author developed a theoretical and technological basis for the design of marine constructional-ballistic shields, which has implemented a pilot scale and technical support. In addition, he developed an original method for testing ballistic shields and unified position to the research, which studied and co-patented.Dla wzrostu bezpieczeństwa kraju w zakresie nowych materiałów i technologii oraz metod badawczych opracowano, opatentowano i wdrożono: stal austenityczną X02CrNiMoMnN21-16-5-4 wraz z elektrodami do spawania tej stali oraz wysokowytrzymałą stal bainityczną gat. 10GHMBA-E620T. Autor opracował teoretyczne i technologiczne podstawy projektowania okrętowych osłon konstrukcyjno-balistycznych, które wdrożył w skali półtechnicznej i technicznej. Ponadto opracował oryginalną metodę badania odporności balistycznej osłon oraz zunifikowane stanowisko do badań, które przebadał i współopatentował
Sustainable Tourism Development Appraisal in Various Regions of Poland
No full textTourism has its functions and dysfunctions for the reception region. The purpose of the study is to state which of Polish regions can be characterized as the areas of sustainable tourism reception. To achieve the aim of the study the following hypothesis was put forward: voivodships of northern and southern Poland were the areas of sustainable tourism reception in 2015. The examination of the sustainable tourism should take into consideration both positive and negative influence of tourism on the environment and society; that is why the taxonomic measure of development was employed. The study included variables concerning tourism directly as well as those connected indirectly with its development in the given area. Regarding the substantive criteria of variables’ selection the author considered the state of the art in tourism and economic sciences. The conducted research indicated that some of regions in Poland can be recognized as the sustainable tourism reception regions.Celem artykułu jest określenie, na terenie których polskich województw turystyka najlepiej spełnia kryteria zrównoważonego rozwoju. Aby zrealizować cel badawczy, postawiono hipotezę, która brzmi: „Obszarami recepcji turystyki zrównoważonej w 2015 roku były województwa położone na północy i południu Polski”. Badanie turystyki zrównoważonej musi brać pod uwagę zarówno pozytywny, jak i negatywny wpływ tej gałęzi gospodarki na środowisko i społeczeństwo, dlatego aby zweryfikować hipotezę badawczą, zastosowano taksonomiczny miernik rozwoju. W badaniu uwzględniono zmienne stricte dotyczące turystyki oraz te związane pośrednio z jej rozwojem na danym terenie. W kwestii kryteriów merytorycznych doboru zmiennych brano pod uwagę stan wiedzy w obszarze nauk o turystyce i nauk ekonomicznych. Przeprowadzona analiza wykazała, że część polskich województw może zostać uznana za obszary recepcji turystyki zrównoważonej
Martial arts fiction : translational migrations east and west
No full textThis thesis was motivated by Robert Chard's puzzlement over the translational
phenomenon of martial arts fiction in the West. It proposes to address how the
translational migration of martial arts fiction took place, first to other Asian countries in the
1920's, but to the West only after a lapse of a few decades beginning in the early 1990's.
Adopting a descriptive approach as described by Gideon Toury, the thesis is intended to
add further to the limited inventory of case studies in urgent demand to test the polysystem
theory propounded by Even-Zohar.
The thesis is made up of two parts. Part I is a macro-level study of martial arts fiction,
intended to contribute to testing the limits of the polysystem theory. After examining
Chinese fiction as a low form in the Chinese literary polysystem and its weak function as
translated literature in the Western literary polysystem, the study explores the translational
phenomenon of martial arts fiction in the West as well as the concurrent phenomenon as to
why so little of martial arts fiction has been translated into Western languages, compared to
the copious amount into other Asian languages, to the extent of stimulating a new literary
genre or (re)writing martial arts fiction in indigenous languages in Indonesia, Vietnam and
Korea, sinicized countries or countries boasting large overseas Chinese communities.
Issues and problems related to these translational activities and cultural phenomena are
presented as tools to test the limits of the polysystem theory.
Part II is a micro-level study focussing on the specifics of rendering Fox Volant of the
Snowy Mountain by Jin Yong into English. I will argue, in the main, that many difficulties,
inherent in both the translating and reading processes, can be constructed within the
theoretical framework of Andre Lefevere's concept of "constraint", particularly that of the
universe of discourse. Lefevere's connotation of the universe of discourse will be expanded
to embrace different cultural presuppositions and literary assumptions underlying two
divergent world cultures, hence different reader expectations in the reading process.
It is hoped that the findings and results of this descriptive case history of martial arts fiction
as a literary genre in translational migrations will contribute to the accumulation of
knowledge
