173 research outputs found
1.23 Ga mafic dykes in the North China Craton and their implications for the reconstruction of the Columbia supercontinent
No full textAbstract not availableWei Wang, Shuwen Liu, M. Santosh, Lifei Zhang, Xiang Bai, Yue Zhao, Shuanhong Zhang, Rongrong Gu
[[alternative]]A Study on a Psychotherapist’s Countertransference during the Process of Psychotherapy
No full text[[abstract]]A Study on a Psychotherapist’s Countertransference during the Process of Psychotherapy
Pey-Ling Shieh
Abstract
The purpose of this study is to explore the countertransference during an ongoing process of psychotherapy. The study is conducted by the phenomenology approach. As a ten-session psychotherapy progressed, the psychotherapist was interviewed within 30 hours after each session. The data were analyzed by a framework retrieved from the data itself. The contextual factors, natures and transformation of the countertransference were all described.
The result yielded 22 units of countertransference experience. When compared with contextual factors, the psychotherapist’s countertransference to the specific client was found to have dual implications and to be more various than her original definition of and previous experiences of countertransference. The related factors of countertransference consisted of the fixed background of the therapist as well as the unique portion of the therapist-client interaction. The four domains of countertransference were classified as ‘feelings or cognitions toward the client’, ‘the role and position of the therapist and psychotherapy’, ’relationship and therapy maintenance’ and ‘distraction with associations’.
Most units of countertransference fall into the category of ‘Feelings or cognitions toward the client’. The therapist had various feelings toward the client and some of those feeling led to cognitions about the client. ‘Role and position of the therapist and psychotherapy’ is the second most frequent category of the countertransference, which happened when the therapist wondered about ‘what is the role of a therapist’ and ’what is the position of psychotherapy’. The feeling of being used and of not being respected would contribute to the discontinuity of therapy. As for the countertransference of ’relationship and therapy maintenance’, therapist’s assessment of the relationship was directly related to the maintenance of therapy. On ‘distraction with associations’, the therapist experienced various association and identification.
During the process of the psychotherapy, the familiarity of the therapist with the client increased. The global trend of understanding moved from stereotype-based and experience-based toward specific issues of the client. The focus of hypotheses-testing moved from ‘content consistency between client’s story and therapist’s experience’ toward ’internal consistency within client’s aspects of story’ or ’consistency between client’s story and hypotheses’. The transformation between sessions fluctuated and was recurrent. All four domains occurred at the initial stage and were intertwined with each other throughout the psychotherapy. process.
Given the findings that the countertransference displayed various natures and was formed by multiple factors, the author suggests some directions about future training and research.
Keywords: countertransference, process of psychotherapy, phenomenology
Dante\u27s Virgils
No full textThe questions brought to a text define the reading of it, questions both invited by the author and assumed by the reader. Dante\u27s Divine Comedy opens with a remarkable ambiguity that calls for an investigation of the questions being brought to the poem:
Midway along the journey of our lifeI woke to find myself in a dark wood,For I had wandered off from the straight path. (Inf 1.1-3)
CD11a regulates hematopoietic stem and progenitor cells
No full textIntegrin αLβ2 (CD11a/CD18, CD11a) is a critical leukocyte adhesion molecule in leukocyte arrest and immunological synapse formation. However, its role in the bone marrow has not been investigated in depth. Here we showed that CD11a was expressed on all subsets of hematopoietic stem and progenitor cells (HPSCs). CD11a deficiency enhanced HSPCs activity under lipopolysaccharide (LPS) stimulation as demonstrated by a higher HSPC cell count along with an increase in cell proliferation. However, our mixed chimera experiment did not support that this phenotype was driven in a cell-intrinsic manner. Rather we found that the production of IL-27, a major cytokine that drives HSPC proliferation, was significantly upregulated both in vivo and in vitro. This adds a novel role of CD11a biology
A Spatial Control for Correct Timing of Gene Expression during the Escherichia coli Cell Cycle
No full textabstract: Temporal transcriptions of genes are achieved by different mechanisms such as dynamic interaction of activator and repressor proteins with promoters, and accumulation and/or degradation of key regulators as a function of cell cycle. We find that the TorR protein localizes to the old poles of the Escherichia coli cells, forming a functional focus. The TorR focus co-localizes with the nucleoid in a cell-cycle-dependent manner, and consequently regulates transcription of a number of genes. Formation of one TorR focus at the old poles of cells requires interaction with the MreB and DnaK proteins, and ATP, suggesting that TorR delivery requires cytoskeleton organization and ATP. Further, absence of the protein–protein interactions and ATP leads to loss in function of TorR as a transcription factor. We propose a mechanism for timing of cell-cycle-dependent gene transcription, where a transcription factor interacts with its target genes during a specific period of the cell cycle by limiting its own spatial distribution
Anti-Inflammatory and Immunoregulatory Functions of Artemisinin and Its Derivatives
No full textArtemisinin and its derivatives are widely used in the world as the first-line antimalarial drug. Recently, growing evidences reveal that artemisinin and its derivatives also possess potent anti-inflammatory and immunoregulatory properties. Meanwhile, researchers around the world are still exploring the unknown bioactivities of artemisinin derivatives. In this review, we provide a comprehensive discussion on recent advances of artemisinin derivatives affecting inflammation and autoimmunity, the underlying molecular mechanisms, and also drug development of artemisinins beyond antimalarial functions
DataSheet_1_CD11c regulates late-stage T cell development in the thymus.docx
No full textCD11c, also named integrin αX, has been deemed solely as a dendritic cell marker for decades while the delineation of its biological function was limited. In the current study, we observed in mice that CD11c deficiency led to a defect in T cell development, demonstrated by the loss of CD4+CD8+ double positive (DP) T cells, CD4+CD8-, and CD4-CD8+ single positive (SP) T cells in the thymus and less mature T cells in the periphery. By using bone marrow chimera, we confirmed that CD11c regulated T cell development in the thymus. We further showed that CD11c deficiency led to an accelerated apoptosis of CD3 positive thymocytes, but not CD4-CD8- double negative (DN) T cells. Overall, this study added one more layer of knowledge on the regulatory mechanism of late-stage T cell development that the presence of CD11c in the thymus is critical for maintaining T cell survival.</p
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