51 research outputs found
Study of 13-17th century Marathi manuscripts: author generated metadata and its mapping with Dublin Core
No full textThis paper reports on a study that examined the author generated metadata for 13th–17th century manuscripts. For the study 30 different handwritten Marathi (local language of Maharashtra State, India) manuscripts by Marathi poet saints were analyzed critically especially the start and end note areas (colophon area) from which one can easily identify the author, subject, geographical area, time period of the manuscript, etc. An attempt is made to map these author-generated metadata with Dublin Core elements set. Translated DC elements into Marathi are also used for mapping purpose. The results indicate that authors created good quality metadata to classify the manuscript easily. This research suggests that metadata created by poet saints from 13th–17th century can be easily mapped with DC elements. There are key metadata elements found in manuscripts that need to be incorporated. The study is very significant as the digitization of these manuscripts is under progress and the basic metadata will be useful for "resource discovery" once the data will be made available on the Internet
Analysis of physics research output of SP Pune University during the period 1990-2014
No full text106-112The paper analyzes the research contributions by the faculty members of the Department of Physics, Savitribai Phule Pune University (SPPU), Pune, Maharashtra, India for the period 1990-2014. Bibliographic and citation data were retrieved from Scopus database. Query statements covering all variations in the name of SPPU were used to search the database. Scopus indexed 1629 publications with 22618 citations for the period. Author keywords in Scopus database indicate that faculty members are working in core areas of physics as well as interdisciplinary subjects like chemistry, instrumentation sciences, engineering, etc. The year-wise analysis shows that research productivity of faculty member increased over the period. Faculty members published their research in core physics journals among which Journal of Applied Physics (72 papers) is the most preferred journal. The faculty members of the University have collaborated with scientists from USA, UK, Germany and Japan. At the national level, the University physicists have collaborated most with Bhabha Atomic Research Centre
Pulse Oximetry Accuracy in Children with Dark Skin Tones: Relevance to Acute Lower Respiratory Infection Care in Low- and Middle-Income Countries
No full textAcute lower respiratory infections (ALRI) are the leading post-neonatal cause of death in children under 5 years old. There is a high prevalence of pediatric ALRI-related hypoxemia in low- and middle-income countries. The WHO defines clinically meaningful hypoxemia in children as a SpO2 (peripheral oxygen saturation) \u3c 90%. Multiple studies put this convention into question and found SpO2 of 90% to 92% to be associated with child ALRI mortality. An evolving body of evidence suggests that pulse oximeters systematically overestimate oxygen saturation in individuals with dark skin tones. We conducted a narrative review of pediatric studies evaluating pulse oximeter accuracy in children without COVID-19. Four studies, one prospective, examined pulse oximeter accuracy in children of varying ages with dark skin tones. All studies had limitations that affect their generalizability. There is evidence that certain pulse oximeters may overestimate oxygen saturation in children with dark skin tones. Further prospective research is urgently needed to identify affected populations and clinical implications. Despite recognized challenges, we strongly urge continued and expanded use of pulse oximetry as its use will save lives
Pulse Oximetry Accuracy in Children with Dark Skin Tones: Relevance to Acute Lower Respiratory Infection Care in Low- and Middle-Income Countries
No full textAcute lower respiratory infections (ALRI) are the leading post-neonatal cause of death in children under 5 years old. There is a high prevalence of pediatric ALRI-related hypoxemia in low- and middle-income countries. The WHO defines clinically meaningful hypoxemia in children as a SpO2 (peripheral oxygen saturation) <90%. Multiple studies put this convention into question and found SpO2 of 90% to 92% to be associated with child ALRI mortality. An evolving body of evidence suggests that pulse oximeters systematically overestimate oxygen saturation in individuals with dark skin tones. We conducted a narrative review of pediatric studies evaluating pulse oximeter accuracy in children without COVID-19. Four studies, one prospective, examined pulse oximeter accuracy in children of varying ages with dark skin tones. All studies had limitations that affect their generalizability. There is evidence that certain pulse oximeters may overestimate oxygen saturation in children with dark skin tones. Further prospective research is urgently needed to identify affected populations and clinical implications. Despite recognized challenges, we strongly urge continued and expanded use of pulse oximetry as its use will save lives
Characteristics and outcomes of children initiated on high flow nasal cannula and continuous positive airway pressure at the emergency centre of a district hospital in South Africa
No full textIntroduction: High-flow nasal cannula (HFNC) and continuous positive airway pressure delivered via a nasal interface (nCPAP) are increasingly used for paediatric emergency care in South Africa. In Cape Town, initiation of HFNC/nCPAP at a district hospital, in most instances, necessitates transfer to a paediatric high-care facility. We sought to describe the population of children initiated on HFNC/nCPAP and their short-term hospital outcomes post interfacility transfer. Methods: The authors conducted a one-year retrospective observational study between August 1st 2021, to July 31st, 2022 of children initiated on HFNC or nCPAP in the emergency centre (EC) of Khayelitsha district Hospital and transferred by ambulance to Tygerberg Hospital paediatric emergency centre. Children were excluded from the study if they were 13 years of age, if they had an advanced care plan that restricted the escalation of respiratory support or if their medical records were incomplete. Results: At Khayelitsha Hospital, 117 patients were initiated on HFNC (n = 58) or nCPAP (n = 59). Participants had a median age of 6.8 months. There were no major adverse events reported during inter-facility transfer. Respiratory support was weaned to low flow oxygen or room air within 24 h of transfer in 23.9 % and escalated in 9.4 %. During hospital stay 14.5 % were admitted to intensive care, 6.0 % ultimately required mechanical ventilation, and the in-hospital mortality rate was 1.7 %. Conclusion: Roughly a quarter of patients were weaned from respiratory support within 24 h of transfer. Short term outcomes were good overall, demonstrating safe interfacility transfer and low mortality. Further research is needed to inform practice on best use of HFNC and nCPAP in the emergency care of children presenting with acute respiratory illness in South Africa
Implication of the 2014 World Health Organization Integrated Management of Childhood Illness Pneumonia Guidelines with and without pulse oximetry use in Malawi: A retrospective cohort study
No full textBACKGROUND: Under-5 pneumonia mortality remains high in low-income countries. In 2014 the World Health Organization (WHO) advised that children with chest indrawing pneumonia, but without danger signs or peripheral oxygen saturation (SpO 2) < 90% be treated in the community, rather than hospitalized. In Malawi there is limited pulse oximetry availability. METHODS: Secondary analysis of 13,413 under-5 pneumonia cases in Malawi. Pneumonia associated case fatality ratios (CFR) were calculated by disease severity under the assumptions of the 2005 and 2014 WHO Integrated Management of Childhood Illness (IMCI) guidelines, with and without pulse oximetry. We investigated if pulse oximetry readings were missing not at random (MNAR). RESULTS: The CFR of patients classified as having non-severe pneumonia per the 2014 IMCI guidelines doubled under the assumption that pulse oximetry was not available (1.5% without pulse oximetry vs 0.7% with pulse oximetry, P<0.001). When 2014 IMCI guidelines were applied with pulse oximetry and a SpO 2 < 90% as the threshold for referral and/or admission, the number of cases meeting hospitalization criteria decreased by 70.3%. Unrecorded pulse oximetry readings were MNAR with an adjusted odds for mortality of 4.9 (3.8, 6.3), similar to that of a SpO 2 < 90%. Although fewer girls were hospitalized, female sex was an independent mortality risk factor. CONCLUSIONS: In Malawi, implementation of the 2014 WHO IMCI pneumonia guidelines, without pulse oximetry, will miss high risk cases. Alternatively, implementation of pulse oximetry may result in a large reduction in hospitalization rates without significantly increasing non-severe pneumonia associated CFR if the inability to obtain a pulse oximetry reading is considered a WHO danger sign
Analysis of physics research output of SP Pune University during the period 1990-2014
No full textThe paper analyzes the research contributions by the faculty members of the Department of Physics, Savitribai Phule Pune University (SPPU), Pune, Maharashtra, India for the period 1990-2014. Bibliographic and citation data were retrieved from Scopus database. Query statements covering all variations in the name of SPPU were used to search the database. Scopus indexed 1629 publications with 22618 citations for the period. Author keywords in Scopus database indicate that faculty members are working in core areas of physics as well as interdisciplinary subjects like chemistry, instrumentation sciences, engineering, etc. The year-wise analysis shows that research productivity of faculty member increased over the period. Faculty members published their research in core physics journals among which Journal of Applied Physics (72 papers) is the most preferred journal. The faculty members of the University have collaborated with scientists from USA, UK, Germany and Japan. At the national level, the University physicists have collaborated most with Bhabha Atomic Research Centre
Correction: Predicting Hospitalised Paediatric Pneumonia Mortality Risk: An External Validation of RISC and mRISC, and Local Tool Development (RISC-Malawi) from Malawi
No full textHypoxaemia and Risk of Death Among Children: Rethinking Oxygen Saturation, Risk-Stratification, and the Role of Pulse Oximetry in Primary Care
No full textPulse oximeters are essential for assessing blood oxygen levels in emergency departments, operating theatres, and hospital wards. However, although the role of pulse oximeters in detecting hypoxaemia and guiding oxygen therapy is widely recognised, their role in primary care settings is less clear. In this Viewpoint, we argue that pulse oximeters have a crucial role in risk-stratification in both hospital and primary care or outpatient settings. Our reanalysis of hospital and primary care data from diverse low-income and middle-income settings shows elevated risk of death for children with moderate hypoxaemia (ie, peripheral oxygen saturations [SpO2] 90–93%) and severe hypoxaemia (ie, SpO2 \u3c90%). We suggest that moderate hypoxaemia in the primary care setting should prompt careful clinical re-assessment, consideration of referral, and close follow-up. We provide practical guidance to better support front-line health-care workers to use pulse oximetry, including rethinking traditional binary SpO2 thresholds and promoting a more nuanced approach to identification and emergency treatment of the severely ill child
Communities Disproportionately Affected by Carbon Monoxide Exposure After Winter Storm Uri
No full textExtreme cold in February 2021 precipitated prolonged power failure in Texas. In Houston, many patients presented for carbon monoxide exposure from neighborhoods with lower per capita income, higher rates of limited English proficiency, and greater median Social Vulnerability Indices than Greater Houston. Weather-related disasters disproportionately affect socially vulnerable communities
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