10,121 research outputs found
Anne as Pagan, Anne as Queer
No full text‘Anne as Pagan, Anne as Queer’ is a critical and creative answer to the question: How do we construct Anne Shirley, and what does she mean to us? This creative research submission is a work of fanfiction, specifically a mash up based on Anne of the Island, L.M.M. Montgomery’s sequel to Anne of Green Gables. In this short work of fiction (under 4 thousand words) Anne is revealed as a changeling, one of the Faerie Folk, and also a being not strictly male or female; sometimes neither, sometimes both. The mash up is based on the last two chapters of Anne of the Island, the scenes in which Gilbert Blythe is seriously ill and Anne realises she loves him. This realisation causes Anne, in this version, to reveal to Gilbert that she is both non-human and not a girl, and to use Faerie magic to save Gilbert’s life. Anne’s revelation causes Gilbert a great relief, as he has been keeping a secret also - that he too is queer. The piece has an accompanying research statement and reflection, that reflects on the ways the contributor/author interprets Anne, as a being troubled by gender, and not strictly gender conforming. The much-loved scene from Anne of Green Gables in which Anne realises she is not wanted by the Cuthberts because she is not a boy is inserted into the mash up (as a memory) as this scene is the principal cause for the contributor’s identification with Anne as a gender non-conforming figure who resists gender expectations. Overall, this creative and critical work and reflection queers both Anne as a character and the Anne of the Island novel.Book chapter - work of fiction with a critical reflective essa
Interview with Anne Russell
No full textInterview with Anne Russell, playwright and author of several books on local history, including Wilmington: A Pictoral History
Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes
No full textWe show that the time required to transcribe human genes larger than 800 kb spans more than one complete cell cycle, while their transcription speed equals that of smaller genes. Independently of their expression status, we find the long genes to replicate late. Regions of concomitant transcription and replication in late S phase exhibit DNA break hot spots known as common fragile sites (CFSs). This CFS instability depends on the expression of the underlying long genes. We show that RNA:DNA hybrids (R-loops) form at sites of transcription/replication collisions and that RNase H1 functions to suppress CFS instability. In summary, our results show that, on the longest human genes, collisions of the transcription machinery with a replication fork are inevitable, creating R-loops and consequent CFS formation. Functional replication machinery needs to be involved in the resolution of conflicts between transcription and replication machineries to ensure genomic stability. Copyright © 2011 Elsevier Inc. All rights reserved
A sojourn in Paris 1824-25: sex and sociability in the manuscript writings of Anne Lister (1791-1840)
No full textThis thesis examines the day to day practices that constituted Anne Lister's (1791-1840) sexuality and sociability within the range of her writings, as well as her society. Anne's writings were a detailed account, spanning her lifetime, of her own love and relationships with the 'fairer sex' (Whitbread 1988, 145). Anne's sociality, seen in her correspondence and plain handwritten journal entries, has been explored by Muriel Green in Miss Lister of Shibden Hall and Jill Liddington in Female Fortune and Nature's Domain (Green 1992; Liddington 1998; 2003). As a gentlewoman of adequate means, Anne has garnered some attention from women's historians interested in her agency within an early nineteenth century social and historical context. Anne's sexual identity has been extensively analysed over the past nearly twenty years by lesbian feminists, queer theorists, women's historians and historians of sexuality concerned with the history and development of modern Western female homosexuality and gender. The source for theorising Anne's sexuality has been the edited selections of the crypted journal entries, published by Helena Whitbread in I Know My Own Heart and No Priest but Love (Whitbread 1988; 1992). However, many analyses deal either with the theorisation of Anne's sexuality or her sociality; the theoretical difficulty with reconciling these categories has troubled the analysis of her complex subjectivity. Drawing upon the archival materials, I have used an interdisciplinary feminist approach to analyse the sexual and social processes of Anne's everyday interactions in her writings. Taking the seven month period of the sojourn to Paris in 1824-25, I have focused upon Anne's textual practices within her journal volume and letters during her residence in Paris, her social practices with the other guests at the guesthouse 24 Place Vendome and her sexual practices with her lover, the widow Mrs. Maria Barlow. The journal volumes and correspondence are a valuable historical record of one gentlewoman's engagement with early nineteenth century British culture
Editor's inscription in Valentine Duval : an autobiography of the last century
No full textEditor Anne Manning's gift inscription to author William Stebbing (1832–1926), "To William Stebbing from his affectionate friend the editor Nov. 2, 1860".Manning, Anne, 1807-1879
Dr. Anne Koch
No full textDr. Anne Koch, author of the book It Never Goes Away: Gender Transition at a Mature Age, meets with students Kolby Nelson after a speech at PCOM.https://digitalcommons.pcom.edu/pa_2020_photos/1065/thumbnail.jp
Transcription-replication encounters, consequences and genomic instability
No full textTo ensure accurate duplication of genetic material, the replication fork must overcome numerous natural obstacles on its way, including transcription complexes engaged along the same template. Here we review the various levels of interdependence between transcription and replication processes and how different types of encounters between RNA-and DNA-polymerase complexes may result in clashes of those machineries on the DNA template and thus increase genomic instability. In addition, we summarize strategies evolved in bacteria and eukaryotes to minimize the consequences of collisions, including R-loop formation and topological stresses. © 2013 Nature America, Inc. All rights reserved
Dr. Anne Koch and Kolby Nelson
No full textDr. Anne Koch, author of the book It Never Goes Away: Gender Transition at a Mature Age, meets with student Kolby Nelson after a speech at PCOM.https://digitalcommons.pcom.edu/pa_2020_photos/1064/thumbnail.jp
Prairie Gate Literary Festival Welcomes Author Anne Panning
No full textMorris will welcome author Anne Panning on Friday, November 2, at 7:30 p.m. in the McGinnis Room of Briggs Library. Panning will read from her new novel, Butter
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