1,720,967 research outputs found
Hematopoietic stem cell transplantation (HSCT) as an example of personalized approach in the management of individual disease
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VII Balti hematoloogiakonverents Tartus
Get PDFBalti hematoloogide konverentside traditsioon sai alguse 1998. aastal Tar tus. Esimese konverentsi algataja ja organiseerija oli professor Hele Everaus.
Eesti Arst 2010; 89(7−8):522−52
Use of murine L1210 and P388 lymphocytic leukemia cells in cytotoxic studies of flavonoids
No full textIn studies of antileukemic properties of flavonoids two murine cellular systems (L1210 and P388) are widely used beside the various established human leukemia lines. Differently from conventional clinically used chemotherapeutics, P388 cells reveal somewhat lower susceptibility towards plant polyphenolic agents than L1210 cells. Moreover, based on the cytotoxic analysis of different flavonoids, we provide some novel evidence of Burkitt`s lymphoma as a human equivalent of L1210 mouse model, enabling thus the use of L1210 murine model in development of novel antilymphoma drugs proceeding from natural polyphenols. At that, structurally different flavones can be considered as potential lead compounds; however, the most potent flavonoid described so far in B-cell lymphoma cells is the rotenoid deguelin, certainly requiring further in vitro and in vivo investigation
Nanotechnological approach to improve the bioavailability of dietary flavonoids with chemopreventive and anticancer properties
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Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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