518 research outputs found
Corrigendum to “Transsylvian selective amygdalohippocampectomy in children with hippocampal sclerosis: Seizure, intellectual and memory outcome” [Seizure 21 (2012) 699–705]
No full textTranssylvian selective amygdalohippocampectomy in children with hippocampal sclerosis: Seizure, intellectual and memory outcome
No full textAbstractPurposeThis study investigates the efficacy of transylvian selective amygdalohippocampectomy (TS SAH) in children with medically intractable epilepsy due to unilateral hippocampal sclerosis. Post-surgical seizure control, intellectual and memory outcomes are examined.MethodThis study reports on pre- and post-surgical clinical data from 10 patients who underwent TS SAH between 2002 and 2010 after 24 months follow-up. Pre- and post-operative change in seizure frequency, AED use, intellect and memory are compared.ResultsAt 12 months and 24 months post-surgery, 9/10 (90%) and 7/8 (87.5%) patients respectively, were seizure free (Engel I). No patients were classed as Engel III or IV. No significant improvement or decline at a group level was found on measures of intellect or verbal or visual memory. One hundred per cent improved or remained within 1 SD of their pre-operatives score on verbal and perceptual reasoning learning and reasoning measures. Significant improvement was found post-operatively for both immediate and delayed facial memory.ConclusionOur findings of good post-surgical seizure control and favourable cognitive outcome provides evidence against previous findings that SAH in children may not be effective
Defining indigenous plants: some problematic species from Norfolk Island
No full textDefining indigenous species may at first appear straight forward; most botanical texts provide similar definitions. The consistent requirement of such definitions is the lack of human intervention in the occurrence of the species within the area under consideration. Islands around the world have been invaded by plant species brought to their shores by humans. They are also places where self-introduced species can be continually arriving, as they have done for millennia. Scrutiny of the situation on Norfolk Island (1200 km east of Australia) finds that the distinction between indigenous and introduced taxa is sometimes unclear. There is also inconsistency regarding the acceptance of self-introduced species as indigenous. This paper explores these issues and notes that they are more important than idle botanical curiosity, because control of introduced (weed) species is a major area of activity in managing protected natural areas
Innovating a Career in Games
No full textCelebrate the Kelvin Smith Library\u27s 20 year anniversary at an event around gaming, in honor of guest speaker Phillip Orbanes (CIT\u2770).
Mr. Orbanes, board game designer, author, and founding partner and president of Winning Moves Games in Danvers, Massachusetts will speak. Mr. Orbanes was a Senior Vice President for Research and Development at Parker Brothers until the 1990s, has served as Chief Judge at U.S. National and World Monopoly tournaments, written two books about the board game Monopoly (his book The Monopoly Companion has been printed in three editions) and has written a book about the history of Parker Brothers from the 1880s to the start of the 21st century
Illustrations of the geology of Yorkshire : or a description of the strata and organic remains of the Yorkshire coast : accompanied by a geological map, sections, and plates of the fossil plants and animals
No full textby John Phillip
Las misiones jesuitas de Durango. Antropología. Boletín Oficial del Instituto Nacional de Antropología e Historia: Las misiones en la Nueva España y sus cronistas. Num. 67 Nueva Época (2002) julio-septiembre
No full textDecorme, Gerardo, La obra de los jesuitas mexicanos durante la época colonial (1572-1767), (compendio histórico), Antigua Librería Robredo de José Porrúa e hijos, México, 1941, t. II, p. VII.Hadley, Phillip L., Minería y sociedad en el centro minero de Santa Eulalia, Chihuahua (1709-1750), México, FCE, 1979, p. 20.Lazcano Sahagún, Carlos y Silvia Bouchez Caballero, Fisonomía del Norte, Guía México Desconocido. El Mundo Norte, num. 54, México, Ed. México Desconocido, 1999, p. 9.Messmacher, Miguel, La búsqueda del signo de Dios. Ocupación jesuita de la Baja California, México, FCE, 1997, p. 76.Nolasco, Margarita, Conquista y dominación del noroeste de México: el papel de los jesuitas, México, INAH, 1998, pp. 90-91
Louis Joncas, Phillip McCrum, Claude Perreault : Vanitas
No full textWawzonek provides descriptive analyses of works by three contemporary Canadian artists in an exhibition based on the theme of the moralistic still-life genre known as Vanitas. The author draws attention to how these works differ from traditional Vanitas. Relationships between food/identity and consumerism/selfhood are considered, along with issues of representation, death, desire and disease. List of works. Biographical notes. 4 bibl. ref
The Creative Studio Practice of Contemporary Dance Music Sampling Composers
No full textThis article seeks to investigate some of the considerations that inform and help to determine the creative studio practice of contemporary sampling composers. Collaborative writing and production, specifically the co-opted collaboration implicit in using samples, will be assessed to consider those aspects of the production process which the participants consider to be authorial. These considerations include acts of listening, selecting and editing. In examining these matters this paper places emphasis on how sampling composers actively constrain their options in order to promote a creative relationship with their musical material. Techniques such as, firstly, traditional sample manipulation, secondly, the use of a sample as an initial building block for a composition from which the sample is then removed and, finally, live performance in the studio which is subsequently cut up and treated as a sample, will be discussed. Case studies, in the form of semi-structured interviews with sampling composers, will be drawn upon to assess approaches to and views about these forms of studio compositio
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
No full textINTRODUCTION: The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that alters metabolism by increasing the level of ketone bodies in the blood. KetoCal® (KC) is a nutritionally complete, commercially available 4:1 (fat:carbohydrate+protein) ketogenic formula that is an effective non-pharmacologic treatment for the management of refractory pediatric epilepsy. Diet-induced ketosis causes changes to brain homeostasis that have potential for the treatment of other neurological diseases such as malignant gliomas. METHODS: We used an intracranial bioluminescent mouse model of malignant glioma. Following implantation animals were maintained on standard diet (SD) or KC. The mice received 2×4 Gy of whole brain radiation and tumor growth was followed by in vivo imaging. RESULTS: Animals fed KC had elevated levels of β-hydroxybutyrate (p = 0.0173) and an increased median survival of approximately 5 days relative to animals maintained on SD. KC plus radiation treatment were more than additive, and in 9 of 11 irradiated animals maintained on KC the bioluminescent signal from the tumor cells diminished below the level of detection (p<0.0001). Animals were switched to SD 101 days after implantation and no signs of tumor recurrence were seen for over 200 days. CONCLUSIONS: KC significantly enhances the anti-tumor effect of radiation. This suggests that cellular metabolic alterations induced through KC may be useful as an adjuvant to the current standard of care for the treatment of human malignant gliomas
Functional Characterisation of Alpha-Galactosidase A Mutations as a Basis for a New Classification System in Fabry Disease
No full textThis is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.The study has been supported partially by an unrestricted scientific grant from Shire Human Genetic Therapies (Germany
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