130,537 research outputs found

    Hashimoto Encephalopathy Presenting as Schizophrenia-Like Disorder

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    Objective: Hashimoto encephalopathy (HE) is associated with numerous neuropsychiatric symptoms and responds well to steroid therapy. In the past, only a few cases were reported to present with pure psychiatric syndromes. We describe a case of HE with presenting symptoms like that of schizophrenic patients. Methods: We describe a 73-year-old woman with a history of autoimmune Line thyroiditis. She had psychotic symptoms for 3 years that responded poorly to antipsychotic agents, and she was thus admitted in 2007. Results: The diagnosis of HE was made, although the patient presented neurologic symptoms and signs including abnormal electroencephalography, recent memory impairment, and executive function declination. The psychotic symptoms subsided completely in a few days after high-dose intravenous steroid therapy. Conclusions: The neuropsychiatric manifestation of HE can be similar to typical schizophrenia. Considering the effectiveness of steroid therapy for HE, we suggested HE as an important differential diagnosis for psychotic disorders, particularly for those patients of late onset, with abnormal electroencephalography, history of autoimmune thyroiditis, or poor response to conventional psychiatric treatment, so as to provide prompt and effective treatment for these patients

    Hashimoto-Enzephalopathie – steroid-sensitive Enzephalopathie

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    ZusammenfassungDie Hashimoto-Enzephalopathie ist eine gut behandelbare, steroid-sensitive Enzephalopathie, die sich durch eine Assoziation mit einer Autoimmun-Thyreoiditis (Hashimoto-Thyreoiditis) auszeichnet. Bis jetzt wurden ca. 110 Fallbeschreibungen der Hashimoto-Enzephalopathie in allen Altersgruppen berichtet. Unklarheit besteht über die zugrunde liegenden pathogenetischen Mechanismen. Es können zwei charakteristische Verläufe mit im Vordergrund stehenden neurologischen und psychiatrischen Symptomen unterschieden werden: eine schleichend progrediente Variante und eine akute vaskulitische Form. Trotz unterschiedlicher klinischer Präsentation findet sich generell ein gutes Ansprechen auf eine immunsuppressive Therapie. Bei konsequenter Behandlung ist von einer guten Prognose auszugehen. Im Rahmen des aktuellen Überblicks gehen wir unter anderem auf die zur Zeit diskutierten Ätiologiemodelle, die diagnostischen Standards und die empfohlenen Therapieschemata ein. Differenzialdiagnostische und differenzialtherapeutische Konsequenzen werden diskutiert.</jats:p

    Paralomis jamsteci TAKEDA & HASHIMOTO 1990

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    &lt;i&gt;PARALOMIS JAMSTECI&lt;/i&gt; TAKEDA &amp; HASHIMOTO, 1990 &lt;p&gt; &lt;i&gt;Type locality&lt;/i&gt;: North Pacific Ocean, Okinawa Trough, hydrothermal vents of the Minami-Ensei Knoll; 28&deg;23.4&prime;N, 127&deg;38.4&prime;E; 710 m.&lt;/p&gt; &lt;p&gt; &lt;i&gt;Known range&lt;/i&gt;: Known only from the type locality (above).&lt;/p&gt; &lt;p&gt; &lt;i&gt;Material&lt;/i&gt;: North Pacific Ocean, Okinawa Trough, Minami-Ensei Knoll, 28&deg;23.4&prime;N, 127&deg;38.4&prime;E; 710 m; &lt;i&gt;Shinkai 2000&lt;/i&gt; dive 428; 26 July 1989; NSMT-Cr 10172 [holotype female (ovigerous)], NSMT-Cr 10173 (paratype, 1 male), USNM and MNHN (2 ovigerous females) (Takeda &amp; Hashimoto, 1990; also see Hashimoto &lt;i&gt;et al.&lt;/i&gt;, 1990, 1995; Hashimoto, 1997, in Desbruyeres &amp; Segonzac, 1997).&lt;/p&gt; &lt;p&gt; &lt;i&gt;Remarks&lt;/i&gt;: &lt;i&gt;Paralomis jamsteci&lt;/i&gt; was described as living among beds of mytilid mussels near vent openings (Takeda &amp; Hashimoto, 1990; Hashimoto &lt;i&gt;et al&lt;/i&gt;., 1995). Hashimoto (1997, in Desbruyeres &amp; Segonzac, 1997: 199) described the ecology of the species as &lsquo;crawling around bacterial mats close to hydrothermal vents&rsquo; with vent temperatures reaching 269 &deg;C. Hashimoto &lt;i&gt;et al.&lt;/i&gt; (1995) also mentioned two other unidentified species of &lt;i&gt;Paralomis&lt;/i&gt; living at the Minami-Ensei vent fields (Hashimoto &lt;i&gt;et al.&lt;/i&gt;, 1995; Chevaldonn&eacute; &amp; Olu, 1996). To date the species is known only from that site and from the specimens noted above. See Chevaldonn&eacute; &amp; Olu (1996: 289) for reports of this species feeding on vesicomyid and mytilid bivalves.&lt;/p&gt;Published as part of &lt;i&gt;Martin, Joel W. &amp; Haney, Todd A., 2005, Decapod crustaceans from hydrothermal vents and cold seeps: a review through 2005, pp. 445-522 in Zoological Journal of the Linnean Society 145 (4)&lt;/i&gt; on page 485, DOI: 10.1111/j.1096-3642.2005.00178.x, &lt;a href="http://zenodo.org/record/5434828"&gt;http://zenodo.org/record/5434828&lt;/a&gt

    Aspectos ultrasonográficos da tireóide na doença de hashimoto.

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    Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis, 200

    Aenictus subterraneus Jaitrong & Hashimoto, 2012, sp. nov.

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    &lt;i&gt;Aenictus subterraneus&lt;/i&gt; sp. nov. &lt;p&gt;(Figs 6 A&ndash;E, 7)&lt;/p&gt; &lt;p&gt; &lt;b&gt;Types.&lt;/b&gt; Holotype worker from Malaysia, Borneo, Sabah, Maliau Basin, 8.V.2001, Y. Hashimoto leg. (UMS). Five paratype workers, same data as holotype (MNHA, SKYC, THNHM).&lt;/p&gt; &lt;p&gt; &lt;b&gt;Measurements.&lt;/b&gt; Holotype: TL 2.10 mm; HL 0.55 mm; HW 0.48 mm; SL 0.38 mm; ML 0.78 mm; PL 0.18&ndash;0 mm; CI 86; SI 79.&lt;/p&gt; &lt;p&gt;Paratypes (n = 2): TL 2.10&ndash;2.15 mm; HL 0.55&ndash;0.58 mm; HW 0.48&ndash;0.50 mm; SL 0.38 mm; ML 0.78&ndash;0.80 mm; PL 0.18&ndash;0.19 mm; CI 86&ndash;87; SI 75&ndash;79.&lt;/p&gt; &lt;p&gt; &lt;b&gt;Description of worker&lt;/b&gt; (holotype and paratypes). Head in full-face view clearly longer than broad, with sides convex and posterior margin almost straight or feebly concave; occipital margin bearing a carina. Antennal scape reaching midlength of head; antennal segments II&ndash;X each longer than broad; II almost as long as each of III&ndash;VI; terminal segment clearly longer than broad and almost as long as VII+VIII+IX. Frontal carina short, slightly extending beyond the level of posterior margin of torulus. Masticatory margin of mandible with a large apical tooth followed by a medium-sized subapical tooth, 7&ndash;8 denticles, and a medium-sized basal tooth; basal margin with 4&ndash;5 denticles. Promesonotum in profile convex dorsally and sloping gradually to metanotal groove; metanotal groove distinct; metapleural gland bulla relatively small; distance between propodeal spiracle and metapleural gland bulla clearly longer than spiracular diameter (Fig. 6 D). Propodeum in profile lower than promesonotum with weakly convex dorsal outline; propodeal junction obtusely angulate; declivity of propodeum shallowly concave, with lateral carinae, but not demarcated basally by a transverse carina. Petiole shorter than high, with petiole in profile its dorsal outline convex; subpetiolar process rather developed, with a sharply pointed lamellate appendage directed downward. Postpetiole clearly shorter than petiole, its dorsal outline slightly elevated posteriorly.&lt;/p&gt; &lt;p&gt;Head including mandible and antennal scape smooth and shiny; basal portion of the scape finely sculptured. Entire pronotum smooth and shiny except for its anteriormost portion punctate; mesothorax, metapleuron, and propodium entirely microreticulate; petiole and postpetiole entirely punctate except dorsal faces smooth and shiny. Legs entirely smooth and shiny.&lt;/p&gt; &lt;p&gt;Head and mesosoma dorsally with relatively sparse standing hairs mixed with sparse short hairs over the surface; longest pronotal hair 0.15&ndash;0.18 mm long. Body yellowish-brown, mandible darker than elsewhere; typhlatta spot absent.&lt;/p&gt; &lt;p&gt; &lt;b&gt;Etymology.&lt;/b&gt; The specific name refers to the behaviour of this species that was collected from soil.&lt;/p&gt; &lt;p&gt; &lt;b&gt;Distribution.&lt;/b&gt; Borneo (Sabah) (Fig. 7).&lt;/p&gt; &lt;p&gt; &lt;b&gt;Bionomics.&lt;/b&gt; So far this species is known only from the type locality in a lowland primary forest.&lt;/p&gt; &lt;p&gt; &lt;b&gt;Remarks.&lt;/b&gt; &lt;i&gt;Aenictus subterraneus&lt;/i&gt; is most similar in general appearance to &lt;i&gt;A&lt;/i&gt;. &lt;i&gt;peguensis&lt;/i&gt;. See under &lt;i&gt;A. peguensis&lt;/i&gt; for details.&lt;/p&gt;Published as part of &lt;i&gt;Jaitrong, Weeyawat &amp; Hashimoto, Yoshiaki, 2012, Revision of the Aenictus minutulus species group (Hymenoptera: Formicidae: Aenictinae) from Southeast Asia, pp. 29-44 in Zootaxa 3426 (1)&lt;/i&gt; on page 40, DOI: 10.11646/zootaxa.3426.1.2, &lt;a href="http://zenodo.org/record/214004"&gt;http://zenodo.org/record/214004&lt;/a&gt

    Scheloribates yamaeensis Nakamura & Hashimoto & Nishi & Nakamura & Fujikawa 2015, n. sp.

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    Scheloribates yamaeensisn. sp. [Japanese name: Yamae-shiwadani] (Figs. 6 - 10) Diagnosis — Prodorsum triangular. Rostrum rounded. Lamellae narrower situated laterally, with prolamellae, without cusps and translamella. Sensillus barbed fusiform. Anterior margin of immovable pteromorphae not extending anteriorly beyond level of dorsosejugal scissure; pteromorphae with inward curve. Notogaster elongate with ten pairs of minute setae and four pairs of sacculi; each sacculi diverged. Notogastral integument plicate near posterior margin. Genito-anal setae 4(3, 5)-1(2)-2- 3; genital and aggenital setae variable in number. Adanal setae ad 3 situated in preanal position. Lyrifissures iad aligned along outline of anal aperture in adanal position. Posterial anal locking-pieces remarkable. Diarthric subcapitulum bearing 3 pairs of setae a, m, h. Epimeral setae 3-1-3-3, pedipalpal setae 0-2-1-3-9[1]. All legs heterotridactyl. Solenidiotaxy: I (1-2-2); II (1-1-2); III (1-1-0); IV (0-1-0). Femora II, III and IV with small leg-fin. Solenidia ω 1 and ω 2, famulus, and fastigial seta ft " aligned in a line; setae ft " smooth. Material examined — Holotype (Male) (NSMT- Ac 13034) from litter, humus and soil materials at the chestnut Castanea crenata Sieb. et Zucc. plantation of Yamae Mura in Kumamoto Prefecture on 25 th Oct. 2007, by S. Hashimoto; 24 paratypes (NSMT-Ac, 13035: female): the same data as holotype. The type series with number of NSMT-Ac 13034 & 13035 is deposited in the National Museum of Nature and Science, Tokyo. The remainder of paratypes are deposited in the National Agricultural Research Center for Kyushu Okinawa Region, Kumamoto Prefecture. Etymology — After the name of sampling locality. Measurements and body appearance — Female (n = 13): Body length: 471 (508) 564 µm; width: 300 (345) 400 µm, male (n = 12): Body length: 457 (486) 514 µm; width: 293 (320) 379 µm. Body color light brown. The whole integument without granulation except for exobothridial region. Description of features in common of male and female: Prodorsum — Triangular (Fig. 6A). Rostrum rounded. Rostral setae ro sparsely barbed, inserted at lateral sides, extending in front of the rostrum for a distance equal to about two-third of their length. Lamellar ridges narrower, situated at the lateral sides, with prolamellae but without cusps nor translamella, extending forward from underneath of anterior notogastral margin for a distance equal to almost two-third length of the propodosoma (ca. 125 µm) (Fig. 9A). Lamellar setae le sparsely barbed throughout length, inserted at the end of lamellae (Fig.8B), extending anterior to rostral setae. Interlamellar setae in sparsely spiculate throughout length (Fig. 6C), inserted anterior to the level of bothridia. Bothridial basal part covered by anterior margin of notogaster, opening anteriorly (Fig. 9D). Sensilli ss fusiform, ciliate (Fig. 7A). Exobothridial setae ex smooth, minute. Relative lengths and distances of prodorsal setae: ro: le: in: ss: ex = 1: 1.68:1.68: 1.13: 0.05; (ro-ro): (le-le): (in-in): (ro-le): (le-in) = 1: 1: 1: 0.3: 0.8. Notogaster — Elongate, with broadly rounded anterior margin (Fig. 9C). Anterior margin of immovable pteromorphae not extending anteriorly beyond level of anterior notogastral margin; pteromorphae curved inward (Figs. 6D, 10D). Notogaster bearing 7 to 14 transverse plications near posterior margin (Fig. 9F). A number of light spots arranged peripherally. Dorsophragmatic apophyses hy small. Ten pairs of notogastral setae minute, smooth; c 2 and la on pteromorphae. Sacculi Sa, S1, S2 and S3 diverged (Figs. 8A, 9E, 10C): Sa situated antero-laterally to lm, S1 lateral to lp, S2 posterior to h 3, S3 postero-laterally to h 2, respectively. Lyrifissures ia located parallel to suture between pteromorpha and body posterior to c 2; im aligned obliquely at the antero-laterally to setae lp; ip longitudinally to outline of body between p 1 and p 2. Opisthosomal gland-opening situated posterolaterally to im. Relative distances between notogastral setae in central part of notogaster: (c 2 - c 2): (la-la): (lm-lm): (lp -lp): (h 3 - h 3): (h 2 - h 2): (h 1 - h 1): (p 1 - p 1) = 9: 11: 7: 7: 6: 5: 1: 2. Ventral region — Genital and anal apertures roughly circular in outline (Figs. 6B, 6E, 10A); the latter about 1.5 × as long as the former; distance between them appreciably 1.5 × as long as anal aperture. Genito-anal setae: 4(3, 5)-1(2)-2-3; setae thin, smooth setiform (Fig. 7B); genital g and aggenital ag setae variable in number, but generally (4-4) and (1- 1), respectively. Genital setae g 1 and g 2 remote from g 3 and g 4. Setae ag inserted postero-laterally remote from genital aperture. Adanal setae ad 1 inserted in postanal position; ad 2 postero-laterally; ad 3 preanal. Lyrifissures iad aligned in the paraanal position, between the level of anterior margin of anal aperture and insertion of setae an 2. Posterial anal lockingpieces remarkable (Fig. 10B). Sternal ridge and epimeral border IV indistinct. Custodium extending at the level of trochanter II; discidium small (Fig. 8C). Epimeral setal formula: 3-1-3-3; setae thin, smooth setiform (Fig. 7B), variable in length. Diarthric subcapitulum bearing 3 pairs of setae; setae thin, smooth setiform (Fig. 7C). Mentum without remarkable transverse slit connected with inner pharynx. Chelicera bearing short Trägårdh’s organ (Fig. 7G). Two setae, cha and chb pilose; cha long, chb short. Pedipalpal chaetotaxy: 0-2-1-3-9[1]; tarsus with a short solenidion (ca. 9 µm) not extending forwards from tip of tarsus (Figs. 7F, 9B). Relative lengths of some of the ventral setae: 4c > 4a > g > ad > ag > an. Legs — All tarsi heterotridactylous; claws dorsally serrate. Setal formula of legs including famulus but excluding solenidia: I (1-5-3-4-18), II (1-5- 2-4-16), III (2-3-1-3-14), IV (1-2-2-3-12). Femora of leg II, III and IV bearing small carina (Fig. 7E). Solenidiotaxy I (1-2-2), II (1-1-2), III (1-1-0), IV (0- 1-0). Famulus on tarsus I short, spiniform, situated between ω 2 and fastigial seta ft "; solenidion ω 1 and ω 2 short bacilliform; ω 2 longer than ω 1, inserted posteriorly to ω 1; ω 1, ω 2, famulus and ft " aligned almost in a line (Fig. 7D). Description of different characters between male and female: Female with genital aperture and distance between genital and anal apertures longer than those of male. Remarks — The new species has dorsal aspect similar to those of Scheloribates maoriensis Hammer (1968) and S. gunini Bayartogtokh (2000). However, the plications of posterial margin of notogaster and diverged sacculi are particular characters of the new species.Published as part of Nakamura, Y. - N., Hashimoto, S., Nishi, Y., Nakamura, Y. & Fujikawa, T., 2015, Two new species of Eremellidae and Scheloribatidae (Acari, Oribatida) from the Kuma district of southern Japan, pp. 171-187 in Acarologia 55 (2) on pages 180-186, DOI: 10.1051/acarologia/20152159, http://zenodo.org/record/464012

    Notions of independence related to the free group

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    The central limit problem for algebraic probability spaces associated with the Haagerup states on the free group with countably many generators leads to a new form of statistical independence in which the singleton condition is not satisfied. This circumstance allows us to obtain nonsymmetric distributions from the central limit theorems deduced from this notion of independence. In the particular case of the Haagerup states, the role of the Gaussian law is played by the Ullman distribution. The limit process is explicitly realized on the finite temperature Boltzmannian Fock space. The role of entangled ergodic theorems in the proof of the central limit theorems is discussed. Read More: http://www.worldscientific.com/doi/abs/10.1142/S021902579800013

    RAGE polymorphisms and oxidative stress levels in Hashimoto&apos;s thyroiditis

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    Background: Polymorphisms of the receptor for advanced glycation end products (RAGE) gene have been studied in various autoimmune disorders, but not in Hashimoto&apos;s thyroiditis. Also, increased oxidative stress has been described in patients with Hashimoto&apos;s thyroiditis. The aim of this study was to investigate the possible role of two common RAGE polymorphisms (−429T&gt;C, −374T&gt;A) in Hashimoto&apos;s thyroiditis; in parallel, we studied oxidative stress levels. Materials and methods: A total of 300 consecutive euthyroid women were examined and classified into three groups: Hashimoto&apos;s thyroiditis with treatment (n = 96), Hashimoto&apos;s thyroiditis without treatment (n = 109) and controls (n = 95). For a rough evaluation of oxidative stress, total lipid peroxide levels in serum were measured. The −429T&gt;C AluI and −374T&gt;A MfeI polymorphisms of RAGE were studied in genomic DNA. Results: Significant association of the RAGE system with Hashimoto&apos;s thyroiditis was found only with regard to the prevalence of the −429T&gt;C, but not with −374T&gt;A polymorphism. The levels of oxidative stress were significantly elevated in Hashimoto&apos;s thyroiditis patients under treatment. Further analysis demonstrated that an oxidative stress cut-off value of 590 μmol/L is associated with an increased risk of progression of Hashimoto&apos;s thyroiditis from euthyroidism to hypothyroidism; this risk is further increased in carriers of the RAGE −429T&gt;C polymorphism. Conclusions: Our findings indicate that both examined risk factors may be implicated in the occurrence of Hashimoto&apos;s thyroiditis, but this covers only a fraction of the pathophysiology of the disease. © 2017 Stichting European Society for Clinical Investigation Journal Foundatio
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