79 research outputs found
Short-term and low-dose liraglutide plus metformin decreased body mass index and insulin resistance more than metformin alone in obese women with polycystic ovary syndrome: An open-label randomized controlled study
No full textBackground and objectives: Reduction of weight improves different manifestations of polycystic ovary syndrome (PCOS). This study compared the effects of liraglutide plus metformin versus metformin alone on weight loss and metabolic profiles in obese women with PCOS.
Methods: This open-label randomized controlled clinical trial consecutively recruited newly-diagnosed PCOS patients of reproductive age with obesity (body mass index ≥ 27.5 kg/m2). Following randomization into two equal groups, Group-1 received treatment with metformin 1000 mg daily alone while Group-2 was given metformin 1000 mg plus subcutaneous (SC) liraglutide 1.2 mg daily for 12 weeks. Anthropometric, biochemical and hormonal data and ovarian morphology were assessed at baseline and after 12 weeks. Clinical information and side effects were recorded every four weeks after initiation of the treatment. Glucose, lipids, and all hormones were analyzed by glucose oxidase, precipitation method, and chemiluminescent microparticle immunoassay respectively. Insulin resistance was measured by homeostatic model assessment (HOMA-IR).
Results: Study included 30 participants comprising 15 for each group. Among 15 participants, 5 dropped out from the Group-1 and 1 dropped out from the Group-2. The final analysis was done among 24 participants (Gr-1: 10 and Gr-2: 14). Waist and hip circumference (WC, HC) significantly (p <0.05) decreased in patients treated with only metformin. Menstrual irregularity, BMI (body mass index), HC, systolic blood pressure (BP), 2h-OGTT glucose, fasting insulin, and HOMA-IR significantly (p < 0.05) decreased in the patients of Group-2 after 12 weeks compared to baseline status. Percentage changes of weight, BMI and HOMA-IR improved significantly (p < 0.05) in cases of Group-2 than those in Group-1. Side effects were though numerically higher in the Group-2 patients, but reduced with time.
Conclusions: Addition of liraglutide with metformin was superior to metformin alone for lowering of BMI and insulin resistance among obese PCOS women with acceptable side effects.
IMC J Med Sci. 2024; 18(1):002. DOI: https://doi.org/10.55010/imcjms.18.002
*Correspondence: Muhammad Abul Hasanat, Room# 1524, Level-15, Block-D, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka-1000, Bangladesh. ORCID iD: orcid.org/0000-0001-8151-9792; Email: [email protected]
Abul A‘la Mawdudi’s concept of Hakimiyya and its critical assessment in Islamic legal-political thought
Get PDFThe article analyzes the legal-political aspects of the concept of hakimiyya (“divine
domination”) devised by the Indo-Pakistani theologian Abul A‘la Mawdudi (1903–1979).
The author asserts that the doctrine of hakimiyya is based upon the recognition that Allah
is the sole subject empowered to provide legislation to the Muslim community directly (the
principle of “legal domination”) and indirectly (the principle of “political domination”).The
doctrine of hakimiyya acquires its political shape as the Islamic state (caliphate), wherein the
Islamic community is entrusted with a limited right to legislation by means of agency (wikala).
Special emphasis is laid on examination into the critical appraisal of the hakimiyya doctrinals
in the modern Islamic legal science. The article explores the objections raised against the
hakimiyya theory by the Indo-Pakistani religious scholars, including Abul Hasan Nadwi and
Wahid al-Din Khan, as well as by a number of modern Arabic legal theorists, such as Hasan al-
Hudaybi, Muhammad ‘Imara, Muhammad Sayyid al-‘Ashmawi, Haydar Ibrahim ‘Ali a.o. The
author concludes that the concept of hakimiyya underlies Mawdudi’s doctrine of the sources
of law and serves as the basis for his theory of the Islamic state, as well as for his concept of the
“renewal of faith” through Islamic revolution
Abbasid Gold Coins at the Bangladesh National Museum: A Numismatic and Historical Analysis
Get PDFThis article examines the numismatic and historical significance of eight unpublished Abbasid gold coins housed in the Bangladesh National Museum, focusing on their identification, inscriptional analysis, and historical relevance within the context of early Arab-Bengal trade relations. Discovered in 1996 and 2002 in the Chandpur and Brahmanbaria districts, adjacent to the historically significant archaeological site of Samatata, these coins have received little scholarly attention beyond basic acquisition records. The study employs a historical-numismatic approach, integrating primary sources such as the coins themselves and museum records with relevant secondary literature. It uncovers key numismatic details, including issuing authorities, minting origins, physical characteristics, and inscriptions affirming Islamic monotheism and venerating the Prophet Muhammad (SAW). Through analysis of these inscriptions, the study highlights notable features of Abbasid gold coinage and offers insights into the religious and political dynamics of the period. These coins serve as important material evidence within the broader historical context of early Arab interactions with ancient Bengal, particularly in the sphere of maritime commerce. References in Arab-Persian geographical texts further suggest Bengal's prominence as a commercial hub integrated into early Islamic trade networks. The discovery of these coins substantiates such accounts, illustrating the extent of Arab-Bengal trade relations from the eighth to the tenth centuries. Ultimately, the research situates these coins not merely as monetary instruments, but as artefacts of transregional connectivity and ideological dissemination during the early Islamic period
The role of the accused in English and Islamic criminal justice
Get PDFThis thesis is a comparative study of the role of the accused in the systems of
English and Islamic criminal justice. It seeks to explore the underlying
relationship between the individual and the state through an historical, structural
and contextual analysis of their rules relating to questioning and of confessions.
The analysis of the English system covers the period 1800 to 1984, with
particular reference to developments during the nineteenth century when the
foundations for the modern English state were established. The analysis of the
Islamic system combines traditionally Islamic and modern methods, assessing the
"Islamisation" movement in Malaysia through a religico-structural understanding
of juristic opinion from the four main schools of Sunnite jurisprudence.
The thesis contributes to existing knowledge on a number of levels: first, it
questions and revises the "myth" of "progress" that has dominated observations
of the history of the English criminal justice system; second, it elucidates the
relationship between Islamic law in theory and the law that is applied and
proposed in its name in Muslim states; third, it provides an analytical framework
for drawing comparisons between the underlying values of the systems of English
and Islamic criminal justice.
While acknowledging fundamental differences in terms of outlook and
articulation, the author concludes there are important similarities expressed
through such notions as "suspect" in the English system and "kafir"I"fasiq" in the
Islamic. These act as intermediate constitutional categories to whom the state
owe less protection. But the author notes also that these similarities are not
observed necessarily in the "law" which is implemented or proposed in Muslim
states; exact correspondence depends upon the over-arching political structure
and the institution of Caliphate.
The thesis is divided into six chapters: chapter one sets out the conventional view
of the historical development of English criminal procedure and evidence;
chapter two subjects that to a critique and chapter three offers a revised thesis.
Chapter four, explores methods for interpreting and explaining Islam; chapter
five sets out rules relating to confessions and questioning according to the four
Sunni schools; chapter six puts them into "context" through an examination of
the "Islamisation" process in Malaysia
An analytical study of the theatre of the Syrian playwright Saadallah Wannous, with particular emphasis on the plays written after the 1967 war
Get PDFThis study is an examination of the life and work of
the Syrian dramatist Saadallah Wannous (1941-1997). Wannous's name is virtually unknown in the West; only two academic studies of any significance have appeared in English on this eminent and challenging writer, who was honoured by UNESCO at the end of his life. Even in the Arab world his standing rests largely upon his celebrity as a cultural icon, since professional performances of his plays are rare due to the decline of the theatre in the region, and little attention has been devoted to theatre studies by Arab academics. The two studies in English do not attempt to be comprehensive but focus on particular stages of Wannous's career. This study is, therefore, the first to encompass the full range of Wannous's work. To do so it combines an account of his life which seeks to comprehend the various forces that shaped his thinking with an analysis of his dramatic works. The study concentrates on the plays written in the years following the trauma inflicted on the Arab world by the catastrophe of their
defeat in the Arab-Israeli war of June, 1967. Wannous's career can be divided into three phases: the immature plays of his young manhood which are influenced by European models and generally focus on the social condition of the individual; his middle period - the `theatre of politicisation', when his Marxist politics were the main
factor shaping his drama; and his late works, which are characterised by an extraordinary freedom of thought and expression. The introduction places Wannous in his historical and sociocultural context and provides a brief background explaining the literary and theatrical traditions of the Arab world that influenced his activity as a dramatist. Each phase is then examined in turn and the plays are analysed in accordance with the focus of the study. This means that emphasis is given to the middle period,
but no significant work is neglected. The study aims to trace the trajectory of Wannous's development using a
variety of sources: the plays themselves, Wannous's own journalism and critical writings, interviews with his widow, his friends and colleagues, and numerous
journals, books and articles, some of which contain
important interviews with Wannous that shed light on his thought and ways of working. Use is also made of the
two studies mentioned above. The study shows that Wannous's theatre was influenced by the key political, social and cultural developments of his time, and that he
constantly sought to find forms that would express those transformations in dramatic terms
Al-Dur Al-Farīd Kiai Abul Fadhol Senori, Karya Terbesar Ilmu Kalam Ulama Nusantara
Get PDFThe kalam science is considered an Islamic science that has succeeded in becoming the hallmark of Islam. Even in Orientalist literature it receives special attention, as a special approach too. In al-Dur al-Farīd contains the core themes of kalam science by following the flow of the verses of Al-Laqqani's poetry, the author is also sensitive to modernity and even corresponded with Rashid Ridha. Meanwhile, this can be considered as the greatest work of Indonesian kalam science. This research will provide important information that there are Indonesian ulama whose expertise is on par with world ulama. This study will use Husserl's phenomenological approach, so that we can approach Senori's intentionality and consciousness more clearly
مکاتیبِ مشاہیر بنام رفیق خاور
No full textRafiq Khawar (1908-1990) was a poet, prose-writer and scholar. He edited ‘Maahe-e-Nau’, a literary Urdu magazine published by government of Pakistan’s information department. As editor he would receive letters from renowned writers and poets. This article proffers such letters written to Rafiq Khawar. The letter-writers include Jagan Nath Azad, Ibn-e-Insha, Abul Jalal Nadvi, Ashraf Suboohi, Ahmed Nadeem Qasmi and Intizar Hussain. These letters let the readers see through the persona and glimpses of some writers’ real faces can be seen. Some interesting information can also be extracted from these letters. The author has written footnotes with references and has explained some background where necessary
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