351 research outputs found
Pendampingan Memandikan dan Mengkafani Jenazah pada Siswa SMK Anwarul Maliki Sukorejo Kabupaten Pasuruan
No full textSMK Anwarul Maliki Sukorejo is a Vocational High School based on Anwarul Maliki Sukorejo Islamic boarding school. The pesantren, known as the Anwarul Maliki pesantren, is one of the Islamic boarding schools in Sukorejo Pasuruan. The author takes the service in the form of training assistance for bathing and dressing the corpse which is attended by Anwarul Maliki Vocational School students so that they can become knowledge, understanding, and skills on how to take care of the corpse. The training activities for the washing and washing of the bodies of the Anwarul Maliki Vocational School students went well as planned. Factors that support the smooth running of activities are full support from the school, the cohesiveness of SMK Anwarul Maliki Sukorejo students
Analisis kesalahan berbahasa pada penulisan teks prosedur siswa Kelas VII Pondok Pesantren Ma’had Anwarul Istiqomah Tapanuli Selatan
No full textLatar belakang penelitian ini adalah kesalahan berbahasa pada penulisan teks prosedur siswa kelas VII Pondok Pesantren Ma’had Anwarul Istiqomah Tapanuli Selatan. Faktor yang menyebabkan kesalahan berbahasa yang dilakukan oleh siswa ialah kompetensi dari siswa yang belum memadai atau kurangnya pemahaman dalam sistem linguistic (ilmu bahasa) yang digunakan, baik itu dari pemakaian huruf kapital dan pemakaian tanda baca. Masalah pada penelitian ini adalah bagaimana kemampuan siswa menggunakan huruf kapital dalam penulisan teks prosedur siswa VII Pondok Pesantren Ma’had Anwarul Istiqomah Tapanuli Selatan dan bagaimana kemampuan siswa menggunakan tanda baca dalam penulisan teks prosedur siswa kelas VII Pondok Pesantren Ma’had Anwarul Istiqomah Tapanuli Selatan. Tujuan penelitian ini untuk mengetahui bagaimana kemampuan siswa menggunakan huruf kapital dalam penulisan teks prosedur siswa VII Pondok Pesantren Ma’had Anwarul Istiqomah Tapanuli Selatan dan bagaimana kemampuan siswa menggunakan tanda baca dalam penulisan teks prosedur siswa kelas VII Pondok Pesantren Ma’had Anwarul Istiqomah Tapanuli Selatan. Jenis penelitian yang digunakan yaitu penelitian deskriptif kualitatif. Teknik pengumpulan data yaitu observasi, dokumentasi dan analisis conten. Teknik pengolahan dan analisis data menggunakan reduksi data, penyajian data dan penarikan kesimpulan (verifikasi). Berdasarkan hasil penelitian ditemukan bahwa masih banyak siswa yang melakukan kesalahan pemakaian huruf kapital, adapun jumlah pada temuan pertama terdapat 204 kesalahan, sedangkan temuan kedua terdapat 58 kesalahan. Penurunan kesalahan pemakaian huruf kapital iini dapat dipersentasikan sekitar 25%. Siswa melakukan kesalahan dalam menulis judul teks dan huruf pertama awal kalimat. Adapun hasil yang didapatkan dari kesalahan pemakaian tanda baca pada temuan pertama terdapat 83 kesalahan, sedangkan temuan kedua terdapat 27 kesalahan. Penurunan memakaian tanda baca dapat dipersentasikan sekitar 35%. Siswa mengalami kesalahan dalam penulisan tanda baca titik (.), pemakaian tanda koma (,), pemakaian tanda titik dua (:), pemakaian tanda kurung ((…)). Kesimpulan pada penelitian ini adalah siswa kelas VII pondok Pesantren Ma’had Anwarul Istiqomah Tapanuli Selatan dalam pemakaian huruf kapital dan pemakaian tanda baca sudah mengalami penurunan kesalahan pada penulisan teks prosedu
A multilayered microfluidic blood vessel-like structure
No full textThere is an immense need for tissue engineered blood vessels. However, current tissue engineering approaches still lack the ability to build native blood vessel-like perfusable structures with multi-layered vascular walls. This paper demonstrated a new method to fabricate tri-layer biomimetic blood vessel-like structures on a microfluidic platform using photocrosslinkable gelatin hydrogel. The presented method enables fabrication of physiological blood vessel-like structures with mono-, bi- or tri-layer vascular walls. The diameter of the vessels, the total thickness of the vessel wall and the thickness of each individual layer of the wall were independently controlled. The developed fabrication process is a simple and rapid method, allowing the physical fabrication of the vascular structure in minutes, and the formation of a vascular endothelial cell layer inside the vessels in 3–5 days. The fabricated vascular constructs can potentially be used in numerous applications including drug screening, development of in vitro models for cardiovascular diseases and/or cancer metastasis, and study of vascular biology and mechanobiology.American University of Beirut (startup grant and University Research Board grant)National Council for Scientific Research (Lebanon)National Science Foundation (U.S.) (EFRI-1240443)Immodgel (602694)National Institutes of Health (U.S.) (EB012597, AR057837, DE021468, HL099073, AI105024, AR063745)National Institute of General Medical Sciences (U.S.) ( Award Number P20GM103638-04)King Abdulaziz City for Science and Technology (Grant No. 12-MED3096-3
Reduced Graphene Oxide Incorporated GELMA Hydrogel Promotes Angiogenesis for Wound Healing Applications
No full textNon-healing or slow healing of chronic wounds is among the serious
complications of diabetes. The decrease in blood supply due to lack of angiogenesis
leads to reduced supply of oxygen, nutrients and growth factors resulting in decreased
proliferation and migration of endothelial cells involved in formation of blood vessels.
The absence of vascular network also decreases the number of fibroblasts and
keratinocyte cells in wounded area and therefore results in low collagen deposition in
diabetic wounds. In this study, we report the development of rGO nanoparticles
impregnated GelMa hydrogels where rGO nanoparticles were used for enhancing
angiogenesis and GelMa hydrogel was applied for promoting the growth of tissue
forming cells for wound healing applications. Gelatin methacrylate (GelMA) based
hydrogels loaded with different concentration of rGO nanoparticles were synthesized
by UV crosslinking. Characterization of rGO incorporated GelMA hydrogel retained
excellent porous structure and hydrophilic properties (porosity, degradation, and
swelling). In vitro cytotoxicity studies (Live/Dead and MTT assays), using three
different cell lines, confirmed that the hydrogels are biocompatible. The GelMA
hydrogel containing 2% rGO enhanced the proliferation of the cells (fibroblasts,
Endothelial cells, Keratinocytes) and significant wound healing was observed in wound
healing scratch assay. In vivo using the chick chorioallantoic membrane model showed
that the presence of rGO in the GelMA hydrogel significantly enhanced angiogenesis
Developing Successful Neuroprotective Treatments for TBI: Translational Approaches, Novel Directions, Opportunities and Challenges
No full textThis eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contac
Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine: The Recent Advances
No full textIn tissue engineering and regenerative medicine, the conditions in the immediate vicinity of the cells have a direct effect on cells' behaviour and subsequently on clinical outcomes. Physical, chemical, and biological control of cell microenvironment are of crucial importance for the ability to direct and control cell behaviour in 3-dimensional tissue engineering scaffolds spatially and temporally. In this review, we will focus on the different aspects of cell microenvironment such as surface micro-, nanotopography, extracellular matrix composition and distribution, controlled release of soluble factors, and mechanical stress/strain conditions and how these aspects and their interactions can be used to achieve a higher degree of control over cellular activities. The effect of these parameters on the cellular behaviour within tissue engineering context is discussed and how these parameters are used to develop engineered tissues is elaborated. Also, recent techniques developed for the monitoring of the cell microenvironment in vitro and in vivo are reviewed, together with recent tissue engineering applications where the control of cell microenvironment has been exploited. Cell microenvironment engineering and monitoring are crucial parts of tissue engineering efforts and systems which utilize different components of the cell microenvironment simultaneously can provide more functional engineered tissues in the near future.Version of Recor
Development and characterization of nickel phosphorus based nanocomposite coatings for corrosion protection of steel
No full textCorrosion is the major challenge faced by many industries like marine, automobile, oil and gas industry, etc. Nickel Phosphorus (Ni-P) based coatings are
extensively studied to mitigate corrosion due to their improved corrosion resistance. However, these coatings lack mechanical strength limiting their applications. In the present study, novel Ni-P-X (X=TiC (titanium carbide) and ZrC (zirconium carbide)) were developed through the electrodeposition process. Various amounts of titanium carbide TiC nanoparticles (0, 0.5, 1.0, 1.5, and 2.0 g/L) and ZrC nanoparticles (0, 0.75 and 1.5 g/L) were co electrodeposited in the Ni-P matrix under optimized conditions and then characterized by employing various techniques. It is noticed that the concentration of reinforcing ceramic particles has a significant on the structural, mechanical, tribological, and electrochemical properties of Ni-P nanocomposite coatings. The structural analysis of both types of prepared nanocomposite coatings indicates uniform, compact, and nodular structured coatings without any noticeable defects. Vickers microhardness and nanoindentation results of Ni-P-TiC nanocomposite coatings demonstrate the increase in the hardness with an increasing amount of TiC nanoparticles attaining its terminal value (5.98 GPa) at the concentration Corrosion is the major challenge faced by many industries like marine, automobile, oil and gas industry, etc. Nickel Phosphorus (Ni-P) based coatings are extensively studied to mitigate corrosion due to their improved corrosion resistance. However, these coatings lack mechanical strength limiting their applications. In the present study, novel Ni-P-X (X=TiC (titanium carbide) and ZrC (zirconium carbide)) were developed through the electrodeposition process. Various amounts of titanium carbide TiC nanoparticles (0, 0.5, 1.0, 1.5, and 2.0 g/L) and ZrC nanoparticles (0, 0.75 and 1.5 g/L) were co-electrodeposited in the Ni-P matrix under optimized conditions
and then characterized by employing various techniques. It is noticed that the concentration of reinforcing ceramic particles has a significant on the structural, mechanical, tribological, and electrochemical properties of Ni-P nanocomposite coatings. The structural analysis of both types of prepared nanocomposite coatings indicates uniform, compact, and nodular structured coatings without any noticeable defects. Vickers microhardness and nanoindentation results of Ni-P-TiC nanocomposite coatings demonstrate the increase in the hardness with an increasing amount of TiC nanoparticles attaining its terminal value (5.98 GPa) at the concentratio
Recent Advances in Application of Biosensors in Tissue Engineering
No full textBiosensors research is a fast growing field in which tens of thousands of papers have been published over the years, and the industry is now worth billions of dollars. The biosensor products have found their applications in numerous industries including food and beverages, agricultural, environmental, medical diagnostics, and pharmaceutical industries and many more. Even though numerous biosensors have been developed for detection of proteins, peptides, enzymes, and numerous other biomolecules for diverse applications, their applications in tissue engineering have remained limited. In recent years, there has been a growing interest in application of novel biosensors in cell culture and tissue engineering, for example, real-time detection of small molecules such as glucose, lactose, and H2O2 as well as serum proteins of large molecular size, such as albumin and alpha-fetoprotein, and inflammatory cytokines, such as IFN-g and TNF-α. In this review, we provide an overview of the recent advancements in biosensors for tissue engineering applications.Version of Recor
AN ANGIOGENIC AND ANTIBACTERIAL GELMA MICRONEEDLE ARRAY PATCH FOR DIABETIC WOUND HEALING APPLICATIONS
No full textDiabetic wounds represent a significant healthcare challenge due to their protracted healing processes and susceptibility to infection. Nitric oxide (NO) and oxygen have emerged as promising therapeutic agents for enhancing wound healing in diabetic patients due to their angiogenic and antibacterial properties respectively. In this study, we developed a GelMA (gelatin methacryloyl) microneedle array patch capable of delivering nitric oxide and oxygen to diabetic wounds simultaneously. Nitric oxide was delivered via S-nitrosoglutathione (GSNO) to promote angiogenesis, while calcium peroxide served as an oxygen-releasing agent to exert antibacterial effects. The developed microneedle (MNs) showed sufficient mechanical strength under compression test indicating a potential candidate for transdermal administration of drugs. In addition, the microneedle array patch demonstrated sustained release of nitric oxide and oxygen over a period of 180 minutes. In vitro Live/Dead assay demonstrated no significant cytotoxicity of blank and dual release GelMA MNs in human dermal fibroblast cell lines. Cell proliferation assay using MTT dye showed enhanced proliferation of cells when treated with dual release MNs samples. Finally, scratch assay performed on same cell lines exhibited enhanced migration when treated with dual release samples compared to control and blank samples. Overall, our findings suggest that the Nitric oxide and oxygen-releasing GelMA microneedle array patch holds great promise as an advanced therapeutic approach for diabetic wound healing, offering a synergistic combination of angiogenic and antibacterial effects to expedite the healing process and mitigate complications associated with diabetic wounds
Kepemimpinan KH. Baidhowi Muslich dalam membentuk kultur pesantren study di Pondok Pesantren Anwarul Huda Karang Besuki Malang
No full textINDONESIA:
Seiring perkembangan zaman budaya dalam dunia pendidikan mempunyai peranan penting dalam kehidupan dan perkembangan manusia karena kebudayaan merupakan wahana dimana anak-anak untuk pertama kali dan seterusnya mengalami proses pembelajaran menjadi manusia melalui relasinya dengan sesamanya, alam yang maha tinggi dalam kehidupan sehari-hari. Sehingga pendidikan dalam pesantren sebagai media pengkaderan pemikir-pemikir agama (centre of excellent), mencetak manusia yang berkarakter, membangun pola pikir, sikap, dan perilaku peserta didik agar menjadi pribadi yang positif, berakhlak karimah, berjiwa luhur, dan bertanggung jawab dalam proses mencetak manusia yang berkarakter ini perlulah seorang pemimpin yang memberikan bimbingan, mengarahkan dan mengatur agar mereka mau melakukan hal yang berkaitan dengan suatu tujuan yang diinginkan oleh lembaga pendidikan pesantren.
Berangkat dari inilah penulis kemudian ingin membahasnya dalam Penelitian dan mengambil judul peran KH. Baidhowi Muslikh dalam mengembangkan kultur pondok pesantren (studi kasus di pondok Pesantren Anwarul Huda karang besuki malang ). Tujuan dilakukan penelitan ini adalah untuk mengetahui apa saja budaya yang dikembangkan oleh KH. Baidhowi Muslikh, bagaimana peran KH. Baidhowi Muslikh dalam mengembangkan budaya yang ada di pondok pesantren anwarul huda dan juga untuk mengetahui proses, faktor pendukung dan penghambat dalam pengembangan budaya di pondok pesantren anwarul huda malang.
Pengumpulan datanya dilakukan dengan menggunakan metode observasi, dokumentasi dan wawancara. Sedangkan analisis datanya menggunakan analisis deskriftif yang bertujuan menggambarkan keadaan yang ada dilapangan. Sedangkan jenis penelitian ini adalah penelitian kualitatif deskriptif dengan pendekatan studi kasus.
Hasil dari penelitian yang peneliti dapat bahwa peran KH. Baidhowi Muslikh dalam mengembangkan budaya sangatlah besar. sebagai pengasuh dan pemimpin PP. Anwarul Huda beliau yang mengawal jalannya Proses pengembangan budaya yang dilakukan di PP. Anwarul Huda. Faktor pendukung dari peran kyai dalam membentuk budaya atau kultur dipondok pesantren anwarul huda yaitu : sarana dan prasarana yang menunjang, lingkungan yang kondusif dan peran orang tua yang mendukung dan ikut berperan aktif dalam pengembangan pondok pesantren. Sedangkan yang menjadi penghambatanya antara lain yaitu : dari santri yang tidak disiplin, sistem manajemen yang kurang optimal dan sebagian guru yang tidak mendukung dalam proses pembentukan kultur pondok pesantren.
ENGLISH:
As the times of culture in educational field has an important role in the life and human development because culture is as a vehicle in which the children experience the learning process for the first time and so on to be human through their relationships with each other, the great nature in the everyday life. Therefore a medium of education in a islamic boarding school is cadre of religious thinkers (center of excellence), create human character, build mindset, attitudes, and behaviors of students to become personal positive, good moral, noble-minded, and responsible in the process of printing human character is needed by a leader to give guidance, direct and manage in order they want to do things related to a desired destination by boarding educational institutions.
Departing from this the author then wants to discuss the study and take the title KH. Baidhowi Muslikh’s role in developing a culture of boarding school (in the case study of Anwarul Huda Islamic Boarding Schools Karang Besuki Malang). The purpose of this research is to find out what the culture developed by KH. Baidhowi Muslikh, how the role of KH. Baidhowi Muslikh in developing a culture that is in Anwarul Huda islamic boarding school and also to know the process, motivating and inhibiting factors in the development of culture in the Anwarul Huda islamic boarding school Malang.
Data collection is done by using the method of observation, documentation and interviews. The data analysis using descriptive analysis that aims to describe the existing situation in the field. While this type of research is a descriptive qualitative research with case study approach.
The results of the study in which researcher obtains that KH. Baidhowi Muslikh’s role in developing a culture is enormous. as caregivers and leader of Anwarul Huda islamic boarding school. He is guiding the cultural development process which is conducted in Anwarul Huda islamic boarding school. Factors supporting the role of priest in shaping cultures in Anwarul Huda Islamic boarding schools, namely: infrastructure and facilities support, enabling environment and the role of parents who support and take an active role in the development of islamic boarding school
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