1,727,219 research outputs found

    Direct and comparative visualization techniques for HARDI Data

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    DWI is an MRI imaging technique used to gain information concerning the diffusion process in tissue. Using DTI techniques, a diffusion profile can be constructed for fiber tract analysis. Recently developed HARDI techniques increase the detail to visualization on the process of diffusion. While HARDI reconstruction methods are used to model the underlying diffusion process, the HARDI signal attenuation data can be used for a better understanding of noise in DWI data. This project addresses the direct visualization of HARDI data without any intermediate processing steps between acquisition and visualization. We present new glyph shapes for direct and comparative visualization of HARDI data using the signal attenuation or ADC and a multiple linked views layout. We developed new difference metrics to create a complete comparative visualization pipeline to identify and explore areas of interest. Evaluation of our developed methods by means of a case study, indicates the techniques to be a valued addition. The comparative visualization allows for quick identification of areas of interest. The glyph representation allows for rapid exploration of local diffusion data.Computer GraphicsMediamaticsElectrical Engineering, Mathematics and Computer Scienc

    The Effect of B-value on HARDI Reconstruction

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    The aim of this study was to investigate the effect of the b-value on the high angular resolution diffusion imaging (HARDI) reconstruction and to seek for the appropriate b-value for orientation distribution function (ODF) reconstruction from clinical HARDI data. The full width at half maximum (FWHM) of the ODF and the angular difference of the peaks extracted from ODF were measured to investigate the effect of b-value on the ODF reconstruction. Visual inspection of the ODF was used to evaluate the reconstructions. More detail is provided in "How Does B-Value Affect HARDI Reconstruction using Clinical Diffusion MRI Data?", PLoS ONE (forthcoming)

    Fused DTI/HARDI visualization

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    High angular resolution diffusion imaging (HARDI) is a diffusion weighted MRI technique that overcomes some of the decisive limitations of its predecessor, diffusion tensor imaging (DTI), in the areas of composite nerve fiber structure. Despite its advantages, HARDI raises several issues: complex modeling of the data, non-intuitive and computationally demanding visualization, inability to interactively explore and transform the data, etc. To overcome these drawbacks, we present a novel, multi-field visualization framework that adopts the benefits of both DTI and HARDI. By applying a classification scheme based on HARDI anisotropy measures, the most suitable model per imaging voxel is automatically chosen. This classification allows simplification of the data in areas with single fiber bundle coherence. To accomplish fast and interactive visualization for both HARDI and DTI modalities, we exploit the capabilities of modern GPUs for glyph rendering and adopt DTI fiber tracking in suitable regions. The resulting framework, allows user-friendly data exploration of fused HARDI and DTI data. Many incorporated features like sharpening, normalization, maxima enhancement and different types of color coding of the HARDI glyphs, simplify the data and enhance its features. We provide a qualitative user evaluation that shows the potentials of our visualization tools in several HARDI applications

    Hardi : membangun jembatan hati

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    Coq hardi

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    Variante(s) de titre : Coq Hardi. Je serai...Etat de collection : 1944-1948Appartient à l’ensemble documentaire : Auvergn

    Fast classification scheme for HARDI data simplification

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    High angular resolution diffusion imaging (HARDI) is able to capture the water diffusion pattern in areas of complex intravoxel fiber configurations. However, compared to diffusion tensor imaging (DTI), HARDI adds extra complexity (e.g., high post-processing time and memory costs, nonintuitive visualization). Separating the data into Gaussian and non-Gaussian areas can allow to use complex HARDI models just when it is necessary. We study HARDI anisotropy measures as classification criteria applied to different HARDI models. The chosen measures are fast to calculate and provide interactive data classification. We show that increasing b-value and number of diffusion measurements above clinically accepted settings does not significantly improve the classification power of the measures. Moreover, denoising enables better quality classifications even with low b-values and low sampling schemes. We study the measures quantitatively on an ex-vivo crossing phantom, and qualitatively on real data under different acquisition schemes

    Classification study of DTI and HARDI 1 anisotropy measures for HARDI data 2 simplification

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    High angular resolution diffusion imaging (HARDI) captures the angular diffusion pattern of water molecules more accurately than diffusion tensor imaging (DTI). This is of importance mainly in areas of complex intra-voxel fiber configurations. However, the extra complexity of HARDI models has many disadvantages that make it unattractive for clinical applications. One of the main drawbacks is the long post-processing time for calculating the diffusion models. Also intuitive and fast visualization is not possible, and the memory requirements are far from modest. Separating the data into anisotropic-Gaussian (i.e., modeled by DTI) and non-Gaussian areas can alleviate some of the above mentioned issues, by using complex HARDI models only when necessary. This work presents a study of DTI and HARDI anisotropy measures applied as classification criteria for detecting non- Gaussian diffusion profiles. We quantify the classification power of these measures using a statistical test of receiver operation characteristic (ROC) curves applied on ex-vivo ground truth crossing phantoms. We show that some of the existing DTI and HARDI measures in the literature can be successfully applied for data classification to the diffusion tensor or different HARDI models respectively. The chosen measures provide fast data classification that can enable data simplification.We also show that increasing the b-value and number of diffusion measurements above clinically accepted settings does not significantly improve the classification power of the measures. Moreover, we show that a denoising pre-processing step improves the classification. This denoising enables better quality classifications even with low b-values and low sampling schemes. Finally, the findings of this study are qualitatively illustrated on real diffusion data under different acquisition schemes

    Le Dit du hardi cheval

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    Raynaud Gaston. Le Dit du hardi cheval. In: Romania, tome 32 n°128, 1903. pp. 586-587

    Classification study of DTI and HARDI 1 anisotropy measures for HARDI data 2 simplification

    No full text
    High angular resolution diffusion imaging (HARDI) captures the angular diffusion pattern of water molecules more accurately than diffusion tensor imaging (DTI). This is of importance mainly in areas of complex intra-voxel fiber configurations. However, the extra complexity of HARDI models has many disadvantages that make it unattractive for clinical applications. One of the main drawbacks is the long post-processing time for calculating the diffusion models. Also intuitive and fast visualization is not possible, and the memory requirements are far from modest. Separating the data into anisotropic-Gaussian (i.e., modeled by DTI) and non-Gaussian areas can alleviate some of the above mentioned issues, by using complex HARDI models only when necessary. This work presents a study of DTI and HARDI anisotropy measures applied as classification criteria for detecting non- Gaussian diffusion profiles. We quantify the classification power of these measures using a statistical test of receiver operation characteristic (ROC) curves applied on ex-vivo ground truth crossing phantoms. We show that some of the existing DTI and HARDI measures in the literature can be successfully applied for data classification to the diffusion tensor or different HARDI models respectively. The chosen measures provide fast data classification that can enable data simplification.We also show that increasing the b-value and number of diffusion measurements above clinically accepted settings does not significantly improve the classification power of the measures. Moreover, we show that a denoising pre-processing step improves the classification. This denoising enables better quality classifications even with low b-values and low sampling schemes. Finally, the findings of this study are qualitatively illustrated on real diffusion data under different acquisition schemes
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