1,011 research outputs found
C.difficile infection rate in patients with IBD is falling in line with that of the general population
No full textPoster presentatio
Management of Cognitive Dysfunctions through Ayurveda – Challenges and Opportunities for CAM researchers
No full textIndia’s Long Road: The Search for Prosperity by Vijay Joshi
No full textVijay Joshi‟s India’s Long Road: The Search for Prosperity is an important addition to the list of books on the Indian economy–Jean Dréze and Amartya Sen‟s An Uncertain Glory: India and its Contradictions and Jagdish Bhagwati and Arvind Panagariya‟s Why Growth Matters: How Economic Growth in India Reduced Poverty and the Lessons for Other Developing Countries–written for the interested general reader as well as the specialist. In addition, those readers familiar with the literature assessing and evaluating India‟s economic reforms will remember Joshi as the co-author of India: Macroeconomics and Political Economy, 1964-1991(1994) and India's Economic Reforms, 1991-2001(1996) along with the late I. M. D. Little
P1‐404: EVALUATION OF FREEZE DRIED EXTRACT OF MENTHA PIPERITA IN MANAGEMENT OF COGNITIVE DYSFUNCTIONS IN MICE
No full textP1‐259: Effects of gangetin on memory deficits, neurotransmitter levels and brain oxidativestress in the mouse models of dementia
No full text<i>Zingiber officinale</i>: evaulation of its Nootropic effect in mice
No full textDementia is one of the age-related mental problems, and a characteristic symptom of Alzheimer\'s disease. Nootropic agents and cholinesterase inhibitors like donepezil® are clinically used in situations where there is organic disorder in learning abilities and for improving memory, mood and behavior, but the resulting side-effects associated with these agents have made their utility limited. Ayurveda emphasizes use of herbs, nutraceuticals or life-style changes for controlling age related neurodegenerative disorders. The present study was undertaken to assess the potential of an ayurvedic rasayana (rejuvenator) drug Zingiber officinale Roscoe as a memory enhancer. Elevated plus maze and passive avoidance paradigm were employed to evaluate learning and memory parameters. Z. officinale extract (50 and 100 mg/kg, p.o.) were administered for 8 successive days to both young and aged mice. The dose of 100 mg/kg of Z. officinale extract significantly improved learning and memory in young mice and also reversed the amnesia induced by diazepam (1 mg/kg, i.p.), and scopolamine (0.4 mg/kg, i.p.). Furthermore, it also reversed aging induced amnesia due to natural aging of mice. Z. officinale significantly increased whole brain acetyl cholinesterase inhibition activity. Hence, Z. officinale might prove to be a useful memory restorative agent in the treatment of dementia seen in the elderly. The underlying mechanism of its action may be attributed to its antioxidant and acetyl cholinesterase inhibition property.
Keywords: Zingiber officinale, amnesia, learning, memoryAfrican Journal of Traditional, Complementary and Alternative Medicines Vol. 3(1) 2006: 64-7
Evaluation of nootropic potential of <i style="">Ocimum sanctum </i>Linn. in mice<i style=""></i>
No full text133-136Dementia is one of the age related mental
problems and a characteristic symptom of various neurodegenerative disorders
including Alzheimer’s disease. Certain drugs like diazepam, barbiturates and
alcohol disrupt learning and memory in animals and man. However, a new class of
drugs known as nootropic agents is now used in situations where there is
organic disorder in learning abilities. The present work was undertaken to
assess the potential of O. sanctum
extract as a nootropic and anti-amnesic agent in mice. Aqueous extract of dried
whole plant of O. sanctum ameliorated
the amnesic effect of scopolamine (0.4 mg/kg), diazepam (1 mg/kg) and aging
induced memory deficits in mice. Elevated plus maze and passive avoidance
paradigm served as the exteroceptive behavioral models. O. sanctum extract decreased transfer latency and increased step
down latency, when compared to control (piracetam treated), scopolamine and
aged groups of mice significantly. O.
sanctum preparations could of beneficial in the treatment of cognitive
disorders such as dementia and Alzheimer’s disease
Tuning Transitions in Rotating Rayleigh-Bénard Turbulence
No full textRayleigh-Bénard convection is a canonical system for the investigation of buoyancy-driven natural convection phenomena which abound in nature and technology. Under the influence of rotation and depending on the system parameters, the flow exhibits different regimes with disparate heat transfer characteristics even in the turbulent state. The present study attempts to tune the transitions between these regimes and thus control the heat transfer in practical applications. In particular, we explore the effect of addition of neutrally-buoyant thermally-conducting particles to the fluid. Following an experimental approach, we study the flow structure and heat transfer as functions of particle concentration and system parameters
Herbal drugs and fingerprints : evidence based herbal drugs / Devi Datt Joshi.
No full textIncludes bibliographical references and index.xvi, 252 pages :Evidence based herbal drugs are on hi-acceptance day by day due to health friendly nature compared to synthetic drugs. The active ingredients in herbal drugs are different chemical classes, e.g. alkaloids, coumarins, flavonoids, glycosides, phenols, steroids, terpenes etc., are identified at molecular level using current analytical practices, which are unique characteristic, as finger, so known as fingerprints. The fingerprints are used for assessment of quality consistency and stability by visible observation and comparison of the standardized fingerprint pattern, have scientific potential to decipher the claims made on these drugs for authenticity and reliability of chemical constituents, with total traceability, which starts from the proper identification, season and area of collection, storage, their processing, stability during processing, and rationalizing the combinational in case of polyherbal drugs. These quality oriented documents have ample scientific logics so well accepted globally by regulatory authorities and industries, to determine intentional/ unintentional contamination, adulteration, pollutants, stability, quality, etc. parameters. Based on geo-climatic factors, a same plant species has different pharmacological properties due to different ingredients; such regional and morphological variations are identified by fingerprints, at the time of collection of the medicinal herb. The chromatographic (TLC, HPTLC, HPLC, GC,) and spectral (UV-Vis., FTIR, MNR, MS, LC-MS, GC-MS etc.) techniques have world-wide strong scientific approval as validated methods to generate the fingerprints of different chemical classes of active ingredients of herbal drugs. Presently there is a need for a book having all the fingerprinting techniques for herbal drugs at a place with theory, case studies and art to discover patentable forms. The present book is a mile stone in the subject, to be utilized by Scientists, Medical Doctors, Technicians, Industrialists, Researchers, and Students both in PG and UG level
Nootropic Activity of Calyces of Hibiscus sabdariffa Linn
No full textNootropic acitivity of calyces of Hibiscus sabdariffa Linn. was studied
in mice. Elevated plus maze and passive avoidance paradigm were
employed to evaluate learning and memory parameters. Scopolamine (0.4
mg/kg, i.p.) was used to induce amnesia in mice. The aqueous extracts
of calyces of Hibiscus sabdariffa (HS-100 and 200 mg/kg, p.o.)
significantly attenuated amnestic deficits induced by scopolamine (0.4
mg/kg, i.p.) and natural aging. HS (100 and 200 mg/kg) decreased the
transfer latencies and increased step down latencies significantly in
the aged mice and scopolamine induced amnesic mice as compared with
Piracetam (200 mg/kg, i.p.). To delineate the possible mechanism
through which H. sabdariffa elicits the anti-amnesic effects, we
studied its influence on central cholinergic activity by estimating the
whole brain acetylcholinesterase activity. H. sabdariffa significantly
decreased acetyl cholinesterase activity in mice. The results indicate
that, the aqueous extract of calyces of H. sabdariffa might prove to be
a useful memory restorative agent in the treatment of dementia seen in
elderly. The underlying mechanism of action can be attributed to its
anti acetylcholinesterase property
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