119,018 research outputs found

    Letter to Mr. Hansel Harter from the Assistant Secretary of War with attached correspondence

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    Letter in reply to Mr. Hansel Harter, San Francisco, California, about Nisei Japanese Americans. Attached is a letter from Mr. Harter to Secretary of War Henry L. Stimson expressing faith in the Secretary's leadership

    Family members with mules and carriage outside James Leslie Hansel farmhouse, Erath County

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    Inscription on back of original: ''James Leslie Hansel home near Stephenville, Tex./ L. to r. Nell Hansel, Sue Hansel, and Less Hansel

    Recalcitrant severe hidradenitis suppurativa successfully treated with cyclosporine A.

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    Hidradenitis suppurativa therapy is usually complex and unsatisfactory. Systemic antibiotics, isotretinoin and tumor necrosis factor-alfa are used with relapses following discontinuation. The use of CyA in hidradenitis suppurativa, effective and well tolerated, has rarely been reported in the literature. A 52-year-old male, with an 8-year history of recurrent inflammatory nodular and cystic lesions, discharging sebaceous and seropurulent material associated with sinus and fistula occurrence of the anogenital region, groins, and right axilla, is reported. Several antibiotic therapies, oral isotretinoin, infliximab and etanercept had been ineffective or temporarily effective. The Dermatology Life Quality Index showed a severe impairment of life quality. Oral cyclosporine A was started and after 2 months an improvement of lesions was observed. During the last 2 years cyclosporine A has been well tolerated, with marked reduction in inflammation and suppuration and significant improvement in the quality of life of the patient

    The Oseen-Navier-Stokes flow in the exterior of a rotating obstacle: The non-autonomous case

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    Consider the incompressible Navier-Stokes flow past a rotating obstacle with a general time-dependent angular velocity and a time-dependent outflow condition at infinity – sometimes called an Oseen condition. By a suitable change of coordinates the problem is transformed to an non-autonomous problem with unbounded drift terms on a fixed exterior domain ΩRd\Omega \subset \R^d. It is shown that the solution to the linearized problem is governed by a strongly continuous evolution system U(t,s)U(t,s) on Lσp(Ω)L^p_\sigma(\Omega) for 1<p<1<p<\infty. Moreover, LpLqL^p-L^q smoothing properties and gradient estimates of U(t,s)U(t,s) are obtained. These results are the key ingredients to show local in time existence of mild solutions to the full nonlinear problem for initial value in Lσp(Ω),pdL^p_\sigma(\Omega), p\ge d

    Hansel and Gretel, December 9, 1969

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    Concert program for Hansel and Gretel, December 9, 196

    Hansel and Gretel and the Green Witch by L. North

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    North, Laura.  Hansel and Gretel and the Green Witch. Illus. Chris Jevons. St. Catharines, ON:  Crabtree Publishing, 2015. Print.This book is a “health message” twist on the Hansel and Gretel story.  The children in this story watch television and eat junk food.  They follow a trail of doughnuts into the forest, where they are captured by a witch. Instead of fattening them up, she forces them to do exercise and eat healthy foods, because she only eats healthy kids.   By the time the witch, who sometimes wears sweat pants and carries a megaphone,  thinks Hansel and Gretel are ready to eat, they are fit enough to run away. Children will like the brightly coloured pictures, which the illustrator, Chris Jevons, obviously had fun creating.  They will also be drawn in by Laura North’s completely original take on the story that they already know.  The story is simply told, with easy words for beginning readers. The two puzzles at the end of the book are not essential to the story, but would be a fun way to review the story with children.  This book is recommended for school and public libraries.Highly Recommended:  4 stars out of 4Reviewer:  Sean BorleSean Borle is a University of Alberta undergraduate student who is an advocate for child health and safety

    Allergic contact dermatitis to 3-O-ethyl-L-ascorbic acid: An underrated allergen in cosmetics?

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    3-O-Ethyl-L-ascorbic acid [(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-ethoxy-4-hydroxy-2H-furan-5-one] (CAS no. 86404–04-8), or ethyl ascorbicacid, is an ether derivative of ascorbic acid (vitamin C). 1 The latter ispresent in several foods and dietary supplements. Conversely to thequickly cutaneous degrading of ascorbic acid, the ether group of ethylascorbic acid ensures a greater molecular stability, enhancing its trans-port through skin. Moreover, due to its lipophilic and hydrophilicproperties, ethyl ascorbic acid is used in several cosmetics formula-tions for its whitening, antioxidant, anti-inflammatory, and elasticizingproperties. Despite its frequent use in cosmetics, ethyl ascorbic acidis only rarely reported as a cause of allergic contact dermatitis(ACD

    Atopic Dermatitis and Patient Perspectives: Insights of Bullying at School and Career Discrimination at Work

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    Luca Stingeni,1 Anna Belloni Fortina,2 Ilaria Baiardini,3,4 Katharina Hansel,1 Devis Moretti,5 Filippo Cipriani5 1Dermatology Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy; 2Unit of Dermatology, Department of Medicine - DIMED, University of Padua, Padua, Italy; 3Respiratory Unit for Continuity of Care, IRCCS, Ospedale Policlinico San Martino, Genova, Italy; 4Personalized Medicine Asthma, & Allergy Clinic, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy; 5Sanofi Genzyme, Sanofi S.r.l., Milan, ItalyCorrespondence: Anna Belloni FortinaUnit of Dermatology, Department of Medicine – DIMED, University of Padua, Via Gallucci, 4, Padova, 35128, ItalyEmail [email protected]: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by recurrent eczematous lesions and intense pruritus. AD patients are known to face a considerable disease burden, including physical and emotional limitations. There is still limited knowledge about daily implications in education and occupation. We describe disease social stigmatization by measuring bullying and self-isolation in students and professional discrimination in workers. Overall loss of productivity, either at school and at the workplace, was quantified as the sum of absenteeism (number of days AD sick leave) and presenteeism (number of days with decreased focus and functionality).Methods: An on-line web survey was sent to 3235 random recipients and 401 met the inclusion criteria (self-reporting AD and ≥ 12 yo). The survey domains included daily limitations, QoL, feelings and relationships, together with specific questions about bullying, discrimination and loss of productivity.Results: AD negatively affected QoL in 51.6% of respondents, whereas 68.8% considered AD as a real limit to daily routine. More in detail, 39.3% of students were victims of bullying and 33.9% of workers felt discriminated because of AD. On average, absenteeism in students was for 17.1 days/year (presenteeism: 19.5 days/year), whereas in workers, the estimate was 10.9 days/year (presenteeism: 13.1 days/year). Absenteeism and presenteeism were more pronounced in bullied/discriminated subjects.Conclusion: AD multidimensional implications deeply affect and undermine personal and professional fulfillments. Our results contribute to a better understanding of what living with AD means.Keywords: atopic dermatitis, discrimination, absenteeism, presenteeis
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