1,721,138 research outputs found
Han Gyeol Kim
No full text학위논문(석사)아주대학교 일반대학원 :의학계열,2012. 8I. INTRODUCTION 1
II. MATERIALS AND METHODS 2
A. Study subjects 3
B. Questionnaire 3
C. Genotyping 3
D. Statistical analysis 4
III. RESULTS 5
IV. DISCUSSION 9
V. CONCLUSION 12
REFERENCES 13
국문요약 16MasterBackground: G-protein beta3 subunit (GNB3) C825T polymorphism alters intracellular signal transduction, which may lead to motor or sensory abnormalities of the gastrointestinal tract. The aim of the present study was to evaluate the association of the GNB3 C825T polymorphism with susceptibility to overlap syndrome of functional dyspepsia (FD) and irritable bowel syndrome (IBS) in a Korean population.
Methods: One hundred sixty-seven patients with FD alone, 60 patients with IBS alone, 85 patients with the overlap of FD and IBS, and 434 asymptomatic healthy subjects participated in the study. Genotyping for GNB3 C825T polymorphism was performed using their blood samples.
Results: No association of genotype in subjects with FD alone, IBS alone or overlap phenotype compared to that in controls was detected. The frequency of GNB3 C825T CT and TT genotypes relative to the CC genotype for the phenotypes of FD alone, IBS alone, and the coexistence of FD and IBS did not significantly differ. Comparison of the TT genotype with the CC/CT genotype showed no significant association for each phenotype group.
Conclusions: There is no apparent association of the GNB3 C825T polymorphism with the susceptibility to FD, IBS or the overlap of FD and IBS. A larger-scale study and further investigation on other candidate genes are required
Worte ohne Lieder
No full textPublished„Es gibt kein richtiges Leben im falschen.“ – „Philosophie ist das Allerernsteste, aber so ernst wieder auch nicht.“ – „Aufgabe von Kunst heute ist es, Chaos in die Ordnung zu bringen.“ Solche pointierten Formulierungen haben Theodor W. Adorno in weiten Kreisen bekannt gemacht, und oft werden sie in falscher Vereindeutigung für die komplexe gedankliche Bewegung seiner Texte substituiert. Nichtsdestoweniger leben Adornos Texte von der Spannung, die von seiner mitunter hermetischen, oft aber unvermutet anschaulichen und von polemischem Witz immer wieder durchbrochenen Sprache ausgeht. Das wird auch und gerade in jenem Bereich seines Schreibens deutlich, der auf alle anderen ausgestrahlt hat, und dem Adorno die prägnant doppelsinnige Bezeichnung 'Musikalische Schriften' gab; ähnlich, wie er in späteren Jahren von 'Ästhetischer Theorie' sprach. Dieser Band widmet sich aus interdisziplinärer Perspektive Aspekten der Sprache, des Stils und des Schreibens, insbesondere aber dem Verhältnis von sprachlich artikuliertem Gedanken und musikalischem Denken bei Adorno. Mit Beiträgen von Max Beck und Nicholas Coomann, Lars Fischer, Julia Freund, Wolfgang Fuhrmann, Gabriele Geml, Pola Groß, Christian Grüny, Hans-Joachim Hinrichsen, Han-Gyeol Lie, Cosima Linke, Karsten Mackensen, Claus-Steffen Mahnkopf, Michael Schwarz, Elettra Villani, Boris Voigt und Sophie Zehetmayer
Anisotropic suppression of octahedral breathing distortion with the fully strained BaBiO3/BaCeO3 heterointerface
Get PDFWhile the physiochemical effects of octahedral tilting and rotating distortions have been
studied extensively, octahedral breathing distortion (OBD) at heterointerfaces has rarely
been explored. Here, we investigated OBD in fully strained BaBiO3 (BBO)
epitaxial films by making a new type of oxide heterointerface with non-breathing
BaCeO3 epitaxial films. The integration of first-principles calculations with
experimental observations of optical spectroscopy revealed that the oxygen displacement
modes in BBO became disordered within six unit cells at the heterointerface and the
surface. Controlling OBD in perovskite oxide thin films provides a means to exploit
emerging material properties
Double-Layer Buffer Template to Grow Commensurate Epitaxial BaBiO3 Thin Films
Get PDFWe propose a BaCeO3/BaZrO3 double-layer buffer template, grown on a SrTiO3 substrate, for epitaxial growth of a target oxide film with large lattice constants of over 4.1 . Lattice mismatch from the substrate was mostly accommodated for by a BaZrO3 arbitrating layer. Having an ideal in-plane lattice structure, BaCeO3 served as the main-buffer to grow the target material. We demonstrated commensurate epitaxy of BaBiO3 (BBO,a = 4.371 ) utilizing the new buffer template. Our results can be applied to heteroepitaxy and strain engineering of novel oxide materials of sizable lattice constants. © Author(s) 20161421sciescopu
Controllable Thickness Inhomogeneity and Berry Curvature Engineering of Anomalous Hall Effect in SrRuO3 Ultrathin Films
No full textIn quantum matters hosting electron−electron correlation and spin−orbit coupling, spatial inhomogeneities, arising from competing ground states, can be essential for understanding exotic topological properties. A prominent example is Hall anomalies observed in SrRuO 3
films, which were interpreted in terms of either magnetic skyrmion-induced topological Hall effect or inhomogeneous anomalous Hall effect (AHE).
To clarify this ambiguity, we systematically investigated the evolution of AHE with controllable inhomogeneities in SrRuO 3 film thickness (t SRO ).
By exploiting the step-flow growth of SrRuO 3 films, we induced a microscopically ordered stripe pattern with one-unit-cell differences in t SRO .
The associated spatial distribution of momentum-space Berry curvatures enables a two-channel AHE with hump-like Hall anomalies, which can be continuously engineered according to non-integer t SRO . We further microscopically characterized the stripe-like ferromagnetic domains and two-step magnetic switching behavior in the inhomogeneous SrRuO 3 film. These unique features can be utilized to identify the two-channel AHE model and understand its microscopic origin. © 2020 American Chemical Society11Nsciescopu
Two Mental Models of Non-Professional Design Process for Future Fabrication Interface
Get PDF디지털 패브리케이션은 HCI에 새롭게 떠오르는 화두이다. 일반인이 스스로 자신의 물건을 커스터마이징(Customizing) 할 수 있도록 도와주는 패브리케이션 도구나 인터페이스에 대한 연구는 그간 있었으나 대부분이 미리 정해진 과제, 색깔을 선택하거나 크기를 숫자로 설정하는 데 그쳐왔다. 본 연구는 사용자들이 자신의 이상적인 가구를 어떻게 생각하고 또 묘사하는지를 이해하고자 하며, 그러한 생각이 기존에 가지고 있던 물건과 어떤 관계를 맺는지에 대해서 더 탐구하고자 한다. 이를 위하여 우리는 사용자들이 각자의 집에서 가구에 대해 평소에 어떻게 생각하는지를 알아보았다. 본 연구의 결과는 사용자가 기존의 가구를 평가할 때와 미래의 가구를 묘사할 때의 사고 과정이 차이가 있다는 사실을 시사하며, 향후 미래의 패브리케이션 인터페이스를 제작하는 데 있어 두 가지 사고 과정이 모두 고려되어야 한다는 점을 보여준다
RootBot: root-inspired soft-growing robot for high-curvature directional excavation
No full textBio-inspired robotics garners a significant interest with an aim to improve performance and efficiency in a variety of geotechnical engineering practices. Particularly, the urban environment calls for a new robotic system that can excavate and navigate freely in the subsurface. This study presents a new soft-growing robotic system, RootBot, which exploits inspiration from plant root growth to excavate with steering and directional excavation capabilities through complicated routes and confined spaces. RootBot is designed by incorporating a locomotion mechanism modeled after the plant root growth mechanisms with excavation and discharge systems inspired by tunnel boring machines. A prototype of the RootBot demonstrates several unique features and abilities including directional excavation with a planar motion, a retractive motion, and a sharp steering ability of more than 90 & DEG; rotation with a curvature radius less than twice the width of the excavation head. A series of meter-scale experiments demonstrate that the prototype RootBot can effectively excavate and advance in wet-compacted sand. It can steer at high curvature and even pull back and quarter-turn at any point along a straight path. The RootBot is expected to be useful in various geotechnical and urban engineering practices, including directional ground excavation, navigation through a complicated, curved route to pass by unexpected underground obstacles and soil removal in inaccessible and confined spaces for buried pipe repairs.
Bottleneck-Stationary Compact Model Accelerator With Reduced Requirement on Memory Bandwidth for Edge Applications
No full textState-of-the-art compact models such as MobileNets and EfficientNets are structured using a linear bottleneck and inverted residuals. Hardware architecture using a single dataflow strategy fails to balance the required memory bandwidth with the given computational resources. This work presents a heterogeneous dual-core accelerator that performs a block-wise pipelined process as a unit using a bottleneck-stationary (BS) dataflow. The BS greatly relieves the requirement on DRAM bandwidth and on-chip SRAM capacity. A look-behind-only attention is also proposed as a co-optimized algorithm. Compared to the state-of-the-art hardware scheme, the proposed accelerator demonstrates a reduction of 1.8-2.9 in latency and 2.2-3 in energy consumption, respectively.For verification, the accelerator with a 16-bit integer precision was implemented using 28nm CMOS process. Measurements show energy efficiencies of 0.5-to-3.75 TOPS/W in a supply voltage range of 0.55-to-1.15V. IEEE11Nsciescopu
Laboratory evidences on accelerated fatigue failure in brittle granitic rock by coupled thermal and mechanical cyclic loading: Acoustic emission monitoring and implication to underground hydrogen storage
No full textIn underground hydrogen storage (UHS), injecting and recovering hydrogen in response to fluctuating energy supply and demand introduces unique challenges associated with thermal and mechanical cyclic loadings, leading to potential fatigue failure of the host rock. However, the effect of thermal cycles on the fatigue of crystalline rocks remains poorly understood. This study presents laboratory evidences on accelerated fatigue failure in brittle granitic rock by coupled thermal and mechanical cyclic loading, using acoustic emission (AE) monitoring. A series of uniaxial compression tests were conducted to characterize fatigue damage evolution under cyclic loading at a constant temperature of similar to 8 degrees C (CYC) and cyclic loading with temperature variations of similar to 8-80 degrees C (CYC-T). The results show that thermal cycles accelerate fatigue damage, with CYC-T specimens failing after an average of 3.3 cycles compared to 5.8 cycles for CYC specimens. This accelerated fatigue damage was corroborated by their systematically different increasing patterns of cumulative AE counts, which indicates that thermal cycles facilitate coalescence of fatigue microcracks leading to more abrupt and catastrophic failure. The shift in AE peak frequencies reveals the formation of a new group of cracks that differ in size and location, highlighting the complex interactions between thermally induced and mechanically induced microcracks. Young's modulus exhibits only a slight decrease while Poisson's ratio increases markedly under both loading conditions, indicating significant dilative behavior and crack propagation. The findings in this study underscore the necessity of incorporating thermal stress management strategies in the design and operation of UHS systems for long-term stability and operational sustainability.
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