1,720,969 research outputs found
Complete NMR assignment and conformational analysis of 17-α-ethinylestradiol by using RDCs obtained in grafted graphene oxide
No full textThe 1 H and 13 C NMR spectra of 17-α-ethinylestradiol (EE2), a well-known contraceptive, including diastereotopic methylene groups, were fully assigned with the help of residual dipolar couplings (RDC) measured in the recently developed grafted graphene oxide orienting medium. RDC analysis, which included all 1 DCH couplings and the long-range 2 DCH1 H-C≡13 C coupling, also pointed to the presence of a minor conformation arising from pseudo-rotation of the steroid B ring. Saturation-transfer difference (STD) measurements revealed that the most likely interaction between EE2 and orienting medium occurred on the C and D ring
Isolation, spectral characterization, molecular docking, and cytotoxic activity of alkaloids from Erythroxylum pungens O. E. Shulz
No full textPereira, Gabrielle Macedo, Moreira, Letícia Gondim Lambert, Neto, Themístocles da Silva Negreiros, Almeida, Wamberto Alristenio Moreira de, Almeida-Lima, Jailma, Rocha, Hugo Alexandre Oliveira, Barbosa, Euzébio Guimarães, Zuanazzi, José Angelo S., Almeida, Mauro Vieira de, Grazul, Richard Michael, Navarro-Vázquez, Armando, Hallwass, Fernando, Ferreira, Leandro de Santis, Fernandes-Pedrosa, Matheus de Freitas, Giordani, Raquel Brandt (2018): Isolation, spectral characterization, molecular docking, and cytotoxic activity of alkaloids from Erythroxylum pungens O. E. Shulz. Phytochemistry 155: 12-18, DOI: 10.1016/j.phytochem.2018.07.003, URL: http://dx.doi.org/10.1016/j.phytochem.2018.07.00
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
RMN de natftalenos 1,4- e 1,4,8 - substituidos: estudo da interdependencia do deslocamento quimico e da constante de acoplamento com as propriedades do substituinte
Full text linkDissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas.Admite-se, de longa data, que a escovação dentária constitui um dos procedimentos mais utilizados e o mais eficaz no sentido de manter uma boa higiene bucal. Contudo, através de observações e estudos realizados sabe-se também que um grande número de pessoas não consegue atingir tal objetivo, devendo-se atribuir tal fato a uma série de fatores dentre os quais cita-se a freqüêcia de escovacão diária. Devido a existência de registros conflitantes entre freqüência de escovação e estado de higiene bucal, visamos no presente trabalho correlacionar a freqüência da escovação diária com o grau de remoção da placa bacteriana. Esta experiência foi realizada ccm 42 alunos do Curso de Graduação em Odontologia da Universidade Bederal de Santa Catarina de ambos os sexos e com idade compreendida entre 20 e 25 anos de idade. Na avaliação do grau de higriene devida a freqüência da escovação, utilizamos o índice de GREENE & VERMILLION. Da análise dos dados obtidos parece-nos lícito afirmar: 1 - Existe uma diferença significante para a média de índice de placa dentária de indivíduos que escovaram os dentes 1 vez ao dia quando comparados com outros que escovaram seus dentes 2 ou 3 vezes ao dia; entretanto, no que diz respeito a média do índice de placa dentária remanescente, não existe diferença para os que escovaram seus dentes 2 ou 3 vezes diárias
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