5,275 research outputs found
The Cassandras in Exile: A Study of the Diasporic Sensibility in the Poetry of Meena Alexander, Sujata Bhatt, Chitra Banerjee Divakaruni, Moniza Alvi and Jean Arasanayagam
No full textNot availabl
Proline C−H Bonds as Loci for Proline Assembly via C−H/O Interactions
No full textThis is the peer reviewed version of the following article: Daniecki, N..J., Bhatt, M..R., Yap, G..P.A. and Zondlo, N..J. (2022), Proline C–H bonds as loci for proline assembly via C–H/O interactions. ChemBioChem. Accepted Author Manuscript. https://doi.org/10.1002/cbic.202200409, which has been published in final form at https://doi.org/10.1002/cbic.202200409. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. This article will be embargoed until 09/21/2023.Proline residues within proteins lack a traditional hydrogen bond donor. However, the hydrogens of proline are all sterically accessible, with polarized C–H bonds that can be sites for molecular recognition. C–H/O interactions, between proline C–H bonds and oxygen lone pairs, have been previously identified as modes of recognition in proteins. A series of proline derivatives was synthesized, including 4R-hydroxyproline nitrobenzoate methyl ester, acylated on the proline nitrogen with bromoacetyl and glycolyl groups, and Boc-4S-(4-iodophenyl)hydroxyproline methyl amide. All three derivatives exhibited multiple close intermolecular C–H/O interactions in the crystallographic state, with H•••O distances as close as 2.3 Å. These observed distances are well below the 2.72 Å sum of the van der Waals radii of H and O. We further analyzed the role of C–H/O interactions in all previously crystallized derivatives of these amino acids, and found that all 26 structures exhibited close intermolecular C–H/O interactions. Finally, we analyzed all proline residues in the Cambridge Structural Database. The majority of these structures exhibited intermolecular C–H/O interactions at proline C–H bonds, suggesting that C–H/O interactions are an inherent and important mode for recognition of and higher-order assembly at proline residues. Due to steric accessibility and multiple polarized C–H bonds, proline residues are uniquely positioned as sites for binding and recognition via C–H/O interactions.We thank NSF (CHE-2004110 and BIO-1616490) for funding.Instrumentation support was provided by NIH (GM110758, S10-OD026896A) and NSF (CHE-1229234)
Topology-aware distributed graph processing for tightly-coupled clusters
No full textCloud applications have burgeoned over the last few years, but they are typically written for loosely-coupled clusters such as datacenters. In this thesis we investigate how one can run cloud applications in tightly-coupled clusters and network topologies, namely super-computers. Specifically, we look at a class of distributed machine learning systems called distributed graph processing systems, and run them on NCSA Blue Waters. Partitioning the graph is key to achieving performance in distributed graph processing systems. We present new topology-aware partitioning techniques that better exploit the structure of the network topologies in supercomputers. Compared to existing work, our new Restricted Oblivious and Grid Centroid partitioning approaches produce 25-33% improvement in makespan, along with a sizable reduction in network traffic. We also discuss optimizations such as smart network buffers that further amplify the improvement. To help operators select the best graph partitioning technique, we culminate our experimental results into a decision tree.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2020-05-01The student, Mayank Bhatt, accepted the attached license on 2018-04-23 at 17:13.The student, Mayank Bhatt, submitted this Thesis for approval on 2018-04-23 at 17:20.This Thesis was approved for publication on 2018-04-24 at 15:21.DSpace SAF Submission Ingestion Package generated from Vireo submission #12435 on 2018-08-31 at 17:21:19Made available in DSpace on 2018-09-04T20:36:52Z (GMT). No. of bitstreams: 2
BHATT-THESIS-2018.pdf: 1415794 bytes, checksum: e08311d8168967b2e47baf1ef67f7fdc (MD5)
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Previous issue date: 2018-04-24Embargo set by: Seth Robbins for item 107297
Lift date: 2020-09-04T20:37:00Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 107297
Lift date: 2020-09-04T20:42:08Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 107297 on 2020-09-05T09:15:32Z
Exogenous pulmonary surfactant in COVID-19 ARDS. The similarities to neonatal RDS suggest a new scenario for an 'old' strategy
No full textAcute respiratory distress syndrome (ARDS) related to SARS-CoV-2 infection has some unusual characteristics that differentiate it from the pathophysiology described in the more 'typical' ARDS. Among multiple hypotheses, a close similarity has been suggested between COVID-19 ARDS and neonatal respiratory distress syndrome (RDS). With this opinion paper, we investigated the pathophysiological similarities between infant respiratory diseases (RDS and direct neonatal ARDS (NARDS)) and COVID-19 in adults. We also analysed, for the first time, similarities in the response to exogenous surfactant administration in terms of improved static compliance in RDS and direct NARDS, and adult COVID-19 ARDS. In conclusion, we believe that if the pathological processes are similar both from the pathophysiological point of view and from the response in respiratory mechanics to a recruitment treatment such as surfactant, perhaps the latter could be considered a plausible option and lead to recruitment in clinical trials currently ongoing on patients with COVID-19
Erratum: Hybrid group recommendation using modified termite colony algorithm: A context towards big data (Journal of Physical Chemistry (2018) 17:2 (1850019) DOI: 10.1142/S0219649218500193)
No full textWe would like to make the following correction to this article. The third author a±liation should be read as follows: Chintan Bhatt U. & P. U. Patel Department of Computer Engineering Charotar University of Science and Technology Changa, Gujarat 388421, India [email protected]
The Dementia Dilemma in India: Addressing the Care Challenges with a Layered Interventional Model (LIM)
No full textThis project presents a literature review focused on the growing public health challenge of dementia in India. With the aging population increasing rapidly, the burden of dementia-related care is expected to intensify in coming decades. The review examines existing research, health system gaps, and sociocultural challenges related to dementia care across urban and rural settings.
The core contribution of this work is a proposed layered interventional model designed to strengthen dementia care through a combination of community-based services, caregiver support, primary health integration, and policy-level reforms.
The goal of this project is to:
Highlight critical gaps in dementia care infrastructure and awareness
Synthesize research on existing care models and interventions
Propose a strategic, layered approach to improve dementia outcomes in India.
Author: Jessica Bhatt
Affiliation: Independent Researcher
Date: May 2025
Tags: Dementia, Care Pathway, India, Challenges, Potential Solutions, Geriatric Care, Health Systems, Literature Revie
A Scientometric Exploration of Global Publications of Yoga Research from 2002-2021
No full textThe paper aims to provide an in-depth evaluation of the research output of Yoga for a period of 20 years, from 2002-2021. A total of 3498 documents retrieved from the Web of Science(WoS) database are considered for this analysis. The research finds that Cramer, H. was a most prolific author in Yoga scientific research with the highest 79 publications and top 2980 global citations. The most productive country is the USA, with 23967 publications, followed by India (5822) and Australia (2258). There was a significant increase in publications during the period of study. Most articles were published in the Journal of Alternative and Complementary Medicine. The highest number of Yoga research papers were contributed by two Indian institutions: All India Institute of Medical Sciences and the National Institute of Mental Health and Neuro-Sciences. Cramer H’ published the highest number of papers. The present study will be helpful for other researchers for further studies on Yoga research and policymakers for funding decisions and strategies
A short glossary of inclusive language
No full text© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Craig, S. E., & Bhatt, E. A short glossary of inclusive language. Oceanography, 34(2), (2021), https://doi.org/10.5670/oceanog.2021.207.Words matter—that old adage that many of us may have heard as children,
Sticks and stones may break my bones,
but words will never hurt me,
is a harmful fallacy. In reality, the language we use has tremendous power to alienate, exclude, deride, humiliate, and wound
Not Available
No full textBook chapter published in book entitled as compilation of winter School on seed production technology and quality control standards in fodder crops held at IGFRI, Jhansi during February 26 to March 18, 2009, (eds. R. K. Bhatt et. al.)Not AvailableNot Availabl
Mapping and Visualizing Research of COVID-19 with Immunology: A Bibliometric Study
No full textThis paper aims to demonstrate the World’s scientific contribution to COVID-19 and Immunology research for 2020–2022 and the emerging research pattern using various bibliometric parameters. The research publications were
retrieved from the SCOPUS database and analyzed using MS Excel, R Studio, and VOS Viewer software. The VOS Viewer software is mainly used for networking and visualization to understand the research pattern better. A total of 2877 documents were retrieved from SCOPUS using the search topic
COVID-19 and Immunology. The research found that DIAO B was a prolific author in COVID-19 and Immunology research, with 1247 publications. The most productive countries and institutions in this field were the USA (555 publications) and Huazhong university of science and technology (409
publications). The five hot author keywords are COVID-19, Sars-cov-2, Vaccine, Coronavirus and Antibody. The present study provides various networking map of research publications regarding the immune response
during COVID-19 infection. The results benefit researchers and practitioners in India and worldwide for understanding the pattern of research on COVID19 and identifying the potential immune response against SARS-CoV-
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