40 research outputs found
Study of Pakistan pilot project farmer-leaders to Nepal
No full textFarmer participation / Irrigation management / Farmer managed irrigation systems / Irrigated farming / Sustainable agriculture / Institution building / Pakistan
Pseudo-neoplastic Lesions of Prostate and the Diagnostic Deception
No full textIntroduction: Many pseudo-neoplastic lesions of the prostate gland are recognized. Histologically these lesions mimic the adenocarcinoma of prostate. Pseudo-neoplastic lesions comprise of different glandular and non-glandular or solid patterns. Largely emphasized on the epithelial origin but some stromal and solid lesions are also important. In developing countries, the routine Hematoxylin and eosin (H&E) stain is most commonly used to stain the histological tissue sections. The other stains and molecular studies are not frequently used. The pseudoneoplastic lesions are so obscure and deceptive that sometimes it become very difficult to recognize. The diagnostic facilities both in government and private sector should have at least the facility of immunohistochemical staging to avoid misinterpretations.
Methodology: This retrospective study performed at Muhammad Medical College Mirpurkhas Sindh. 192 specimens of radical prostatectomy (RP) and transurethral resection of the prostate (TURP) received between January 2015 to December 2017 were retrieved for review. All retrieved blocks processed as per standard histopathological techniques. Fresh tissue sections taken and stained with H&E.
Results: All tissue sections reviewed to observe the glandular patterns, their architectural morphology, cytological changes and inflammatory process. The lesions were distinguished on epithelial origin and glandular patterns. Cases of benign prostatic hyperplasia were 169 (88 %), adenosis 06 (3.12 %), reactive hyperplasia 06 (3.12 %), Post atrophic hyperplasia 05 (2.6 %), benign stromal proliferation 02 (1 %) and prostate carcinoma 04 (2%).
Conclusion: Many pseudoneoplastic lesions of the prostate are the mimicker of adenocarcinoma. On H&E stains it sometimes become difficult to differentiate the lesions. The histomorphological diagnosis of these lesions should be facilitated at least by immunohistochemical stains at diagnostic tcenters.t
Keywords: Immunohistochemistry, Transurethral resection of prostate (TURP), Radical prostatectomy (RP). Hematoxylin and Eosin (H&E)
Hydraulic simulations to evaluate and predict design and operation of the Chashma Right Bank Canal
No full textIrrigation systems / Irrigation canals / Flow control / Velocity / Canal regulation techniques / Hydraulics / Simulation models / Design / Operations / Crop-based irrigation / Distributary canals / Water delivery / Policy / Protective irrigation / Water allocation / Water requirements / Sedimentation / Water distribution / Equity / Water conveyance / Pakistan / Chashma Right Bank Canal
The Role of Muhammad Umar Memon in Fictional Translations
No full textThe history of fiction translation in Urdu Language is not veryold and one of the able translator we see in this history isMUHAMMAD UMAR MEMON. The element of creativity canbe seen prominently in its translations. He adapted the works ofArabic, French, English, Czech writers into Urdu style such away that due to the rare use of similes, the meaning was freedfrom the confines of the text even for the Urdu Readers. Themain merit of MemonLs translations is that while having acreative element, do not depart form the source text so that thestory reach the target in that style the author intended. Thepleasant style in which the complicated plot story is welladopted to the target language is a proof of its trustworthiness
Analysis of Helicobacter pylori gastritis according to Sydney classification.
No full textIntroduction: Since H. Pylori has been isolated in stomach and duodenum, there were individual methodologies to explain the grading according to colonization and density of microorganism. In 1990 Sydney system of classification was proposed at the 9th world congress of gastroenterology in Sydney Australia, based on topo-graphical, morphological and etiological findings. This classification revised in 1994 and updated by experts in Houston Texas. H. Pylori is major cause of chronic gastri-tis results in gastric and peptic ulcer. It also causes MALT lymphoma and malignan-cy. For histopathological examination four specimens, two from antrum and two from corpus are recommended.Objective: To evaluate the Sydney system of classification and grading for H. Pylori in local population.Methodology: 287 cases of biopsies received at the department of pathology Mu-hammad Medical College, Mirpurkhas Sindh Pakistan, during the period of January 2017 to December 2018 were revised. Sections stained with Hematoxylin and Eosin; Alcian blue and periodic acid Schiff to define H. Pylori and associated pathological changes. The microscopical findings classified according to upgraded Sydney pattern.Results: Out of 287 cases of gastric biopsies 23 (8.0%) were positive for H. Pylori. chronic inflammation present in 168 (58.5%). Neutrophilic activity found in 58 (18.1%). Atrophy without metaplasia observed in 31 (10.8%). Intestinal metaplasia present in 1 (0.3%) cases.Conclusion: Sydney system of grading is best to evaluate chronic gastritis and relia-ble indicator of H. Pylori microorganism.
Keywords: Chronic gastritis, Gastric carcinoma. H. Pylori
Assessment of Fertility-Related Quality of Life and its Associated Factors among Females of Reproductive Age at a Secondary Care Public Hospital, Hub Chowki, District Lasbela, Balochistan
No full textNot Availabl
Diagnosis of hepatoma using grayscale and Doppler ultrasound in patients with chronic liver disease
No full textWasim A Memon, Zishan Haider, Mirza Amanullah Beg, Muhammad Idris, Tanveer-ul-Haq, Waseem Akhtar, Sidra IdrisRadiology Department, Aga Khan University Hospital, Karachi, Pakistan Every author contributed equally to the workObjective: To determine the diagnostic accuracy of liver ultrasound for the detection of hepatoma in chronic liver disease (CLD) patients by either taking histopathology or serum α-fetoprotein levels or a biphasic computed tomography (CT) scan (whichever is available) as the gold standard.Study design: Cross-sectional.Place and duration of study: Radiology Department, The Aga Khan University Hospital, Karachi, Pakistan, from January 2007 to January 2010.Methods: A total of 239 patients (156 males and 83 females) with clinical suspicion or surveillance of hepatoma in CLD referred to the radiology department for ultrasound evaluation followed by either liver biopsy and histopathology or serum α-fetoprotein level or biphasic CT scan.Results: The sensitivity of ultrasound for hepatoma detection in CLD was 65%, specificity was 85%, and accuracy was 70%, and positive predictive value and negative predictive value were 92% and 45%, respectively.Conclusion: Ultrasound is a relatively quick, safe, reasonably accurate, and noninvasive imaging modality for the detection of hepatoma in CLD and can be complemented with clinical assessment of screening high-risk patients.Keywords: hepatoma, ultrasound, radiology, chronic liver diseas
A Conceptual Framework of the Individual Antecedents to Knowledge Sharing- With Empirical Evidence and Managerial Implications
No full textPurpose: The increasing importance of knowledge sharing, almost all successful firms deem knowledge sharing and knowledge management as one of the central and strategically most important organizational concerns and allocate huge budgets to the effective management and transfer of knowledge. However, despite some very thoughtful measures taken by organizations, most of the firms fail to reap the fruits of knowledge sharing due to being ignorant regarding the individual, organizational and contextual factors that facilitate or impede the process of organizational knowledge sharing.
Design/Methodology/Approach: This research is based on the PhD research dissertation of the author and it was conducted through qualitative content analysis of research articles on the subject matter.
Findings: In this paper, in the light of the existing literature and available empirical evidence, a conceptual framework of individual antecedents (determinants) of knowledge sharing is presented. Based on the findings of this research, interpersonal trust, intension to share, self-efficacy, feeling of self-worth, organizational commitment, reciprocity, a passion to help others are the most important individual antecedents to knowledge sharing.
Implications/Originality/Value: This research offers some key thoughts and implication for the managers and practitioners, to know the individual factors that facilitate the process of KS within organizations. The author has also suggested some valuable recommendations at the end, for the effective management of knowledge sharing in organizations. The paper also provides a meaningful and productive ground for conducting qualitative or quantitative research but can also help researchers in the designing of instruments for conducting research on the topic of individual antecedents to knowledge sharing (KS)
شاعری بطورعملِ تاریخ
No full textThis article titled “Poetry as an Act of History” is an Urdu translation of María Rosa Menocal’s essay, along with the translator’s notes. The author studies how the influence of the Andalusian culture and the forgotten past of three great civilizations associated with it sill echoes in literary works, especially poetry. The article begins with Andalusian references in Cervantes’ Don Quixote and moves on to trace these in poems of Mahmoud Darwish and Lorca’s translations of Andalusian poetry. The author argues that historicity is revealed more in literature than in history itself
