48 research outputs found
Determinants of Breast and Cervical Cancer Screening Uptake Among Women in Turkey
No full textThe aim of the study was to assess the influence of sociodemographic characteristics on breast and cervical cancer screening among women 30 years and older in Turkey. We used data from the National Chronic Diseases and Risk Factors Survey conducted by the Ministry of Health in 2011. Multivariate logistic regression analysis was used to assess the association of sociodemographic factors, lifestyle variables, and cancer screening. Overall, 22.0% of women ever had a Pap smear test for cervical cancer screening and 19.0% ever had a mammography for breast cancer screening(n = 6846). Individuals with a university degree, social security, doing moderate physical activity, and consuming 5 portions of fruit or vegetable/day were more likely to receive Pap smear test and mammography. Residing in the eastern region and living in rural area was associated with lower likelihood of receiving both types of screening
Determinants of prevalence, awareness, treatment and control of high LDL-C in Turkey
No full textObjective: High blood cholesterol is one of the main modifiable risk factors for cardiovascular diseases (CVDs). The aim of the study is to determine the factors associated with the prevalence, awareness, treatment, and control of high low-density lipoprotein-cholesterol (LDL-C) among adults aged >= 20 years in Turkey. Methods: We used data from Chronic Diseases and Risk Factors Survey conducted in 2011-2012. The presence of high LDL-C, lipid-lowering treatment eligibility, and achievement of target LDL-C were defined according to the third Adult Treatment Panel guidelines on treatment of high cholesterol. Multivariate logistic regression analyses were performed to determine the associations between participant characteristics and high LDL-C prevalence, awareness, treatment, and control. Results: Framingham risk score categorization was performed for 13121 individuals aged >= 20 years. Approximately, 28% of the participants presented with high LDL-C. Among those with high LDL-C, 55.8% were aware of their situation; among those aware of high LDL-C, 46.9% were receiving lipid-lowering medication, and 50.6% of individuals who were receiving treatment achieved target LDL-C levels on the basis of their coronary heart disease (CHD) risk. Control of high LDL-C was negatively associated with the presence of diabetes mellitus (odds ratio: 0.36, 95% CI: 0.27-0.49, p<0.001). Conclusion: Despite the high awareness rates, there was a high proportion of adults who did not receive treatment or achieve recommended levels of LDL-C during treatment. The low treatment and control levels among individuals based on their CHD risk levels call for a better application of recommendations regarding personal preventive measures and treatments in Turkey
Evaluating the Relationship between Diabetes and Cancer in a Cohort
No full textBACKGROUND/AIM: Epidemiological studies indicate that the risk of several types of cancer is high in diabetic patients. The aim of this study is to evaluate the association between diabetes and diabetes related cancers in a cohort design. MATERIALS AND METHODS: The baseline survey was conducted as a community screening programme from 2007 to 2009 in a population over 30 years of age. Diabetes definition was based on fasting blood glucose level ≥ 126 mg/dl and self-reported diabetes history. Data on incident cancer cases and pathological types were obtained from the İzmir Cancer Registry between 2007-2013. Odds ratios (OR) were estimated for the relationship between diabetes and diabetes-related cancer types for men and women separately and adjusted for BMI and age. Odds Ratio and 95% confidence intervals were calculated using logistic regression models in IBM SPSS Statistics 24.0. RESULTS: Data from 10,375 women (65.4%) and 5,494 men (34.6%) who did not declare any cancer in 2007 were evaluated. The cumulative incidence of diabetes related cancers was 2,293 per 100,000 in men and 1,455 per 100,000 in women. Total diabetes related cancer incidence was higher in diabetics (3,770 per 100,000) than nondiabetics (2,109 per 100,000) in men. CONCLUSION: There was no statistically significant association between diabetes and cancers. The analyses can be repeated in the future when the cohort gets older and more incident cases of cancers occur
Health-Related Quality of Life and Perceived Health Status of Turkish Population
No full textPurpose; This study was conducted to assess the health-related quality of life (HRQOL) and perceived health status of the Turkish population. Methods The data came from a nationwide survey, which was conducted by Ministry of Health on prevalence and risk factors for chronic diseases in Turkey, with a representative random sample of 18,477 people aged >= 15 years from Turkey. Each family physician invited two individuals selected from their registered population to the Family Health Center, conducted the survey by face to face interviews using an electronic form. HRQOL was determined using EQ-5D-3L scale. Results In Turkish population, each four women out of 10, two men out of 10 have problems in pain/discomfort and anxiety/depression dimensions of the scale; three women out of 10, one man out of 10 have some or severe problems in mobility. Proportion of people without health problems (health state 11,111) were 64,1% in men, 40,7% in women. The mean VAS score for males was 71.50.2 (95% CI 70.9-72.1), 66.4 +/- 0.2 (95% CI 65.8-66.9) for females (p 0.05).The most important determinants of having a problem in any of the five dimensions are age, gender, education, diabetes mellitus, coronary heart disease, stroke, alzheimer, cancer, renal failure. The OR of having some or severe problems in any dimensions was 4.6 (95% CI 38-5.4) for over 65-74 and 7.5 (95% CI 5.8-9.6) for over 75 compared to 15-24 age group. Conclusions: The perceived health level and HRQOL is worse in women, in older age groups, in people from lower socioeconomical status.Ministry of Health of Turkey; World Bank GroupThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was financially supported by the Ministry of Health of Turkey. Funding was provided by World Bank Group (Grant No. LN-7717-TU)
Smoking Cessation and the Effect of Nicotine Dependence on Relapse Rate in İzmir, Turkey
No full textBackground/aim: Smoking is the leading preventable cause of death in the world. There is growing evidence of the need for community-based programs on smoking cessation. The main purpose of this study is to establish the rate of smoking cessation and restarting in 1 year at the Balcova Smoking Cessation Center. Materials and methods: This is a prospective study with a study group of 359 individuals who quit smoking at the Balcova Smoking Cessation Center for at least 4 weeks between October 2009 and April 2010. The outcomes of the study were 1-year cessation rate and relapse rate. Individuals who reported restarting and/or had CO measurements above 6 ppm were accepted as quitters who had relapsed. Results: The 1-year rate of smoking cessation was 30.1% for the study group. Of the subjects who quit smoking, 50.1% started smoking again during the 1-year follow-up. Relapse rate was also higher in nicotine addicts. Pharmacological treatment was associated with increased success rates in smoking cessation. Conclusion: Nicotine dependency was shown to be associated with lower rates of smoking cessation and higher rates of relapse. Therefore, it is important to begin smoking cessation attempts before individuals become serious addicts.WoSScopu
Prognostic effect of thoracic radiotherapy dose after chemotherapy in extensive stage small cell lung cancer patients
No full textFrom antepartum to postpartum - A prospective study on the prevalence of peripartum depression in a semiurban Turkish community
No full textOBJECTIVE: To examine the prevalence of depression in the last trimester of pregnancy and within the first 6 months postpartum, to determine whether there is an association between antepartum and postpartum depression and to investigate the risk factors prospectively in a cohort of Turkish women. STUDY DESIGN: In a prospective, community-based, cohort study, 125 women who expected to give birth during the first 6 months of 2002 (January 1, 2002-June 30, 2002) were included. Depression was measured at 36-38 weeks antepartum and then again at 5-8, 10-14 and 20-26 weeks postpartum using the Edinburgh Postnatal Depression Scale. A questionnaire that was devised to collect data on sociodemographic and clinical information on the women was applied. RESULTS: The prevalence of depression was highest in pregnancy (21.6%) and declined gradually in the follow-up period (respectively, 16.8%, 14.4% and 9.6%). Antepartum depression was a statistically significant risk factor during the 6 months postpartum in each of the 3 assessments. In the logistic model, past history of mental illness, history of mental illness in first-degree relatives and adverse life events were associated with antepartum depression; low income, adverse life events and a poor relationship with the husband were associated with postpartum depression. CONCLUSION: Evaluations made in the last trimester of pregnancy should be very helpful in diagnosing and preventing depression in women at high risk
Prevalence of Alcohol Use in Istanbul
No full text The current research assessed the prevalence of alcohol use in Istanbul, Turkey along with characteristics and severity of related problems. The data were collected from structured interviews including the CAGE Questionnaire to eliminate the severity of alcohol-related problems of 1,550 residents (743 women, 807 men) of Istanbul, ages 12 to 65 years. Current alcohol use was 25.6% (397 persons, 118 women and 279 men), including 15.9% of the women and 34.5% of the men. 67% reported never having used alcohol. The rate of alcohol use was highest in the 40- to 49-yr. age group; the onset of use was reported as most common for the 16- to 19-yr.-olds. Prevalence of risky drinking was 6.8% (106 persons). Men were more likely to have an earlier initiation to alcohol use, to consume more [5.2 standard drinks (SD = 3.4) vs 3.6 standard drinks ( SD = 2.5)] and be problem drinkers (31.5% vs 15.2%) than women. Prevalence of alcohol use seems to be relatively low in Istanbul. Data on characteristics of alcohol use are important in estimating groups at risk for problems and in planning prevention strategies. </jats:p
Evaluation of Blood Pressure Status and Mortality in Turkey: Findings from Chronic Diseases and Risk Factors Cohort Study
No full textBackground and objectives: An important Non-Communicable Disease risk factor, hypertension (HT), is highly prevalent and controlled HT rates are not sufficient which increases the risk of developing premature deaths. The purpose of the study is to evaluate differences in all-cause and cardiovascular-related mortality according to HT status by using national data from Chronic Diseases and Risk Factors Survey in Turkey (2011–2017). Materials and Methods: Cox regression models were used to estimate hazard ratios (HR) for predicting the all-cause and cardiovascular system-related mortalities. Median follow-up period was 6.2 years. Results: Among individuals with HT, 41.8% was untreated, 30.1% received treatment and had controlled blood pressure, and 28.1% were under treatment but had uncontrolled BP levels. The hazard for mortality among treated & uncontrolled hypertensive participants was significantly higher for all-cause (HR = 1.32, 95% CI = 1.06–1.65), cardiovascular (HR = 2.11, 95% CI = 1.46–3.06), heart disease (HR = 2.24, 95% CI = 1.46–3.43), and Coronary Heart Disease mortality (HR = 2.66, 95% CI = 1.56–4.53) compared to normotensive participants. Conclusions: Individuals with HT who were treated but do not have controlled blood pressure in Turkey had a significantly increased risk of Cardiovascular Disease and all-cause mortality. Along with studies investigating the causes of uncontrolled blood pressure despite initiation of treatment, support should be provided to patients in cases of non-adherence to antihypertensive medication or life change recommendations
Comparison of Tissue and Urine Microbiota in Male, Intervention Naive Patients with and without Non-Invasive Bladder Cancer
No full textIntroduction: To investigate the presence of dysbiosis in patients with naive bladder cancer. Methods: Twelve male patients with non-invasive bladder cancer and twelve age-matched healthy males had midstream urine and tissue samples taken. A history of endourological interventions was determined as an exclusion criterion, ensuring that the study was designed solely with na & iuml;ve participants. The bacterial 16s ribosomal RNA V3-V4 regions were used to examine urine and tissue samples. We compared the microbiota composition of the bladder cancer and control groups. Results: Escherichia Shigella (p < 0.001), Staphylococcus (p < 0.001), Delftia (p < 0.001), Acinetobacter (p < 0.001), Corynebacterium (p < 0.001), and Enhydrobacter (p < 0.001) were abundant in bladder cancer tissue samples. Escherichia Shigella (p < 0.001), Ureaplasma (p < 0.001), Lactobacillus (p = 0.005), Stenotrophomonas (p < 0.001), Streptococcus (p < 0.001), Corynebacterium (p < 0.001), and Prevotella (p = 0.039) were abundant in bladder cancer urine samples. Midstream urine has a sensitivity of 83% for detecting dysbiotic bacteria in cancer tissue. Conclusions: Our research is the first microbiota study of bladder cancer done with naive patients who have never had an endourological intervention. Escherichia Shigella, Staphylococcus, Acinetobacter, Enhydrobacter, Delftia, Corynebacterium, and Pseudomonas were detected as dysbiotic bacteria in bladder cancer. The sensitivity of the midstream urine sample in detecting dysbiosis in tissue is 83%. (c) 2024 S. Karger AG, BaselScientific and Technological Research Council of Turkey (TUBITAK) [217S075]This study was supported by The Scientific and Technological Research Council of Turkey (TUBITAK) with project No. 217S075. This paper was presented as abstract at the 15th Uroocology Congress that was held in Association of UroOncology (Turkey)
