6,437 research outputs found
Father Andrew Mullen 1790-1818: a study in early nineteenth century spirituality
No full textThis thesis is laid out in three parts: Part I. The life and death of Andrew Mullen. The life is based, to a large extent, on a long letter to his mother, Catherine Mullen, dated 7 January 1810. The letter gives a definite insight into his spirituality based on his membership of the Archconfraternity of the Blessed Sacrament. There is a hint that he had a premonition of an early death. Part II. The burial of Andrew Mullen and the immediate cult to him This is based on documentary evidence. Part III. Most of this part is a catalogue of testimonies taken from 1993 onwards. Then there is the conclusion on the popular devotion to Andrew Mullen stressing the theological aspect of the subject. In the course of writing the thesis it was decided to separate the documentary evidence from the oral tradition. This was advantageous in developing the thesis, and the documents provided a secure basis for the oral tradition. Two pieces of information were found in March 1997. They are death notices: 2 January 1819, The Leinster Journal and 7 January 1819, The Car low Morning Post. There is a slight discrepancy between the two on the date of his death. Also this discrepancy shows a slight difference from the date of the tombstone
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An Anglo-American Encounter in Africa: Henry M. Stanley in Abyssinia, 1868
No full textThis chapter aims to highlight an under-explored yet significant episode in Stanley’s career: the Abyssinian expedition was his first encounter with Africa. Stanley’s accounts of the expedition provide an informative record of the transatlantic competition and innovation that drove the transformation of journalism in the late 19th century. They also established a model for the reporting of imperial wars, in which trauma and vulnerability were emphasized in order to amplify the eventual triumph. I argue here that Stanley’s reports were at the leading edge of developments in journalism, both in stylistic and in narrative terms. As Stanley established his own voice, he also shaped the dominant mode of imperial reportage. His correspondence from Abyssinia must be understood in the context of “a revolution in journalism” in which a new emphasis on “human interest, visual matter, typographical boldness and rapid, speedy news coverage” emerged first in the United States press and shortly afterwards in British publications (James 191; Wiener, Americanization, 3–4). That emergent style of journalism was referred to – often pejoratively – as the Yellow Journalism in the United States and as the New Journalism in Britain. A high level of expenditure on special correspondents gathering and making sensational news was a major feature of the emerging style of journalism. Literary Journalism as it is understood today would not have been possible without these developments
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Population genomics and phylogeography of a benthic coastal shark (Scyliorhinus canicula) using 2b-RAD single nucleotide polymorphisms
No full textThe existence of strong genetic structure is expected in species with limited ability to disperse and philopatric behaviour. These life-history traits are found in many small benthic elasmobranchs, such as in the small-spotted catshark (Scyliorhinus canicula). However, no evidence of genetic structure was found across its northeastern Atlantic (NEA) range using traditional molecular markers. Here, fine-scale genetic differentiation was detected between the British Isles and southern Iberia using 2674 single nucleotide polymorphism loci generated using 2b-restriction site-associated DNA (2b-RAD). Geographical distance and historical demography were two major drivers shaping the distribution of genetic diversity of S. canicula along the NEA. Significant positive spatial autocorrelation of allelic frequencies was detected, with genetic differentiation generally increasing with geographical distance. However, marked genetic divergence of the Celtic Sea and South Portugal collections from their closest neighbours resulted in geographically constrained genetic breaks south of the British Isles and off southwestern Iberia. Historical demographic reconstruction of population pairs across these genetic breaks suggested a scenario of historical isolation before secondary contact, probably related to distinct northern and southern glacial refugia. These results provide new insights into the population structure of S. canicula along the NEA and serve as a reference for benthic elasmobranchs with similar distribution range
Context for the ESA ExoMars rover: the Panoramic Camera (PanCam) instrument
No full textThe recently approved ExoMars rover is the first element of the ESA Aurora programme and is scheduled to deliver the Pasteur exobiology payload to Mars by 2015. The 0.7 kg Panoramic Camera will provide multi-spectral stereo images with 65 ° field-of-view (1.1 mrad/pixel) and high-resolution (85 μrad/pixel) monoscopic ‘zoom’ images with 5 ° field-of-view. The stereo wide-angle cameras (WAC) are based on the Beagle 2 Stereo Camera System heritage (Griffiths et al. (2005). Planet. Space Sci. 53, 1466–1488). The Panoramic Camera instrument is designed to fulfil the digital terrain mapping requirements of the mission as well as to provide multi-spectral geological imaging, colour and stereo panoramic images, water vapour abundance and dust optical depth measurements. It can also be used for high-resolution imaging of inaccessible locations on crater walls and to observe retrieved subsurface samples before ingestion into the rest of the Pasteur payload
The Grouped Author-Topic Model for Unsupervised Entity Resolution
No full textThis paper describes a generative approach for tackling the problem of identity resolution in a completely unsupervised context with no fixed assumption regarding the true number of identities. The problem of entity resolution involves associating different references to authors (in a paper's author list, for example) with real underlying identities. The references may be written in differing forms or may have errors, and identical references may refer to different real identities. The approach taken here uses a generative model of both the abstract of a document and its list of authors to resolve identities in a corpus of documents. In the model, authors and topics are associated with latent groups. For each document, an abstract and an author list are generated conditioned on a given group. Results are presented on real-world datasets, and outperform the best performing unsupervised methods.</p
Complete resolution of psoriasis is associated with greater improvements in itch and health-related quality of life: an analysis from UNCOVER-2, a phase 3 clinical trial of ixekizumab
No full textScalar soliton quantization with generic moduli
No full textThis article is distributed under the terms of the Creative Commons
Attribution License (CC-BY 4.0), which permits any use, distribution and reproduction in
any medium, provided the original author(s) and source are credArticle funded by SCOAP3. CP is
a Royal Society Research Fellow and partly supported by the U.S. Department of Energy
under grants DOE-SC0010008, DOE-ARRA-SC0003883 and DOE-DE-SC0007897. ABR
is supported by the Mitchell Family Foundation. We would like to thank the Mitchell
Institute at Texas A&M and the NHETC at Rutgers University respectively for hospitality
during the course of this work. We would also like to acknowledge the Aspen Center
for Physics and NSF grant 1066293 for a stimulating research environment which led to
questions addressed in this paper
Engineering semiconductor quantum dots for quantitative imaging of cell motility and invasion
No full textQuantum dots (QDs) are photo-luminescent nanocrystals that possess unique optical properties such as a narrow emission range and high photo-stability, which makes them useful for a variety of biological imaging applications. In this study, QDs presenting different chemical moieties were used to quantify non-specific binding to different extracellular matrix (ECM) proteins. QDs coated with poly-maleic anhydride (PMA), which had been modified to present alkane, alkene, alkyne, PEG and carboxylic acid, carboxylic acid, and solely PEG, were incubated on poly-l-lysine, collagen, fibronectin, and gelatin coated glass coverslips. Based upon the emission intensity normalized by the quantum yield (QY), the binding of the QDs were directly compared. The QD coated substrates exhibited photoluminescent enhancement (PLE) resulting in an increased emission intensity when excited over time. Based upon this increase, a more accurate QY was calculated, allowing for proper comparison between the QDs. Different ECM proteins possessed different binding affinities to different chemical moieties. Poly-L-lysine was shown to bind well to PEG/carboxylic acid particles, but paradoxically, not as well to carboxylic acid. Collagen exhibited an affinity to the alkyne coated particles. Fibronectin showed high binding to PEG/carboxylic acid QDs, but also bound well to the alkane, alkene, and alkyne. Gelatin, like fibronectin, also showed affinity to most of the particles. Due to differences in the QY and PLE, the QDs that bound the most to each protein did not produce the most uniform and brightest substrates.
MDA-MB-231 human breast cancer cells were then seeded on gelatin substrates coated with the QDs for 24 hours. Evidence of uptake and degradation of the matrix was observed, but could not be quantified using wide-field fluorescent microscopy. As a result, confocal images were required to properly characterize the degradation.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2017-12-01The student, Andrew Zhao, accepted the attached license on 2015-12-11 at 12:16.The student, Andrew Zhao, submitted this Thesis for approval on 2015-12-11 at 12:19.This Thesis was approved for publication on 2015-12-11 at 13:52.DSpace SAF Submission Ingestion Package generated from Vireo submission #9016 on 2016-03-02 at 14:07:55Made available in DSpace on 2016-03-02T20:24:20Z (GMT). No. of bitstreams: 2
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Household accessibility to heat refuges: Residential air conditioning, public cooled space, and walkability.
No full textabstract: Access to air conditioned space is critical for protecting urban populations from the adverse effects of heat exposure. Yet there remains fairly limited knowledge of the penetration of private (home air conditioning) and distribution of public (cooling centers and commercial space) cooled space across cities. Furthermore, the deployment of government-sponsored cooling centers is likely to be inadequately informed with respect to the location of existing cooling resources (residential air conditioning and air conditioned public space), raising questions of the equitability of access to heat refuges. We explore the distribution of private and public cooling resources and access inequities at the household level in two major US urban areas: Los Angeles County, California and Maricopa County, Arizona (whose county seat is Phoenix). We evaluate the presence of in-home air conditioning and develop a walking-based accessibility measure to air conditioned public space using a combined cumulative opportunities-gravity approach. We find significant variations in the distribution of residential air conditioning across both regions which are largely attributable to building age and inter/intra-regional climate differences. There are also regional disparities in walkable access to public cooled space. At average walking speeds, we find that official cooling centers are only accessible to a small fraction of households (3% in Los Angeles, 2% in Maricopa) while a significantly higher number of households (80% in Los Angeles, 39% in Maricopa) have access to at least one other type of public cooling resource such as a library or commercial establishment. Aggregated to a neighborhood level, we find that there are areas within each region where access to cooled space (either public or private) is limited which may increase heat-related health risks.Corresponding Author:
Andrew M. Fraser
Arizona State University
[email protected]
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