106 research outputs found
The Vitality of the Author
No full textElen Caldecott considers the impact of being physically present in a Creative Writing classroom after a period of remote learning
Writing for Young People : Critical Readings and Discussions on Craft
No full textApplying the approach of 'reading-as-a-writer' to the craft of writing for young people, this textbook combines critical analysis, unique author-insight and practical application of ideas to give writers the skills to create successful fiction for youth audiences. Under the guidance of children's author Elen Caldecott, compelling close readings dig deep into the construction of modern classics and contemporary middle grade, YA, picture books and more to explore how paragraphs, sentences and words engineer specific reader responses. Interviews with the author of the extracted work follow before each chapter rounds off with writing exercises that prompt writers to engage with techniques and ideas discussed
The Public Nature of Private Law?
No full textIn this paper the author challenges the liberal vision of the private sphere as a realm of in which agents are justified in acting without taking into consideration anyone else’s interests. The private realm cannot be thought in isolation of private law, which should in turn be conceived as an embodiment of the mutual interest of the members of that group in the flourishing of one another
Travelling Through Time on My Quest to be a Children’s Author
No full textIn her quest to become a published children’s author, Charlotte Teeple-Salas explores why she is compelled to write time-slip stories, and whether their appeal in the publishing industry is a passing trend, cyclical or enduring. Includes thoughts on writing her current project, a romantic Young Adult (YA) time-slip suspense.
Characterisation of TES, the novel focal adhesion protein
No full textEThOS - Electronic Theses Online ServiceGBUnited Kingdo
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling.
No full textContains fulltext :
70806.pdf (Publisher’s version ) (Closed access)Large brain size is one of the defining characteristics of modern humans. Seckel syndrome (MIM 210600), a disorder of markedly reduced brain and body size, is associated with defective ATR-dependent DNA damage signaling. Only a single hypomorphic mutation of ATR has been identified in this genetically heterogeneous condition. We now report that mutations in the gene encoding pericentrin (PCNT)--resulting in the loss of pericentrin from the centrosome, where it has key functions anchoring both structural and regulatory proteins--also cause Seckel syndrome. Furthermore, we find that cells of individuals with Seckel syndrome due to mutations in PCNT (PCNT-Seckel) have defects in ATR-dependent checkpoint signaling, providing the first evidence linking a structural centrosomal protein with DNA damage signaling. These findings also suggest that other known microcephaly genes implicated in either DNA repair responses or centrosomal function may act in common developmental pathways determining human brain and body size
Crafting the "Common Will." The IGC 1996 from an Austrian Perspective. IHS Political Science Series No. 52, December 1997
No full textThe paper analyses the negotiations that took place in the framework of the Intergovernmental Conference (IGC) 1996/97 leading to the modification and amendment of the founding treaties of the European communities. Taking the Austrian case as an example the interaction between the various actors at the national and the international level is reconstructed. The author criticises the “intergovernmental approach” to the analysis of decision making mechanisms in the EU showing that the negotiations did not follow the logic of state power and multilateral bargaining but a “logic of mutual adaptation of expectations and positions”. The IGC 1996/97 exemplifies the ongoing institutionalisation of peculiar decision making procedures and the proliferation of working methods that were developed in the various arenas of European negotiations. A key element of these methods is the importance of mediating roles like the role played by the Council presidency during the IGC. It is argued that the Amsterdam Treaty represents some sort of a “common will” rather than a diplomatic bargain between sovereign states. This is due to the particular setting of the IGC 1996/97 and organisational arrangements that undermine the boundaries between the intergovernmental and the supranational, the national and the international arena, between international and domestic negotiations, and between the national and the European interest
Intuition In Decision-Making: Review, Map Of Influential Researchers, And Research Agenda
No full textObjetivo: Identificar os grupos informais de redes, a estrutura e a evolução longitudinal da história intelectual da intuição na tomada de decisão nos últimos 52 anos. Método: Métodos mistos foram usados, análise de redes sociais de 887 artigos, juntamente com a revisão sistemática da literatura e análise de conteúdo das principais publicações. Principais Resultados: Os resultados indicam duas correntes teóricas que estavam implícitas na literatura: pesquisadores que entendem a intuição relacionada à experiência e seguem a abordagem padrão-intervencionista e pesquisadores que entendem a importância dos elementos sensoriais, afetivos, juntamente com a experiência; e seguem a abordagem competitivaparalela. Um fluxo com os marcos da intuição na tomada de decisão é apresentado dividido em quatro etapas: construção do conceito, validação, aplicação empírica e estudos emergentes. Contribuições: Este estudo contribui teoricamente, oferecendo uma revisão da temática diferente do que os outros estudos encontraram, por meio da apresentação de um mapa de pesquisadores influentes, seus seguidores, posicionamento teórico e metodológico dos autores e agenda de pesquisa para estudos futuros. Também oferece contribuições práticas ao apresentar o tema de forma estruturada, os gestores e empreendedores podem refletir sobre suas práticas e analisar se tem usado (e como) intuição na tomada de decisão. Também pode estimular reflexões e aplicação de ferramentas no ensino e treinamento sobre a temática. Originalidade: Este é o primeiro estudo a aplicar a técnica de redes sociais e a análise do caminho principal para entender a intuição, o que permitiu alguns avanços no conhecimento sobre a temática, demostrado nos resultados e contribuições.Full Tex
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