1,720,963 research outputs found
Tingkat Pengetahuan, Sikap dan Tindakan Mahasiswa Fakultas Kedokteran USU Terhadap Pemeriksaan Serologi Covid-19
No full textBackground. At the end of 2019, the world was shocked by the SARS-CoV-2 virus in China. This virus is named as COVID-19. The latest data on COVID-19 cases as of June 2, 2021, WHO reported globally, there were 170,812,850 confirmed cases of COVID-19, including 3,557,586 deaths, which were reported. In this pandemic condition, to be able to protect a population that was once vulnerable, it is necessary to have the status of someone who has contact with COVID-19 patients quickly by conducting laboratory tests for COVID-19. So that proper knowledge regarding the use of laboratory tests for the diagnosis of coronavirus disease is very necessary. Purpose. Knowing the level of knowledge, attitudes and actions of USU Faculty of Medicine students towards COVID-19 serology tests. Method. The type of research used is a descriptive observational research design using a cross sectional approach. The sample of this study was 343 medical students at the University of North Sumatra, which were taken using a simple random sampling technique and met the inclusion criteria. Data taken directly from respondents through the Google Form application (online) and carried out by video call. Primary data will be presented in the form of tables or graphs and pictures of frequency distribution distribution diagrams. The results of this research will be carried out in an accredited national journal. Results. Analysis of the results showed that 331 people (96.5%) had a good level of knowledge, while 12 people (3.5%). In the attitude level analysis, there are 253 students (73.8%), the sufficient category is 87 students (24.4%) and the less category is 3 students (0.9%). At the action level, there were 258 (75.2%) good predicates, while 85 people (24.8%). Conclusion. The level of knowledge, attitudes and actions of USU Faculty of Medicine students regarding the main COVID-19 serological examination is good.Latar Belakang. Pada akhir tahun 2019, dunia dikejutkan dengan virus SARS-COV-2 yang teridentifikasi di cina. Virus ini dinamai sebagai COVID-19. Data terbaru kasus COVID-19 pada 2 Juni 2021, WHO melaporkan Secara global, terdapat 170.812.850 kasus COVID-19 yang dikonfirmasi, termasuk 3.557.586 kematian, yang dilaporkan. Pada kondisi pandemi ini, untuk dapat memproteksi populasi yang rentan maka diperlukan status dari seseorang yang pernah kontak dengan pasien COVID-19 secara cepat dengan melakukan pemeriksaan laboratorium terhadap COVID-19. Sehingga pengetahuan yang tepat mengenai penggunaan tes laboratorium untuk diagnosis penyakit coronavirus sangat diperlukan. Tujuan. Mengetahui tingkat pengetahuan, sikap dan tindakan mahasiswa Fakultas Kedokteran USU terhadap pemeriksaan serologi COVID-19. Metode. Jenis penelitian yang digunakan adalah desain penelitian deskriptif observasional dengan menggunakan pendekatan cross sectional. Sampel penelitian ini sebesar 343 mahasiswa fakultas kedokteran universitas sumatera utara yang diambil dengan teknik simple random sampling dan memenuhi kriteria inklusi. Data yang dikumpulkan diambil langsung dari responden melalui aplikasi Google Form (online) dan diawasi dengan video call. Data primer akan disajikan dalam bentuk tabel atau grafik dan gambar diagram distribusi frekuensi. Hasil penelitian ini akan dipublikasikan pada jurnal nasional terakreditasi. Hasil. Analisis hasil penelitian menunjukkan 331 orang (96,5%) memiliki tingkat pengetahuan yang baik, sedangkan yang tergolong predikat cukup ialah 12 orang (3,5%). Pada analisis tingkat sikap dengan kategori baik yaitu 253 mahasiswa (73,8%), kategori cukup sebesar 87 mahasiswa (24,4%) dan kategori kurang sebesar 3 mahasiswa (0,9%). Pada tingkat tindakan didapatkan predikat baik ialah 258 (75,2%), sedangkan yang tergolong predikat cukup ialah 85 orang (24,8%). Kesimpulan. Tingkat pengetahuan, sikap dan tindakan mahasiswa Fakultas Kedokteran USU mengenai pemeriksaan serologi COVID-19 mayoritas adalah baik.107 HalamanSkripsi Sarjan
Gambaran Pengetahuan, Sikap, dan Tindakan Donor Darah pada Mahasiswa Fakultas Hukum Universitas Sumatera Utara
No full textLatar belakang. Donor darah merupakan salah satu bagian penting dalam bidang kesehatan. Donor darah dibutuhkan untuk menangani pasien yang mengalami perdarahan masif, pasien anemia berat, pasien yang hendak menjalani tindakan operasi, pasien dengan kelainan darah bawaan dan sebagainya. Kebutuhan darah juga meningkat bersamaan dengan meningkatnya jumlah penderita penyakit kelainan darah seperti haemofilia,dan talasemia. Berdasarkan data PMI pada tahun 2014 prevalensi pendonor darah pada usia 17-30 tahun yaitu hanya sebesar 25,39 %. Mahasiswa merupakan kelompok masyarakat yang berada pada kategori usia tersebut dan dianggap sebagai bagian yang sangat penting dari seluruh populasi donor darah.
Tujuan. Tujuan penelitian ini adalah untuk mengetahui gambaran pengetahuan, sikap,dan tindakan Donor Darah pada Mahasiswa Fakultas Hukum Universitas Sumatera Utara.
Metode. Penelitian ini merupakan penelitian deskriptif dengan pendekatan cross-sectional. Sampel berjumlah 85 orang dan sampel diambil dengan menggunakan simple random sampling. Data diambil dengan menggunakan kuesioner.
Hasil. Pengetahuan responden tentang donor darah sebagian besar cukup yaitu 50,6%. Sikap responden terhadap donor darah sebagian besar baik yaitu 83,5%. Tindakan responden untuk donor darah sebagian besar kurang yaitu 71,8%.
Kesimpulan. Mahasiswa Fakultas Hukum Universitas Sumatera Utara sebagian besar memiliki pengetahuan yang cukup tentang donor darah (50,6%), namun memiliki sikap yang baik terhadap donor darah (83,5%), dan tindakan yang kurang terhadap donor darah (71,8%).Background. Blood donors is an important part of the health sector. Blood donors is needed to treat patients who experience massive bleeding, patients with severe anemia, patients who are about to undergo surgery, patients with congenital blood disorders and so on. Blood requirements also increase along with the increasing number of people with blood disorders such as haemophilia and thalassemia. Based on PMI data in 2014, the prevalence of blood donors at the age of 17-30 years is only 25.39%. Students are a group of people who fall into this age category and are considered a very important part of the entire blood donor population.
Objective. To know description of knowledge, attitude, and blood donor practice of college student at Law Faculty of Sumatera Utara University.
Method. This research was a descriptive study with cross-sectional design. Amount of sample is 85 person and to get the sample used simple random sampling. Data got used quesioner.
Result. Sample knowledge about blood donor in a large part is enough (50,6%). Sample attitude toward blood donor in a large part is good (83,5%). Sample practice in a large part is never done blood donor (71,8%).
Conclusion. College student at Law Faculty of Sumatera Utara University in a large part have a enough knowledge about blood donor (50,6%), good attitude toward blood donor (83,5%), but never done blood donor (71,8%).88 HalamanSkripsi Sarjan
Correlation Between Platelet Distribution Width and Mean Platelet Volume with Hematocrit in Dengue Hemorrhagic Patients at Prof. Dr. Chairuddin Panusunan Lubis Hospital Universitas Sumatera Utara
No full textBackground. Dengue Hemorrhagic Fever (DHF) is a dengue virus (DENV) infection through the bite of an infected mosquito that manifests clinically in the form of high fever, headache, muscle pain, nausea, and rash. Research shows that several regions in Southeast Asia, including Indonesia, will experience an increase in the incidence of dengue infection in 2050 and 2080. Establishing a diagnosis of DHF can be assisted by laboratory tests of complete blood counts, including platelet distribution width (PDW), mean platelet volume (MPV), and hematocrit (Hct). Objective. This study aims to determine the correlation between platelet distribution width (PDW) and mean platelet volume (MPV) with hematocrit (Hct) in patients with Dengue Hemorrhagic Fever (DHF) at the Prof. dr. Chairuddin Panusunan Lubis Teaching Hospital, University of North Sumatra. Methods. This study was conducted with a cross-sectional design. The subjects of this study were 142 DHF patients aged > 17 years obtained from medical record data at the Prof. dr. Chairuddin Panusunan Lubis Hospital, University of North Sumatra. Statistical analysis using Pearson Correlation Test. Results and Discussion. In 142 study subjects, it was found that the majority of patients were in the age range of 18-39 years (83,8%) and were male (51.4%). The majority of patients had normal PDW values (85.2%), normal MPV values (91.5%), and normal hematocrit values (59.1%). The results of the Pearson's r correlation test between PDW and MPV with Hct obtained a p-value> 0.05. Conclusion. No significant correlation was found between PDW and MPV with Hct in DHF patients.92 PagesSkripsi Sarjan
Gambaran Pengetahuan dan Perilaku Masyarakat Medan Beretnis Tionghoa terhadap Kanker Hati Primer
Full text linkBackground: Liver Cancer is the fourth highest cancer in Indonesia. According to WHO, 21,392 people in Indonesia suffer from Liver cancer and 20,920 people died from it. Hepatitis B(HBV), Hepatitis C(HCV), followed by unhealthy lifestyles are the risk factors of Primary Liver Cancer. Adopting a good and healthy lifestyle can reduce the risk and anticipate the increasing case of Primary Liver Cancer. However, research related to these topic is yet to be found in Indonesia. Furthermore, previous research shows Chinese ethnicity has an increasing case of Primary Liver Cancer along with the drinking culture. Method: The method used in this research is cross-sectional by distributing validated questionnaire in person. This research started in June 2023 and ended in August 2023 Aim: To understand the knowledge and behaviour of Medan citizens with Chinese ethnicity regarding Primary Liver Cancer. Result and Discussion: Result of this research shows the lack of understanding in Primary Liver Cancer and sufficient behaviour in preventing Primary Liver Cancer. There are little research related to this topic in Indonesia. Therefore, the result of this research can illustrates the knowledge and behaviour of Medan citizens with Chinese ethnicity concerning Primary Liver Cancer. Nevertheless, there are limitations in this research such as no measurement to show the exact amount of alcohol consumed, no concrete evidence that can prove the family history of HCC. Conclusion: Based on the result, education about Primary Liver Cancer is needed. It can be done through seminar, webinar, community service and so forth.113 HalamanSkripsi Sarjan
Perbandingan Kadar Gula Darah Sewaktu dan Indeks Masa Tubuh Mahasiswa Baru Fakultas Kedokteran USU Angkatan 2018 Sebelum dan Sesudah Perkuliahan Semester Awal
No full textLatar Belakang. Kadar Gula Darah (KGD) adalah sesuatu yang mengacu kepada tingkatan
konsentrasi gula di dalam darah. Faktor – faktor yang dapat mempengaruhi KGD adalah usia,
hormon, emosi, stress, jumlah dan jenis makanan yang dikonsumsi serta aktivitas fisik Kadar Gula
Darah dalam tubuh berkaitan erat dengan gaya hidup yaitu pola makan dan aktivitas fisik.Dengan
aktivitas yang rendah, maka akan terjadi penimbunan kalori dan gula dalam tubuh. Indeks Massa
Tubuh (IMT) menjadi salah satu metode untuk mengukur berat badan ideal seseorang, dengan
mengukur tinngi bdan dan berat badan. IMT juga dipengaruhi oleh pola makan dan aktivitas
fisik.Kuliah, menjadi salah satu contoh dari aktifitas fisik.Perkuliahan dengan metode KBK
(Kuliah Berbasis Kompetensi) merupakan metode pembelajaran yang berpusat kepada mahasiswa
dan diharapkan bahawa mahasiswa dapat memiliki kemampuan keterampilan individu di bidang
ilmu kedokteran..Tujuan. Penelitian ini bertujuan untuk mendapatkan data perbandingan kadar
gula darah sewaktu dan indeks massa tubuh mahasiswa baru angkatan 2018 Fakultas Kedokteran
USU sebelum dan sesudah perkuliahan semester awal. Metode. Penelitian ini bersifat
observasional analitik dengan desain cross sectional. Sampel dalam penelitian ini diambil dengan
teknik simple random sampling, Penelitian ini dihitung terlebih dahulu jumlah subjek dalam
populasi lalu menggunakan rumus dan dipilih secara acak sebanyak 97 sampel. Data yang
dikumpulkan adalah data primer yang diambil secara langsung di Fakultas Kedokteran. Hasil.
Pada penelitian ini didapatkan hasil yang signifikan pada kadar gula darah sewaktu sebelum dan
sesudah perkuliahan semester awal dengan nilai p = 0,028 dan hasil yang signifikan pada IMT
sebelum dan sesudah perkuliahan semester awal dengan nilai p = 0,038. Kesimpulan. Terdapat
perbedaan perbandingan kadar gula darah sewaktu dan IMT sebelum dan sesudah perkuliahan
semester awal pada mahasiswa baru angkatan 2018 FK USU.Background. Blood sugar level is something that refers to the level of sugar concentration in the
blood. Blood sugar levels can be influenced by several factors such as age, hormones, emotions,
stress, the amount and type of food consumed and physical activity. Blood sugar levels in the body
are closely related to lifestyle namely diet and physical activity. With low activity, it will happen
accumulation of calories and sugar in the body. BMI is one method for measuring one's ideal body
weight, by measuring body height and body weight. BMI is also influenced by diet and physical
activity. Lecture is one example of physical activity. Lectures using the CBEL method
(Competency Based Education Lecture) are student centered learning methods and it is expected
that students can have individual skills. Objectives. This research aimed to obtain data on
comparison of blood sugar levels and body mass index of new students in 2018 at the USU Faculty
of Medicine before and after the initial semester lectures. Method. This research was analytic
observational with cross sectional design. The sample in this research was taken by simple
random sampling technique. This research was calculated the number of subjects in the
population then using the formula and randomly selected 97 samples. The collected data are
primary data taken directly at the Faculty of Medicine. Results. In this research were obtained
significant results on blood sugar levels before and after the initial semester lecture with p =
0.028 and significant results on BMI before and after the initial semester lecture with a value of p
= 0.038. Conclusion. There was a difference in the comparison of blood sugar levels and BMI
before and after the initial semester lecture on new students of 2018 FK USU.Skripsi Sarjan
Perbedaan Nilai Neutrophil-To-Lymphocyte Ratio (NLR) dan Nilai Cycle Threshold (Ct) pada Pasien Covid-19 Derajat Sedang dan Berat di RSUP Haji Adam Malik Medan Tahun 2021
No full textBackground. Coronavirus disease 2019 (COVID-19) is a disease cause by a new type of coronavirus (SARS-CoV-2). From WHO reports as of March 28, 2022 globally there was 480.170.172 confirmed cases of COVID-19. Major cause of disease severity and death in COVID-19 patient is considered because of hyperinflammatory response. Neutrophil-to-Lymphocyte Ratio (NLR) is one of marker for inflammatory response. Other than that, viral load of SARS-CoV-2 is associated with systemic inflammation, progression of disease, and increased risk of death, and it is known that Cycle Threshold (Ct) value is considered as a proxy for viral load with an inverse correlation. Aim. To obtain the differences of NLR and Ct value between moderate and severe COVID-19. Methods. This research is an analytic observational with cross sectional design with a retrospective approach. Type of data used in this research is secondary data obtained from medical records with sample size of 70 data using simple random sampling technique. Results. The Mann-Whitney test showed there is a significant difference of NLR between moderate to severe COVID-19 (P value <0.05). And this research also found significant difference of Ct value between moderate to severe COVID-19 (P value <0.05). Conclusion. This research showed that there is significant difference of NLR and Ct value between moderate and severe COVID-19.88 HalamanSkripsi Sarjan
Efektivitas Proteksi Asam Askorbat terhadap Peroksidasi Lipid pada Mencit(Mus Musculus L) yang dipapar Plumbum secara Intraperitoneal
No full textLead (Pb) is one of the heavy metal that is poisonous for humans. Lead can be found all around us. Toxic effects are due to oxidative stress in cells and greater lipid peroxidation of tissues . This research aimed to study the effectiveness of ascorbic acid supplementation to prevent lipid peroxidation in mice exposed to lead intraperitoneally. This research was done in the Multidicipline Laboratory, Faculty of Medicine, University of Sumatera Utara, Medan. 36 mice (Mus musculus L) were divided into 9 group of 4 mice each. The first group was given aquadest and the second to the fifth group was given lead intraperitoneally in doses 20, 40 , 80 and 160 mg/kgbw respectively. The sixth to the ninth treatment groups were given oral ascorbic acid supplementation of 400 mg/kgbw daily for 7 days. These groups were given lead intraperitoneally at doses of 20mg/kgbw, 40 mg/kgbw, 80 mg/kgbw and 160 mg/kgbw one hour after the last ascorbic acid treatment. 48 hours later mice were sacrificed by cervical dislocation and blood was taken intracardially measurement of MDA levels and erythrocyte counts were made. Malondialdehyde (MDA) levels were assayed using thiobarbituric acid (TBA), and erythrocytes were counted using a binocular microscope. Data were analyzed using Anova and Kruskal Wallis test (?= 0,05). The correlation between MDA levels and erythrocyte counts were analyzed using Pearson’s test. Results of the research showed (a) Ascorbic acid at 400 mg/kgbw in the mice exposed to 20, 80 and 160 mg/kgbw lead decreased MDA levels while a 40 mg/kgbw dose of lead showed an increased MDA level in all cases the differences did not reach statistical significance (p>0.05).(b) Ascorbic acid at 400 mg/kgbw in the mice exposed to 20 and 40 mg/kgbw lead did not have any effect on the erythrocyte count but mice exposed to 80 and 160 mg/kgbw had an increased erythrocyte count in the presence of ascorbic acid. The increase did not reach statistical significance (p>0.05). (c) Oral ascorbic acid was not effective in preventing lipid peroxidation in mice intraperitoneally exposed to lead.Plumbum (Pb) merupakan salah satu logam berat yang bersifat racun bagi manusia. Pb dapat ditemukan pada semua lingkungan sekitar kita . Efek toksik Pb menyebabkan stres oksidatif sel dan meningkatkan peroksidasi lipid jaringan. Penelitian ini bertujuan untuk mengetahui efektifitas proteksi dari asam askorbat yang diberi peroral terhadap peroksidasi lipid akibat paparan Pb secara intraperitoneal. Penelitian ini dilakukan di laboratorium terpadu Fakultas Kedokteran, Universitas Sumatera Utara, Medan. Sebanyak 36 ekor mencit ( Mus musculus L ) dibagi dalam 9 kelompok, tiap kelompok terdiri dari 4 ekor mencit. Kelompok 1, hanya diberi aquadest, sedangkan kelompok ke-2 sampai ke-5 diberi Pb masing-masing dengan dosis 20, 40, 80 dan 160 mg/kgBB berturut-turut secara intraperitoneal. Kelompok perlakuan ke-6 sampai ke-9 adalah kelompok yang disupplementasi asam askorbat dosis 400 mg/kgBB peroral sehari sekali selama tujuh hari. Pada kelompok ke-6 sampai ke-9 tersebut selanjutnya diberi Pb asetat masing-masing dengan dosis 20, 40 , 80 dan 160 mg/kgBB berturut-turut secara intraperitonel satu jam setelah pemberian asam askorbat terakhir. Darah mencit diambil secara intracardial setelah dimatikan dengan cara dislokasi leher setelah 48 jam perlakuan, kemudian diukur kadar MDA dan jumlah eritrosit. Kadar MDA diukur dengan menggunakan metode asam thiobarbiturat (TBA) dan jumlah eritrosit dihitung dengan menggunakan sebuah mikroskop binokuler. Data dianalisa menggunakan uji Anova dan Kruskal Wallis (?=0.05). Korelasi antara kadar MDA dan jumlah eritrosit menggunakan korelasi Pearson. Hasil penelitian menunjukkan bahwa (a) Pemberian asam askorbat dengan dosis 400 mg/kgBB mencit yang dipaparkan Pb secara intraperitoneal pada dosis 20, 80 dan 160 mg/kgBB cenderung menurunkan kadar MDA plasma, tetapi pada dosis Pb 40 mg/kgBB sebaliknya meningkatkan kadar MDA. Semua perbedaan tersebut secara statistik tidak bermakna (p>0.05). (b) Pemberian asam askorbat dosis 400 mg/kgBB pada mencit yang dipapar Pb secara intraperitoneal dengan dosis Pb 20 dan 40 mg/kgBB, tidak berdampak pada jumlah eritrosit tetapi sebaliknya pada dosis Pb 80 dan 160 mg/kgBB, meningkatkan jumlah eritrosit. Peningkatan ini secara statistik tidak bermakna (p>0.05) (c) Asam askorbat peroral tidak efektif memproteksi timbulnya peroksidasi lipid pada mencit yang dipaparkan Pb secara intraperitoneal. en75 HalamanTesis Magiste
Relationship between Mean Platelet Volume and Platelet Distribution Width Values with the Sledai-2K Index in Systemic Lupus Erythematosus Patients
No full textBackground: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with a wide range of clinical manifestations and is characterized by alternating phases of remission and flare-ups. Platelets and their indices play an important role in the inflammatory response and immunological reactions. Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) are simple hematological parameters included in platelet indices, suspected to be associated with disease activity, and have been proposed as biomarkers of disease activity.
Objective: This study aimed to evaluate the relationship between MPV and PDW values and the SLEDAI-2K Index in patients with Systemic Lupus Erythematosus.
Methods: This was an analytical study with a cross-sectional design conducted at Adam Malik Hospital, Medan, from February to April 2025, was conducted after obtaining ethical approval and informed consent. A total of 66 SLE patients were selected using consecutive sampling and divided equally into two groups: flare and non-flare. Data were analyzed using univariate analysis, bivariate (Spearman correlation test, p < 0.05 due to non-normal data distribution), and multivariate (multiple logistic regression) analysis.
Results and Discussion: The majority of subjects were female (95.5%) with a mean age of approximately 31 years. The flare group showed lower MPV and PDW values compared to the non-flare group. A significant negative correlation was found between MPV and the SLEDAI-2K index (r = -0.424; p < 0.001), as well as between PDW and SLEDAI-2K (r = -0.429; p < 0.001). Multivariate analysis using logistic regression showed that MPV was the only independent variable significantly associated with SLE flare (OR = 0.340; p = 0.002), whereas PDW did not show a meaningful association (p = 0.858).
Conclusion and Recommendation: MPV and PDW show potential as indicators of disease activity in SLE. MPV is proven to be a strong independent predictor of SLE flare activity, whereas PDW is not. Lower MPV values are associated with increased disease activity and may serve as a simple hematological marker for predicting flares in SLE.143 PagesTesis Magiste
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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