1,000 research outputs found

    First person – Justyna Meissner

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    ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Justyna Meissner is the first author on ‘The ARF guanine nucleotide exchange factor GBF1 is targeted to Golgi membranes through a PIP-binding domain’, published in Journal of Cell Science. Justyna is a postdoctoral fellow in the laboratory of Dr Elizabeth Sztul at University of Alabama at Birmingham, USA, investigating the structure and function of large GEFs.</jats:p

    Author response

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    The ability of the adult brain to undergo plastic changes is of particular interest in medicine, especially regarding recovery from injuries or improving learning and cognition. Matrix metalloproteinases (MMPs) have been associated with juvenile experience-dependent primary visual cortex (V1) plasticity, yet little is known about their role in this process in the adult V1. Activation of MMPs is a crucial step facilitating structural changes in a healthy brain; however, upon brain injury, upregulated MMPs promote the spread of a lesion and impair recovery. To clarify these seemingly opposing outcomes of MMP-activation, we examined the effects of MMP-inhibition on experience-induced plasticity in healthy and stoke-affected adult mice. In healthy animals, 7-day application of MMP-inhibitor prevented visual plasticity. Additionally, treatment with MMP-inhibitor once but not twice following stroke rescued plasticity, normally lost under these conditions. Our data imply that an optimal level of MMP-activity is crucial for adult visual plasticity to occur

    Open House London in the background of architectural literature studies

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    The article refers to the international scientific symposium which took place in 2019 in the UK capital during the Open House London. The meeting of scholars from Warsaw and London was devoted to the assumptions of architectural literature studies and possibilities of developing this approach for research on Polish emigration in London. In the first part of the article Aleksandra Wójtowicz – an author of the approach of architectural literature studies – presents its assumptions and possibilities of implementation. She recalls the features of ‘difficult places’ – a category developed by Warsaw’s interdisciplinary team. She also mentions the principles of ‘re-imaginary architecture’ – Justyna Gorzkowicz’s proposal – referring to the category of reading identity places in exile. The second part of the article is devoted to the specics of Open House London. Justyna Gorzkowicz presents the characteristics of two Polish places that the symposium participants could get acquainted with during their visit to London: PUNO’s headquarters and Cezary Bednarski’s Vertically Detached Houses

    (No)Motion and Silence of a Picture-Thought According to JLG

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    Recenzja książki Barbary Kity Obraz zatrzymany. Praktyka i teoria późnego Godarda (2013). Justyna Budzik przedstawia strukturę wywodu naukowego Barbary Kity, komentując i opisując metodologię przyjętą przez autorkę. Recenzentka omawia problematykę refleksji podjętej przez badaczkę oraz wyjaśnia trzy główne kategorie, które stosuje ona w interpretacji późnej twórczości Jean-Luca Godarda: obraz zwolniony/zatrzymany, obraz malarski (kadr) oraz fotografię. Recenzentka zwraca również uwagę na kontekst współczesnej teorii obrazu (Georges Didi-Huberman, Gilles Deleuze), w który wpisują się rozważania podjęte przez Barbarę Kitę.A review of Barbara Kita’s book Obraz zatrzymany. Praktyka i teoria późnego Godarda [Freeze Frame: Practice and Theory of Late Godard] (2013). Justyna Budzik presents the structure of Barbara Kita’s scientific argument, and describes and comments on the methodology adopted by the author. The reviewer discusses the problem of reflection taken up by the author and explains three main categories which she applies in her interpretation of the late work of Jean-Luc Godard: slow motion/stop motion image, art painting (film frame), and photography. The reviewer also gives some attention to the context of contemporary theory of image (Georges Didi-Huberman, Gilles Deleuze) which inform Barbara Kita’s work

    Teatr i wychowanie (Theatre and Upbringing) Authors: Krzysztof Homa, Justyna Sprutta, Weronika Pudełko, Katarzyna Skulska

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    The book Teatr i wychowanie (Theatre and Upbringing) by Krzysztof Homa, Justyna Sprutta,&nbsp;Weronika Pudełko and Katarzyna Skulska presents the history of the theatre, its essence, typology,&nbsp;as well as the role of the theatre in upbringing and therapy, especially for children.&nbsp;This book demonstrates, among others: • Greek mysteries as the beginning of the European theatre, • the history of the theatre in the world and Poland, • the school theatre in the past and present, • the essence of the theatre, as well as theatrical and paratheatrical genres. Moreover, in this book examples of paintings presenting the theatre are displayed. The reviewed&nbsp;book is a multi-author monograph

    „My vision of reality seems to be blurred”

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    Artykuł jest zapisem rozmowy z Katarzyną Jakubiak (ur. 1973), pisarką, tłumaczką, wykładowczynią, przeprowadzonej przez Justynę Sobolewską i Sławomira Iwasiowa w ramach Festiwalu Literatury Kobiet „Gryfia” w czerwcu 2013 roku w Szczecinie. Autorka była nominowana w tym roku do Literackiej Nagrody „Gryfia” za tom prozy Nieostre widzenia. Zarówno książka, jak i rozmowa, która toczyła się wokół poszczególnych tekstów z tego zbioru, dotyczą takich zagadnień, jak emigracyjność, literatura akademicka czy reprezentacja w utworach literackich. Pisarka, opowiadając o kolejnych etapach powstawania zbioru Nieostre widzenia, mówiła także o swoich doświadczeniach emigracyjnych, podróżach oraz pracy na uniwersytetach w Stanach Zjednoczonych i Europie. To tematyka, którą interesują się prowadzący rozmowę: Justyna Sobolewska jest uznaną krytyczką literacką, znawczynią współczesnej literatury polskiej, współpracującą z najważniejszymi mediami opiniotwórczymi (m.in. z tygodnikiem „Polityka”), natomiast Sławomir Iwasiów bada związki najnowszej prozy z takimi kategoriami, jak podróżowanie czy tożsamość.The article documents a meet-the-author session with Katarzyna Jakubiak (born in 1973) – polish writer, translator and academic teacher. The interview took place in Szczecin on June 2013 during the cultural event Festiwal Literatury Kobiet Gryfia and was moderated by Justyna Sobolewska and Sławomir Iwasiów. This year the author got nomination to award Literacka Nagroda Gryfia for collection of short stories entitled „Nieostre widzenia”. The debate between Jakubiak, Sobolewska and Iwasiów was focused on certain issues such as: emigration, academic literature and representation in prose. Jakubiak told the audience about the process of writing but also talked about emigrational experience, traveling and teaching at the American and European universities. Those are the subjects that were interesting for the interviewers: Justyna Sobolewska is a recognized literary critic, a connoisseur of modern-day Polish literature who works for major opinion leaders in media (such as weekly magazine Polityka), while Sławomir Iwasiów is a literary scholar who explores the latest Polish prose and its relationships with such categories as travel and identity

    Current advances in ischemic stroke management

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    Żyga Justyna. Current advances in ischemic stroke management. Journal of Education, Health and Sport. 2022;12(8):644-649. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.08.066 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.08.066 https://zenodo.org/record/7011773 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 05.08.2022. Revised: 07.08.2022. Accepted: 20.08.2022. Current advances in ischemic stroke management Justyna Żyga1 1Wojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego w Lublinie Corresponding author: Justyna Żyga email: [email protected] ORCID: 0000-0001-5453-1235 Abstract Stroke is one of the leading causes of morbidity and mortality worldwide with 24.1 million new stroke cases in 2017 and 700,000 more stroke-related deaths, as compared to 2016. Although some patients recover after a stroke, the significant majority continue to have numerous health problems resulting in substantial decrease of life quality. This article reviews the evaluation and the current advances in the management of acute ischemic stroke, starting in the prehospital setting followed by stroke hospital management. Conclusions: Appropriate treatment of ischemic stroke is essential in the reduction of mortality and morbidity. Therapeutic methods have greatly expanded beyond the utility of intravenous thrombolysis, with more advanced and complex techniques. Mechanical thrombectomy has revolutionised the management through the clot retrieval techniques improving patient outcomes. Appropriate application of the available treatment methods is crucial to optimising outcomes of patients with stroke, starting from pre-hospital accurate assessment. High-quality care of patients with ischemic stroke requires efficient cooperation of multidisciplinary medical staff. Keywords: ischemic stroke, mechanical thrombectomy, neurology, cerebral strok

    Intraventricular haemorrhage in premature infants. Review of diagnostic methods, treatment and influence on neurodevelopment

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    Żyga Justyna. Intraventricular haemorrhage in premature infants. Review of diagnostic methods, treatment and influence on neurodevelopment. Journal of Education, Health and Sport. 2022;12(7):262-268. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.07.025 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.07.025 https://zenodo.org/record/6790948 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.06.2022. Revised: 20.06.2022. Accepted: 02.07.2022. Intraventricular haemorrhage in premature infants. Review of diagnostic methods, treatment and influence on neurodevelopment Justyna Żyga1 1Wojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego w Lublinie Corresponding author: Justyna Żyga email: [email protected] ORCID: 0000-0001-5453-1235 Abstract Introduction: Preterm infants are at high risk for various neurological complications and mortality caused by hypoxemia, haemorrhage or inflammation concerning preterm delivery. Resulting brain lesions are mostly asymptomatic - they cannot be diagnosed clinically as such neuroimaging of preterm infants has become part of routine clinical care. In this article, newest studies about intraventricular haemorrhage, its complications and treatment methods were reviewed. The PubMed database was searched using keywords “intraventricular haemorrhage”, “preterm infant”, “intraventricular haemorrhage treatment”, “intraventricular haemorrhage outcome”. State of knowledge: Early diagnosis, appropriate nursing care and treatment can minimise morbidity. Prognosis is mainly determined by the severity of bleeding, occurred complications and neurological irreversible changes. Intraventricular haemorrhage can cause posthemorrhagic hydrocephalus, cerebral palsy, disability and mental retardation in further life. Even mild grades of haemorrhage can result in developmental disorders. Long-term issues such as neurodevelopmental disorders and cerebral palsy are as important as short-term problems. Detection of injuries affecting preterm infants is used to identify complications that might necessitate an intervention. While head ultrasound is the standard of care for routine neuroimaging screening, the use of brain magnetic resonance imaging has expanded recently. Conclusions: Considerable advances in neonatal care have resulted in improved survival and prognosis of development of preterm infants with intraventricular haemorrhage. Although there is a wide range of treatment methods, further studies are needed to assess their safety, effectiveness and impact on short- and long-term outcome. Keywords: intraventricular haemorrhage; preterm infant; intraventriculat haemorrhage treatment; preterm delivery; ultrasonography; magnetic resonance imagin

    A review of studies evaluating medical cannabis for the chronic pain management

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    Żyga Justyna. A review of studies evaluating medical cannabis for the chronic pain management. Journal of Education, Health and Sport. 2022;12(8):250-256. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.08.024 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.08.024 https://zenodo.org/record/6953815 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 17.07.2022. Revised: 27.07.2022. Accepted: 02.08.2022. A review of studies evaluating medical cannabis for the chronic pain management Justyna Żyga1 1Wojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego w Lublinie Corresponding author: Justyna Żyga email: [email protected] ORCID: 0000-0001-5453-1235 Abstract Introduction: Medical cannabis for patients with chronic pain related to various conditions has been the focus of numerous investigations. Cannabis-based medicine has been described for hundreds of years but only recently have we seen the more scientific, evidence-based approach to its use, and ongoing investigations continue to explore its potential medical benefits. State of knowledge: As the results of studies assessing medical cannabis in pain alleviate seem promising, only weak recommendations are available. Important factors to consider in the development of guidelines include optimal doses, routes of administration and used types of cannabinoids. In discussed studies no serious adverse events were reported and treatment was well tolerated by participants. Conclusions: Evidence suggests that cannabis-based medicine can be safe and effective in pain relief. Further high-quality randomised clinical trial studies are needed. It is important to assess the safety profile of each individual cannabinoid formulation and define the population that can benefit from cannabis therapy for establishment of prospective recommendations and guidelines. Keywords: Cannabis; endocannabinoids; Δ9-tetrahydrocannabinol; cannabidiol; chronic pai

    Pelvic Congestion syndrome - common, but underdiagnosed disease of women

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    Żyga Justyna. Pelvic Congestion syndrome - common, but underdiagnosed disease of women. Journal of Education, Health and Sport. 2022;12(7):568-572. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2022.12.07.056 https://apcz.umk.pl/JEHS/article/view/JEHS.2022.12.07.056 https://zenodo.org/record/6860379 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2022; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 03.07.2022. Revised: 17.07.2022. Accepted: 19.07.2022. Pelvic Congestion syndrome - common, but underdiagnosed disease of women Justyna Żyga1 1Wojewódzki Szpital Specjalistyczny im. Stefana Kardynała Wyszyńskiego w Lublinie Corresponding author: Justyna Żyga email: [email protected] ORCID: 0000-0001-5453-1235 Abstract Introduction: Pelvic congestion syndrome is defined as the presence of varicose changes in the ovarian veins and venous plexuses associated with chronic pelvic pain syndrome. The main problem with pelvic congestion syndrome is the low awareness of medical staff about this syndrome and the resulting very low recognition. State of knowledge: Pelvic congestion syndrome is an important cause of chronic pelvic pain. The diagnosis is based on imaging examination with ultrasound as a first-line choice and correlation with clinical presentation. The aetiology is multifactorial and may result from a combination of genetic predisposition, anatomical abnormalities, hormonal, mechanical factors with venous wall weakness, reverse blood flow and hypertension. The incidence is strongly related to the number of pregnancies. Conclusions: Pelvic congestion syndrome is one of the possible causes of chronic pelvic pain, thus differential diagnosis should necessarily include venous insufficiency during interviewing, clinical and ultrasound examination of patients. Among several treatment methods, intravascular embolization is a minimally invasive, effective and safe, currently recognised as a method of choice in treatment. Key wors: pelvic congestion syndrome; chronic pelvic pain; embolization; varicose veins; Interventional Radiolog
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