1,763 research outputs found
« Et havendo parlato co Flaminio Romano, dichiarato e sententiato eretico ». Denunce e delazioni nella Siena del xvi secolo
No full textThe trials of Niccolo Amerighi and Flaminio Fabrizi are among the most interesting within the swath of documents emerging from the recently open Archive of the Congregation for the Doctrine of the Faith. While not covering the trials and their underlying ideas, this article intends to provide the reader with a glimpse of the network that Amerighi and Fabrizi established in Siena and the impact that their trials had in the city
Resonant Inelastic X-ray Scattering at the ESRF: Hard and Soft X-rays
No full textThe technique of Resonant Inelastic X-ray Scattering (RIXS) has been exploited at the ESRF since the very early days of the facility in the 1990s. Of particular importance has been the pioneering hard X-ray work on ID16 and that by the Milano group of L. Braicovich and G. Ghiringhelli in collaboration with the ESRF at the soft X-ray beamline (originally on ID12B and then at ID08). The success of these activities has in many cases led to the development of the technique at other facilities. Both the hard and soft X-ray RIXS facilities at the ESRF will be upgraded in the next two years so it is timely to briefly outline what scientific problems can be addressed by the method, what the current status is at the ESRF, and how the experimental capabilities will be enhanced in the near future
TUTELA DEL LAVORO E LIBERTA' D'IMPRESA NEI PROCESSI DI ESTERNALIZZAZIONE
No full textL’elaborato analizza le conseguenze lavoristiche della successione fra imprenditori, muovendo da una ricognizione delle varie tipologie di esternalizzazione con le relative esigenze e principali criticità.
L’indagine si concentra in primo luogo sul trasferimento d’azienda, esaminando la normativa e la giurisprudenza europee per passare poi alla disciplina di diritto interno, alle procedure sindacali e a uno specifico focus sul trasferimento delle aziende in crisi.
Successivamente l’autore si sofferma sull’appalto, prendendone in particolare considerazione gli indici di genuinità, i criteri di distinzione dalla somministrazione illecita di manodopera e la tutela delle maestranze in caso di avvicendamento fra imprese.
Da ultimo, la ricerca approfondisce le c.d. “clausole sociali”, sia di prima che di seconda generazione, valutandone la compatibilità con il diritto eurounitario e con la costituzione nonché riflettendo sui possibili rimedi in caso di loro violazione.The author analyzes the labour consequences of the succession between entrepreneurs, starting from a recognition of the various types of outsourcing with the related needs and main critical issues.
The survey focuses primarily on the transfer of businesses, examining European legislation and case-law and then moving on to internal legislation, trade union procedures and a specific focus on the transfer of companies in crisis.
The author then dwells on the contract, taking into account in particular the indications of authenticity, the criteria of distinction from the illicit administration of labour and the protection of workers in the event of turnover between companies.
Finally, the research deepens the "social clauses", both first and second generation, assessing their compatibility with European law and with the constitution and reflecting on possible remedies in case of their violation
PARENTERAL NUTRITION AND BRANCHED CHAIN AMINO ACIDS: AN IN VIVO AND IN VITRO EVALUATION.
Get PDFParenteral nutrition (PN) offers the possibility to increase or to ensure nutrient intake, providing
nutrients in sufficient doses to meet the veterinary and human patient’s daily requirements. PN is a
complex admixture based on amino acids, dextrose, lipids. Safety issues related to parenteral nutrition
formulations have led to the development of guidelines for safe practices. The development of new
formulation and the evaluation of the already used solution is the main research in PN practice.
International guidelines are quite vague regarding the optimal doses of amino acid to administer to
malnourished patients affected by liver desease. A decreased ratio of branched-chain amino acids
(BCAA) to aromatic amino acids (AAA) is considered an important pathogenetic factor in hepatic
disease. The PN solution are composed by different compound, where the BCAAs are always
presents. Long-term oral supplementation with branched chain amino acids (BCAAs) as adjuvant
during liver injuries, both in humans and animals, is still not totally clear. Aim of the present study
was to determine how amino acids in PN and BCAAs on an in vitro study can preserve liver damage
and function. First purpose of this study was to evaluate the use of partial parenteral nutrition (PPN)
in dogs, using two different solutions: 11 dogs treated with a normal amino acidic concentration
(Medium/Low Protein Level group, Freamine concentration ≤ 25%;1,9-2,2 gr/kg/die amino
acids/proteins) as control group and 9 dogs with high-amino acid percentage (High Protein Level
group, Freamine > 25%; 3,6-6 gr/kg/die amino acids/proteins) as cases. The evaluation of the two
differents solutions is based on the liver damage during the therapy. Results reveal a not statistically
significatives differencies for liver damage between High Protein Level group and Medium/Low
Protein Level group. It means that an a hight amount of amino acids in PN could not affect and
overload the hepatic metabolism, despite carrying out their more advantage effects on body lean mass.
The second purpose and study, which is the most importan for us, was to evaluate two differents in
vitro models selected: A) hepatic rabbit cells plated in 2D monolayer and B) rabbit hepatic cells
cultured onto 3D scaffolds, obtained from decellularized rabbit liver. Both A and B cells were treated
with BCAAs. All cells adhered and proliferated, once plated. Moreover, the presence of hepatic
progenitors (HPCs), were detected by immuno staining assay and mRNA expression. However, A
cells were shown to produce albumin and FVII but quickly entered G0 and arrested growth by day
15. In contrast, cells in B, actively replicated and recellularized ECM rabbit liver, mimicking the
original organ cyto-architecture, until day 21. Interestingly, under defined conditions, BCAA
supplementation promoted vigorous growth of cell organoid and increased hepatocyte albumin and
FVII production and expression. A selective amplification of self-renewing bi-potent HPCs was also
observed. These results highlight the role of BCAAs in long term supplementation and support the
use of 3D cultures as reliable in vitro models. In conclusion, these finding suggest that an high amino
acidic diet with a high BCAAs/AAA ratio coud be a valid therapeutic option in cachectic patients or
patient with severe livere diseases
Ultra Low Carbon Vehicles: New Parameters for Automotive Design
No full textAs the influence of vehicle emissions on our environment has become better understood, the UK government has recently placed urgent emphasis on the implementation of low carbon
technologies in the automotive industry through: the UK Low Carbon Industrial Strategy. The overall objective is to offer big incentives to consumers and support for the development of infrastructure and engineering solutions. This scheme however does not consider how the development of functional and experiential user value might drive consumer demand, contributing to the adoption of low carbon vehicles (LCVs) in the mass market.
With the emergence of the North East of England as the UK’s first specialised region for the development of ultra-low carbon vehicles (ULCVs), ONE North East, as a development agency for the region's economic and business development, and Northumbria University Ideas-lab have supported a project to facilitate innovation through the collaboration of technology, research and development (R&D) and business. The High Value Low Carbon (HVLC) project aims to envisage
new user value made possible by the integration of low carbon vehicle platforms with new process and network technologies. The HVLC consortium represents vehicle manufacturers and their suppliers as well as technology based companies and through an ongoing process of design concept generation the project offers a hub for innovation led enterprise.
Whilst new technological developments in areas such as power generation, nano materials, hydrogen fuel cells, printed electronics and networked communications will all impact on future automotive design, the mass adoption of low carbon technologies represents a paradigm shift for the motorist. This paper aims to describe how the mapping of new parameters will lead to new transport scenarios that will create the space for new collaborative research on user experiences supported by innovative technologies and related services
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Matteo Maria Boiardo (1441-1494)
No full textMatteo Maria Boiardo – contemporary of Sir Thomas Malory and forerunner of Shakespeare, Spenser, Milton, Cervantes, Tolkien, and C.S. Lewis – is best known as the author of the Orlando Innamorato [Orlando in Love], a poem in ottava rima organically merging Carolingian epic and Arthurian romance. He was also a lyric and pastoral poet, playwright, and translator of classical texts into the Italian vernacular. Matteo was active in Italy during the years of 1463 throughout 1494, the year of his death
Uno sguardo all'Est. Lavoro e diritti fondamentali in Russia e negli altri Paesi della Comunità di Stati indipendenti
No full textNel contributo l'autore, dopo aver esaminato i diritti fondamentali del lavoro presenti nelle Costituzioni dei Paesi della Comunità di Stati indipendenti, si sofferma sul diritto del lavoro russo. La trattazione, a carattere diacronico, abbraccia i rami principali del diritto del lavoro: il rapporto individuale, le relazioni collettive, il mercato del lavoro. L'autore rileva una sorprendente continuità nelle linee essenziali del diritto del lavoro russo, pur nel susseguirsi di sistemi socioeconomici completamente diversi. Egli conclude che il diritto del lavoro russo appartiene saldamente alla matrice europea della materia.The contribution of the author starts by examining fundamental labour rights recognised by the Constitutions of the Countries of the Community of Independent States. Then the author focuses upon Russian Labour Law, going through the history of the main branches of the discipline: the individual relationship, industrial relations, the labour market. The article finds a surprising continuity in the essential lines of Russian Labour Law, in spite of the completely different socio-economic systems that were experimented in Russia during the twentieth century. The author concludes that Russian Labour Law clearly belongs to the European matrix of the discipline
Corpo, spazio, architettura. Fenomenologia dell’esperienza spaziale Matteo Vegetti, Fabrizia Bandi (eds.), Editrice Morcelliana, Brescia 2024
No full textThe author reviews "Corpo, spazio, architettura: Fenomenologia dell’esperienza spaziale," edited by Matteo Vegetti and Fabrizia Bandi. The book examines the philosophical underpinnings of spatial experience through a phenomenological lens, engaging with both traditional and contemporary notions of how space, body, and architecture interconnect. The author highlights the text\u27s exploration of how architects and designers might integrate phenomenological insights into their work, transforming space from mere physical dimensions into lived, experienced reality. The review appreciates the book’s thematic organization, which starts with foundational theories from Merleau-Ponty and expands through discussions on virtual spaces and the future of architecture in the digital age. Through this anthology, readers gain a comprehensive view of the architectural implications of phenomenological thought, making it a critical resource for anyone involved in the conceptualization and design of space
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