323,847 research outputs found
Piperolein B, isopiperolein B and piperamide C9:1(8E): total synthesis and cytotoxicities
Total syntheses of the reported structures of piperolein B, isopiperolein B and piperamide C9:1(8E) have been achieved. The analytical data reported for piperolein B and piperamide C9:1(8E) match the synthetic values, however those for isopiperolein B do not. The cytotoxicities of these three structurally similar compounds against cancer cell lines of different tissue origins were evaluated and the results indicated that these compounds show differential effects on cancer cell viability
Consumer Protection
Il consumatore di alimenti nella disciplina europea, con riferimento alla protezione del consumatore sia sul versante della sicurezza alimentare, sia sul versante della tutela ambientale, sia sul versante dei nuovi mercati aperti dalle tecnologie digital
Diffusive author(s), cohesive author: Analysis of S/N (1994)
This study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Droit du vin et santé publique, actes de la journée d'études du 15 janvier 2015, Université de Reims Champagne-Ardennes
Programme Vin & Droit.International audienceL'enjeu sanitaire dans la régulation de la production et de la consommation de vin relève de la recherche perpétuelle d'un équilibre entre des objectifs souvent divergents : protection du consommateur, optimisation de la production, conquête de nouveaux marchés, développement durable, sauvegarde des usages de viticulture... Si le débat n'est pas nouveau, il se pose au demeurant aujourd'hui dans des conditions inédites : progrès de la science médicale, développement de la notion de risque et de sa gestion, multiplicité des niveaux de régulation en la matière et ascension de la société civile comme acteur ou comme valeur dans la régulation de l'économie. Le présent ouvrage réunit les travaux d'une journée d'études qui s'est tenue à Reims, le 15 janvier 2015, dans le cadre du Programme Vin & Droit. Ces travaux ne prétendent pas vouloir dresser un bilan de l'ensemble des règles en matière de la vigne et du vin, lesquelles serviraient \textemdash ou compromettraient, au contraire \textemdash la cause sanitaire. Il ne s'agit pas, non plus, de se positionner par rapport à l'approche de diabolisation du vin. L'ambition de l'ouvrage est de jeter un regard nouveau à cette problématique, au-delà du dilemme santé ou alcool, par l'appréhension de différentes interventions normatives en la matière en termes de légitimité d'action et de responsabilité(s) juridique(s)
Decoding of path-guided apparent motion from neural ensembles in posterior parietal cortex
We compared quantitatively the psychometric capacity of human subjects to detect path-guided apparent motion (PAM) and the accuracy of cell ensembles in area 7a to code the same type of stimuli. Nine human subjects performed a detection task of PAM. They were instructed to indicate with a key-press whether they perceived a circularly moving object when five stimuli were flashed successively at the vertices of a regular pentagon. The stimuli were presented along a low contrast circular path with one of 33 speeds (150-600°/s). The average psychometric curve revealed that the threshold for PAM detection was 314°/s. The minimum and maximum thresholds for individual subjects were 277° and 378°/s, respectively. In addition, the activity of cells in area 7a that were modulated by the stimulus position in real or apparent motion was used in a multivariate linear regression analysis to recover the stimulus position over time. Real stimulus motion was decoded successfully from neural ensemble activity at all speeds. In contrast, the decoding of PAM was poor at low stimulus speeds but improved markedly above 300°/s: in fact, this was very close to the threshold above for human subjects to perceive continuous stimulus motion in this condition. These results suggest that the posterior parietal cortex is part of a high-level system that is directly involved in the dynamic representation of complex motion. © Springer-Verlag 2004
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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